Xu Yan, Wei Feng, Jiong Xu Ng, Jiaxin Li, Ying Liu, Bo Zhang, Pan-Lin Shao and Yu Zhao
Chem. Soc. Rev., 2025,54, 7966-8018
Abstract
This review aims to provide a thorough overview of recent advancements in the synthesis of chiral vicinal amino alcohols, with a particular focus on strategic developments over the past two decades.
Guoqi Huang, Yu Wu, Hegui Gong and Yunrong Chen
Org. Biomol. Chem., 2023,21, 6111-6114
Abstract
An economical route providing quick access to chiral vicinal amino alcohols bearing a symmetric β-sec-alkyl group was developed.
Pei-Jun Yang and Zhuo Chai
Org. Biomol. Chem., 2023,21, 465-478
Abstract
Over the past three decades, the catalytic enantioselective desymmetrization of meso-aziridines has evovled to be a ready synthetic toolkit for efficient construction of diverse useful nitrogen-containing molecules bearing contiguous stereocenters.
Padmanava Barik, Subhasmita Sahoo, Usharani Das and Santosh Kumar Nanda
Chem. Commun., 2025,61, 11581-11596
Abstract
The photocatalytic and electrocatalytic cross aza–pinacol coupling has been a potential method for the rapid access to amino alcohols in an eco-friendly manner.
Peilong Gu, Shuangshuang Wang, Xiangxiang Wen, Jinxin Tian, Chao Wang, Lili Zong and Choon-Hong Tan
Org. Chem. Front., 2024,11, 836-842
Abstract
Chiral cinchoninium catalysed permanganate dihydroxylation of enoates with different substitution types, including challenging tetrasubstituted ones, provides good yields of chiral vicinal diols in up to 98% ee.