Issue 35, 2021

The biology and total syntheses of bisbenzylisoquinoline alkaloids

Abstract

This mini-review provides a concise overview of the biosynthetic pathway and pharmacology of bisbenzylisoquinoline alkaloid (bisBIA) natural products. Additional emphasis is given to the methodologies in the total syntheses of both simpler acyclic diaryl ether dimers and their macrocyclic counterparts bearing two diaryl ether linkages.

Graphical abstract: The biology and total syntheses of bisbenzylisoquinoline alkaloids

Article information

Article type
Review Article
Submitted
26 Ապր 2021
Accepted
21 Հլս 2021
First published
17 Օգս 2021

Org. Biomol. Chem., 2021,19, 7535-7543

The biology and total syntheses of bisbenzylisoquinoline alkaloids

V. K. Nguyen and Kevin. G. M. Kou, Org. Biomol. Chem., 2021, 19, 7535 DOI: 10.1039/D1OB00812A

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