A rhodium(III)-catalyzed indole C4-selective cyanation is described using the bench-stable, user-friendly electrophilic cyanation agent N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) as a coupling partner.
An unprecedented DMAP-catalysed amidation of aryl and alkyl carboxylic acids with organo-cyanamides has been developed for the first time, enabling the efficient synthesis of a range of structurally diverse amides in useful to good yields.
Herein, we report the development of a carbon-bound radical cyanating reagent, 2-methyl-2-(pyridin-2-yl)malononitrile (MPYMN), which enables metal-free photocatalytic cyanation with high reactivity and site selectivity.
This feature review is focused on recent key applications of commonly used transition-metal Cp-type catalysts for C–H bond functionalizations.
We report a Ru-catalysed decarboxylative unsymmetric ortho-C–H azaarylation/meta-C–H alkylation via a traceless directing group relay strategy, which shows high regio- and chemoselectivity with broad substrate scopes under redox-neutral conditions.