Initial encounter complex formation with nucleophiles enhances ring strain in azaphosphiridines thus promoting P–C bond cleavage.
An efficient Ir-catalyzed multicomponent photoredox radical addition/C–H activation/annulation reaction for the synthesis of “CF2”-functionalized cyclic phosphinimides is reported.
1,3-Dipolar cycloadditions allow the syntheses of a plethora of (poly)-azaphosphole derivatives that allow the access to a large range of phosphorous-containing ring systems.
A highly reactive, transiently formed terminal phosphinidene complex reacts with triethylamine to form a primary phosphane complex, eventually. The dehydrogenation is explained by a detailed, DFT-based mechanistic proposal.
Synthetic methods include cyclizations for construction of P–O, O–C, P–C, and C–C bonds, annulations involving [4+2], [5+1], and [3+3] fashions, cycloadditions, ring contractions and expansions.