Anthony R. Carroll, Brent R. Copp, Rohan A. Davis, Robert A. Keyzers and Michèle R. Prinsep

Nat. Prod. Rep., 2023, 40, 275
DOI: 10.1039/D2NP00083K

Volatile organic compounds (VOCs) in terrestrial extreme environments: implications for life detection beyond Earth

Claire A. Batty, Victoria K. Pearson, Karen Olsson-Francis and Geraint Morgan

Nat. Prod. Rep., 2025, 42, 93
DOI: 10.1039/D4NP00037D

Unlocking marine treasures: isolation and mining strategies of natural products from sponge-associated bacteria

Jeong-A. Kim, Si-sun Choi, Jae Kyu Lim and Eung-Soo Kim

Nat. Prod. Rep., 2025, 42, 1195
DOI: 10.1039/D5NP00013K

Building a highly efficient Streptomyces super-chassis for secondary metabolite production by reprogramming naturally-evolved multifaceted shifts

Shiwen Qiu, Bowen Yang, Zilong Li, Shanshan Li, Hao Yan, Zhenguo Xin, Jingfang Liu, Xuejin Zhao, Lixin Zhang, Wensheng Xiang and Weishan Wang

Metabolic Engineering, 2024, 81, 210
DOI: 10.1016/j.ymben.2023.12.007

Promoting Butenyl-spinosyn Production Based on Omics Research and Metabolic Network Construction in Saccharopolyspora pogona

Jie Rang, Li Cao, Ling Shuai, Yang Liu, Zirong Zhu, Ziyuan Xia, Duo Jin, Yunjun Sun, Ziquan Yu, Shengbiao Hu, Qingji Xie and Liqiu Xia

J. Agric. Food Chem., 2022, 70, 3557
DOI: 10.1021/acs.jafc.2c00285

Argenteolides A and B, Glycosylated Polyketide–Peptide Hybrid Macrolides from an Actinomycete Streptomyces argenteolus

Zhiguo Liu, Yoko Yashiroda, Peng Sun, Hai Ma, Yanan Wang, Li Li, Fu Yan and Yi Sun

Org. Lett., 2023, 25, 571
DOI: 10.1021/acs.orglett.2c03290

3-Amino-4-hydroxybenzoic acid production from glucose and/or xylose via recombinant Streptomyces lividans

Satoko Niimi-Nakamura, Hideo Kawaguchi, Kouji Uematsu, Hiroshi Teramura, Sachiko Nakamura-Tsuruta, Norimasa Kashiwagi, Yoshinori Sugai, Yohei Katsuyama, Yasuo Ohnishi, Chiaki Ogino and Akihiko Kondo

J. Gen. Appl. Microbiol., 2022, 68, 109
DOI: 10.2323/jgam.2022.06.001

Marine drugs: Biology, pipelines, current and future prospects for production

Nicolas Papon, Brent R. Copp and Vincent Courdavault

Biotechnology Advances, 2022, 54, 107871
DOI: 10.1016/j.biotechadv.2021.107871

The Transcriptional Regulator DhyR Positively Modulates Daptomycin Biosynthesis in Streptomyces roseosporus

Fuqiang He, Xinpeng Liu, Haiyi Wang, Xu Li, Yun Wu, Dan Zhang and Shufang Liang

Microbial Biotechnology, 2025, 18
DOI: 10.1111/1751-7915.70110

Cytotoxic metabolites from the marine-associated Streptomyces sp. ZZ1944

Wenwen Yi, Xiao-Yuan Lian and Zhizhen Zhang

Phytochemistry, 2022, 201, 113292
DOI: 10.1016/j.phytochem.2022.113292

Combining culture optimization and synthetic biology to improve production and detection of secondary metabolites in Myxococcus xanthus : application to myxoprincomide

Mathieu Sourice, Charlotte Simmler, Marc Maresca, Béatrice Py, Corinne Aubert and Neha Garg

Microbiol Spectr, 2024, 12
DOI: 10.1128/spectrum.01740-24

Whole genome analysis of Streptomyces sp. RerS4, a Rehmannia glutinosa rhizosphere microbe producing a new lipopeptide

Hairong He, Jiarui Huang, Zhenzhu Zhao, Pengqiang Du, Jiansong Li, Jile Xin, Huifang Xu, Weisheng Feng and Xiaoke Zheng

Heliyon, 2023, 9, e19543
DOI: 10.1016/j.heliyon.2023.e19543

A guide to genome mining and genetic manipulation of biosynthetic gene clusters in Streptomyces

Heonjun Jeong, YeonU Choe, Jiyoon Nam and Yeon Hee Ban

Journal of Microbiology, 2025, 63, e2409026
DOI: 10.71150/jm.2409026

Separation and identification of nematicidal active compounds in culture filtrate of Streptomyces aquilus JXGZ01 based on metabolomic analysis

Xueliang Xu, Caiyun Wu, Linjuan Fan, Fan Zhang, Jian Yao, Zirong Liu and Yingjuan Yao

Pest Management Science, 2025, 81, 4590
DOI: 10.1002/ps.8816

Genome-guided approaches and evaluation of the strategies to influence bioprocessing assisted morphological engineering of Streptomyces cell factories

Khushboo, Mony Thakur, Punit Kumar, Deepanshi Rajput, Vinod Yadav, Namrata Dhaka, Rishikesh Shukla and Kashyap Kumar Dubey

Bioresource Technology, 2023, 376, 128836
DOI: 10.1016/j.biortech.2023.128836

Molecular mechanism of GylR-mediated regulation of glycerol metabolism in Streptomyces clavuligerus NRRL 3585

Chaobo Zhang, Youbao Zhao, Zilong Li, Weishan Wang, Ying Huang, Guohui Pan and Keqiang Fan

Front. Microbiol., 2022, 13
DOI: 10.3389/fmicb.2022.1078293

Agarose Degrading Potential and Whole Genome Sequence Analysis of Marine Bacterium Aliagarivorans sp. Strain DM1 Isolated from the Arabian Sea

Madhav Kumar, Meenakshi and Doongar R. Chaudhary

Curr Microbiol, 2024, 81
DOI: 10.1007/s00284-024-03949-6

Development of a salt-enhanced promoter strategy for activating silent biosynthetic gene clusters from streptomycetes

Lijuan Wang, Mengyi Zhu, Chunfang Yang, Siqi Zhu, Bin Tan, Shu-Hua Qi, Yiguang Zhu and Changsheng Zhang

Metabolic Engineering, 2025, 92, 51
DOI: 10.1016/j.ymben.2025.07.007

Deciphering mechanisms of production of natural compounds using inducer-producer microbial consortia

Miroslav Gasparek, Harrison Steel and Antonis Papachristodoulou

Biotechnology Advances, 2023, 64, 108117
DOI: 10.1016/j.biotechadv.2023.108117

Synthetic biology approaches to actinomycete strain improvement

Rainer Breitling, Martina Avbelj, Oksana Bilyk, Francesco Del Carratore, Alessandro Filisetti, Erik K R Hanko, Marianna Iorio, Rosario Pérez Redondo, Fernando Reyes, Michelle Rudden, Emmanuele Severi, Lucija Slemc, Kamila Schmidt, Dominic R Whittall, Stefano Donadio, Antonio Rodríguez García, Olga Genilloud, Gregor Kosec, Davide De Lucrezia, Hrvoje Petković, Gavin Thomas and Eriko Takano

FEMS Microbiology Letters, 2021, 368
DOI: 10.1093/femsle/fnab060

A bioprocess perspective on the production of secondary metabolites by Streptomyces in submerged co-cultures

Tomasz Boruta

World J Microbiol Biotechnol, 2021, 37
DOI: 10.1007/s11274-021-03141-z

Streptomyces as Microbial Chassis for Heterologous Protein Expression

Soonkyu Hwang, Yongjae Lee, Ji Hun Kim, Gahyeon Kim, Hyeseong Kim, Woori Kim, Suhyung Cho, Bernhard O. Palsson and Byung-Kwan Cho

Front. Bioeng. Biotechnol., 2021, 9
DOI: 10.3389/fbioe.2021.804295

Streptomyces: Still the Biggest Producer of New Natural Secondary Metabolites, a Current Perspective

Lavinia Donald, Atanas Pipite, Ramesh Subramani, Jeremy Owen, Robert A. Keyzers and Taitusi Taufa

Microbiology Research, 2022, 13, 418
DOI: 10.3390/microbiolres13030031

Context matters: assessing the impacts of genomic background and ecology on microbial biosynthetic gene cluster evolution

Rauf Salamzade, Lindsay R. Kalan and Jonathan L. Klassen

mSystems, 2025, 10
DOI: 10.1128/msystems.01538-24

Double‐reporter‐guided targeted activation of the oxytetracycline silent gene cluster in Streptomyces rimosus M527

Yue Shi, Jinyao Zhang, Zheng Ma, Yongyong Zhang, Andreas Bechthold and Xiaoping Yu

Biotech & Bioengineering, 2023, 120, 1411
DOI: 10.1002/bit.28347

Fermentation optimization and metabolomic analysis of ε-polylysine production in Streptomyces albulus

Yuanyuan Yu, Li Xia and Jianping Wen

Biochemical Engineering Journal, 2025, 220, 109758
DOI: 10.1016/j.bej.2025.109758

RETRACTED: Jejupeptins A and B: Polyketide–Cyclic Peptide Hybrids with Anti-Corticosterone Activity from Streptomyces sp. KCB15JA151

Jun-Pil Jang, Jongtae Roh, Gil Soo Kim, Jihun Park, Gwi Ja Hwang, Beomcheol Park, Hyeok-Won Lee, Shunji Takahashi, Young-Soo Hong, Sung-Kyun Ko and Jae-Hyuk Jang

J. Nat. Prod., 2025, 88, 433
DOI: 10.1021/acs.jnatprod.4c01201

Plant Pyranocoumarins: Description, Biosynthesis, Application

Maria T. Khandy, Anastasia K. Sofronova, Tatiana Y. Gorpenchenko and Nadezhda K. Chirikova

Plants, 2022, 11, 3135
DOI: 10.3390/plants11223135

Natural product discovery in soil actinomycetes: unlocking their potential within an ecological context

Jana K Schniete and Lorena T Fernández-Martínez

Current Opinion in Microbiology, 2024, 79, 102487
DOI: 10.1016/j.mib.2024.102487

Critical Secondary Metabolites Confer the Broad-Spectrum Pathogenic Fungi Resistance Property of a Marine-Originating Streptomyces sp. HNBCa1

Zijun Xiong, Tengfei Xia, Weicheng Wu, Rong Wang, Min Qi, Shiqing Zhang, Jitao Li, Yang Yang, Daojun Zheng, Shuangjun Lin and Zhikai Guo

J. Agric. Food Chem., 2024, 72, 13164
DOI: 10.1021/acs.jafc.4c02805

Characterization of Bioactivities and Biosynthesis of Angucycline/Angucyclinone Derivatives Derived from Gephyromycinifex aptenodytis gen. nov., sp. nov.

Wen-Zhuo Zhu, Shu-Heng Wang, Hui-Min Gao, Ya-Ming Ge, Jun Dai, Xiao-Ling Zhang and Qiao Yang

Marine Drugs, 2021, 20, 34
DOI: 10.3390/md20010034

Exploring bioactive compound origins: Profiling gene cluster signatures related to biosynthesis in microbiomes of Sof Umer Cave, Ethiopia

Abu Feyisa Meka, Gessesse Kebede Bekele, Musin Kelel Abas, Mesfin Tafesse Gemeda and Richa Salwan

PLoS ONE, 2025, 20, e0315536
DOI: 10.1371/journal.pone.0315536

Recent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological applications

Nitesh Kumar Mund and Eva Čellárová

Biotechnology Advances, 2023, 63, 108104
DOI: 10.1016/j.biotechadv.2023.108104

Decoding genomic potential of Streptomyces spp. for sustainable environment and industries

Bhawana Jangra, Vagish Dwibedi, Gursharan Kaur and Pooja Bhadrecha

South African Journal of Botany, 2025, 184, 480
DOI: 10.1016/j.sajb.2025.06.022

Enhancing surfactin production in Bacillus subtilis: Insights from proteomic analysis of nitrate-induced overproduction and strategies for combinatorial metabolic engineering

Li Xia, Zhengjie Hou, Fuzhou Zhu and Jianping Wen

Bioresource Technology, 2024, 397, 130499
DOI: 10.1016/j.biortech.2024.130499

Phenotypic heterogeneity in Streptomyces colonies

Paul A Hoskisson, Francisco Barona-Gómez and Daniel E Rozen

Current Opinion in Microbiology, 2024, 78, 102448
DOI: 10.1016/j.mib.2024.102448

Comparative and pangenomic analysis of the genus Streptomyces

Hiroshi Otani, Daniel W. Udwary and Nigel J. Mouncey

Sci Rep, 2022, 12
DOI: 10.1038/s41598-022-21731-1

Heterologous overproduction of oviedomycin by refactoring biosynthetic gene cluster and metabolic engineering of host strain Streptomyces coelicolor

Boncheol Gu, Duck Gyun Kim, Do-Kyung Kim, Minji Kim, Hyun Uk Kim and Min-Kyu Oh

Microb Cell Fact, 2023, 22
DOI: 10.1186/s12934-023-02218-8

The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes

Diethard Mattanovich, Pablo Ivan Nikel, Christopher M. Whitford, Pablo Cruz-Morales, Jay D. Keasling and Tilmann Weber

Essays in Biochemistry, 2021, 65, 261
DOI: 10.1042/EBC20200132

Inhibition of heterotrophic bacterial biofilm in the soil ferrosphere by Streptomyces spp. and Bacillus velezensis

Nataliia Tkachuk and Liubov Zelena

Biofouling, 2022, 38, 916
DOI: 10.1080/08927014.2022.2151362

Improving the Yield of Xenocoumacin 1 by PBAD Promoter Replacement in Xenorhabdus nematophila CB6

Youcai Qin, Fenglian Jia, Xiaohui Li, Beibei Li, Jie Ren, Xiufen Yang and Guangyue Li

Agriculture, 2021, 11, 1251
DOI: 10.3390/agriculture11121251

Expanding the Chemical Diversity of Fasamycin Via Genome Mining and Biocatalysis

Kai Jiang, Xiaoli Yan, Zixin Deng, Chun Lei and Xudong Qu

J. Nat. Prod., 2022, 85, 943
DOI: 10.1021/acs.jnatprod.1c01089

Metabolic engineering of Micromonospora for exploring useful natural products and phytobiotic interaction

Boncheol Gu, Jimin Lee, Duck Gyun Kim, Yu-jin Cha and Min-Kyu Oh

Metabolic Engineering, 2025, 92, 39
DOI: 10.1016/j.ymben.2025.07.005

Metabolomics- and systems-biology-guided discovery of metabolite lead compounds and druggable targets

Amelia Palermo

Drug Discovery Today, 2023, 28, 103460
DOI: 10.1016/j.drudis.2022.103460

Combinatorial strain improvement and bioprocess development for efficient production of ε-poly-L-lysine in Streptomyces albulus

Daojun Zhu, Yuxiang Liu, Hao Yang, Jiawei Zhang, Gencheng Zheng, Hongjian Zhang, Liang Wang, Jianhua Zhang and Xusheng Chen

Bioresource Technology, 2024, 407, 131123
DOI: 10.1016/j.biortech.2024.131123

Sulfane Sulfur Posttranslationally Modifies the Global Regulator AdpA to Influence Actinorhodin Production and Morphological Differentiation of Streptomyces coelicolor

Ting Lu, Xiaohua Wu, Qun Cao, Yongzhen Xia, Luying Xun, Huaiwei Liu, Christiane Dahl and Caroline S. Harwood

mBio, 2022, 13
DOI: 10.1128/mbio.03862-21

Transcriptionally induced nucleoid-associated protein-like ccr1 in combined-culture serves as a global effector of Streptomyces secondary metabolism

Yukun Lei, Hiroyasu Onaka and Shumpei Asamizu

Front. Microbiol., 2024, 15
DOI: 10.3389/fmicb.2024.1422977

Mycelial differentiation linked avermectin production in Streptomyces avermitilis studied with Raman imaging

Shumpei Horii, Ashok Zachariah Samuel, Takuji Nakashima, Akira Take, Atsuko Matsumoto, Yoko Takahashi, Masahiro Ando and Haruko Takeyama

Appl Microbiol Biotechnol, 2023, 107, 369
DOI: 10.1007/s00253-022-12314-1

Actinomycetes are a natural resource for sustainable pest control and safeguarding agriculture

Mohamed Khaled Diab, Hala Mohamed Mead, Mohamad M. Ahmad Khedr, Abdelghafar Mohamed Abu-Elsaoud and Sahar Ahmed El-Shatoury

Arch Microbiol, 2024, 206
DOI: 10.1007/s00203-024-03975-9