Aloe vera polysaccharides mitigate high-fat high-cholesterol diet-induced atherosclerosis in ApoE−/− mice via regulation of lipid metabolism and gut microbiota

Shenji Yang, Xiaojun Huang, Xiajialong Li, Jing Feng, Peng Chen, Zhikang Cao, Luyao He, Chaojun Li, Zhipeng Li and Mingyong Xie

Food Funct., 2025, 16, 6671
DOI: 10.1039/D5FO01995H

Regulating Effects of Three Polysaccharides on Gut Microbiota in Felines and Canines: Insights from In Vitro Digestion, Fecal Fermentation, and Lactic Acid Bacterial Fermentation

Huasong Bai, Tong Liu, Hengyan Wang, Yunliang Li and Zhanzhong Wang

J. Agric. Food Chem., 2025, 73, 9618
DOI: 10.1021/acs.jafc.4c12847

Mucoadhesive β-glucan–bilirubin self-assembling oral nanomedicine alleviates colitis via reactive oxygen species scavenging and gut microbiota modulation

Junlong Chen, Pei Xie, Yiqing Long, Yaxue Liu, Xiaozeliang Zhou, Yu Li and Zongning Yin

Chemical Engineering Journal, 2025, 523, 168540
DOI: 10.1016/j.cej.2025.168540

Proanthocyanidins Inhibit Neuroinflammation in High-Fat-Induced Obese Mice by Modulating Intestinal Flora and Their Metabolites

Min Yao, Xiaotong Pang, Hailiang Wang, Cunxi Nie, Ruolin Huang, Fang Wang, Heng Zhao, Wenna Tang, Yueran Hao and Yixin Ren

Nutrients, 2026, 18, 431
DOI: 10.3390/nu18030431

Potential Application of Natural Products in Weight Management and Obesity: Focusing on the Gut Microbiota

Shiqiong Huang, Zheng Zhou and Gefei He

Phytotherapy Research, 2026
DOI: 10.1002/ptr.70267

Atraric Acid Ameliorates Neurological Dysfunction in High-Fat Diet-Fed Mice by Activating Autophagy to Alleviate Brain Oxidative Stress and Neuroinflammation

Yixuan Wang, Xiaoli Xie, Baihao Zhang, Shan Gao, Yannan Xiang, Yong Sun and Xinying Guan

Mol Neurobiol, 2026, 63
DOI: 10.1007/s12035-025-05525-w

Akkermansia muciniphila- derived extracellular vesicles alleviate colitis-related cognitive impairment via tryptophan metabolic reprogramming of the gut‒brain axis

Xinyang Chen, Qiqiong Li, Wanyu Zhang, Yushan Xu, Xinke Nie, Xindong Wang, Chunhua Chen, Junhua Xie and Shaoping Nie

Gut Microbes, 2026, 18
DOI: 10.1080/19490976.2025.2611546

Lidocaine intervention attenuated postoperative delirium by reshaping intestinal flora and modulating microglia M2 type polarization and blood-brain barrier

Fanghua Xie, Qiang Du, Qingfu Wang, Wenying Lu, Shaobo Song and Jing Yu

Biochemical and Biophysical Research Communications, 2025, 778, 152301
DOI: 10.1016/j.bbrc.2025.152301

Extraction and purification, structural characteristics, biological activities, applications, and quality control of Aloe vera polysaccharides: A review

Duo Li, Hong-wei Wang, An-dong Dong, Qiao Zhang, Changli Wang, Jing Wang, Jing Sun and Chongbo Zhao

International Journal of Biological Macromolecules, 2025, 329, 147927
DOI: 10.1016/j.ijbiomac.2025.147927

Multi-omics reveals that 4′-O-β-D-glucosyl-5-O-methylvisamminol ameliorates acute liver injury by modulating the miR-30e-3p/Tfrc axis and a multi-dimensional network of ferroptosis, inflammation, metabolism, and gut microbiota

Tingwen Zhang, Ruihong Zou, Zheng Chen, Yawei Li, Xin Sun and Xialin Sun

Phytomedicine, 2026, 154, 158022
DOI: 10.1016/j.phymed.2026.158022

The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation

Jialin Wu, Guosen Ou, Shiqi Wang, Yaokang Chen, Lu Xu, Li Deng, Huachong Xu and Xiaoyin Chen

EPMA Journal, 2024, 15, 587
DOI: 10.1007/s13167-024-00379-z

Supplementation of glucomannans ameliorate high-fat diet–induced cognitive impairment via a gut microbiota–metabolite–glutamatergic synapse axis

Zhikang Cao, Huiying Liu, Peng Chen, Shenji Yang, Xiajialong Li, Zhixin Chen, Jing Feng, Liyue Chen, Jiaqiang Lin, Zixuan Fu, Qixing Nie and Zhipeng Li

International Journal of Biological Macromolecules, 2026, 357, 151705
DOI: 10.1016/j.ijbiomac.2026.151705

The role of gut microbiota in disease management: Ayurvedic perspectives on metabolic diseases and health

Bhawana Jangra, Shreyanshi Kulshreshtha, Alok Goyal and Sanjay M. Jachak

Phytomedicine Plus, 2025, 5, 100731
DOI: 10.1016/j.phyplu.2025.100731

Correlation between depressive-like behavior and gut microbiota in mice with hypothyroidism

Han-Jie Guo, Xiao-Qing Ma, Yan-Ting Li, Zhao-Han Zhou, Wei Tao, Yu-Hao Jiang, Xiao-Long Li and Xi-Liang Zhang

World J Psychiatry, 2025, 15
DOI: 10.5498/wjp.v15.i7.104921

Multimodal Interventions Targeting Gut Microbiota and Microbial Metabolites in Cognitive Impairment

Paulina Horwat, Agnieszka Mariowska, Anita Szymanska, Marta Dzieciatkowska and Weronika Pierudzka

Cureus, 2025
DOI: 10.7759/cureus.85688

Coix Seed Extract Attenuates Glycolipid Metabolism Disorder in Hyperlipidemia Mice Through PPAR Signaling Pathway Based on Metabolomics and Network Pharmacology

Min Wang, Tianming Yang, Yongjing Xiang, Junxiao Pang, Yao Wang and Dali Sun

Foods, 2025, 14, 770
DOI: 10.3390/foods14050770