Issue 24, 2015

A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(iii) pools in C. elegans

Abstract

The discovery of an iron(III)-selective ratiometric fluorescent probe to detect and visualize endogenous labile iron pools in living organisms at the molecular level has been long awaited. Herein we report the first dual colorimetric and ratiometric fluorescent probe naphtho[2,1-b][1,10]phenanthroline NAP-3 for selective and ‘direct’ visualization of labile iron(III) pools in a multicellular organism, Caenorhabditis elegans.

Graphical abstract: A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(iii) pools in C. elegans

Supplementary files

Article information

Article type
Communication
Submitted
08 דצמ 2014
Accepted
19 ינו 2015
First published
21 ינו 2015

Chem. Commun., 2015,51, 5001-5004

A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(III) pools in C. elegans

A. Goel, S. Umar, P. Nag, A. Sharma, L. Kumar, Shamsuzzama, Z. Hossain, J. R. Gayen and A. Nazir, Chem. Commun., 2015, 51, 5001 DOI: 10.1039/C4CC09798J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements