Themed collection Nanoscale Advances in Innovative Bioengineering
Application of nanomaterials in organoid culture and cryopreservation
Organoids are invaluable models for studying organ development, disease mechanism modelling, drug screening, and regenerative medicine.
Nanoscale Adv., 2025,7, 7483-7503
https://doi.org/10.1039/D5NA00534E
Enhanced Cytotoxic Activity of Moringa oleifera–Loaded Pharmacosomes against Neuroblastoma
Nanoscale Adv., 2026, Accepted Manuscript
https://doi.org/10.1039/D5NA00473J
Rosmarinic acid attenuates doxorubicin-induced cardiotoxicity: bio-nanocarrier system development and an in vitro study using H9c2 rat cardiomyocytes
Doxorubicin (DOX) is a potent chemotherapeutic agent widely used to treat various cancers, but its application is restricted by dose-limiting cardiotoxicity.
Nanoscale Adv., 2025,7, 7588-7597
https://doi.org/10.1039/D5NA00585J
Magnetoelectric/piezoelectric-based materials for coupled electrical and mechanical stimulation for bone repair: an in silico study
Bone repair is a complex process that requires the simultaneous presence of mechanical and electrical signals to replicate the physiological communication between acting forces, bone, and nerve cells.
Nanoscale Adv., 2025,7, 7768-7779
https://doi.org/10.1039/D5NA00520E
Exploring magnetoelectric nanoparticles for advanced nano-electroporation and drug delivery in interventional cardiology
Magnetoelectric nanoparticles can develop electric fields at their surface and in their surroundings, upon remote activation via a human-safe magnetic field. Such feature is explored to design innovative strategies for on-demand drug delivery.
Nanoscale Adv., 2025,7, 5978-5992
https://doi.org/10.1039/D5NA00438A
Bio-nanocoatings based on castor oil enhanced with nanomaterials as corrosion reducers in injection wells pipelines
Corrosion is a recurring problem in the oil and gas industries.
Nanoscale Adv., 2025,7, 5811-5827
https://doi.org/10.1039/D5NA00317B
Self-assembled Ac-FFA-NH2 based hydrogels with strong immunostimulating activity for vaccine delivery
The vaccine adjuvant-delivery system based on a biocompatible, self-assembling peptide hydrogel that enables sustained protein release and modulates the direction of the immune reaction to achieve a well-balanced immune response enhancement.
Nanoscale Adv., 2025,7, 4660-4672
https://doi.org/10.1039/D5NA00033E
RNA lipid nanoparticles stabilized during nebulization through excipient selection
High shear forces during nebulization can destabilize lipid nanoparticles with encapsulated RNA and lead to material loss. We demonstrated the impact of nebulization buffer composition on nanoparticle size, RNA encapsulation, and material recovery.
Nanoscale Adv., 2025,7, 4480-4489
https://doi.org/10.1039/D4NA01034E
Synthesis, characterization, and evaluation of low molecular weight poly(β-amino ester) nanocarriers for enhanced T cell transfection and gene delivery in cancer immunotherapy
Polymeric nanocarrier-mediated T cell transfection involves polymer synthesis, T cell isolation and activation, transfection with nanocarriers, and evaluation of uptake and gene delivery efficiency.
Nanoscale Adv., 2025,7, 3676-3691
https://doi.org/10.1039/D5NA00169B
About this collection
Guest edited by Su Zheng (The First Affiliated Hospital of University of Science and Technology of China, ORCID: 0000-0002-0719-9441), Le Zhicheng (National University of Singapore), and Gu Zhen (University of Science and Technology Beijing, ORCID: 0000-0001-8905-3018).
This collection includes work on:
- Nanoscale functional biomaterials including the development and application of bioelectronic materials, responsive materials, smart materials, programmable materials, biocompatibility and biodegradability, immunomodulatory materials, integration with micro and nanotechnology, and personalized smart materials.
- Frontiers of nanobioprinting techniques include high-resolution bioprinting, multi-material printing, dynamic bioprinting, cell microenvironment optimization, tissue engineering scaffolds, functional organ and tissue models, high-throughput bioprinting, personalized medicine, novel bioinks, and clinical translation.
- Other cutting nanobiotechnology research of innovative bioengineering include gene editing technologies, synthetic biology, biomanufacturing, tissue engineering and regenerative medicine, bioinformatics and systems biology, immunoengineering, microfluidics and organs-on-chips, biomaterials, biosensors, neuroengineering, bio-robotics, environmental bioengineering, nanobiotechnology, single-cell technologies, and interdisciplinary collaboration.