Issue 23, 2017

Advancements in infrared imaging platforms: complementary imaging systems and contrast agents

Abstract

Recent advancements in the infrared (IR) imaging system design as well as the co-development of compatible contrast agents have facilitated the potential application of fluorescence imaging systems for deep tissue diagnostics and real-time vasculature visualization for intraoperative surgical guidance. Compared to conventional imaging techniques that achieve superior tissue penetration depth through the use of high energy or ionizing radiation sources, complementary chemical compounds, also known as imaging probes or contrast agents, are required to enable enhancement of the imaging sensitivity required for improved image quality in the IR fluorescence imaging technique. Therefore, using a systems-level approach to plan research efforts where the requirements of the imaging setup are considered at the start of the contrast agent design to effectively improve detection sensitivity would reduce the technical entry barrier for the adoption of new technologies. In this paper, we highlight (1) the recent advancements and key operating differences in the reported IR imaging systems, and (2) the recent progress in creating biocompatible IR-emitting contrast agents as well as improving detection sensitivity using targeting agents. The ability to maximize the full benefits and performance of any IR imaging platform is highly reliant on the thorough understanding of the requirements of each imaging platform and the physical characteristics of the complementary contrast agents.

Graphical abstract: Advancements in infrared imaging platforms: complementary imaging systems and contrast agents

Article information

Article type
Highlight
Submitted
11 जनवरी 2017
Accepted
05 मई 2017
First published
05 मई 2017

J. Mater. Chem. B, 2017,5, 4266-4275

Advancements in infrared imaging platforms: complementary imaging systems and contrast agents

X. Zhao, S. He and M. C. Tan, J. Mater. Chem. B, 2017, 5, 4266 DOI: 10.1039/C7TB00123A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements