Convenient tumor 3D spheroid arrays manufacturing via acoustic excited bubbles for in situ drug screening

Jingjing Zheng, Xuejia Hu, Xiaoqi Gao, Yantong Liu, Shukun Zhao, Longfei Chen, Guoqing He, Jingwei Zhang, Lei Wei and Yi Yang

Lab Chip, 2023, 23, 1593
DOI: 10.1039/D2LC00973K

Acoustic quasi-periodic bioassembly based diverse stem cell arrangements for differentiation guidance

Xiaoqi Gao, Xuejia Hu, Dongyong Yang, Qinghao Hu, Jingjing Zheng, Shukun Zhao, Chengliang Zhu, Xuan Xiao and Yi Yang

Lab Chip, 2023, 23, 4413
DOI: 10.1039/D3LC00448A

Microfluidic-based in vitro thrombosis model for studying microplastics toxicity

Longfei Chen, Yajing Zheng, Yantong Liu, Pengfu Tian, Le Yu, Long Bai, Fuling Zhou, Yi Yang, Yanxiang Cheng, Fubing Wang, Li Zheng, Fenghua Jiang and Yimin Zhu

Lab Chip, 2022, 22, 1344
DOI: 10.1039/D1LC00989C

Intolerance of profligacy: an aptamer concentration gradient-tailored unicellular array for high-throughput biologics-mediated phenotyping

Xuan Zhang, Ya-Nan Zhao, Xing Wei, Xue Men, Cheng-Xin Wu, Jun-Jie Bai, Ting Yang, Ming-Li Chen and Jian-Hua Wang

Lab Chip, 2022, 22, 4238
DOI: 10.1039/D2LC00729K

On-demand liquid microlens arrays by non-contact relocation of inhomogeneous fluids in acoustic fields

Xiaoqi Gao, Xuejia Hu, Jingjing Zheng, Qinghao Hu, Shukun Zhao, Longfei Chen and Yi Yang

Lab Chip, 2022, 22, 3942
DOI: 10.1039/D2LC00603K

An ultrasonic sweeper with micro-/nano-concentration, decorating, transmedium extraction, and localized cleaning functions

Qingyang Liu, Qiang Tang and Junhui Hu

Review of Scientific Instruments, 2023, 94
DOI: 10.1063/5.0141283

An optofluidic system for the concentration gradient screening of oocyte protection drugs

Dongyong Yang, Qinghao Hu, Shukun Zhao, Xuejia Hu, Xiaoqi Gao, Fangfang Dai, Yajing Zheng, Yi Yang and Yanxiang Cheng

Talanta, 2024, 278, 126472
DOI: 10.1016/j.talanta.2024.126472

Physical Intracellular Delivery Based on Microfluidic Technology

Chong Ji, Yuanyuan Song, Zhiwei Fan, Luoming Liu, Ying Sun, Ruitong Yang, Chunlei Ma, Yuxiang Cai, Dongyang Miao, Chaobo Huang and Ranhua Xiong

Small, 2025, 21
DOI: 10.1002/smll.202504048

Effects of Side Profile on Acoustic Streaming by Oscillating Microstructures in Channel

Lin Lin, Haojie Dang, Rongxin Zhu, Ying Liu and Hui You

Micromachines, 2022, 13, 1439
DOI: 10.3390/mi13091439

Acoustic Controllable Spatiotemporal Cell Micro-oscillation for Noninvasive Intracellular Drug Delivery

Xiaoqi Gao, Dayang Li, Shukun Zhao, Dongyong Yang, Qian Wu, Sen-Sen Li, Liyuan Zhang, Lu-Jian Chen, Yi Yang and Xuejia Hu

Anal. Chem., 2024, 96, 14998
DOI: 10.1021/acs.analchem.4c03187

Ultrasound-Enabled Nanomedicine for Tumor Theranostics

Kairui Liu, Boyuan Jing, Jun Kang, Lei Han and Jin Chang

Engineering, 2025, 46, 101
DOI: 10.1016/j.eng.2024.01.030

Recent advances in microfluidic single-cell analysis and its applications in drug development

Yufeng Jiao, Liyang Gao, Yaru Ji and Wu Liu

TrAC Trends in Analytical Chemistry, 2022, 157, 116796
DOI: 10.1016/j.trac.2022.116796

Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review

Aleksei P. Iakovlev, Alexander S. Erofeev and Petr V. Gorelkin

Biosensors, 2022, 12, 956
DOI: 10.3390/bios12110956

Nanoplasmonic Affinity Analysis System for Molecular Screening Based on Bright‐Field Imaging

Mingqian Chen, Hongli Fan, Wen Li, Jingyan Ruan, Yihui Yang, Cuixuan Mao, Rui Li, Gang L. Liu and Wenjun Hu

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202314481

A Nano‐Electroporation‐DNA Tensioner Platform Enhances Intracellular Delivery and Mechanical Analysis Toward Rapid Drug Assessment

Xinxin Hang, Zhaocun Huang, Shiqi He, Zhiying Wang, Zaizai Dong and Lingqian Chang

Small Methods, 2024, 8
DOI: 10.1002/smtd.202300915

Three-dimensional array of microbubbles sonoporation of cells in microfluidics

Guangyong Huang, Lin Lin, Quanhui Liu, Shixiong Wu, Jiapeng Chen, Rongxing Zhu, Hui You and Cuimin Sun

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1353333

A two-chip acoustofluidic microdroplet centrifugation platform for high-sensitivity detection of miRNA

Fahui Dong, Zhi Yu, Xiaoxia Yang, Jie Chen, Luoke Hu, Yong Wang and Jingang Han

Sensors and Actuators A: Physical, 2025, 392, 116718
DOI: 10.1016/j.sna.2025.116718

The Convergence of Artificial Intelligence and Microfluidics in Drug Research and Development

Du Qiao, Hongxia Li, Xue Zhang, Xuhui Chen, Jiang Zhang, Jianan Zou, Danyang Zhao, Weiping Zhu, Xuhong Qian and Honglin Li

Engineering, 2025
DOI: 10.1016/j.eng.2025.07.025

Acoustic-propelled micro/nanomotors and nanoparticles for biomedical research, diagnosis, and therapeutic applications

Guanyu Mu, Yu Qiao, Mingyang Sui, Kenneth T. V. Grattan, Huijuan Dong and Jie Zhao

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1276485

Microfluidics in High-Throughput Drug Screening: Organ-on-a-Chip and C. elegans-Based Innovations

Sunhee Yoon, Dilara Kilicarslan You, Uiechan Jeong, Mina Lee, Eunhye Kim, Tae-Joon Jeon and Sun Min Kim

Biosensors, 2024, 14, 55
DOI: 10.3390/bios14010055

Magnetically Actuated Hydrogel Stamping-Assisted Cellular Mechanical Analyzer for Stored Blood Quality Detection

Le Yu, Longfei Chen, Yantong Liu, Jiaomeng Zhu, Fang Wang, Linlu Ma, Kezhen Yi, Hui Xiao, Fuling Zhou, Fubing Wang, Long Bai, Yimin Zhu, Xuan Xiao and Yi Yang

ACS Sens., 2023, 8, 1183
DOI: 10.1021/acssensors.2c02507

Combining Ultrasound-Mediated Intracellular Delivery with Microfluidics in Various Applications

Guangyong Huang, Lin Lin, Shixiong Wu, Haojie Dang, Xuesong Cheng, Ying Liu and Hui You

BioChip J, 2024, 18, 22
DOI: 10.1007/s13206-023-00128-w

Heterogeneous Organohydrogel Toward Automated and Interference‐Free Gradient Feeding of Drugs in Cell Screening

Hongxiao Gao, Xizi Wan, Wu‐Yi Xiao, Yuemeng Yang, Jingwei Lu, Shihao Wu, Li‐Ping Xu and Shutao Wang

Advanced Science, 2024, 11
DOI: 10.1002/advs.202401720

Gradient hydrogels: From fabrication strategies, reinforcement mechanisms, to biomedical applications

Yufei Yong, Lianghao Jia, Hongrong Wu, Tao Xiang and Shaobing Zhou

Chemical Engineering Journal, 2025, 522, 167390
DOI: 10.1016/j.cej.2025.167390

Design and fabrication of novel microfluidic-based droplets for drug screening on a chronic myeloid leukemia cell line

Niloofar Jaafari, Amir Asri Kojabad, Rima Manafi Shabestari, Majid Safa and Jian Wu

PLoS ONE, 2025, 20, e0315803
DOI: 10.1371/journal.pone.0315803

Recent Advances of Organ-on-a-Chip in Cancer Modeling Research

Xingxing Liu, Qiuping Su, Xiaoyu Zhang, Wenjian Yang, Junhua Ning, Kangle Jia, Jinlan Xin, Huanling Li, Longfei Yu, Yuheng Liao and Diming Zhang

Biosensors, 2022, 12, 1045
DOI: 10.3390/bios12111045

The Shape Effect of Acoustic Micropillar Array Chips in Flexible Label-Free Separation of Cancer Cells

Lin Lin, Rongxing Zhu, Wang Li, Guoqiang Dong and Hui You

Micromachines, 2024, 15, 421
DOI: 10.3390/mi15040421

Lab-on-a-chip systems for cancer biomarker diagnosis

Canan Özyurt, İnci Uludağ, Bahar İnce and Mustafa Kemal Sezgintürk

Journal of Pharmaceutical and Biomedical Analysis, 2023, 226, 115266
DOI: 10.1016/j.jpba.2023.115266

An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening

Biao Wang, Bang-Shun He, Xiao-Lan Ruan, Jiang Zhu, Rui Hu, Jie Wang, Ying Li, Yun-Huang Yang and Mai-Li Liu

Military Med Res, 2022, 9
DOI: 10.1186/s40779-022-00409-9

On-demand transdermal drug delivery platform based on wearable acoustic microneedle array

Qian Wu, Chen Pan, Puhuan Shi, Lei Zou, Shiya Huang, Ningning Zhang, Sen-Sen Li, Qian Chen, Yi Yang, Lu-Jian Chen and Xuejia Hu

Chemical Engineering Journal, 2023, 477, 147124
DOI: 10.1016/j.cej.2023.147124

Microfluidic nanodevices for drug sensing and screening applications

Arnab Pal, Kuldeep Kaswan, Snigdha Roy Barman, Yu-Zih Lin, Jun-Hsuan Chung, Manish Kumar Sharma, Kuei-Lin Liu, Bo-Huan Chen, Chih-Cheng Wu, Sangmin Lee, Dongwhi Choi and Zong-Hong Lin

Biosensors and Bioelectronics, 2023, 219, 114783
DOI: 10.1016/j.bios.2022.114783