An electrochemically driven C–S radical–radical cross-coupling reaction between benzyl halides and disulfides for the synthesis of benzylic thioethers has been developed under environmentally friendly and mild conditions.
An efficient electrocatalytic method generates unstable radical anions under mild conditions, avoiding dangerous organolithium reagents. Achieves metal-free alkene homo-/cross-coupling without external oxidants/reductants in good yields.
This study explores the application of modified cysteine in oligopeptides to overcome challenges in amino acid residue modification, with a focus on cysteine.
A variety of 1,2,4-benzotriazines and benzotriazoles are conveniently and divergently synthesized via selective N–N or N–S bond cleavage of 1-trifluoromethyl benzotriazoles under different basic conditions.
A phosphine-mediated deoxygenative [3 + 2] cycloaddition reaction for oxazole synthesis via electrochemical anodic oxidation is herein reported.