Light fractionated ALA-PDT enhances therapeutic efficacy in vitro; the influence of PpIX concentration and illumination parameters

Henriëtte S. de Bruijn, Adriana G. Casas, Gabriela Di Venosa, Lautato Gandara, Henricus J. C. M. Sterenborg, Alcira Batlle and Dominic J. Robinson

Photochem Photobiol Sci, 2013, 12, 241
DOI: 10.1039/c2pp25287b

Predicting efficacy of photodynamic therapy by real-time FDG-PET in a mouse tumour model

Nicole Cauchon, Eric Turcotte, Roger Lecomte, Haroutioun M. Hasséssian and Johan E. van Lier

Photochem Photobiol Sci, 2012, 11, 364
DOI: 10.1039/c1pp05294b

New aspects in photodynamic therapy of actinic keratoses

Tim Smits and Anne C.E. Moor

Journal of Photochemistry and Photobiology B: Biology, 2009, 96, 159
DOI: 10.1016/j.jphotobiol.2009.06.003

Fractionated photoimmunotherapy stimulates an anti-tumour immune response: an integrated mathematical and in vitro study

Mohammad U. Zahid, Matthew Waguespack, Rebecca C. Harman, Eric M. Kercher, Shubhankar Nath, Tayyaba Hasan, Imran Rizvi, Bryan Q. Spring and Heiko Enderling

Br J Cancer, 2024, 131, 1378
DOI: 10.1038/s41416-024-02844-y

Fractionated Illumination at Low Fluence Rate Photodynamic Therapy in Mice

Tom A. Middelburg, Floor Van Zaane, Henriëtte S. De Bruijn, Angelique Van Der Ploeg‐van den Heuvel, Henricus J. C. M. Sterenborg, H. A. Martino Neumann, Ellen R. M. De Haas and Dominic J. Robinson

Photochem & Photobiology, 2010, 86, 1140
DOI: 10.1111/j.1751-1097.2010.00760.x

Is a single day patient friendly methyl aminolevulinate photodynamic therapy illumination scheme for superficial basal cell carcinoma feasible? A randomized multicenter pilot trial

K. P. Nguyen, G. J. Knuiman, W. A. M. Blokx, L. Hoogedoorn, T. Smits and M. J. P. Gerritsen

Journal of Dermatological Treatment, 2019, 30, 194
DOI: 10.1080/09546634.2018.1484558

Increased number of fractionated irradiation sessions does not improve the cellular response to methyl aminolevulinate-mediated photodynamic therapy

Calin Mihaela Antonina, Calin Marian Romeo, Petrescu Emil and Neagu Monica

Photodiagnosis and Photodynamic Therapy, 2013, 10, 526
DOI: 10.1016/j.pdpdt.2013.04.006

Light Fractionation Significantly Increases the Efficacy of Photodynamic Therapy Using BF-200 ALA in Normal Mouse Skin

Henriëtte S. de Bruijn, Sander Brooks, Angélique van der Ploeg-van den Heuvel, Timo L. M. ten Hagen, Ellen R. M. de Haas, Dominic J. Robinson and Adelaide Almeida

PLoS ONE, 2016, 11, e0148850
DOI: 10.1371/journal.pone.0148850

Advances in Photodynamic Therapy Dosimetry*

Bu-Hong LI, Shu-Sen XIE, Zheng HUANG and Brian C WILSON

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2009, 2009, 676
DOI: 10.3724/SP.J.1206.2008.00746

Topical hexylaminolevulinate and aminolevulinic acid photodynamic therapy: Complete arteriole vasoconstriction occurs frequently and depends on protoporphyrin IX concentration in vessel wall

T.A. Middelburg, H.S. de Bruijn, L. Tettero, A. van der Ploeg van den Heuvel, H.A.M. Neumann, E.R.M. de Haas and D.J. Robinson

Journal of Photochemistry and Photobiology B: Biology, 2013, 126, 26
DOI: 10.1016/j.jphotobiol.2013.06.014

Topical Photodynamic Therapy Using Different Porphyrin Precursors Leads to Differences in Vascular Photosensitization and Vascular Damage in Normal Mouse Skin

Tom A. Middelburg, Hannah C. de Vijlder, Henriette S. de Bruijn, Angélique van der Ploeg‐van den Heuvel, H. A. Martino Neumann, Ellen R. M. de Haas and Dominic J. Robinson

Photochem & Photobiology, 2014, 90, 896
DOI: 10.1111/php.12271

Treatment of superficial basal cell carcinoma by topical photodynamic therapy with fractionated 5-aminolaevulinic acid 20% vs. two-stage topical methyl aminolaevulinate: results of a randomized controlled trial

J.P.H.M. Kessels, H. Kreukels, P.J. Nelemans, M.H. Roozeboom, H. van Pelt, K. Mosterd, E.R.M. de Haas and N.W.J. Kelleners-Smeets

Br J Dermatol, 2018, 178, 1056
DOI: 10.1111/bjd.15967

In Vitro Low-Fluence Photodynamic Therapy Parameter Screening Using 3D Tumor Spheroids Shows that Fractionated Light Treatments Enhance Phototoxicity

Jose R. Aguilar Cosme, Dan C. Gagui, Nicola H. Green, Helen E. Bryant and Frederik Claeyssens

ACS Biomater. Sci. Eng., 2021, 7, 5078
DOI: 10.1021/acsbiomaterials.1c00690

Adjunctive treatment of keloids: comparison of photodynamic therapy with brachytherapy

Harie Basdew, Robert Mehilal, Abrahim Al-Mamgani, Peter van Rooij, Anand Bhawanie, Henricus J. C. M. Sterenborg, Rudi Tjong Joe Wai, Marc Mureau, Dominic J. Robinson and Peter C. Levendag

Eur J Plast Surg, 2013, 36, 289
DOI: 10.1007/s00238-012-0794-z

Optimization of Photodynamic Therapy in Dermatology: The Role of Light Fractionation

Luis Alonso-Mtz de Salinas, Emilio Garcia-Mouronte, Jorge Naharro-Rodriguez, Luis Alfonso Perez-Gonzalez and Montserrat Fernández-Guarino

IJMS, 2025, 26, 8054
DOI: 10.3390/ijms26168054

Fractionated aminolevulinic acid–photodynamic therapy provides additional evidence for the use of PDT for non‐melanoma skin cancer

ERM De Haas, HC De Vijlder, HJCM Sterenborg, HAM Neumann and DJ Robinson

Acad Dermatol Venereol, 2008, 22, 426
DOI: 10.1111/j.1468-3083.2007.02445.x

Two-fold illumination in topical 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) for superficial basal cell carcinoma (sBCC): A retrospective case series and cohort study

Janneke Kessels, Jolanda Hendriks, Patty Nelemans, Klara Mosterd and Nicole Kelleners-Smeets

Journal of the American Academy of Dermatology, 2016, 74, 899
DOI: 10.1016/j.jaad.2015.12.009

NF‐κB is Not Directly Responsible for Photoresistance Induced by Fractionated Light Delivery in HT‐29 Colon Adenocarcinoma Cells

Lucia Kuliková, Jaromír Mikeš, Martina Hýžďalová, Giuseppe Palumbo and Peter Fedoročko

Photochem & Photobiology, 2010, 86, 1285
DOI: 10.1111/j.1751-1097.2010.00788.x

Single vs. fractionated photodynamic therapy for face and scalp actinic keratoses: a randomized, intraindividual comparison trial with 12‐month follow‐up

E. Sotiriou, Z. Apalla, E. Chovarda, C. Goussi, A. Trigoni and D. Ioannides

Acad Dermatol Venereol, 2012, 26, 36
DOI: 10.1111/j.1468-3083.2011.04003.x

Microscopic localisation of protoporphyrin IX in normal mouse skin after topical application of 5-aminolevulinic acid or methyl 5-aminolevulinate

Henriëtte S. de Bruijn, Carel Meijers, Angélique van der Ploeg – van den Heuvel, Henricus J.C.M. Sterenborg and Dominic J. Robinson

Journal of Photochemistry and Photobiology B: Biology, 2008, 92, 91
DOI: 10.1016/j.jphotobiol.2008.05.005

The effect of light fractionation with a 2-h dark interval on the efficacy of topical hexyl-aminolevulinate photodynamic therapy in normal mouse skin

T.A. Middelburg, H.S. de Bruijn, A. van der Ploeg-van den Heuvel, H.A.M. Neumann and D.J. Robinson

Photodiagnosis and Photodynamic Therapy, 2013, 10, 703
DOI: 10.1016/j.pdpdt.2013.09.002