Issue 10, 2011

Perspectives in imaging using mass spectrometry

Abstract

Imaging mass spectrometry (MS) allows a remarkable range of measurements including diagnosis of disease state of tissue based on detailed information on its chemical constituents, especially lipids and proteins. The recent emergence of ambient ionization allows imaging in the open environment without sample preparation. In this review, we briefly describe the history of imaging MS highlighting its main techniques and applications. We also demonstrate how the detailed molecular information obtained by imaging MS makes this technique suitable for a range of forensic and clinical applications with the potential to be successfully developed all the way to intra-surgical practice.

Graphical abstract: Perspectives in imaging using mass spectrometry

Article information

Article type
Highlight
Submitted
27 אוג 2010
Accepted
15 נוב 2010
First published
16 דצמ 2010

Chem. Commun., 2011,47, 2741-2746

Perspectives in imaging using mass spectrometry

A. L. Dill, L. S. Eberlin, D. R. Ifa and R. G. Cooks, Chem. Commun., 2011, 47, 2741 DOI: 10.1039/C0CC03518A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements