Issue 30, 2012
From the journal:

Organic & Biomolecular Chemistry

Amphiphilic α-helix mimetics based on a benzoylurea scaffold†‡

Sam Thompsona  and  Andrew D. Hamilton*a  

* Corresponding authors

a Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK
E-mail: andrew.hamilton@chem.ox.ac.uk
Tel: +44 (0)1865 270242

Abstract

The design and synthesis of amphiphilic benzoylurea α-helix mimetics is described. These conformationally constrained molecules allow for the correct angular and spatial projection of hydrophobic and hydrophilic groups and thus the reproduction of side-chains on both faces of an α-helix.

Graphical abstract: Amphiphilic α-helix mimetics based on a benzoylurea scaffold

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2OB25273B
Article type
Communication
Submitted
06 vlj 2012
Accepted
19 ožu 2012
First published
25 tra 2012

Org. Biomol. Chem., 2012,10, 5780-5782

Permissions

Request permissions

Amphiphilic α-helix mimetics based on a benzoylurea scaffold

S. Thompson and A. D. Hamilton, Org. Biomol. Chem., 2012, 10, 5780 DOI: 10.1039/C2OB25273B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements