Issue 25, 2023
From the journal:

Nanoscale

Histidine–DNA nanoarchitecture as laccase mimetic DNAzymes†

Ji Hye Yum,a   Tomotaka Kumagai,a   Daisuke Hori,a   Hiroshi Sugiyama ORCID logo *ab  and  Soyoung Park ORCID logo *c  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan

b Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Yoshida-ushinomiyacho, Sakyo-ku, Kyoto 606-8501, Japan

c Immunology Frontier Research Center, Osaka University, Yamadaoka, Suita, Osaka, Japan
E-mail: spark@ifrec.osaka-u.ac.jp

Abstract

Herein, we report on the construction of Cu–histidine (His)–DNA hybrids as laccase-mimetic DNAzymes. Cu–His–DNAzymes showed remarkable activity in a colorimetric oxidation reaction between 2,4-dichlorophenol and 4-aminoantipyrine. Our results provide new insights for the systematic construction of tailor-made active sites for biomimetics.

Graphical abstract: Histidine–DNA nanoarchitecture as laccase mimetic DNAzymes

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Article information

DOI
https://doi.org/10.1039/D3NR01625K
Article type
Paper
Submitted
08 אפר 2023
Accepted
10 יונ 2023
First published
16 יונ 2023
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2023,15, 10749-10754

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Histidine–DNA nanoarchitecture as laccase mimetic DNAzymes

J. H. Yum, T. Kumagai, D. Hori, H. Sugiyama and S. Park, Nanoscale, 2023, 15, 10749 DOI: 10.1039/D3NR01625K

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