N-Benzylation of isotoic anhydride in the presence of sodium hydride base is a very common reaction. However, it produces various byproducts. Here, we will identify a major byproduct and its activities.
Electrophilic water-soluble compounds have proven versatile in reacting selectively with 2′-OH groups in RNA, enabling structure mapping, probing, caging, labeling, crosslinking, and conjugation of RNAs in vitro and in living cells.
DFT calculations uncovered that the isatoic anhydride is a masked directing group and internal oxidant for Rh(III)-catalyzed decarbonylative annulation through C–H activation.
This review presents all the recent reports on electro- and photochemical reactions of isatins over the last decade.
In this study, CS-[BiC-PiC]-NiCl4 was designed, synthesized, and fully characterized by using various techniques. In continue this reagent was used for the promotion of the synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives.