Issue 18, 2019

A turn-on near-infrared fluorescent probe with rapid response and large Stokes shift for the selective and sensitive detection of zinc(ii) and its application in living cells

Abstract

Herein, a new near-infrared turn-on fluorescent probe, YPT, was designed and synthesized for the rapid detection of Zn2+, which exhibited low limit of detection for Zn2+ (12 nM) as well as a favorable large Stokes shift (λemλex = 168 nm). In addition, the probe showed rapid detection progress within 30 s, accompanied by a distinct change in fluorescence from colorless to bright red. Moreover, the sensing mechanism of YPT towards Zn2+ was supported by the Job's plot, HR-MS analysis, 1H NMR titration analysis and density functional theory (DFT) results. In addition, YPT was applied as a visible test strip for the detection of Zn2+. Finally, the NIR fluorescence imaging of Zn2+ was successfully performed in living cells using this probe. All the results indicate that this probe can be used to detect Zn2+ in both solution and living systems.

Graphical abstract: A turn-on near-infrared fluorescent probe with rapid response and large Stokes shift for the selective and sensitive detection of zinc(ii) and its application in living cells

Supplementary files

Article information

Article type
Paper
Submitted
22 फरवरी 2019
Accepted
02 अप्रैल 2019
First published
03 अप्रैल 2019

Anal. Methods, 2019,11, 2396-2403

A turn-on near-infrared fluorescent probe with rapid response and large Stokes shift for the selective and sensitive detection of zinc(II) and its application in living cells

W. Zhang, X. Jin, W. Chen, C. Jiang and H. Lu, Anal. Methods, 2019, 11, 2396 DOI: 10.1039/C9AY00380K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements