Issue 62, 2023

Ru(ii)/Ru(iv)-catalyzed C(sp2)–H allylation with alkene difunctionalization to access isochroman-1-imines

Abstract

Merging C(sp2)–H allylation and alkene difunctionalization events to access isochroman-1-imines, using N-aroyl aminoesters, MBH acetates, and NBS, under Ru(II)/Ru(IV) catalysis has been developed. Using 1H NMR, ESI-MS, HRMS, control reactions, deuterium labeling experiments, and DFT analysis, the allyl transfer (redox) process was proven to involve in C–H allylation rather than olefin insertion. Scale-up and synthetic transformations demonstrated the sustainability of this method.

Graphical abstract: Ru(ii)/Ru(iv)-catalyzed C(sp2)–H allylation with alkene difunctionalization to access isochroman-1-imines

Supplementary files

Article information

Article type
Communication
Submitted
31 मार्च 2023
Accepted
19 जून 2023
First published
19 जून 2023

Chem. Commun., 2023,59, 9497-9500

Ru(II)/Ru(IV)-catalyzed C(sp2)–H allylation with alkene difunctionalization to access isochroman-1-imines

A. Joshi, S. Moorthy, L. R. Chavada, S. K. Singh and A. K. Pandey, Chem. Commun., 2023, 59, 9497 DOI: 10.1039/D3CC01604H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements