Emily A. Hoff, Brooks A. Abel, Chase A. Tretbar, Charles L. McCormick and Derek L. Patton
Polym. Chem., 2017,8, 4978-4982
DOI:
10.1039/C6PY01563H,
Communication
We report aqueous RAFT polymerization at pH = 0 mediated by a novel imidazolium-containing chain transfer agent. In 1 M HCl, unprecedented controlled polymerization and chain-extension of unprotected acyl hydrazide methacrylamides is achieved enabling the synthesis of well-defined acyl hydrazide functionalized polymer scaffolds of interest for dynamic covalent and bioconjugation strategies.