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RSC Adv., 2025, 15, 10902
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Ion-incorporated titanium implants for staged regulation of antibacterial activity and immunoregulation-mediated osteogenesis

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Nanoscale, 2024, 16, 7167
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Methacryloylated chitosan hydrogel-mediated polyphenol-Ga/hUCMSC-Exo release platform: Possessing antibacterial, anti-inflammatory, and osteogenic capabilities

Hui Su, Fengzhen Jia, Zitong Tian, Xinyi Hu, Hao Yang, Jiamin Li, Pengde Han, Xiaojun Zhang, Xiong Zhang, Xiao Huang, Zongze Wu and Yong Huang

International Journal of Biological Macromolecules, 2025, 309, 142893
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Comprehensive Overview of Interface Strategies in Implant Osseointegration

Xiaoheng Lu, Yuhu Zhao, Xiaole Peng, Chengyao Lu, Zebin Wu, Hao Xu, Yi Qin, Yaozeng Xu, Qing Wang, Yuefeng Hao and Dechun Geng

Adv Funct Materials, 2025, 35
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Cross-talk between biometal ions and immune cells for bone repair

Shubo Liu, Zhengjie Lin, Wei Qiao, Bin Chen and Jie Shen

Engineered Regeneration, 2024, 5, 375
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The Role of HIF-1α in Bone Regeneration: A New Direction and Challenge in Bone Tissue Engineering

Jiaqian You, Manxuan Liu, Minghui Li, Shaobo Zhai, Sezhen Quni, Lu Zhang, Xiuyu Liu, Kewen Jia, Yidi Zhang and Yanmin Zhou

IJMS, 2023, 24, 8029
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Research progress of vascularization strategies of tissue-engineered bone

Nanning Lv, Zhangzhe Zhou, Mingzhuang Hou, Lihui Hong, Hongye Li, Zhonglai Qian, Xuzhu Gao and Mingming Liu

Front. Bioeng. Biotechnol., 2024, 11
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Comparative Study on the Microstructure and Biodegradation Behavior of Commercialized Pure Mg and Mg-1.0Ca-0.5Sr Alloy in 27 mM HCO3−-SBF: The Influence of the pH Regulation Treatments

Sabri Shafyra, Engku Mohammad Nazim, Nor Hasrul Akhmal Ngadiman and Izman Sudin

Metals, 2023, 13, 136
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From hard tissues to beyond: Progress and challenges of strontium-containing biomaterials in regenerative medicine applications

Liyun Wang, Shengjie Jiang, Jialiang Zhou, Mazaher Gholipourmalekabadi, Yuan Cao, Kaili Lin, Yu Zhuang and Changyong Yuan

Bioactive Materials, 2025, 49, 85
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Mechanistic insights and therapeutic applications of metal-based nanomaterials in oral infectious diseases: Current advances and future perspectives

Yijuan Wu, Jun Liao, Yicheng Pu, Lidong Gong, Xingyu Liu, Yuwei Wu, Qiang Zhang, Fen Gu, Yuanyuan Wang and Zhiqiang Lin

Biomaterials, 2026, 324, 123528
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Study on the Mechanism of Black Phosphorus Nanosheets Loading Sr2+ Used in Photothermal Antibacterial Treatment

Gaoqiang Ma, Binyang Li, Jiayong Diao, Yongzhi Zhang, Bing Zhang, Dongni Wu, Houda Gui, Junhao Zhong, Hongguang Zhu and Dongjiao Zhang

IJN, 2025, Volume 20, 1119
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Strontium-cerium surface functionalization of titanium scaffold: unlocking the potential of element incorporation for bone implant application

Ann Mary Mathew, Sreya P.V., Kalimuthu Vignesh, Chandran Manimegalai Swathi, Balamuthu Kadalmani and Deepak K. Pattanayak

Biomaterials Advances, 2026, 180, 214529
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Lithium‐Functionalized Sulfonated Polyetheretherketone with Dual Osteogenic‐Angiogenic Property: A One‐Step Bioactivation Strategy for Enhanced Implants Osseointegration

Linjun Yang, Zhuocheng Lyu, Xuhui Fan, Xu Zheng and You Wang

Adv Healthcare Materials, 2025, 14
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Materials‐Mediated In Situ Physical Cues for Bone Regeneration

Shuo Liu, Liguo Zhang, Zhao Li, Fei Gao, Qun Zhang, Alberto Bianco, Hong Liu, Shaohua Ge and Baojin Ma

Adv Funct Materials, 2024, 34
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Titanium implant can promote M2 polarization with macrophages activation which contribute to osteogenesis and angiogenesis via inactivates JAKS signaling pathway

Xiao Luo and Lin Xiao

BMC Immunol, 2025, 26
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Advanced applications of strontium-containing biomaterials in bone tissue engineering

Xiao Sheng, Chen Li, Zhonghan Wang, Yu Xu, Yang Sun, Weimin Zhang, He Liu and Jincheng Wang

Materials Today Bio, 2023, 20, 100636
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Enhancing the Osseointegration of Titanium Implants by Modulating M1/M2 Macrophage Polarization through PI3K-Akt Signal Pathway on a “Cortex-like” Microarc Oxidation Coating

Zijiao Zhang, Qijia Sui, Wenqi Fu, Xiaohua Dong, Xin Liu, Yuzhu He, Yaran Zang, Weiqiang Wang, Ni Kou and Huiying Liu

ACS Appl. Mater. Interfaces, 2025
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Comprehensive process optimization for rapidly vascularized osseointegration by dual ions effects

Wei Lu, Yangbo Xu, Hongke Luo, Hui Wang, Fengying Yin, Lingqing Dong and Fuming He

Chemical Engineering Journal, 2024, 497, 154520
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Enhanced functionalities of biomaterials through metal ion surface modification

Yujie Tao, Wayne Nishio Ayre, Liming Jiang, Siyu Chen, Yuqi Dong, Lin Wu, Yilai Jiao and Xiaohan Liu

Front. Bioeng. Biotechnol., 2025, 13
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Calcitonin gene-related peptide-modulated macrophage phenotypic alteration regulates angiogenesis in early bone healing

Qingci Kong, Siyong Gao, Pugeng Li, Hanyu Sun, Zhengchuan Zhang, Xiaolin Yu, Feilong Deng and Tianlu Wang

International Immunopharmacology, 2024, 130, 111766
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The application of nanomedicines in repairing damage in myocardial infarction

Saiqing Zheng, Dawei Chen, Ming Zhao and Haiyang Hu

Journal of Controlled Release, 2025, 388, 114388
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Enhancing Titanium-Osteointegration: Antimicrobial, anti-inflammatory and osteogenic properties of multifunctional coatings through Layer-by-Layer Self-Assembly

Danyang Xu, Xiaofeng Wang, Meiyu Li, Lei Xie, Kunjie Liu, Yihan Liu, Jinping Lan, Pengde Han, He Lin, Lili Song, Xuejiao Zhang and Yong Huang

Applied Surface Science, 2025, 686, 162149
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A new direction in periodontitis treatment: biomaterial-mediated macrophage immunotherapy

Shumin Peng, Haojie Fu, Rui Li, Hui Li, Shuyuan Wang, Bingyan Li and Jingjing Sun

J Nanobiotechnol, 2024, 22
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Combined intramyocardial injectable hydrogel and pericardial adhesive hydrogel patch therapy strategy to achieve gene/ion/gas delivery for improving cardiac function

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Nano Today, 2023, 50, 101861
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Cell-homing and immunomodulatory composite hydrogels for effective wound healing with neovascularization

Hayeon Byun, Yujin Han, Eunhyung Kim, Indong Jun, Jinkyu Lee, Hyewoo Jeong, Seung Jae Huh, Jinmyoung Joo, Su Ryon Shin and Heungsoo Shin

Bioactive Materials, 2024, 36, 185
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Crosstalk Between H-Type Vascular Endothelial Cells and Macrophages: A Potential Regulator of Bone Homeostasis

Jiaxuan Fan, Yaohui Xie, Desun Liu, Rui Cui, Wei Zhang, Mengying Shen and Linzhong Cao

JIR, 2025, Volume 18, 2743
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Oncostatin M regulates macrophages polarization in osseointegration via yes-associated protein

Ying Yuan, Qin Zhang, Bingfeng Wu, Tianyu Huang, Ping Gong and Lin Xiang

International Immunopharmacology, 2023, 120, 110348
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Inorganic ions for cartilage regeneration

Chaoqin Shu, Yongzheng Yu, Weitao Yang and Cuijun Deng

Coordination Chemistry Reviews, 2025, 543, 216942
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Emerging trends of injectable hydrogels for vital pulp therapy: A comprehensive review

Md Refat Readul Islam, Rafiqul Islam, Hidehiko Sano, Yu Toida, Shuhei Hoshika, Hany Mohamed Aly Ahmed and Atsushi Tomokiyo

Int Endodontic J, 2025, 58, 1490
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Regulated contribution of local and systemic immunity to new bone regeneration by modulating B/Sr concentration of bioactive borosilicate glass

Jingxin Ding, Jinhui Zhao, Lingtian Wang, Xiaochen Chen, Dajun Jiang, Muyan Qin, Ziyang Zhu, Deping Wang and Weitao Jia

Materials Today Bio, 2023, 19, 100585
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Strontium‐Doped Implant Osseointegration Under Dry Preservation Conditions: In Vitro and Rat Model‐Based In Vivo Studies

Jimin Jiang, Yingyu Zeng, Ibrahim El Khalil Bouhamed, Fangyuan Cai, Tianning Ye, Hui Wang, Sang Hyun Lee, Qianming Chen and Fuming He

Clin Implant Dent Rel Res, 2025, 27
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Advanced Bioresponsive Drug Delivery Systems for Promoting Diabetic Vascularized Bone Regeneration

Xiaojun Zhou, Shuo Chen, Andrij Pich and Chuanglong He

ACS Biomater. Sci. Eng., 2025, 11, 182
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NSUN2 methylates IRF4 to affect the capacity of macrophages attached to titanium implant on osteogenic differentiation of PDLSCs and angiogenesis of HUVECs in vitro

Li Xiao, Dongxue Wu, Tingting Zhang, Chang He, Xiaowei Guo and Hao Yang

BMC Oral Health, 2024, 24
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pH-Responsive silk protein/ZIF-8@bacitracin composite coating on strontium-doped nanorod surface for combating implant-associated infections

Zitong Tian, Jiaxin Guan, Hui Su, Lingdi Guan, Hao Yang, Chengcheng Xia, Pengde Han, He Lin, Xiaojun Zhang, Jinping Lan, Haixia Qiao, Yong Huang and Shengbo Sang

International Journal of Biological Macromolecules, 2025, 315, 144661
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A cytocompatible microporous Sr-doped titanium dioxide coating fabricated by plasma electrolytic oxidation

Hongming Zheng, Shuangjun He, Lijian Zhou, Jintao Yuan, Boyi Jiang, Xiaohui Ni, Kaihang Lu, Pengpeng Zhang and Quanming Zhao

Front. Mater., 2023, 10
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3D printed strontium-doped calcium phosphate ceramic scaffold enhances early angiogenesis and promotes bone repair through the regulation of macrophage polarization

Qiuju Miao, Xiaopeng Yang, Jingjing Diao, Huanwen Ding, Yan Wu, Xiangyang Ren, Jianbo Gao, Mengze Ma and Shenyu Yang

Materials Today Bio, 2023, 23, 100871
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Micro/nano-structured titanium surfaces promote endothelial responses and angiogenic activity under zoledronic acid exposure

Pugeng Li, Hanyu Sun, Xiaoyu Wang, Xuan Li, Qingci Kong, Feilong Deng, Yan Wang, Zhengchuan Zhang and Xiaolin Yu

BMC Oral Health, 2026
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SrCuSi4O10/GelMA Composite Hydrogel‐Mediated Vital Pulp Therapy: Integrating Antibacterial Property and Enhanced Pulp Regeneration Activity

Yu Qiu, Jun Tian, Siyi Kong, Yanping Feng, Yangyu Lu, Lefeng Su, Yanling Cai, Mengjie Li, Jiang Chang, Chen Yang and Xi Wei

Adv Healthcare Materials, 2023, 12
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Antibacterial bioadaptive scaffold promotes vascularized bone regeneration by synergistical action of intrinsic stimulation and immunomodulatory activity

Yuhan Qian, Chenglin Li, Qian Feng, Xiaojun Mao, Guang Yang, Shuo Chen, Tao Li, Xiaojun Zhou and Chuanglong He

Chemical Engineering Journal, 2024, 501, 157682
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Multifunctional Sr/Zn-doped TiO2 micro/nanoporous coating enhances osseointegration by modulating signaling crosstalk of bone-related cells

Tian-Xia Zheng, Nuo-Ya Yang, Jiu-Peng Deng, Wei Dong, Li-Fang Feng, Yuanyuan-Ding, Jin-Ping Yang, Xin-Jia Cai, Yan Liu and Meng-Chun Qi

Chemical Engineering Journal, 2025, 511, 161734
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A new paradigm in bone tissue biomaterials: Enhanced osteogenesis–angiogenic coupling by targeting H-type blood vessels

Qiheng Yang, Shibo Liu, Hanghang Liu, Yao Liu, Ze He, Zizhuo Zheng, Yanchi Chen and En Luo

Biomaterials, 2026, 324, 123423
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Effects of surface morphology and composition of titanium implants on osteogenesis and inflammatory responses: a review

Zhenbing Ji, Yi Wan, Hongwei Wang, Mingzhi Yu, Zihe Zhao, Teng Wang, Guoxuan Ma, Shiyuan Fan and Zhanqiang Liu

Biomed. Mater., 2023, 18, 042002
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A Comprehensive Review of the Contemporary Methods for Enhancing Osseointegration and the Antimicrobial Properties of Titanium Dental Implants

Fahad A Bakitian

Cureus, 2024
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An injectable phosphocreatine-grafted hydrogel incorporating hierarchically structured teriparatide/SrZnP-functionalized Zn–Cu particles for osteogenesis–angiogenesis coupling and osteoporotic bone regeneration

Haotian Qin, Zhiping Guan, Yuanhao Wang, Jin Zhao, Zhenhai Xie, Huaiyu Li, Chen Zhang, Weibei Sheng, Fei Yu, Jian Weng, Yingqi Chen, Deli Wang, Hui Zeng and Junyu Qian

Materials Today Bio, 2025, 35, 102272
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Osteogenic and antibacterial strontium-copper composite coating on SLA titanium surface

Zhen Lin, Jiali Liu, Yongting Mei, Xiaowei Cui, Yuchun Zou, Yanjing Ou, Li Li, Yuqing Zhang, Chengfei Zhang and Jiehua Su

Surfaces and Interfaces, 2026, 80, 108202
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Electrochemical Evaluation of Strontium-Doped Micro-Arc Oxidation Surfaces on Titanium

Alexandra C. Alves, Carolina Durães and Fatih Toptan

Metals, 2025, 15, 390
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Enhanced tissue infiltration and bone regeneration through spatiotemporal delivery of bioactive factors from polyelectrolytes modified biomimetic scaffold

Xiaojun Zhou, Zunjuan Wang, Tao Li, Zhonglong Liu, Xin Sun, Weizhong Wang, Liang Chen and Chuanglong He

Materials Today Bio, 2023, 20, 100681
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Advanced surface engineering of titanium materials for biomedical applications: From static modification to dynamic responsive regulation

Pinliang Jiang, Yanmei Zhang, Ren Hu, Bin Shi, Lihai Zhang, Qiaoling Huang, Yun Yang, Peifu Tang and Changjian Lin

Bioactive Materials, 2023, 27, 15
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A Multifunctional Metal–Phenolic Nanocoating on Bone Implants for Enhanced Osseointegration via Early Immunomodulation

Jin Liu, Yilin Shi, Yajun Zhao, Yue Liu, Xiaoru Yang, Kai Li, Weiwei Zhao, Jianmin Han, Jianhua Li and Shaohua Ge

Advanced Science, 2024, 11
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Phase-transformed lactoferrin/strontium-doped nanocoatings enhance antibacterial, anti-inflammatory and vascularised osteogenesis of titanium

Jiali Wang, Jiaxin Guan, Fengzhen Jia, Zitong Tian, Lili Song, Lei Xie, Pengde Han, He Lin, Haixia Qiao, Xuejiao Zhang and Yong Huang

International Journal of Biological Macromolecules, 2025, 287, 138608
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Three-Dimensional Semiconductor Network as Regulators of Energy Metabolism Drives Angiogenesis in Bone Regeneration

Youzhun Fan, Jiwei Sun, Wenjie Fan, Xianwei Zhong, Zhaoyi Yin, Bin Su, Jing Yao, Xinyu Hong, Jinxia Zhai, Zhengao Wang, Haoyan Chen, Fengyuan Guo, Xiufang Wen, Chengyun Ning, Lili Chen and Peng Yu

ACS Nano, 2024, 18, 32602
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Sr2+/Cu2+ Co-doped bone meal-recombinant collagen scaffold promotes bone regeneration through synergistic effects of immunomodulation, enhanced angiogenesis, and osteogenesis

Jiawei Huang, Wenyan Qiao, Jiaxin Yao, Wan Liu, Xiaoyan Zheng, Junfeng Hui, Xiufu Hua and Daidi Fan

Chemical Engineering Journal, 2025, 525, 170494
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Effects of the Dental Implant Surface Topography and Macrophage Polarisation on Osteogenesis and Angiogenesis

Bin Liu, Yanxiao Du, Mengya Wang, Zheng Zhang, Wenjie Yin, Yiming Hu and Feng Yang

International Dental Journal, 2026, 76, 109398
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Nanomaterials: Promising Tools for the Diagnosis and Treatment of Myocardial Infarction

Yanmin Ge, Lincong Wu, Shuyang Mei and Junduo Wu

IJN, 2025, Volume 20, 1747
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The Strontium Ion Reprograms Monocyte Subsets via TRPM2 Channel Regulation to Enhance Osseointegration

Congrui Zhao, Antian Xu, Jingyao Gong, Yangbo Xu, Ping Sun and Fuming He

Biomater Res, 2025, 29
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Investigating the early osteogenic potential of strontium doped titanium alloy surface

Ali Alenezi and Mohamed Ahmed Alkhodary

Journal of Applied Biomaterials & Functional Materials, 2025, 23
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