Issue 95, 2021

Multichannel dual protein sensing using amphiphilic supramolecular assemblies

Abstract

Protein sensing strategies have implications in detection of many human pathologies. Here, a supramolecular strategy for sensing two different proteins using a multichannel readout approach is outlined. Protein–ligand binding or enzymatic cleavage can both be programmed to induce supramolecular disassembly, which leads to fluorescence enhancement via aggregation-induced emission (AIE), protein-induced fluorescence enhancement (PIFE), or disassembly-induced fluorescence enhancement (DIFE). The accompanying signal change from two different fluorophores and their patterns are then used for specific protein sensing.

Graphical abstract: Multichannel dual protein sensing using amphiphilic supramolecular assemblies

Supplementary files

Article information

Article type
Communication
Submitted
24 ספט 2021
Accepted
06 נוב 2021
First published
08 נוב 2021

Chem. Commun., 2021,57, 12828-12831

Multichannel dual protein sensing using amphiphilic supramolecular assemblies

J. Gao, T. Prachyathipsakul and S. Thayumanavan, Chem. Commun., 2021, 57, 12828 DOI: 10.1039/D1CC05407D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements