Branched Linkers for Homogeneous Antibody-Drug Conjugates: How Long Is Long Enough?

Evgeny L. Gulyak, Olga A. Komarova, Yury A. Prokopenko, Elina A. Faizullina, Diana M. Malabuiok, Aigul R. Ibragimova, Yuliana A. Mokrushina, Oxana V. Serova, Galina P. Popova, Mikhail Y. Zhitlov, Timofei D. Nikitin, Vladimir A. Brylev, Alexey V. Ustinov, Vera A. Alferova, Vladimir A. Korshun, Ivan V. Smirnov, Stanislav S. Terekhov and Ksenia A. Sapozhnikova

IJMS, 2024, 25, 13356
DOI: 10.3390/ijms252413356

Current Trends in Clinical Trials of Prodrugs

Diogo Boreski, Valentine Fabienne Schmid, Priscila Longhin Bosquesi, Jean Leandro dos Santos, Cauê Benito Scarim, Viktor Reshetnikov and Chung Man Chin

Pharmaceuticals, 2025, 18, 210
DOI: 10.3390/ph18020210

Photocatalyzed elaboration of antibody-based bioconjugates

Marine Le Stum, Eugénie Romero and Gary A Molander

Beilstein J. Org. Chem., 2025, 21, 616
DOI: 10.3762/bjoc.21.49

Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody–Drug Conjugates

Marzieh Ahangarpour, Margaret A. Brimble and Iman Kavianinia

Bioconjugate Chem., 2024, 35, 1007
DOI: 10.1021/acs.bioconjchem.4c00199

Evolving bioanalytical strategies in the wake of pioneering biotherapeutics

Federico Riccardi Sirtori, Andrea Di Ianni, Claudio Crosasso, Elisa Bertotti, Francesco Molinaro, Ilse De Salve, Luca Barbero and Kyra J Cowan

Bioanalysis, 2025, 17, 979
DOI: 10.1080/17576180.2025.2546775

Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody–Drug Conjugates

Ferran Nadal-Bufi, Paulin L. Salomon, Fabio de Moliner, Kathy A. Sarris, Zhi Wang, Rachel D. Wills, Violeta L. Marin, Xiaona Shi, Kuo Zhou, Zhongyuan Wang, Zhou Xu, Michael J. McPherson, Christopher C. Marvin, Adrian D. Hobson and Marc Vendrell

J. Am. Chem. Soc., 2025, 147, 7578
DOI: 10.1021/jacs.4c16842