The rigidity and well-defined size and shape of the bispidine scaffold, as well as the ease of preparing 4- to 10-dentate ligands are the main features for its very rich coordination chemistry.
Here, we show a versatile design strategy based on bispidine. The conformational study of bispidine diamides showed that syn/anti-forms exist. The bispidine–amino acid conjugate behaves like a molecular machine with stops at the syn/anti-position.
In bispidine-iron(IV)–tosylimido complexes, axial vs. equatorial NTs coordination dictates the decay: axial gives a low-spin Fe(III)–NHTs, whereas equatorial yields a high-spin Fe(III) species via self-decay resulting in N-centered demethylation.
We present a molecular topology-based strategy for creating pseudopeptosomes. These pseudopeptides showed cell penetrating property. X-ray crystal structure and spectroscopic data revealed a Trp zipper arrangement.
Synthesis, single crystal X-ray diffraction, thermal analysis and shelf life of the crystalline adducts of hydrogen peroxide with primary, secondary and tertiary amine halides obtained from aqueous H2O2 solution with a concentration of 5–97% wt.