Insights into the role of Nrf2 in vitiligo pathogenesis: a target for herbal medicine

Abdel Qawasmeh, Mohammad Qaisiya, Areej Ishnaiwer, Dana Khdour, Shoroq Shawar, Seema Fallah, Duha Hashlamon, Hanadi Sinokrot and Alaa Kharaiwesh

Front. Nat. Prod., 2025, 4
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USP38 exacerbates myocardial injury and malignant ventricular arrhythmias after ischemia/reperfusion by promoting ferroptosis through the P53/SLC7A11 pathway

Yang Gong, Hongjie Yang, Tao Chen, Jingjing Zhang, Bin Kong, Wei Shuai and He Huang

International Immunopharmacology, 2025, 145, 113727
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Carnosic acid serves as a dual Nrf2 activator and PTEN/AKT suppressor to inhibit traumatic heterotopic ossification

Donglei Wei, Dezhi Song, Hui Wang, Yuangang Su, Jiamin Liang, Jiake Xu, Jinmin Zhao and Qian Liu

Stem Cell Res Ther, 2025, 17
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Thiolutin Alleviates Cardiotoxic Effects of Doxorubicin by Suppressing NLRP3 Inflammasome in the Mouse Model

Wenyuan Cai, Tingting Teng, Xiaoyan Wang, Baihong Li, Xin Gu and Yafeng Zhou

Cardiovasc Toxicol, 2025, 25, 182
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Carnosic acid inhibits integrin expression and prevents pulmonary metastasis of melanoma

Sachi Shibata, Kohei Yamada and Shigeyuki Kon

Bioscience, Biotechnology, and Biochemistry, 2025, 89, 284
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Protective effects of Melissa officinalis ethanolic extract on doxorubicin-induced cardiotoxicity in a rat model

Jelena N. Terzic, Lazar Z. Veljkovic, Vladimir L.j. Jakovljevic, Jovana N. Novakovic, Jasmina Z. Sretenovic, Maja D. Muric, Aleksandar G. Kocovic and Isidora M. Milosavljevic

Can. J. Physiol. Pharmacol., 2026, 104, 1
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Targeting cardiovascular risk factors with eugenol: an anti-inflammatory perspective

Sushma Devi, Samrat Chauhan, Ashi Mannan and Thakur Gurjeet Singh

Inflammopharmacol, 2024, 32, 307
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Micafungin protects mouse heart against doxorubicin-induced oxidative injury via suppressing MALT1-dependent k48-linked ubiquitination of Nrf2

Li-Qun Lu, Ming-Rui Li, Lin-Lu Huang, Yan-Xi Che, Ya-Nan Qi, Xiu-Ju Luo and Jun Peng

Chemico-Biological Interactions, 2024, 400, 111179
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The therapeutic effect and mechanism of carnosic acid in Aspergillus fumigatus keratitis

Menghui Chi, Lingwen Gu, Lina Zhang, Jing Lin, Qian Wang, Xueyun Fu, Xue Tian, Ziyi Wang, Bing Yu, Wenyao Liu, Cui Li and Guiqiu Zhao

Experimental Eye Research, 2025, 254, 110338
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Carnosic acid attenuates ventilator-induced diaphragmatic dysfunction via activation of the Nrf2/HO-1 pathway

Zilin Liu, Qian Yu, Xianlong Zhou, Haoli Ma, Renxiong Wei and Jian Xia

International Immunopharmacology, 2026, 168, 115926
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An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity

Sa Liu, Jiaqin Liu, Nan Su, Shanshan Wei, Ning Xie, Xiangyun Li, Suifen Xie, Jian Liu, Bikui Zhang, Wenqun Li and Shengyu Tan

Cardiovasc Drugs Ther, 2025, 39, 517
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Dibenzazepine, a γ-Secretase Enzyme Inhibitor, Protects Against Doxorubicin-Induced Cardiotoxicity by Suppressing NF-κB, iNOS, and Hes1/Hey1 Expression

Amira M. Badr, Hind N. Alotaibi and Naglaa El-Orabi

Inflammation, 2024, 48, 557
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Exploring the therapeutic potential of bioactive compounds from selected plant extracts of Mediterranean diet constituents for cardiovascular diseases: A review of mechanisms of action, clinical evidence, and adverse effects

Mateu Anguera-Tejedor, Gabino Garrido, Bárbara B. Garrido-Suárez, Alejandro Ardiles-Rivera, Àngel Bistué-Rovira, Francesc Jiménez-Altayó and René Delgado-Hernández

Food Bioscience, 2024, 62, 105487
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A novel approach to the prevention and management of chemotherapy-induced cardiotoxicity: PANoptosis

Chenchen Meng, Yali Wang, Tiantian Zheng, Zheng Rong, Zhengtian Lv, Chenxia Wu, Xinbin Zhou and Wei Mao

Chemico-Biological Interactions, 2025, 407, 111379
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Nrf2: a dark horse in doxorubicin-induced cardiotoxicity

Xiaopeng Zhao, Zheng Tian, Mingli Sun and Dan Dong

Cell Death Discov., 2023, 9
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Serinc2 deficiency exacerbates sepsis-induced cardiomyopathy by enhancing necroptosis and apoptosis

Shan Hu, Min Huang, Shuai Mao, Manqi Yang, Hao Ju, Zheyu Liu, Mian Cheng and Gang Wu

Biochemical Pharmacology, 2023, 218, 115903
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Sarmentosin alleviates doxorubicin-induced cardiotoxicity and ferroptosis via the p62-Keap1-Nrf2 pathway

Zhihui Lin, Chang Wu, Dongyan Song, Chenxi Zhu, Bosen Wu, Jie Wang and Yangjing Xue

Redox Report, 2024, 29
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Engineering materials for pyroptosis induction in cancer treatment

Jiayi Liu, Taili Chen, XianLing Liu, ZhiHong Li and Yong Zhang

Bioactive Materials, 2024, 33, 30
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Targeting the NLRP3 by Natural Compounds: Therapeutic Strategies to Mitigate Doxorubicin-Induced Cardiotoxicity

Dareuosh Shackebaei, Kheirollah Yari, Nader Rahimi, Sara Gorgani and Fatemeh Yarmohammadi

Cell Biochem Biophys, 2025, 83, 2779
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Carnosic Acid Directly Targets STING C‐Terminal Tail to Improve STING‐Mediated Inflammatory Diseases

Wenqing Mu, Guang Xu, Ling Li, Jincai Wen, Ye Xiu, Jia Zhao, Tingting Liu, Ziying Wei, Wei Luo, Huijie Yang, Zhixin Wu, Xiaoyan Zhan, Xiaohe Xiao and Zhaofang Bai

Advanced Science, 2025, 12
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Boswellic Acid and Carnosine Ameliorate Vanadyl-Sulfate-Induced Renal Damage via Regulating Nrf2/HO-1 and PI3K/AKT Pathways

Ghada M. Gad, Nahla S. Kotb and Khalid S. Hashem

Biol Trace Elem Res, 2025, 204, 1820
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NLRP3 inflammasome as a therapeutic target in doxorubicin-induced cardiotoxicity: role of phytochemicals

Xiao-Peng Zhao, Lian Duan, Qian-Ru Zhao, Xing Lv, Nai-Yuan Tian, Sheng-Lei Yang and Kun Dong

Front. Pharmacol., 2025, 16
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Berberine ameliorates iron levels and ferroptosis in the brain of 3 × Tg-AD mice

Xinlu Li, Jianfeng Chen, Wennuo Feng, Chao Wang, Minyu Chen, Yifan Li, Jinghong Chen, Xinwei Liu, Qiong Liu and Jing Tian

Phytomedicine, 2023, 118, 154962
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Ferroptosis: Latest evidence and perspectives on plant‐derived natural active compounds mitigating doxorubicin‐induced cardiotoxicity

Boyu Wang, Jiameng Wang, Changxing Liu, Chengjia Li, Tianwei Meng, Jia Chen, Qingnan Liu, Wang He, Zhiping Liu and Yabin Zhou

J of Applied Toxicology, 2025, 45, 135
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Doxorubicin-Induced Cardiotoxicity: A Comprehensive Update

Vasvi Bhutani, Fahimeh Varzideh, Scott Wilson, Urna Kansakar, Stanislovas Jankauskas and Gaetano Santulli

JCDD, 2025, 12, 207
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The mechanism and therapeutic strategies in doxorubicin-induced cardiotoxicity: Role of programmed cell death

Yanzhao Li, Jing Yan and Pingzhen Yang

Cell Stress and Chaperones, 2024, 29, 666
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Pyroptosis: Mechanisms and links with diabetic cardiomyopathy

Pan Liu, Zhengdong Zhang, Huizhen Chen and Qiu Chen

Ageing Research Reviews, 2024, 94, 102182
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Butyrate protects against myocardial ischemia injury and cardiomyocyte pyroptosis by inhibiting MALT1-mediated Nrf2 ubiquitination and degradation

Peipei Zhang, Youli Su and Yi Cheng

J Mol Histol, 2025, 56
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Dehydroevodiamine Alleviates Doxorubicin‐Induced Cardiomyocyte Injury by Regulating Neuregulin‐1/ErbB Signaling

Song Jie, Guo Wenying, Sun Lebo and Vivek Pandey

Cardiovascular Therapeutics, 2024, 2024
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CARD11-BCL10-MALT1 Complex-Dependent MALT1 Activation Facilitates Myocardial Oxidative Stress in Doxorubicin-Treated Mice via Enhancing k48-Linked Ubiquitination of Nrf2

Li-Qun Lu, Ming-Rui Li, Xu-Yan Liu, Dan Peng, Hong-Rui Liu, Xiao-Jie Zhang, Xiu-Ju Luo and Jun Peng

Antioxidants & Redox Signaling, 2025, 42, 115
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Yiqi Wenyang formula ameliorates mitochondrial damage in doxorubicin-induced cardiotoxicity by activating the SIRT1/PGC-1α signaling pathway

Zitian Liu, Xiaoming Wang, Xiaonian Zhou, Jixu Li, Qiuyan Luo, Shujie Zhang, Yao Zhu and Weimin Jiang

Fitoterapia, 2026, 191, 107184
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Natural products and ferroptosis: A novel approach for heart failure management

Zeyu Zhang, Zhihua Yang, Shuai Wang, Xianliang Wang and Jingyuan Mao

Phytomedicine, 2025, 142, 156783
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Germacrone mitigates cardiac remodeling by regulating PI3K/AKT-mediated oxidative stress, inflammation, and apoptosis

Zhao Fang, Feierkaiti Yushanjiang, Guangji Wang, Xiaoxin Zheng and Xuejun Jiang

International Immunopharmacology, 2023, 124, 110876
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Traditional Chinese medicine protects against doxorubicin cardiotoxicity via epigenetic modification and beyond

Jingquan Zhou, Huan Liu, Feng Jiang, Xiyong Yu, Panxia Wang and Xiaoqian Wu

Phytomedicine, 2025, 145, 157020
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Poria cocos Polysaccharides Attenuate Cardiac Injury by Inhibiting CaMKII-Mediated P38/NF-κB/NLRP3 Signaling Pathway to Reduce Sepsis-Induced Apoptosis and Inflammation

Manqi Yang, Bo Cui, Shan Hu, Hao Ju, Zheyu Liu, Min Huang, Shuijing He, Mian Cheng, Tao Liu and Gang Wu

Am. J. Chin. Med., 2025, 53, 1865
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Doxorubicin-mediated cardiac dysfunction: Revisiting molecular interactions, pharmacological compounds and (nano)theranostic platforms

Xiaofeng Li

Environmental Research, 2023, 234, 116504
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Tirzepatide alleviates doxorubicin-induced cardiotoxicity via inhibiting HRD1-mediated Nrf2 ubiquitination

Dan Yang, Yang-Hao Chen, Yan-Kun Chen, Ya-Lin Zeng and Zhi-Yu Ling

Cardiovascular Research, 2025, 121, 1865
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Bergapten mitigates doxorubicin-induced cardiotoxicity via NOX4/Nrf2/HO-1 axis: Insights from in vitro and in vivo models

Bijoy Krishna Banik, Sourav Kundu, Swati Tirunal Achary, Bedilipi Das, Shobhit Verma, Madhav Nilakanth Mugale and Bidya Dhar Sahu

Free Radical Biology and Medicine, 2026, 243, 534
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