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Green Chem., 2025, 27, 3693
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Yarrowia lipolytica: A promising microbial platform for sustainable squalene production

Hany Elsharawy and Moath Refat

Biocatalysis and Agricultural Biotechnology, 2024, 57, 103130
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Reconstitution and optimization of complex plant natural product biosynthetic pathways in microbial expression systems

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Enhancing Precursor Supply and Engineering Efflux Systems to Improve Abscisic Acid Production and Secretion in Yarrowia lipolytica

Mei-Li Sun, Yun Xu, Lu Lin, Jian Gao, Rodrigo Ledesma-Amaro, Kaifeng Wang and Xiao-Jun Ji

J. Agric. Food Chem., 2025, 73, 6050
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Emerging trends in production of plant natural products and new-to-nature biopharmaceuticals in yeast

Thomas Perrot, Jillian Marc, Enzo Lezin, Nicolas Papon, Sébastien Besseau and Vincent Courdavault

Current Opinion in Biotechnology, 2024, 87, 103098
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The oleaginous yeast Rhodosporidium toruloides engineered for biomass hydrolysate-derived (E)-α-bisabolene production

Paul A. Adamczyk, Hee Jin Hwang, Ta-Hsuan Chang, Yuqian Gao, Edward E.K. Baidoo, Joonhoon Kim, Bobbie-Jo M. Webb-Robertson, Javier E. Flores, Kirch Czarina Quijano, Meagan C. Burnet, Nathalie Munoz, Eric Sundstrom, John M. Gladden and Di Liu

Metabolic Engineering, 2025, 90, 92
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Combinatorial metabolic engineering of Yarrowia lipolytica for high-level production of the plant-derived diterpenoid sclareol

Jiang Chen, Longzheng Huang, Bang-Ce Ye and Ying Zhou

Microb Cell Fact, 2025, 24
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Yeast species resource exploration and application in cell factories

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Synthetic and Systems Biotechnology, 2026, 13, 376
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Building a yeast cell factory for green biomanufacturing of (R)-(+)-γ-decalactone: A natural peach-like aroma compound

Yizi Yu, Kaifeng Wang, Tao Sun, Shushu Li, Ying Zhou, Mei-Li Sun, Lu Lin, Rodrigo Ledesma-Amaro and Xiao-Jun Ji

Chemical Engineering Journal, 2026, 535, 175287
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Engineering a versatile yeast platform for sesquiterpene production from glucose or methanol

Linhui Gao, Kun Zhang, Yiwei Shen, Peng Cai and Yongjin J. Zhou

Biotechnology Journal, 2024, 19
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Stress-driven regulation of cellular robustness for improving terpenoid production in Ogataea polymorpha

Song Yang, Yongjin Zhou and Jiaoqi Gao

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Peroxisome-based metabolic engineering for biomanufacturing and agriculture

Shuyan Song, Cuifang Ye, Yijun Jin, Huaxin Dai, Jianping Hu, Jiazhang Lian and Ronghui Pan

Trends in Biotechnology, 2024, 42, 1161
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Enhanced Expression of CsCCD2 Enables Highly Efficient Crocetin Production in Yarrowia lipolytica

Guiping Guo, Huibin Chen, Hailin Wang, Guilin Zhang, Xiaodan Fu, Man Yuen Lee, Yun-Chung Leung, Ningyang Li and Zhen Liu

J. Agric. Food Chem., 2026, 74, 13609
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Biosynthetic pathway redesign in non-conventional yeast for enhanced production of cembratriene-ol

Lihua Zhang, Cheng Fan, Haiquan Yang, Yuanyuan Xia, Wei Shen and Xianzhong Chen

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Efficient synthesis of squalene by cytoplasmic-peroxisomal engineering and regulating lipid metabolism in Yarrowia lipolytica

Yang Ning, Mengsu Liu, Ziyun Ru, Weizhu Zeng, Song Liu and Jingwen Zhou

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Synthetic Biology of Terpenoid and Flavonoid Natural Food Additives: Research Progress and Future Challenges

Yue Zhang, Xuemi Hao, Longshan Zhao, Li Xiang and Caixia Wang

J. Agric. Food Chem., 2025, 73, 27836
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Multiple Strategies Enhance 7-Dehydrocholesterol Production from Kitchen Waste by Engineered Yarrowia lipolytica

Tianyu Dong, Xiao Zhou, Zheng-Jie Hou, Yujie Shu, Mingdong Yao, Zhi-Hua Liu, Jing-Sheng Cheng, Wenhai Xiao and Ying Wang

J. Agric. Food Chem., 2025, 73, 693
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Biosynthesis Progress of High-Energy-Density Liquid Fuels Derived from Terpenes

Jiajia Liu, Man Lin, Penggang Han, Ge Yao and Hui Jiang

Microorganisms, 2024, 12, 706
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Enhanced Production of Santalols by Engineering the Cytochrome P450 Enzyme to the Peroxisomal Surface in Yeast

Dong Wang, Wenhao Li, Xiaochen Ma, Rongsheng Li, Tingting Yang, Rui Li, Yuanyuan Han, Ziwei Li, Xueli Zhang and Zhubo Dai

J. Agric. Food Chem., 2025, 73, 20307
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Transportation engineering for enhanced production of plant natural products in microbial cell factories

Yimeng Zuo, Minghui Zhao, Yuanwei Gou, Lei Huang, Zhinan Xu and Jiazhang Lian

Synthetic and Systems Biotechnology, 2024, 9, 742
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Genetic Engineering of Yarrowia lipolytica for 1,8-cineole production: A sustainable approach

Krutika Bhoir, Gunjan Prakash and Annamma Odaneth

Enzyme and Microbial Technology, 2025, 189, 110659
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Construction of Yarrowia lipolytica Capable of Degrading Alkanes and Tolerating High-Salt Stress

Xiaoqian Zhu, Shanshan Wang, Zhibei Cao, Mingzhu Ding and Yingjin Yuan

ACS Sustainable Chem. Eng., 2025, 13, 11868
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Metabolic engineering of Pichia pastoris for overproduction of cis-trans nepetalactol

Cuifang Ye, Mengxin Li, Jucan Gao, Yimeng Zuo, Feng Xiao, Xiaojing Jiang, Jintao Cheng, Lei Huang, Zhinan Xu and Jiazhang Lian

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Engineering Komagataella phaffii for citric acid production through carbon-conserving supply of acetyl-CoA

Evelyn Vásquez Castro, Özge Ata, Matthias G. Steiger, Tim Causon and Diethard Mattanovich

Metabolic Engineering, 2025, 89, 47
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Metabolic engineering of Yarrowia lipolytica to produce menaquinone-7

Yeqiao Shen, Xuezhen Wang, Shoubo Zuo, Zhongmin Tang, Zhengjun Xiong, Jie Xiong and Huili Zhang

Process Biochemistry, 2025, 157, 101
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Compartment engineering in yeast: a path to increased biochemical production

Yuyang Wang, Liyan Cao, Lanxin Rong, Chen Ding, Chang Liu, Qingqing Ye, Qingeng Huang, Cui-ying Zhang, Ning Xu, Jiwei Mao, Jee Loon Foo and Aiqun Yu

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Production of the terpenoid-based biofuel α-bisabolene by metabolically engineered Corynebacterium glutamicum

Basak Atas Erden, Jan Seeger, Fatma Gizem Avci, Volker F. Wendisch and Berna Sariyar Akbulut

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Separation strategies of terpenoids from microbial fermentation broths

Xuedong Chen, Guoqiang Chen, Lijuan Liu, Weihong Liao and Haibo Zhang

Trends in Food Science & Technology, 2025, 162, 105098
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Peroxisome engineering in yeast: Advances, challenges, and prospects

Cuifang Ye, Xiaoqian Li, Tao Liu, Shiyu Li, Mengyu Zhang, Yao Zhao, Jintao Cheng, Guiling Yang and Peiwu Li

Biotechnology Advances, 2026, 86, 108747
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Metabolic Engineering for Squalene Production: Advances and Perspectives

Liang Chai, Jiaxin Che, Qingsheng Qi and Jin Hou

J. Agric. Food Chem., 2024, 72, 27715
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Production of the Sesquiterpene Bisabolene From One‐ and Two‐Carbon Compounds in Engineered Methanosarcina acetivorans

Andrea Mentrup, Luca V. Scheitz, Theo Wallenfang and Michael Rother

Microbial Biotechnology, 2025, 18
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Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols

Mengyuan Li, Ruiqi Chen, Jianjun Qiao, Weiguo Li and Hongji Zhu

Biomolecules, 2025, 15, 664
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A review on squalene production by engineered yeasts: Current advances and perspectives

Peng-Cheng Hu, La-Mei Ding, Qiao-Qin Zhao, Mao-Cheng Tang, Pei-Fang Xiao, Chong Wang, Xiang-Yang Lu, Yun Tian and Hu-Hu Liu

Biotechnology Advances, 2026, 87, 108792
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Recent developments of oleaginous yeasts toward sustainable biomanufacturing

Paul A Adamczyk, Tian Jiang, Karuna Jetty, Vijaydev Ganesan and Di Liu

Current Opinion in Biotechnology, 2025, 93, 103297
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Renewable Diesel Fuel Prepared by the Isomerization and Hydrogenation of Biosynthetic Farnesene

Christopher J. Walkling, Karan R. Doppalapudi, Derek D. Zhang and Benjamin G. Harvey

Energy Fuels, 2025, 39, 8495
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Engineering and characterization of small-molecule transporters for cell factories

Yuesheng Zhang, Douglas B. Kell and Irina Borodina

Trends in Biotechnology, 2025
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Engineering strategies for producing medium-long chain dicarboxylic acids in oleaginous yeasts

Xin Wang, Mei-Li Sun, Lu Lin, Rodrigo Ledesma-Amaro, Kaifeng Wang and Xiao-Jun Ji

Bioresource Technology, 2025, 430, 132593
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Advances in multi-enzyme co-localization strategies for the construction of microbial cell factory

Qi Guo, Yu-Xin Yang, Dong-Xun Li, Xiao-Jun Ji, Na Wu, Yue-Tong Wang, Chao Ye and Tian-Qiong Shi

Biotechnology Advances, 2024, 77, 108453
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