Issue 43, 2021

Molecular platforms based on biocompatible photoreactions for photomodulation of biological targets

Abstract

Photoirradiation provides a convenient and biocompatible approach for spatiotemporal modulation of biological systems with photoresponsive components. The construction of molecular platforms with a photoresponse to be integrated into biomolecules for photomodulation has been of great research interest in optochemical biology. In this review, we summarize typical molecular platforms that are integratable with biomolecules for photomodulation purposes. We categorize these molecular platforms according to their excitation light source, namely ultraviolet (UV), visible (Vis) or near-infrared (NIR) light. The protype chemistry of these molecular platforms is introduced along with an overview of their most recent applications for spatiotemporal regulation of biomolecular function in living cells or mice models. Challenges and the outlook are also presented. We hope this review paper will contribute to further progress in the development of molecular platforms and their biomedical use.

Graphical abstract: Molecular platforms based on biocompatible photoreactions for photomodulation of biological targets

Article information

Article type
Review Article
Submitted
17 אוג 2021
Accepted
16 ספט 2021
First published
17 ספט 2021

Org. Biomol. Chem., 2021,19, 9358-9368

Molecular platforms based on biocompatible photoreactions for photomodulation of biological targets

C. Zhu, T. Kou, A. A. Kadi, J. Li and Y. Zhang, Org. Biomol. Chem., 2021, 19, 9358 DOI: 10.1039/D1OB01613J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements