Treatment of diabetic wounds using dissolvable microneedle patches co-delivering levofloxacin and lidocaine

Arifur Rahman Nibir, Jamila Akther, Ferdous-Ul-Haque Joy, Tahmina Foyez, Md. Borhan Uddin and Shazid Md. Sharker

J. Mater. Chem. B, 2026, 14, 3693
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Conditioned medium of engineering macrophages combined with soluble microneedles promote diabetic wound healing

HongYu Wang, BaoHua Wei, Hasi WuLan, Bin Qu, HuiLong Li, Jing Ren, Yan Han, LingLi Guo and Zhengwei Huang

PLoS ONE, 2025, 20, e0316398
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A biphasic drug-releasing microneedle with ROS scavenging and angiogenesis for the treatment of diabetic ulcers

Xinyue He, Lianghong Peng, Liming Zhou, Huiling Liu, Yifan Hao, Yuhan Li, Zijin lv, Baohui Zeng, Xinmin Guo and Rui Guo

Acta Biomaterialia, 2024, 189, 270
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Redox-active microneedles for disease management

Brian Youden, Andrew Carrier, Naizhen Yu, Claudia Hodson, Kehinde Oni, Fathimath Chirathodi, Dongchang Yang, Mark Servos, Ken Oakes, Yongli Chen, Runqing Jiang, Ryan F. Donnelly and Xu Zhang

Journal of Controlled Release, 2026, 392, 114717
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Metallic nanoparticles in diabetes mellitus: Mechanistic insights and therapeutic perspectives

Preeti Pal and Ashutosh Pareek

Journal of Trace Elements in Medicine and Biology, 2026, 94, 127833
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Microneedles’ Device: Design, Fabrication, and Applications

Cristiana Oliveira, José A. Teixeira, Nelson Oliveira, Sónia Ferreira and Cláudia M. Botelho

Macromol, 2024, 4, 320
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The advances in zwitterionic materials and their biomedical applications

Wei He, Jiayao Wen, Qiaoying Hu, Yanmin Yi, Zhijian Wei, Xiaoye Yang, Guangxi Zhai, Feng Li and Lei Ye

International Materials Reviews, 2025, 70, 301
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Research Progress on the Application of Novel Wound Healing Dressings in Different Stages of Wound Healing

Lihong Wang, Xinying Lu, Yikun Wang, Lina Sun, Xiaoyu Fan, Xinran Wang and Jie Bai

Pharmaceutics, 2025, 17, 976
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NIR-II-triggered PTT/ TDT synergistic treatment system: Highly effective hemostatic and antibacterial, promotes deep wound healing

Yumeng Zhang, Qingyan Kang, Mengya Sun, Suqing Shi, Chang Yang, Xudong Liu, Linghan Xiao, Wei Zhu and Yujing Liu

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2025, 727, 138476
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Highly printable and multifunctional cell-laden collagen-based bioinks for precise DLP bioprinting and rapid diabetic wound regeneration

Caihong Fu, Guangyu Liu, Yirui Fan, Lang Xiao, Wenhua Li, Xinyu Tian and Jianxi Xiao

Materials Today Bio, 2025, 32, 101908
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Antimicrobial microneedles: Advances, mechanisms, and applications in combating bacterial infections

Huishan Zheng, Changzhou Jin, Baozhu Feng, Meilian Ning, Ziyan Cai, Qiulong Zhang and Jianmin Chen

International Journal of Pharmaceutics, 2025, 683, 126028
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The Unprecedented Biodegradable Polyzwitterion: A Removal‐Free Patch for Accelerating Infected Diabetic Wound Healing

Zhuoya Wang, Danyang Chen, Hongying Wang, Siyu Bao, Liping Lang, Chunyan Cui, Haotian Song, Jianhai Yang and Wenguang Liu

Advanced Materials, 2024, 36
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Bilayer Microneedle Patch Loaded with Keratin-Based Hydrogen Sulfide Donor and Ciprofloxacin for Diabetic Wound Healing

Fengni Liu, Haiping Hu, Yu Sun, Zhaoyan Ge, Jian Shen and Jiang Yuan

Langmuir, 2025, 41, 23965
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Revolutionizing diabetic wound healing: The power of microneedles

Chun Liang, Ren Wang, Tian He, Dongsheng Chen, Guangliang Zhang, Xiangye Yin, Hongyu Wang, Jiale Xie, Yujing Li and Youbai Chen

Chinese Journal of Plastic and Reconstructive Surgery, 2023, 5, 185
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Nonfouling Core–Shell Microneedle for Sequential and Sustained Drug Release: Enhancing Synergistic Photothermal Chemotherapy in Melanoma Treatment

Dongyu Huang, Qingyu Yu, Kaiyue Yang, Xiuqiang Li, Chenlu Huang, Xinyu Yang, Chaoxiong Wu, Cheng Cao, Linhua Zhang, Dunwan Zhu and Junjie Li

ACS Appl. Bio Mater., 2025, 8, 3356
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A Multifunctional Hydrogel Fabricated by Direct Self-Assembly of Natural Herbal Small Molecule Mangiferin for Treating Diabetic Wounds

Mengke Hao, Simin Wei, Siqi Su, Zhishu Tang and Yinghui Wang

ACS Appl. Mater. Interfaces, 2024, 16, 24221
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Applications and prospects of biomaterials in diabetes management

Wenhe Guan and Liang Zhang

Front. Bioeng. Biotechnol., 2025, 13
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Rational Design and Adaptive Transdermal Cargo Delivery of Microneedle in Dermatologic Therapeutics

Yan Shi, Jiaxuan Zhao, Jinrui Li, Ziye Lin, Lu Liu and Ming Kong

Small, 2025, 21
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Smart drug delivery and responsive microneedles for wound healing

Meixuan Liu, Jing Jiang, Yiran Wang, Huan Liu, Yiping Lu and Xingang Wang

Materials Today Bio, 2024, 29, 101321
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Integration of metformin-loaded MIL-100(Fe) into hydrogel microneedles for prolonged regulation of blood glucose levels

Mingjia Feng, Yan Li, Yanfang Sun, Tianqi Liu, Khaydar E Yunusov and Guohua Jiang

Biomed. Phys. Eng. Express, 2024, 10, 045004
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Morphology design of polymer microneedle arrays: Key factors from the application perspective

Baoling Jia, Tiandong Xia, Xiaohui Wang, Yangtao Xu and Zhenyu Guo

Journal of Drug Delivery Science and Technology, 2023, 88, 104883
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A lipoic acid supramolecular polymer-based hydrogel with self-regulating ROS, reduced blood sugar, and antibacterial ability for improved diabetic wound healing

Ling Wang, Guojuan Fan, Lijie Zhu, Yuzhong Zhang, Xiaoxia Wang, Jiamin Qin, Keliang Lu, Jinxing Hu and Jinlong Ma

Journal of Science: Advanced Materials and Devices, 2024, 9, 100677
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Metal ion formulations for diabetic wound healing: Mechanisms and therapeutic potential

Yuhe Dai, Qianbo Zhang, Rifang Gu, Jitao Chen, Penghui Ye, Huan Zhu, Ming Tang and Xuqiang Nie

International Journal of Pharmaceutics, 2024, 667, 124889
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Double-layered microneedle patch for melanoma chemo/photothermal co‑therapy and wound healing

Yisheng Hu, Ya Wang, Yuqing Cai, Xiaodong Xu, Liping Zhao and Jing Zhang

Applied Materials Today, 2025, 44, 102708
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Antibacterial Agents Employed in Microneedles for the Management of Diabetic Ulcers: Review

Ikhlas Jarrar

Palestinian Medical and Pharmaceutical Journal, 2025, 10, 317
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Injectable Microparticle-containing hydrogel with controlled release of bioactive molecules for facial rejuvenation

Semi Lee, Seung-Woon Baek, Da-Seul Kim, So-Yeon Park, Jun Hyuk Kim, Ji-Won Jung, Jun-Kyu Lee, Gi-Min Park, Chun Gwon Park and Dong Keun Han

Materials Today Bio, 2024, 24, 100890
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Novel microneedle platforms for the treatment of wounds by drug delivery: A review

Heng An, Zhen Gu, Zhe Huang, Tong Huo, Yongxiang Xu, Yaozhong Dong and Yongqiang Wen

Colloids and Surfaces B: Biointerfaces, 2024, 233, 113636
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Wirelessly Powered Drug-Free and Anti-Infective Smart Bandage for Chronic Wound Care

Irfan Ullah, Mahmoud Wagih, Yixuan Sun, Yi Li, Kata Hajdu, Rémi Courson, Catherine Dreanno, Enora Prado, Abiodun Komolafe, Nick R. Harris, Neil M. White and Steve Beeby

IEEE Trans. Biomed. Circuits Syst., 2023, 17, 900
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Green synthesis of chitosan–silver nanoparticles using Lannea coromandelica: A synergistic in vitro and in vivo approach for accelerated wound healing in BALB/c mice

Mydhili Govindarasu, Manju Vaiyapuri and Muthu Thiruvengadam

Biocatalysis and Agricultural Biotechnology, 2025, 70, 103876
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Microneedles in diabetic wound care: multifunctional solutions for enhanced healing

Xichao Jian, Yaping Deng, Shune Xiao, Fang Qi and Chengliang Deng

Burns & Trauma, 2025, 13
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Functional biomacromolecules-based microneedle patch for the treatment of diabetic wound

Chenyu Zhao, Zhaoqi Wu, Boyue Pan, Ruihan Zhang, Avin Golestani, Ziyi Feng, Yi Ge and Huazhe Yang

International Journal of Biological Macromolecules, 2024, 267, 131650
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Asiaticoside-Loaded Multifunctional Bioscaffolds for Enhanced Hyperglycemic Wound Healing

Raniya Razif, Nur Izzah Md Fadilah, Haslina Ahmad, Daniel Looi Qi Hao, Manira Maarof and Mh Busra Fauzi

Biomedicines, 2025, 13, 277
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Microneedles-photothermal therapy synergy in biomedicine: Innovations and applications

Dan He, Tian Liang, Yongjin Zhong, Keng-Fu Lan, Siqi Ye, Yingying Wu and Anchun Mo

Colloids and Surfaces B: Biointerfaces, 2026, 259, 115303
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