Issue 19, 2024

Design and preparation of fluorescent covalent organic frameworks for biological sensing

Abstract

Covalent organic frameworks (COFs) are a new class of functional solids featuring several fantastic structural characteristics, including a great diversity of building units and cross-linking patterns, precise integration of building blocks, and adjustable topology of porous architecture. In addition to the above features, some COF samples are constructed with high-density conjugated fragments, which have unique potential advantages in fluorescence imaging, and thus may have great potential applications in bioimaging. Herein, this article summarizes the recent progress in the design and preparation of fluorescent covalent organic frameworks. We investigate the systemic correlation between the structural qualities of COF networks and biological sensors. Finally, the significant advantages, major challenges, and future opportunities of fluorescent covalent organic frameworks are discussed for the development of next-generation porous materials for sensing applications.

Graphical abstract: Design and preparation of fluorescent covalent organic frameworks for biological sensing

Article information

Article type
Feature Article
Submitted
12 Հնվ 2024
Accepted
01 Փտվ 2024
First published
05 Փտվ 2024

Chem. Commun., 2024,60, 2605-2612

Design and preparation of fluorescent covalent organic frameworks for biological sensing

Y. Yang, C. Zhang, D. Cao, Y. Song, S. Chen, Y. Song, F. Wang, G. Wang and Y. Yuan, Chem. Commun., 2024, 60, 2605 DOI: 10.1039/D4CC00167B

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