Diazo compounds are among the most popular intermediates in organic synthesis owing to the ease and versatility of generation of metal–carbenes.
The advancements in the synthesis of nitrogen-containing heterocycles via Rh(III)-catalyzed chelation-assisted tandem C–H activation/carbene insertion/annulation with diazo compounds as carbene precursors have been summarized.
This review demonstrates the redox-neutral synthetic approaches towards valuable heterocycles such as isoquinolines, indoles, isoquinolones, and tetrahydroquinolines via high-valent Cp*Co(III) catalysis.
This article reviews the strategies available to achieve the umpolung of diazocompounds and the synthetic applications of such compounds.
We report divergent reactions of 1,2,3-triazines and 1,2,3-triazine 1-oxides with diazomethyl compounds, the former yielding diazovinylketoesters, and the latter giving rise to pyrazole derivatives through extrusion of ethyl cyanocarboxylate and N2O.