Issue 76, 2018

A halogen bond-donor amino acid for organocatalysis in water

Abstract

Herein we report a halogen bond-donor amino acid, 4-iodotetrafluorophenylalanine, which behaves as a catalyst for the aqueous synthesis of bis-(heterocyclic)methanes. We also provide experimental evidence that halogen bonding is a plausible explanation for the observed catalytic effect.

Graphical abstract: A halogen bond-donor amino acid for organocatalysis in water

Supplementary files

Article information

Article type
Communication
Submitted
24 जुलाई 2018
Accepted
30 अगस्त 2018
First published
30 अगस्त 2018

Chem. Commun., 2018,54, 10718-10721

A halogen bond-donor amino acid for organocatalysis in water

G. Bergamaschi, L. Lascialfari, A. Pizzi, M. I. Martinez Espinoza, N. Demitri, A. Milani, A. Gori and P. Metrangolo, Chem. Commun., 2018, 54, 10718 DOI: 10.1039/C8CC06010J

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