Issue 22, 2018

Mercaptopyrimidine-directed gold nanoclusters: a suitable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification

Abstract

Herein, we demonstrate a novel, facile, and suitable strategy for imaging GSH based on mercaptopyrimidine-directed gold nanoclusters (Au NCs). GSH can specifically induce the fluorescence enhancement of Au NCs by attacking the surface of the NCs to form dual ligand stabilized Au NCs at the millimolar level. Very importantly, the Au NCs can selectively image cancer cells.

Graphical abstract: Mercaptopyrimidine-directed gold nanoclusters: a suitable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification

Supplementary files

Article information

Article type
Communication
Submitted
23 मार्च 2018
Accepted
16 मई 2018
First published
16 मई 2018

J. Mater. Chem. B, 2018,6, 3650-3654

Mercaptopyrimidine-directed gold nanoclusters: a suitable fluorescent probe for intracellular glutathione imaging and selective cancer cell identification

Y. Zheng, W. Liu, Y. Chen, H. Jiang and X. Wang, J. Mater. Chem. B, 2018, 6, 3650 DOI: 10.1039/C8TB00791H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements