Issue 23, 2022

Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols

Abstract

We successfully constructed a new class of nanoflares based on ultra-thin silica-coated gold nanoparticles (Au@SiO2) with the covalent binding of nucleic acids, which demonstrated more resistance to biothiols than that exhibited in the traditional Au–S binding strategy, for imaging the target miRNA-21 with high fidelity in living cells.

Graphical abstract: Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols

Supplementary files

Article information

Article type
Communication
Submitted
31 अगस्त 2022
Accepted
06 नवम्बर 2022
First published
07 नवम्बर 2022

Analyst, 2022,147, 5269-5273

Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols

Y. Luo, Z. Wang, J. Li, W. Yi, K. Yang, C. Ou, L. Deng and D. He, Analyst, 2022, 147, 5269 DOI: 10.1039/D2AN01441F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements