Construction of chlorogenic acid nanoparticles for effective alleviation of ulcerative colitis

Shumeng Hu, Runan Zhao, Tao Chen, Xuesong Chi, Yangjing Li, Di Wu, Beiwei Zhu and Jiangning Hu

Food Funct., 2024, 15, 9085
DOI: 10.1039/D4FO02122C

The effect of microenvironmental viscosity on the emergence of colon cancer cell resistance to doxorubicin

Tianjiao Zeng, Chengyu Lu, Man Wang, Huajian Chen, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang and Guoping Chen

J. Mater. Chem. B, 2025, 13, 2180
DOI: 10.1039/D4TB02334J

Chlorogenic acid and intestinal health: mechanistic insights and therapeutic applications

Jinzhao Xu, Xiao Zhao, Shuo Yang, Mengqi Tang, Runan Zhao and Shumeng Hu

Food Funct., 2025, 16, 4257
DOI: 10.1039/D5FO00853K

Advances in novel drug delivery systems: a focus on nanoparticles and mucoadhesive technologies

Ravi Sangavi, Sulekha Khute and Paranthaman Subash

Drug Development and Industrial Pharmacy, 2025, 51, 1673
DOI: 10.1080/03639045.2025.2564364

Nanotechnology-based drug delivery system for targeted therapy of ulcerative colitis from traditional Chinese medicine: A review

Chengcheng Gao, Zerun Yang, Ruirui Song, Huagang Sheng and Liqiao Zhu

International Journal of Pharmaceutics, 2025, 673, 125375
DOI: 10.1016/j.ijpharm.2025.125375

Machine Learning‐Assisted High‐Throughput Screening of Nanozymes for Ulcerative Colitis

Xianguang Zhao, Yixin Yu, Xudong Xu, Ziqi Zhang, Zhen Chen, Yubo Gao, Liang Zhong, Jiajie Chen, Jiaxin Huang, Jie Qin, Qingyun Zhang, Xuemei Tang, Dongqin Yang and Zhiling Zhu

Advanced Materials, 2025, 37
DOI: 10.1002/adma.202417536

Tuning gut microbiota by advanced nanotechnology

Yue Qi, Yueyi Wang, Xiaofei Wang, Hao Zheng and Yuan Lu

Mater. Futures, 2025, 4, 012302
DOI: 10.1088/2752-5724/ada62b

Selective detection of inflammatory bowel disease in spectral CT imaging utilizing hyaluronic acid‑neodymium vanadate nanoparticles

Qiuyu Meng, Wenqian Ru, Xiaoling Che, Chai Yang, Xinhang Guo, Yuankai Gong, Zhongyuan Zhang, Ji Wu, Chunmei Yang and Lu Yang

International Journal of Biological Macromolecules, 2026, 355, 151480
DOI: 10.1016/j.ijbiomac.2026.151480

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim and Han Young Kim

Adv Funct Materials, 2025
DOI: 10.1002/adfm.202516976

The Construction Strategy of Curcumin Nanomedicine Delivery System and Its Application in the Treatment of Ulcerative Colitis

Hang Ning, Xinyu Huang, Xiaoyuan Lin, Qifang Sun, Yuchen Zheng, Na Deng and Yin Xu

IJN, 2025, Volume 20, 15135
DOI: 10.2147/IJN.S573966

Targeting mitochondrial dysfunction through nanomedicine: a new avenue for inflammatory bowel disease therapy

Mohammad Samimi Tanoorjeh, Hossein Shahdadi Sardou, Sara Feizollahi, Prashant Kesharwani, Mohammadreza Abbaspour and Amirhossein Sahebkar

Microchemical Journal, 2026, 224, 117838
DOI: 10.1016/j.microc.2026.117838

A New Paradigm for Precision Drug Delivery in Inflammatory Bowel Disease: Effective Transfer, Enhanced Retention, and Pathology‐Targeting Treatment via Biomaterials and Engineered Platforms

Ruoyi Gan, Enqi Ni, Guanyue Li and Wei Chen

MedComm – Biomaterials and Applications, 2025, 4
DOI: 10.1002/mba2.70022

Dynamic polysaccharide-based organic nanocomposite hydrogel precisely mediates oral targeted therapy for colorectal cancer

Xinyang Chen, Nuo Li, Huazheng Cheng, Ying Zhang, Ruiting Pan, Qin Shen and Guoqing Yan

Carbohydrate Polymers, 2026, 380, 125138
DOI: 10.1016/j.carbpol.2026.125138

Research Progress on Chinese Herbal Medicine in Alleviating Colitis by Regulating Microecology

双琦罗

BP, 2024, 14, 116
DOI: 10.12677/bp.2024.142015

Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends

Hong-Yu Jiang, Bo Shao, Hong-Da Wang, Wen-Qi Zhao, Shao-Hua Ren, Yi-Ni Xu, Tong Liu, Cheng-Lu Sun, Yi-Yi Xiao, Yi-Cheng Li, Qiang Chen, Peng-Yu Zhao, Guang-Mei Yang, Xu Liu, Yu-Fan Ren and Hao Wang

Front. Pharmacol., 2025, 15
DOI: 10.3389/fphar.2024.1523052

pH-responsive Oral liposomal delivery of hydrogen sulfide donor GYY4137 enables colon-targeted therapy for inflammatory bowel disease

Chiwoo Oh, Jee-Eun Hwang, Hyunjoon Yim, Haena Park, Seo-young Kim, Jae Kyoo Lee and Hyung-Jun Im

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03753-9

Engineering probiotics for inflammatory bowel disease: Strategies and perspectives

Chongzhi Ye, Lishan Wang, Yunan Gao, Zhiai Rui, Qing He, Yujing Zhang, Hongwei Si, Pei Pei and Wanni Wang

Chinese Chemical Letters, 2025, 112219
DOI: 10.1016/j.cclet.2025.112219

Nanotherapeutic Approaches for Ulcerative Colitis: Frontier Research and Clinical Application

汝冰刘

ACM, 2025, 15, 338
DOI: 10.12677/acm.2025.1561731

Isopimpinellin: A Promising Treatment for Colitis‐Related Colorectal Cancer That Targets ALOX5‐Mediated Macrophage Polarization

Min Zhan, Qin Yi, Liang Yu, Qiankun Li, Murong Jiang, Dongsheng Wu, Mintao Jian, Hui Cao and Donghua Bin

Phytotherapy Research, 2025, 39, 5249
DOI: 10.1002/ptr.70065

Beta-Sitosterol-Conjugated Sinapic Acid-Engineered Nanoliposome: Biomucoadhesive and Enzyme-Responsive Targeted Oral Therapy in Ulcerative Colitis

Kanika, Ajay Kumar, Anas Ahmad, Rahul, Bhuvnesh Kumar, Shubham Mahajan, Aneesh Ali, Jattin kumar, Nemat Ali, Umashanker Navik, Suhel Parvez and Rehan Khan

ACS Appl. Mater. Interfaces, 2025, 17, 27839
DOI: 10.1021/acsami.5c02190

Pathophysiology of IBD as a Key Strategy for Polymeric Nanoparticle Development

Elena Gardey, Johannes C. Brendel and Andreas Stallmach

Advanced Therapeutics, 2025, 8
DOI: 10.1002/adtp.202400439

Sustained release of 5-aminosalicylic acid from azoreductase-responsive polymeric prodrugs for prolonged colon-targeted colitis therapy

Sicheng Tang, Wenchao Wang, Yijian Wang, Yuhan Gao, Keke Dai, Wenjing Zhang, Xudong Wu, Xiaodie Yuan, Chaofan Jin, Xingjie Zan, Limeng Zhu and Wujun Geng

J Nanobiotechnol, 2024, 22
DOI: 10.1186/s12951-024-02724-w

Application of aggregation-induced emission materials in gastrointestinal diseases

Yi-Rong Li, Gang Wang, Wen-Ting He and Tao Liu

World J Gastroenterol, 2025, 31
DOI: 10.3748/wjg.v31.i16.105378

Leveraging dietary fiber’s natural physiology: from dietary insights to nanoscale IBD intervention

Peilong Liao, Jian Chen, Yanbo Wang and Huan Li

Critical Reviews in Food Science and Nutrition, 2026, 66, 1867
DOI: 10.1080/10408398.2025.2556479

Oral delivery of ultra-small zwitterionic nanoparticles to overcome mucus and epithelial barriers for macrophage modulation and colitis therapy

Changshun Zhao, Suchen Wen, Rui Xu, Ke Wang, Yinan Zhong, Dechun Huang, Bingbing Zhao and Wei Chen

Acta Biomaterialia, 2025, 196, 399
DOI: 10.1016/j.actbio.2025.02.039

Selective Nanoparticulate Systems for Drug Delivery in Inflammatory Bowel Disease

Alberta Ribeiro and Rute Nunes

Pharmaceutics, 2025, 18, 55
DOI: 10.3390/pharmaceutics18010055

Colon-targeted microbiota-modulating nanoparticles amplify azathioprine efficacy via gut microbiota axis remodeling in inflammatory bowel disease

Jingjing Zhang, Yanni Zhang, Xiao Lu, Jiaqi Han, Luquan Wang, Yubin He, Siyao Jin, Yana Li, Xiangyu Ma, Hao Bing, Dong Mei and Libo Zhao

J Nanobiotechnol, 2026, 24
DOI: 10.1186/s12951-026-04136-4

Thermo-responsive in situ hydrogel enables superior rectal administration and local efficacy of 5-ASA in inflammatory bowel disease

Elena Giuliano, Angela Costagliola di Polidoro, Agnese Gagliardi, Domenico Sorrentino, Emanuela Longo, Sandra Albanese, Francesco Napolitano, Valeria Gaetano, Antonella Zannetti and Donato Cosco

Biomaterials Advances, 2026, 183, 214762
DOI: 10.1016/j.bioadv.2026.214762

Recent advances in polymer-based nanoformulations for enhancing oral drug delivery in diabetes

Sourbh Suren Garg, Rajlaxmi Dey, Atulika Sharma and Jeena Gupta

Journal of Drug Delivery Science and Technology, 2024, 100, 106119
DOI: 10.1016/j.jddst.2024.106119

Advanced oral drug delivery systems for gastrointestinal targeted delivery: the design principles and foundations

Yafei Zhang, Yiran Wang, Yao Lu, Heng Quan, Yuqi Wang, Sijia Song and Huiyuan Guo

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03479-8

RONS clearing Te Pt @ sodium carboxymethyl cellulose nanozymes for chronic enteritis therapy

Xinyan Hu, Gongxin Zhang, Lida Tang, Yun Li, Yayao Wang, Dongxu Cao, Zhide Guo and Xiaolan Chen

International Journal of Biological Macromolecules, 2025, 319, 145792
DOI: 10.1016/j.ijbiomac.2025.145792

Artemisia argyi polyphenols Attenuates DSS-induced colitis in mice by regulating the structural composition of gut microbiota

Huaqiang Zhang, Zhonghua Hao, Ruya Zhang, Jiang Tong, Xiaoke Wang, Jingjing Liu, Yingkui Gao, Xuefang Wang, Qing Su, Haojie Wen, Yi Fan, Fang Liu, Xiao Li, Chao Tong and Xuebing Wang

Phytomedicine, 2024, 132, 155897
DOI: 10.1016/j.phymed.2024.155897

Acid-tolerant and hypoxia-responsive drug delivery system based on sulphobetaine-modified azocalix[4]arene for treating ulcerative colitis

Jing Liu, Juan-Juan Li, Hai-Qing Li, Meiqi Yang, Kai Zhang, Fangqian Yin, Yanbin Ren, Mengqiong Ming, Dong-Sheng Guo and Ke-Rang Wang

Nano Today, 2025, 64, 102801
DOI: 10.1016/j.nantod.2025.102801