Mannich-type allylic C–H functionalization of enol silyl ethers under photoredox–thiol hybrid catalysis†
Kohsuke
Ohmatsu 
a
and
Takashi
Ooi
*a
a
and
Takashi
Ooi
*a
Abstract
The synergy of an Ir-based photosensitizer with mild oxidizing ability and a thiol catalyst enables efficient allylic C–H functionalization of enol silyl ethers with imines under visible light irradiation. Subsequent transformations of the aminoalkylated enol silyl ethers allow for the facile construction of unique molecular frameworks such as functionalized octahydroisoindol-4-one.
- This article is part of the themed collections: Editor’s Collection, Hybrid Catalysis and Synthetic methodology in OBC
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