Issue 42, 2021

Effect of structural features on the stability and bactericidal potential of two cadmium coordination polymers

Abstract

The emergence of new infectious diseases and their high mortality rate reveals the need for more attention to this area and the synthesis of new compounds. In this work, two mixed ligand cadmium(II) coordination polymers of [Cd(Phac)2(Dabco)(H2O)]n (1) and [Cd(Phac)(4,4′-Bpy)(OAc)]n (2) (Phac = phenylacetate, Dabco = 1,4-diazabicyclo[2.2.2]octane, 4,4′-Bpy = 4,4′-bipyridine, OAc = acetate) have been synthesized by the solvothermal, sonochemical and mechanochemical methods. Single-crystal X-ray diffraction analysis, Fourier-transform infrared (FT-IR) spectroscopy, X-ray powder diffraction (XRPD), field emission scanning electron microscopy (FE-SEM) and thermal techniques (TG-DTG) were used to study these compounds. In both compounds, phenylacetate is obtained by in situ decarboxylation of phenylmalonic acid. The stability and in vitro antibacterial activity of the compounds were investigated. Metal–ligand bond strength, pillar size, ligand shielding effect, and the nature of network expansion bonds were influential factors in the stability. More stability and the consequent higher lipophilicity of particles were associated with improved antibacterial activity for 1. Nano-grains in the bulk structure of compounds were also identified as a determining factor in antibacterial activity.

Graphical abstract: Effect of structural features on the stability and bactericidal potential of two cadmium coordination polymers

Supplementary files

Article information

Article type
Paper
Submitted
26 जुलाई 2021
Accepted
02 अक्तूबर 2021
First published
04 अक्तूबर 2021

CrystEngComm, 2021,23, 7450-7461

Effect of structural features on the stability and bactericidal potential of two cadmium coordination polymers

S. Soltani, K. Akhbari and J. White, CrystEngComm, 2021, 23, 7450 DOI: 10.1039/D1CE00979F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements