Alexandre Simon, Virgile Rouffeteau, Camilla Acconcia, Sylvestre P. J. T. Bachollet, Jérémy Forté, Mariateresa Giustiniano, Laurence Grimaud and Maxime R. Vitale

Org. Chem. Front., 2025, 12, 3551
DOI: 10.1039/D5QO00352K

Recent advances in dual photoredox/nickel catalyzed alkene carbofunctionalised reactions

Anilkumar Kommoju, Kattamuri Snehita, Kandi Sowjanya, Saratchandra Babu Mukkamala and Kishor Padala

Chem. Commun., 2024, 60, 8946
DOI: 10.1039/D4CC02914C

Investigation of the activation mode of vinylarene in Giri's Ni-catalyzed vinylarene intermolecular 1,2-alkylarylation cross-coupling: a theoretical study

Song Liu, Dianmin Zhang, Xiaoqing Zhang, Yuyan Cheng and Hong Deng

Org. Chem. Front., 2023, 10, 4359
DOI: 10.1039/D3QO00851G

Recent developments in nickel-catalyzed asymmetric cyclization and cycloaddition of carbonyl-alkynes, cyano-alkynes, and enynes

Jun Yan, Min Shi and Yin Wei

Chem. Commun., 2023, 59, 4405
DOI: 10.1039/D3CC00520H

Base-mediated C–B bond activation of benzylic boronate for the rapid construction of β-silyl/boryl functionalized 1,1-diarylalkanes from aromatic alkenes

Liuzhou Gao, Xinyi Liang, Linke He, Guoao Li, Shengda Chen, Jia Cao, Jing Ma, Guoqiang Wang and Shuhua Li

Chem. Sci., 2023, 14, 11881
DOI: 10.1039/D3SC03666A

Photocatalytic 1,3-difluoroalkylcarboxylation of alkenes by triple kinetic-controlled radical self-ordering

Hong Fu, Zuo-Shuai Wang, Si-Jia Li, Lin-Yuan Zhu, Xiao-Jian Wang, Hong-Chen Wang and Bing Han

Chem. Sci., 2025, 16, 5849
DOI: 10.1039/D4SC08607D

Ni-catalyzed enantioselective three-component reductive alkylacylation of alkenes: modular access to structurally complex α-amino ketones

Jichao Xiao, Tingting Jia, Shuang Chen, Mengxiao Pan and Xingwei Li

Chem. Sci., 2024, 15, 15489
DOI: 10.1039/D4SC04561K

Photocatalytic multicomponent alkene dicarbofunctionalization via PCET/nickel dual catalysis

Yeersen Patehebieke, Victoria Jansson, Jakob Öberg and Carl-Johan Wallentin

Chem. Sci., 2026
DOI: 10.1039/D6SC00382F

Photoinduced copper-catalyzed three-component alkylarylation of alkenes involving C–S bond cleavage of sulfonium salts

Hui Chen, Xuan Shang, Nan Jiang, Quan Zhou, Ke-Wen Tang, Long-Jin Zhong and Yu Liu

Org. Chem. Front., 2025, 12, 1498
DOI: 10.1039/D4QO01740D

Directed, nickel-catalyzed 1,2-alkylsulfenylation of alkenyl carbonyl compounds

Zi-Qi Li, Wen-Ji He, Hui-Qi Ni and Keary M. Engle

Chem. Sci., 2022, 13, 6567
DOI: 10.1039/D2SC01563C

N, N-Difluoroarylsulfonamides: A Reagent for Chemodivergent Trifunctionalization of Unactivated Alkenes to Construct Quinoline Isosteres

Lin-Yu Lu, Xiao-Xiao Sun, Hongwei Zhang, Quan-Xin Li, Jianzheng Gao, Huabin Zhang, Jingbin Zeng, Yuan-Qing Xu, Shengnan Jin, HuiJuan Wang, Shao-Fei Ni and Zhong-Yan Cao

ACS Catal., 2026, 16, 806
DOI: 10.1021/acscatal.5c07781

Synthesis of Vicinal Carbocycles by Intramolecular Nickel-Catalyzed Conjunctive Cross-Electrophile Coupling Reaction

Kirsten A. Hewitt, Claire A. Herbert and Elizabeth R. Jarvo

Org. Lett., 2022, 24, 6093
DOI: 10.1021/acs.orglett.2c02481

Nickel‐Catalyzed Cross‐Electrophile 1,2‐Silyl‐Arylation of 1,3‐Dienes with Chlorosilanes and Aryl Bromides

Qiu‐Quan Pan, Liangliang Qi, Xiaobo Pang and Xing‐Zhong Shu

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202215703

Selective Hydrofunctionalization of Alkenyl Fluorides Enabled by Nickel-Catalyzed Hydrogen Atoms and Group Transfer: Reaction Development and Mechanistic Study

Fan Chen, Qianwei Zhang, Yingying Li, Zhi-Xiang Yu and Lingling Chu

J. Am. Chem. Soc., 2024
DOI: 10.1021/jacs.4c01506

Enantioselective Synthesis of Benzylic Boronic Esters via Photoredox/Nickel-Catalyzed Multicomponent Cross-Couplings

Xu He, Enxue Shi and Junhua Xiao

Org. Lett., 2024, 26, 9728
DOI: 10.1021/acs.orglett.4c03544

Access to Axially Chiral Vinyl Sulfilimines via Copper‐Catalyzed Enantioselective Radical Relay Trifluoromethyl‐Sulfilimination of Terminal Alkynes

Wei Wang, Qi Yang, Yunfei Yao, Lan Hu, Mingwei Jiang, Juan Tan, Guangfan Zheng, Jichao Xiao and Xingwei Li

Angew Chem Int Ed, 2026, 65
DOI: 10.1002/anie.202523530

Copper‐Catalyzed[3 + 2 + 1] Cycloaddition of Alkenes with Benzoquinones and Dicarbonyl Compounds via Tandem Oxidative Dicarbofunctionalization/Cyclization Sequence

Tianxing Du, Song Li, Yunfei He, Huan Long, Xigong Liu, Hai‐Bei Li and Lei Liu

Chin. J. Chem., 2022, 40, 1681
DOI: 10.1002/cjoc.202200113

Asymmetric 1,2-oxidative alkylation of conjugated dienes via aliphatic C–H bond activation

Lian-Feng Fan, Rui Liu, Xiao-Yun Ruan, Pu-Sheng Wang and Liu-Zhu Gong

Nat. Synth, 2022, 1, 946
DOI: 10.1038/s44160-022-00172-8

N-Heterocyclic Carbene-Catalyzed 1,4-Alkylacylation of 1,3-Enynes

Yuxing Cai, Jiean Chen and Yong Huang

Org. Lett., 2021, 23, 9251
DOI: 10.1021/acs.orglett.1c03601

Synthesis and Reaction of Pentafluorosulfanyl Chloride (SF5Cl)

Jia‐Yi Shou and Feng‐Ling Qing

Chin. J. Chem., 2025, 43, 3033
DOI: 10.1002/cjoc.70217

Computational and Mechanistic Studies of Pd-Catalyzed Alkene Carboacylation via Ester C–O Bond Activation

Melisa Alkan, Haley K. Banovetz, Mark S. Gordon and Levi M. Stanley

ACS Catal., 2023, 13, 9766
DOI: 10.1021/acscatal.3c01405

Strategies and Mechanisms of First-Row Transition Metal-Regulated Radical C–H Functionalization

Xinghua Wang, Jing He, Ya-Nan Wang, Zhenyan Zhao, Kui Jiang, Wei Yang, Tao Zhang, Shiqi Jia, Kangbao Zhong, Linbin Niu and Yu Lan

Chem. Rev., 2024, 124, 10192
DOI: 10.1021/acs.chemrev.4c00188

Carbon-centered radical capture at nickel(II) complexes: Spectroscopic evidence, rates, and selectivity

Qiao Lin, Ethan H. Spielvogel and Tianning Diao

Chem, 2023, 9, 1295
DOI: 10.1016/j.chempr.2023.02.010

Copper-Catalyzed anti-Selective Radical 1,2-Alkylarylation of Terminal Alkynes

Jun-Bin Tang, Jun-Qian Bian, Yu-Shuai Zhang, Yong-Feng Cheng, Han-Tao Wen, Zhang-Long Yu, Zhong-Liang Li, Qiang-Shuai Gu, Guo-Qiang Chen and Xin-Yuan Liu

Org. Lett., 2022, 24, 2536
DOI: 10.1021/acs.orglett.2c00692

Regio- and enantioselective hydrofluorination of internal alkenes via nickel-catalyzed hydrogen atom transfer

Fan Chen, Xiaoyu Zhao, Weihang Miao, Yingying Li, Ye Yuan and Lingling Chu

Chinese Chemical Letters, 2025, 36, 110239
DOI: 10.1016/j.cclet.2024.110239

Ruthenium-catalyzed alkylarylation of alkenes via para-selective C−H functionalization of unprotected anilines

Xin-Juan Wang, Yao-Hang Cheng, Xin-Yan Lv, Li-Ye Liang, Guang-Hui An and Guang-Ming Li

Chinese Chemical Letters, 2025, 112154
DOI: 10.1016/j.cclet.2025.112154

Copper‐Catalyzed Regioselective 1,4‐Phosphinoylcyanation of 1,3‐Enynes with Diarylphosphine Oxides and TMSCN

Yunhe Lv, Jinhui Xie, Weiya Pu, Xue Wang, Huanhuan Zhang, Xuerui Li, Yan Liu, Fei Chen and Yunfeng Xu

Adv Synth Catal, 2023, 365, 4170
DOI: 10.1002/adsc.202300824

Enantioselective construction of C-B axially chiral alkenylborons by nickel-catalyzed radical relayed reductive coupling

Weihua Qiu, Rencai Tao, Yong He, Yao Zhou, Kai Yang and Qiuling Song

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-54597-0

Escaping from directing groups: Enantioselective C–C bond construction from unactivated olefins

Hongyu Zhong and Bill Morandi

Science Bulletin, 2024, 69, 290
DOI: 10.1016/j.scib.2023.11.044

Ni-Catalyzed Reductive Arylalkenylation of Alkynes for the Selective Synthesis of Polysubstituted Naphthalenes

Meng-Qiang Zeng, Ke-Xin Feng, Bo-Lun Hu, Hai-Yong Tu and Xing-Guo Zhang

Org. Lett., 2022, 24, 5386
DOI: 10.1021/acs.orglett.2c02068

Highlights of Pd-Catalyzed Reactions of Alkynes Involving C–H Functionalization: Synthesis of Acyclic, Carbo-, and Heterocyclic Compounds Installed with Alkyne Unit

Subhankar Bodak, Prashant Shukla, Amit Kumar and Srinivasarao Arulananda Babu

Synthesis, 2026
DOI: 10.1055/a-2796-9980

Photocatalytic vinyl radical-mediated multicomponent 1,4-/1,8-carboimination across alkynes and olefins/(hetero)arenes

Shan-Shan Li, Yu-Shi Jiang, Xue-Ling Luo, Xuming Ran, Yuqiang Li, Dong Wu, Cheng-Xue Pan and Peng-Ju Xia

Sci. China Chem., 2024, 67, 558
DOI: 10.1007/s11426-023-1812-x

Recent Advances in Visible Light Induced Radical 1,2-Functionalization of Alkynes

Kangkui Li, Xianyang Long, Yue Huang and Shifa Zhu

Acta Chimica Sinica, 2024, 82, 658
DOI: 10.6023/A24030090

Recent advances in photoredox/transition metal-catalyzed sulfonylation using sodium sulfinates

Da-Liang Zhu, Jie Li, David J. Young, Yanqing Wang and Hong-Xi Li

Tetrahedron, 2025, 184, 134733
DOI: 10.1016/j.tet.2025.134733

Visible-Light-Induced Photoredox 1,2-Dialkylation of Styrenes with α-Carbonyl Alkyl Bromides and Pyridin-1-ium Salts

Chong-Hui Xu, Gui-Fen Lv, Jing-Hao Qin, Xin-Hua Xu and Jin-Heng Li

J. Org. Chem., 2024, 89, 281
DOI: 10.1021/acs.joc.3c02018

N-heterocyclic nitrenium-catalyzed photoreductive radical-polar crossover for alkene dicarbofunctionalization

Youfeng Han, Beibei Zhang, Zhixiang Wang and Xiangyu Chen

Green Synthesis and Catalysis, 2026, 7, 175
DOI: 10.1016/j.gresc.2024.03.002

Phosphine-Based Porous Organic Polymer-Stabilized Palladium Nanoparticle Catalyst for the Regioselective Synthesis of Indenones

Pramod Kumar, Ayan Jati and Biplab Maji

Org. Lett., 2025, 27, 2191
DOI: 10.1021/acs.orglett.5c00299

One metal two tasks: Reentering the catalytic ending PdII-H for the relay-catalytic cycle for dicarbonylation of amines

Chang-Sheng Kuai, Bing-Hong Teng, Rui Lai, Yingying Zhao, Guohui Li and Xiao-Feng Wu

Journal of Catalysis, 2023, 426, 368
DOI: 10.1016/j.jcat.2023.08.006

Photochemistry‐Enabled Nitrogen‐Assisted Organostibines as an Efficient Alkyl Radical Precursor: Mechanistic Insights and Synthetic Applications

Niu Tang, Xinyu Li, Chenghan Li, Liyuan Le, Yifeng Ou, Shuangfeng Yin and Renhua Qiu

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202514967

Direct synthesis of unprotected aryl C-glycosides by photoredox Ni-catalysed cross-coupling

Chen Zhang, Shi-Yang Xu, Hao Zuo, Xia Zhang, Qiu-Di Dang and Dawen Niu

Nat. Synth, 2023, 2, 251
DOI: 10.1038/s44160-022-00214-1

Copper‐Catalyzed Regiodivergent Asymmetric Difunctionalization of Terminal Alkynes

Simin Wang, Kexin Chen, Junbo Niu, Xiaobing Guo, Xiuping Yuan, Jianjun Yin, Bo Zhu, Dazhen Shi, Wei Guan, Tao Xiong and Qian Zhang

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202410833

Nickel‐Catalyzed Regioselective Intermolecular Dialkylation of Alkenylarenes: Generation of Two Vicinal C(sp3)−C(sp3) Bonds Across Alkenes**

Daniel M. Lux, Vivek Aryal, Doleshwar Niroula and Ramesh Giri

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202305522

Iron-Catalyzed Site- and Regioselective 1,2-Azidoamidations of 1,3-Dienes

Zhen-Yao Dai, Ilia A. Guzei and Jennifer M. Schomaker

Org. Lett., 2024, 26, 269
DOI: 10.1021/acs.orglett.3c03947

Visible‐Light Driven Copper‐Catalyzed Oxidative Alkylation of Styrenes with Sulfonium Salts and Alcohol or Acids

Long‐Jin Zhong, Shu‐Zheng Ou, Peng‐Fei Huang, Ke‐Wen Tang, Quan Zhou and Yu Liu

Adv Synth Catal, 2026, 368
DOI: 10.1002/adsc.70314

Chemo-, regio- and stereoselective access to polysubstituted 1,3-dienes via Nickel-catalyzed four-component reactions

Shanglin Chen, Ya-Nan Wang, Jinhui Xie, Wangyang Li, Mingxing Ye, Xingxing Ma, Kai Yang, Shijun Li, Yu Lan and Qiuling Song

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-49870-1

Cine‐Reductive Carboboration of Alkenyl Electrophiles via Iron Catalysis

Adong Qiao, Shasha Geng, Xianrong Chen, Jinping Yuan, Yun He, Mei Bai and Zhang Feng

Angewandte Chemie, 2026, 138
DOI: 10.1002/ange.202525623

Photoinduced Three-Component Carboarylation of Unactivated Alkenes with Protic C(sp3)–H Feedstocks

Yang Hong, Meng-Yuan Dong, Dong-Sheng Li and Hong-Ping Deng

Org. Lett., 2022, 24, 7677
DOI: 10.1021/acs.orglett.2c03247

Divergent and Selective Light Alkene Cross‐Coupling

Zi‐Chao Wang, Jia‐Wen Zhang, Ming Joo Koh and Shi‐Liang Shi

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202310203

Photocatalytic selective 1,4-oxyimination/diamination across C=C and N=N bonds to access structurally diverse N-N-N triazane derivatives

Yu-Shi Jiang, Dan-Na Chen, Huan Jiang and Peng-Ju Xia

Green Synthesis and Catalysis, 2024
DOI: 10.1016/j.gresc.2024.07.003

Chemo- and Regioselective Nickel-Catalyzed Reductive 1,4-Alkylarylation of 1,3-Enynes through an L2NiAr Intermediate

Ji Hwan Jeon, Gun Ha Kim, Ho Seung Lee, Da Hye Kim, Soochan Lee, Wonyoung Choe, Byunghyuck Jung, Jan-Uwe Rohde and Sung You Hong

ACS Catal., 2024, 14, 8996
DOI: 10.1021/acscatal.4c01189

Photoredox/Nickel‐Cocatalyzed Asymmetric C–O and C–S Couplings for Atroposelective Synthesis of N‐Heterobiaryls

Tian‐Zhen Li, Cheng‐Cheng Tian, Wei Chen, Zi‐Yun Zou, Jia‐Liang Yang, Fang‐Xi Liu, Xinyao Li, Hong‐Hao Zhang and Feng Shi

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202516584

Neutral Chalcogen Bonding Enabled Photoinduced Cross‐Electrophile C—S/Se Coupling of Aryl Iodides via SRN1 Process

Yong‐Liang Tu, Xiang Li, Bei‐Bei Zhang, Gui‐Ying Fu, Ling Zhou, Wei Gong and Xiang‐Yu Chen

Chin. J. Chem., 2025, 43, 1299
DOI: 10.1002/cjoc.202401197

α‐Acylation of Alkenes by a Single Photocatalyst

Yuan‐Yuan Cheng, Hong‐Yu Hou, Yu Liu, Ji‐Xin Yu, Bin Chen, Chen‐Ho Tung and Li‐Zhu Wu

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202208831

Enantioselective reductive aryl-benzylation of alkenes by a nickel-titanium bimetallic system

Can Zhao, Zhaoliang Ge, Jinghui Hu, Hongjun Tian and Xiaoming Wang

Cell Reports Physical Science, 2023, 4, 101474
DOI: 10.1016/j.xcrp.2023.101474

An Efficient Three-Component Tandem Approach for the Synthesis of Imidazoheterocycle-Hydrazine Derivatives under Mild Conditions

Huijie Qiao, Liting Yang, Ya Chen, Jialin Wang, Wuxuan Sun, Haobo Dong and Yunwei Wang

Chinese Journal of Organic Chemistry, 2022, 42, 1188
DOI: 10.6023/cjoc202110015

Copper‐Catalyzed Enantioselective C(sp3)−SCF3 Coupling of Carbon‐Centered Benzyl Radicals with (Me4N)SCF3

Wei Zhang, Yu Tian, Xiao‐Dong Liu, Cheng Luan, Ji‐Ren Liu, Qiang‐Shuai Gu, Zhong‐Liang Li and Xin‐Yuan Liu

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202319850

Cooperative triple catalysis enables regioirregular formal Mizoroki–Heck reactions

Kun Liu, Dirk Leifert and Armido Studer

Nat. Synth, 2022, 1, 565
DOI: 10.1038/s44160-022-00101-9

Ni‐Catalyzed Linearizable Cyclization/Coupling with Detachable Silicon‐Oxygen Linker: Access to 1,2‐Oxasilolanes, 3‐Hydroxysilanes and 4‐Arylalkanols

Margaret G. Lakomy, Majji Shankar, Ava C. Del Rio and Ramesh Giri

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202404679

Organophotoredox/Ni-Cocatalyzed Allylation of Allenes: Regio- and Diastereoselective Access to Homoallylic Alcohols

Hui Xie and Bernhard Breit

ACS Catal., 2022, 12, 3249
DOI: 10.1021/acscatal.2c00464

Quinolinamide-Enabled Nickel-Catalyzed Regio- and Diastereoselective γ,δ-Arylalkylation of Nonactivated Alkenes

Lanlan Zhang, Lei Zhao, Yuqin Zhu and Chao Wang

Synlett, 2024, 35, 1121
DOI: 10.1055/a-2192-7085

anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis

Xian-Hua Pan, Chang-Xin Shi, Ya-Ping Hou, Li-Fang Wang, Rui-Qi Niu and Lei Guo

Org. Lett., 2024, 26, 9498
DOI: 10.1021/acs.orglett.4c03439

Late‐Stage Modification of Oligopeptides by Nickel‐Catalyzed Stereoselective Radical Addition to Dehydroalanine

Xiaoxu Qi, Subramanian Jambu, Yining Ji, Kevin M. Belyk, Nihar R. Panigrahi, Paramjit S. Arora, Neil A. Strotman and Tianning Diao

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202213315

Fe-Catalyzed Alkylazidation of α-Trifluoromethylalkenes: An Access to Quaternary Stereocenters Containing CF3 and N3 Groups

Shuai Liu, Lu Zhang, Liang Xu, Pin Gao, Xin-Hua Duan and Li−Na Guo

Org. Lett., 2023, 25, 1336
DOI: 10.1021/acs.orglett.3c00439

Ni-Catalyzed Reductive 1,2-Alkylarylation of Alkenes for the Synthesis of Spirocyclic γ-Lactams

James W. Pearson, Teh Ren Hou, Jelena Golijanin, Patricia I. Stewart, Eun Seo Choi, Alexis L. Gabbey, Michael S. West and Sophie A. L. Rousseaux

Org. Lett., 2024, 26, 5560
DOI: 10.1021/acs.orglett.4c01981

Lewis Acid Promoted Vicinal Oxytrifluoromethylselenolation of Alkenes

Yang Li, Shangbiao Zhang, Yanan Wang, Yan Gao, Chao Chen and Zheliang Yuan

Org. Lett., 2023, 25, 3210
DOI: 10.1021/acs.orglett.3c00846

Enantioselective C–C cross-coupling of unactivated alkenes

Zi-Chao Wang, Xiaohua Luo, Jia-Wen Zhang, Chen-Fei Liu, Ming Joo Koh and Shi-Liang Shi

Nat Catal, 2023, 6, 1087
DOI: 10.1038/s41929-023-01037-9

Pd-catalyzed diastereoselective 1,1-diarylation of 1,1-disubstituted alkenes enabling the modular synthesis of 1,1,2,2-tetraarylethanes

Chengxi Zhang, Yang Xi, Jingping Qu and Yifeng Chen

Sci. China Chem., 2023, 66, 3539
DOI: 10.1007/s11426-023-1780-2

Iron-Catalyzed Regioselective Reductive Fluoroalkylalkenylation of Unactivated Alkenes

Siyu Wang, Bohao Guo, Tong Mu, Zhengli Liu, Yun He, Xiao-Song Xue and Zhang Feng

ACS Catal., 2024, 14, 1575
DOI: 10.1021/acscatal.3c05690

Nickel-Catalyzed Reductive anti-Arylative Cyclization of Alkynyl Enones with Aryl Halides

Denghong Yan, Shun Wen, Yunxin Xing, Jie Bu and Kun Shen

J. Org. Chem., 2024, 89, 2223
DOI: 10.1021/acs.joc.3c02120

Ball-milling-enabled nickel-catalyzed radical relayed reductive cross-coupling

Chunying Fan, Bobo Wang, Tianle Wu, Qinchun Kang, Huishuang Wang, Jiajia Sun and Xiaofeng Wei

Cell Reports Physical Science, 2024, 5, 101831
DOI: 10.1016/j.xcrp.2024.101831

Recent Advances in the Functionalization of Terminal and Internal Alkynes

Arti Ramani, Bhargav Desai, Monak Patel and Togati Naveen

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202200047

Alkylcyanation of unactivated alkenes via photoinduced hydrogen atom transfer and 1,4-cyano migration

Meichen Xu, Pandaram Sakthivel, Zongyang Ma and Juntao Ye

Tetrahedron Letters, 2025, 159, 155516
DOI: 10.1016/j.tetlet.2025.155516

Dialkylation of Alkenes to Fluorinated δ-Lactams Enabled by Nickel-Electron-Shuttle Catalysis

Sunfeng Ye, Bangkui Yu and Hanmin Huang

Org. Lett., 2025, 27, 3225
DOI: 10.1021/acs.orglett.5c00515

Nickel‐Catalyzed Enantioselective Reductive Alkyl‐Carbamoylation of Internal Alkenes

Xianqing Wu, Aneta Turlik, Baixue Luan, Feng He, Jingping Qu, K. N. Houk and Yifeng Chen

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202207536

Photo‐Catalyzed Redox‐Neutral 1,2‐Dialkylation of Alkenes

Wen‐Hui Sun, Jian‐Yu Zou, Xiao‐Jing Xu, Jin‐Lin Wang, Mei‐Ling Liu and Xue‐Yuan Liu

Adv Synth Catal, 2022, 364, 2260
DOI: 10.1002/adsc.202200310

Nickel-catalyzed asymmetric 1,2-alkynylboration of vinylarenes

Mei Duan, You Wang and Shaolin Zhu

Tetrahedron Letters, 2023, 114, 154247
DOI: 10.1016/j.tetlet.2022.154247

Dual Transition Metal Electrocatalysis: Direct Decarboxylative Alkenylation of Aliphatic Carboxylic Acids

Jiaqing Lu, Yan Yao, Liubo Li and Niankai Fu

J. Am. Chem. Soc., 2023, 145, 26774
DOI: 10.1021/jacs.3c08839

Switchable Four- and Five-Component Reactions with Perfect Regioselectivity Promoted by Photoredox/Sulfide Dual-Catalytic Quenching for Access to Diverse Complex Imides

Kakeru Matsukuma, Masanori Tayu, Ryota Itai, Kotaro Imai, Sayaka Ohrui and Nozomi Saito

J. Org. Chem., 2025, 90, 10454
DOI: 10.1021/acs.joc.5c01232

Enantioselective domino alkyl arylation of vinyl phosphonates by combining photoredox and nickel catalysis

Tingzhi Lin, Guorong Li, Qianqian Lu, Chen Zhang, Yan-En Wang, Fei Xing, Yundong Xu, Kun Yang, Dan Xiong, Xiufang Xu, Patrick J. Walsh and Jianyou Mao

Green Synthesis and Catalysis, 2025, 6, 289
DOI: 10.1016/j.gresc.2024.04.001

Asymmetric cyanoesterification of vinylarenes by electrochemical copper catalysis

Kehan Zhou and Niankai Fu

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-62137-7

Cobalt-Catalyzed Alkene Alkylarylation: Access to Pyrrolidinones

Junda Wang, Kaixin Chen, Changrui Nie, Chenhao Huang, Qian Zhang and Jie Li

Org. Lett., 2025, 27, 9287
DOI: 10.1021/acs.orglett.5c02870

Dual Photoredox/Nickel Catalysis Enables Diastereoselective Synthesis of Multisubstituted γ-Lactams Using Alkyl-GeMe3 as Radical Precursors

Wen-Feng Li, Qing-Hao Xu, Qi-Yue Miao and Bin Xiao

J. Org. Chem., 2024, 89, 16269
DOI: 10.1021/acs.joc.3c02348

Pd/Cu-Cocatalyzed Enantio- and Diastereodivergent Wacker-Type Dicarbofunctionalization of Unactivated Alkenes

Wenzhi Zhu, Chongyu Han, Guoqiang Yang, Xiaohong Huo and Wanbin Zhang

J. Am. Chem. Soc., 2024, 146, 26121
DOI: 10.1021/jacs.4c06788

Nickel and photoredox dual-catalyzed regioselective dialkylation of alkenes

Fu Ye, Yiqian Yang, Wenlong Wang and Weiming Yuan

Chem Catalysis, 2023, 3, 100605
DOI: 10.1016/j.checat.2023.100605

Metallaphotoredox-Catalyzed Three-Component Asymmetric Cross-Electrophile Coupling for Chiral Boronate Synthesis

Xiaofang Li, Yuntong Hu, Zhonghou Huang, Shengqing Zhu, Feng-Ling Qing and Lingling Chu

ACS Catal., 2024, 14, 15790
DOI: 10.1021/acscatal.4c04316

Ni-Catalyzed Regioselective Alkylarylation of Unactivated Alkenes in Amines Enabled by Cooperative Ligand Effects of Nitriles and Electron-Deficient Alkenes

Vivek Aryal, Supuni I. N. Hewa Inaththappulige, Ayush Acharya and Ramesh Giri

J. Am. Chem. Soc., 2025, 147, 1667
DOI: 10.1021/jacs.4c12334

Revised Mechanism of C(sp3)–C(sp3) Reductive Elimination from Ni(II) with the Assistance of a Z-Type Metalloligand

Tao Zhang, Kangbao Zhong, Zhi-Keng Lin, Linbin Niu, Zi-Qi Li, Ruopeng Bai, Keary M. Engle and Yu Lan

J. Am. Chem. Soc., 2023, 145, 2207
DOI: 10.1021/jacs.2c09739

1,1-Regioselective alkenylboration of styrenes enabled by palladium catalysis

Dong Wu, Hailiang Pang and Guoyin Yin

Chinese Chemical Letters, 2023, 34, 108087
DOI: 10.1016/j.cclet.2022.108087

Directed Asymmetric Nickel‐Catalyzed Reductive 1,2‐Diarylation of Electronically Unactivated Alkenes

Zhan Dong, Qiongyao Tang, Changyu Xu, Li Chen, Haiting Ji, Sitian Zhou, Liangliang Song and Liang‐An Chen

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202218286

Formal β‐C−H Arylation of Aldehydes and Ketones by Cooperative Nickel and Photoredox Catalysis

Kun Liu and Armido Studer

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202206533

Visible-Light-Photocatalyzed Dicarbofunctionalization of Conjugated Alkenes with Ketone-Based Dihydroquinazolinones

Pinku Prasad Mondal, Subham Das, Sreelakshmi Venugopalan, Malavika Krishnan and Basudev Sahoo

Org. Lett., 2023, 25, 1441
DOI: 10.1021/acs.orglett.3c00175

Photoredox/nickel dual-catalysis-enabled synthesis of N-heterocycles from alkyl chlorides and alkenes

Xuege Yang, Lou Shi, Ruoyu Qin, Minglin Tao, Qin Feng, Xiao-Yong Chang, Qiaowen Chang and Deqiang Liang

Molecular Catalysis, 2024, 553, 113806
DOI: 10.1016/j.mcat.2023.113806

Nickel-Catalyzed Three-Component 1,1-Difunctionalization of Unactivated Alkenes with Quinoxaline/Naphthoquinone and Arylboronic Acids via Organometallic-Radical Relay

Lingyu Wan, Shankun Guo, Fanglu Sun, Ke Du, Lizhi Zhang and Zhengbao Xu

Org. Lett., 2024, 26, 11040
DOI: 10.1021/acs.orglett.4c04207

Copper-Catalyzed Three-Component Germyl Peroxidation of Alkenes

Yani Luo, Boxia Xu, Leiyang Lv and Zhiping Li

Org. Lett., 2022, 24, 2425
DOI: 10.1021/acs.orglett.2c00698

Nickel-Catalyzed Three-Component Alkylarylation of Alkenyl N-Heteroarenes

Teng Long, Ya-Li Zeng, Zhi-Hong Dong, Shu Li, Jie Zhan, Sheng-Min Zeng, Jia-Li Qiu, Wen-Dao Chu and Quan-Zhong Liu

Org. Lett., 2023, 25, 8344
DOI: 10.1021/acs.orglett.3c03474

Visible Light Induced Three‐Component 1,2‐Dicarbofunctionalization of Alkenes and Alkynes

Mrittika Mohar, Sumit Ghosh and Alakananda Hajra

The Chemical Record, 2023, 23
DOI: 10.1002/tcr.202300121

Dual nickel- and photoredox-catalyzed carbon-carbon bond formations via reductive cross-coupling involving organohalides

Hepan Wang and Tao XU

Chem Catalysis, 2024, 4, 100952
DOI: 10.1016/j.checat.2024.100952

Cross‐Electrophile C−PIII Coupling of Chlorophosphines with Organic Halides: Photoinduced PIII and Aminoalkyl Radical Generation Enabled by Pnictogen Bonding

Yong‐Liang Tu, Bei‐Bei Zhang, Bing‐Sheng Qiu, Zhi‐Xiang Wang and Xiang‐Yu Chen

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202310764

Iron-Catalyzed One-Pot Four-Component Synthesis of Dihydropyridinones from Benzyl Alcohols and Ketones

Humaira Parveen, Meshari A. Alsharif, Mohammed Issa Alahmdi, Omar M. Alatawi, Mona O. Albalawi, Sayeed Mukhtar and Mohd Waheed

Synthesis, 2026, 58, 204
DOI: 10.1055/a-2722-9900

Base‐Modulated 1,3‐Regio‐ and Stereoselective Carboboration of Cyclohexenes

Weiyu Kong, Yang Bao, Liguo Lu, Zhipeng Han, Yifan Zhong, Ran Zhang, Yuqiang Li and Guoyin Yin

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202308041

Modular access to alkylgermanes via reductive germylative alkylation of activated olefins under nickel catalysis

Rui Gu, Xiujuan Feng, Ming Bao and Xuan Zhang

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-43561-z

Divergent and Selective Light Alkene Cross‐Coupling

Zi‐Chao Wang, Jia‐Wen Zhang, Ming Joo Koh and Shi‐Liang Shi

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202310203

Atroposelective Three-Component (Fluoro)methylative Alkylation of Terminal Alkynes

Yaheng Zhao, Liping Huo, Xiaoyu Zhao and Lingling Chu

ACS Catal., 2025, 15, 63
DOI: 10.1021/acscatal.4c06100

Modulating stereoselectivity in allylic C(sp3)-H bond arylations via nickel and photoredox catalysis

Long Huang, Marcin Szewczyk, Rajesh Kancherla, Bholanath Maity, Chen Zhu, Luigi Cavallo and Magnus Rueping

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-36103-0

Nickel‐Catalyzed Cross‐Electrophile 1,2‐Silyl‐Arylation of 1,3‐Dienes with Chlorosilanes and Aryl Bromides

Qiu‐Quan Pan, Liangliang Qi, Xiaobo Pang and Xing‐Zhong Shu

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202215703

1,3-Difunctionalization of Alkenes by Cobaloxime Photocatalysis

Ji-Xin Yu, Yuan-Yuan Cheng, Xin-Yi Zeng, Bin Chen, Chen-Ho Tung and Li-Zhu Wu

Org. Lett., 2024, 26, 6809
DOI: 10.1021/acs.orglett.4c02027

Expedient Cyano‐hydroxylation of Alkenes Enabled by Halogen Atom Transfer Induced Radical Ring‐Opening Elaboration of 3‐Bromo‐isoxazoline Cycloadducts

Hui Wang, Qing Chen, Shuhui Wang, Cheng‐Qiang Wang and Chao Feng

Chin. J. Chem., 2025, 43, 2015
DOI: 10.1002/cjoc.70070

Copper-Catalyzed Three-Component Photo-ATRA-Type Reaction for Asymmetric Intermolecular C–O Coupling

Peng-Zi Wang, Yu-Jie Liang, Xue Wu, Wei Guan, Wen-Jing Xiao and Jia-Rong Chen

ACS Catal., 2022, 12, 10925
DOI: 10.1021/acscatal.2c03576

General Photo-Driven Chemoselective and Rapid Hydropentafluorosulfanylation of Alkenes via an Orchestrated Radical Chain Process

Yuan-Yang Jiang, Jiang-Shan Zhang, Donglei Sun, Gang Wu, Zhe-Chang Kuang, Ning Zhang, Xiang-Yu Shen, Xiao-Long Zhang, Jingwen Jiang, Hui-Yi Yang, Wei Zhang, Xiao-Song Xue and Shuo Guo

J. Am. Chem. Soc., 2025, 147, 43785
DOI: 10.1021/jacs.5c14406

Visible‐Light‐Induced Acyl and Thiocyano Pyridylation of Alkenes with Aldehyde and NH4SCN

Xu Wang, Qi‐Xuan Jiang, Bi‐Yin Xiao, Wei Huang and Feng‐Hua Zhang

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.202401373

Fe-Catalyzed Dicarbofunctionalization of Vinylarenes with Alkylsilyl Peroxides and β-Keto Carbonyl Substrates

Weiping Xu, Terumasa Kato, Yan Liu, Akira Matsumoto and Keiji Maruoka

Org. Lett., 2022, 24, 2641
DOI: 10.1021/acs.orglett.2c00656

Recent Advances in Photochemical Asymmetric Three‐Component Reactions

Haichao Huang, Yu‐Mei Lin and Lei Gong

The Chemical Record, 2023, 23
DOI: 10.1002/tcr.202300275

Cr-Catalyzed Diastereo- and Enantioselective Synthesis of β-Hydroxy Sulfides and Selenides

Xiaowen Xia and Zhaobin Wang

ACS Catal., 2022, 12, 11152
DOI: 10.1021/acscatal.2c03271

Nickel-Catalyzed Reductive Dicarbofunctionalization of Vinylarenes Enabled by Electrochemical Process

Pengwei Hu, Lin Guo, Lulu Zhao, Chao Yang and Wujiong Xia

Org. Lett., 2022, 24, 7583
DOI: 10.1021/acs.orglett.2c02976

Cross‐Electrophile C−PIII Coupling of Chlorophosphines with Organic Halides: Photoinduced PIII and Aminoalkyl Radical Generation Enabled by Pnictogen Bonding

Yong‐Liang Tu, Bei‐Bei Zhang, Bing‐Sheng Qiu, Zhi‐Xiang Wang and Xiang‐Yu Chen

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202310764

Photoredox/Nickel Dual-Catalyzed Allylation of Aldehydes with Allylic Alcohols and Mechanistic Insights in the Presence of CO2

Zeyu Zhang, Zongchang Han, Jiayuan Li, Han-Shi Hu, Jun Li and Chanjuan Xi

ACS Catal., 2024, 14, 12392
DOI: 10.1021/acscatal.4c03991

Cobalt-Catalyzed Asymmetric Reductive Dicarbofunctionalization of 1,3-Dienes with o-Bromoaryl Imines as a Bis-Electrophile

Decai Ding, Linchuan Zhang, Hao Wen and Chuan Wang

ACS Catal., 2023, 13, 744
DOI: 10.1021/acscatal.2c05438

Nickel‐Catalyzed Regio‐ and Stereoselective Reductive Alkylative Cyclization of 1,6‐Enynes with Alkyl Bromides

Yunxin Xing, Zhu Tian and Kun Shen

Adv Synth Catal, 2024, 366, 3802
DOI: 10.1002/adsc.202400575

Photoinduced Copper-Catalyzed Enantioselective Alkylalkynylation of Alkenes via Polarity-Matched Hydrogen Atom Transfer

Zhengze Wu, Kai Li, Mengxia Liao, Chunxiang Pan, Bin Yang, Xi Ma, Hengyu Huo, Binbin Tu, Guozhu Zhang and Rui Guo

J. Am. Chem. Soc., 2025, 147, 22072
DOI: 10.1021/jacs.5c06054

Ni-Catalyzed Remote Radical/Cross-Electrophile Coupling Cascade for Selective C(sp3)–H Arylation

Ya-Ting Wen, Xiang-Tao Kong, Hong-Chao Liu, Cui-Tian Wang, Wan-Xu Wei, Bin Wang, Xue-Yuan Liu and Yong-Min Liang

Org. Lett., 2022, 24, 2399
DOI: 10.1021/acs.orglett.2c00666

Palladium‐Catalyzed/Mn(OAc)3‐Mediated 1,2‐Diazidation and 1,2‐Acetoxy/Hydroxylation of N‐Allyl Sulfonamides

Marta Papis, Sara Colombo, Leonardo Lo Presti, Giovanni Poli, Gianluigi Broggini, Julie Oble and Camilla Loro

Adv Synth Catal, 2024, 366, 2477
DOI: 10.1002/adsc.202400035

Photocatalysis Meets Copper Catalysis: A New Opportunity for Asymmetric Multicomponent Radical Cross-Coupling Reactions

Peng-Zi Wang, Bin Zhang, Wen-Jing Xiao and Jia-Rong Chen

Acc. Chem. Res., 2024, 57, 3433
DOI: 10.1021/acs.accounts.4c00638

Alkylcyanation of Unactivated Alkenes with Protic C(sp3)−H Feedstocks via Radical‐Initiated Intramolecular Cyano Group Migration Enabled by Photoredox/Brønsted Base Dual Catalysis

Yang Hong and Hong‐Ping Deng

ChemPhotoChem, 2025, 9
DOI: 10.1002/cptc.202400282

Recent Progress in Radical Involved Alkene Dialkylation

Lingyi Lu and Xiaodong Qiu

Chinese Journal of Organic Chemistry, 2024, 44, 1701
DOI: 10.6023/cjoc202312020

Enantioselective three-component reaction to access chiral α-vinyl phosphonates

Kai Yang and Qiuling Song

Chem Catalysis, 2023, 3, 100539
DOI: 10.1016/j.checat.2023.100539

Photocatalyzed Dicyanation of Alkenes Enabled by Phosphorus Radical Cation Addition

Jing Li, Yanyan Zhang, Shengqing Zhu and Lingling Chu

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202501154

Multicomponent Construction of Tertiary Alkylamines by Photoredox/Nickel-Catalyzed Aminoalkylation of Organohalides

Tao Yang, Wenhui Xiong, Guangyu Sun, Weiran Yang, Mandi Lu and Ming Joo Koh

J. Am. Chem. Soc., 2024, 146, 29177
DOI: 10.1021/jacs.4c11602

Trichloromethyl‐Radical‐Initiated Three‐Component Reaction of Alkenes with CHCl3 and Quinoxalinones

Yechun Wu, Jie Zhang, Jin‐Tao Yu and Changduo Pan

Adv Synth Catal, 2023, 365, 687
DOI: 10.1002/adsc.202201307

Asymmetric paired oxidative and reductive catalysis enables enantioselective alkylarylation of olefins with C(sp3)−H bonds

Long Zou, Xinyue Zheng, XueZheng Yi and Qingquan Lu

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-52248-y

Electrophilic Sulfur Reagent Design Enables Directed syn-Carbosulfenylation of Unactivated Alkenes

Zi-Qi Li, Yilin Cao, Taeho Kang and Keary M. Engle

J. Am. Chem. Soc., 2022, 144, 7189
DOI: 10.1021/jacs.1c13252

Photoinduced Pd-Catalyzed Alkylvinylation of Alkenes via C–H Bond Elaboration

Wen-Ao Li, Xiao-Yun Ruan, Yi-Cong Liu, Hui Yu and Zhi-Yong Han

Org. Lett., 2025, 27, 12717
DOI: 10.1021/acs.orglett.5c03597

Directed Asymmetric Nickel‐Catalyzed Reductive 1,2‐Diarylation of Electronically Unactivated Alkenes

Zhan Dong, Qiongyao Tang, Changyu Xu, Li Chen, Haiting Ji, Sitian Zhou, Liangliang Song and Liang‐An Chen

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202218286

Recent Advances in Photoredox/Nickel Dual-Catalyzed Difunctionalization of Alkenes and Alkynes

Lei Xu, Fang Wang, Fan Chen, Shengqing Zhu and Lingling Chu

Chinese Journal of Organic Chemistry, 2022, 42, 1
DOI: 10.6023/cjoc202109002

O-Allylhydroxyamine: A Bifunctional Olefin for Construction of Axially and Centrally Chiral Amino Alcohols via Asymmetric Carboamidation

Ruijie Mi, Zhiying Ding, Songjie Yu, Robert H. Crabtree and Xingwei Li

J. Am. Chem. Soc., 2023, 145, 8150
DOI: 10.1021/jacs.3c01162

Copper‐Catalyzed Regiodivergent Asymmetric Difunctionalization of Terminal Alkynes

Simin Wang, Kexin Chen, Junbo Niu, Xiaobing Guo, Xiuping Yuan, Jianjun Yin, Bo Zhu, Dazhen Shi, Wei Guan, Tao Xiong and Qian Zhang

Angew Chem Int Ed, 2024
DOI: 10.1002/anie.202410833

Overcoming limitations in non-activated alkene cross-coupling with nickel catalysis and anionic ligands

Dong Wu, Weiyu Kong, Yang Bao, Chengmi Huang, Wei Liu, Yuqiang Li and Guoyin Yin

Nat Catal, 2024, 7, 1154
DOI: 10.1038/s41929-024-01211-7

Radical Alkylcyanation of 1,6-Enynes with Isonitriles as Bifunctional Reagents

Zhonghou Huang, Jian Qin, Yuntong Hu, Shengqing Zhu and Lingling Chu

Org. Lett., 2024, 26, 10763
DOI: 10.1021/acs.orglett.4c03744

Photo‐ and Electrochemical Asymmetric Cross‐Electrophile Couplings

Yumin Xu, Weisai Zu and Haohua Huo

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202500061

Catalytic Asymmetric Synthesis of Chiral Allenylic Fluorides Enabled by Multiple Radical Sorting

Yingying Li, Xian Gong, Ye Yuan, Yuyang Bai, Huan Li and Lingling Chu

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202518286

Copper-Catalyzed Hydroxyperfluoroalkylation of Unactivated Alkenes: Access to β-Perfluoroalkyl Alcohols

Luqing Tang, Cancan Feng, Fan Yang and Yangjie Wu

Org. Lett., 2023, 25, 2782
DOI: 10.1021/acs.orglett.3c00651

Three-Component Regioselective Aryl- and Alkenyl-Aminoalkylation of Alkenes via Cooperative Photoredox/Nickel Catalysis

Fu Ye and Weiming Yuan

J. Org. Chem., 2024, 89, 17708
DOI: 10.1021/acs.joc.4c02482

Recent advances in remote C(sp3)–H functionalization via chelating group-assisted metal-catalyzed chain-walking reaction

Jian Han, Li-Li Zeng, Qin-Yu Fei, Yan-Xiang Ge, Rong-Hui Huang and Fen-Er Chen

Chinese Chemical Letters, 2024, 35, 109647
DOI: 10.1016/j.cclet.2024.109647

Nickel-Catalyzed 1,2-Arylboration of Unactivated Alkenes to Access Boryl-Functionalized Aliphatic Amines

Xiao Meng, Lin Zhu, Jimin Liang, Haoran Shi, Jun Lv, Mengbo Wang, Lanlan Zhang and Chao Wang

Org. Lett., 2022, 24, 6962
DOI: 10.1021/acs.orglett.2c02768

Nickel-Catalyzed Reductive anti-Arylative Cyclization of 1,6-Enynes with Aryl Halides

Yunxin Xing, Denghong Yan, Shun Wen, Jie Bu and Kun Shen

Chinese Journal of Organic Chemistry, 2024, 44, 1938
DOI: 10.6023/cjoc202401001

Hemilabile and Redox‐Active Quinone Ligands Unlock sp3‐Rich Couplings in Nickel‐Catalyzed Olefin Carbosulfenylation

Zi‐Qi Li, Turki M. Alturaifi, Yilin Cao, Matthew V. Joannou, Peng Liu and Keary M. Engle

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202411870

Carbamoylarylation of Alkenes with N-Aryl Oxamic Acids Involving 1,4-Aryl Migration Via C(aryl)–N Bond Cleavage

Akira Shiozuka, Di Wu, Kyohei Kawashima, Toshifumi Mori, Kohei Sekine and Yoichiro Kuninobu

ACS Catal., 2024, 14, 5972
DOI: 10.1021/acscatal.4c00523

Directed Halogen Atom Transfer (DIXAT): A Powerful Tool for Chemoselective Generation of Aryl Radicals Toward Remote C(sp3)–H Functionalization of Aliphatic Amines

Sidhant Wagulde, Kevin P. Quirion, Turki M. Alturaifi, Peng Liu and Vladimir Gevorgyan

J. Am. Chem. Soc., 2025, 147, 29367
DOI: 10.1021/jacs.5c09218

Carbosulfonylation of Alkynes: A Direct Conversion of sp-C to sp3-C through Visible Light-Mediated 3-Component Reaction

Mandapati Bhargava Reddy, Vanessa E. Becker and Eoghan M. McGarrigle

Org. Lett., 2024, 26, 7858
DOI: 10.1021/acs.orglett.4c02700

Ruthenium‐katalysierte entfernte Difunktionalisierung nicht‐aktivierter Alkene für die doppelte meta‐C(sp2)−H/C‐6(sp3)−H‐Funktionalisierung

Shan Chen, Binbin Yuan, Yulei Wang and Lutz Ackermann

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202301168

Photoredox/Cr-catalyzed enantioselective radical-polar crossover transformation via C-H functionalization

Si-Yuan Tang, Zhan-Jie Wang, Yu Ao, Ning Wang and Huan-Ming Huang

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-56372-1

Modular and Practical 1,2‐Aryl(Alkenyl) Heteroatom Functionalization of Alkenes through Iron/Photoredox Dual Catalysis**

Weigang Zhang, Tao Liu, Hwee Ting Ang, Penghao Luo, Zhexuan Lei, Xiaohua Luo, Ming Joo Koh and Jie Wu

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202310978

Catalyst-controlled regiodivergent 1,2-difunctionalization of alkenes with two carbon-based electrophiles

Md. Belal, Zheqi Li, Lei Zhu and Guoyin Yin

Sci. China Chem., 2022, 65, 514
DOI: 10.1007/s11426-021-1172-x

Reversible Radical Addition Guides Selective Photocatalytic Intermolecular Thiol‐Yne‐Ene Molecular Assembly

Nikita S. Shlapakov, Andrey D. Kobelev, Julia V. Burykina, Alexander Yu. Kostyukovich, Burkhard König and Valentine P. Ananikov

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202314208

Cine‐Reductive Carboboration of Alkenyl Electrophiles via Iron Catalysis

Adong Qiao, Shasha Geng, Xianrong Chen, Jinping Yuan, Yun He, Mei Bai and Zhang Feng

Angew Chem Int Ed, 2026, 65
DOI: 10.1002/anie.202525623

Reverse Regioselective Dicarbofunctionalization via Anti‐Michael‐Type Addition

Hirotsugu Suzuki, Ryota Moro and Takanori Matsuda

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202505391

Nickel/Photo-Cocatalyzed Three-Component Alkyl-Acylation of Aryl-Activated Alkenes

Pei Fan, Zhe Chen and Chuan Wang

Org. Lett., 2023, 25, 8877
DOI: 10.1021/acs.orglett.3c03669

Photoredox/Nickel‐Cocatalyzed Asymmetric C–O and C–S Couplings for Atroposelective Synthesis of N‐Heterobiaryls

Tian‐Zhen Li, Cheng‐Cheng Tian, Wei Chen, Zi‐Yun Zou, Jia‐Liang Yang, Fang‐Xi Liu, Xinyao Li, Hong‐Hao Zhang and Feng Shi

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202516584

Radical Multicomponent Alkyl Alkynylation of Propellane via Synergistic Photoredox and Copper Catalysis

Jie Shi, Qiao-Lin Xu, Yu-Qing Ni, Lin Li and Fei Pan

Org. Lett., 2022, 24, 4609
DOI: 10.1021/acs.orglett.2c01721

Nickel-Catalyzed Three-Component Alkylacylation of Alkenes Enabled by a Photoactive Electron Donor–Acceptor Complex

Xiaoxiang Xi, Yukun Chen and Weiming Yuan

Org. Lett., 2022, 24, 3938
DOI: 10.1021/acs.orglett.2c01237

Highly selective α-C(sp3)-H arylation of alkenyl amides via nickel chain-walking catalysis

Haoran Shi, Jiaxin Wang, Yuqin Zhu, Hongyang Li, Guodong Ju, Lanlan Zhang and Chao Wang

Chinese Chemical Letters, 2024, 35, 109333
DOI: 10.1016/j.cclet.2023.109333

Dual NHC/Organophotoredox-Catalyzed Radical Phosphinoylacylation of Alkenes with Acyl Fluorides and H-Phosphine Oxides

Rongzao Yang, Jiabin Liao, Hui Xi, Miao-Miao Li and Wei Ding

J. Org. Chem., 2025, 90, 8767
DOI: 10.1021/acs.joc.5c00988

Stereoselective vicinal C(sp³)–C bond formation via metallaphotoredox 1,2-difunctionalization of internal alkenes

Yanyan Zhang, Tianyu Long, Yangxing Sun, Ye Yuan, Jing Li, Chuqian Tang, Feng-Ling Qing and Lingling Chu

Nat Commun, 2026, 17
DOI: 10.1038/s41467-026-69838-7

Three-component enantioselective alkenylation of organophosphonates via nickel metallaphotoredox catalysis

Xiaofang Li, Mingbin Yuan, Fan Chen, Zhonghou Huang, Feng-Ling Qing, Osvaldo Gutierrez and Lingling Chu

Chem, 2023, 9, 154
DOI: 10.1016/j.chempr.2022.09.020

Base‐Modulated 1,3‐Regio‐ and Stereoselective Carboboration of Cyclohexenes

Weiyu Kong, Yang Bao, Liguo Lu, Zhipeng Han, Yifan Zhong, Ran Zhang, Yuqiang Li and Guoyin Yin

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202308041

Palladium-Catalyzed Enantioselective Multicomponent Cross-Coupling of Trisubstituted Olefins

Wenyi Huang, Yang Xi, Deng Pan, Linlin Fan, Ke Fang, Genping Huang, Wei-Hong Zhu, Jingping Qu and Yifeng Chen

J. Am. Chem. Soc., 2024, 146, 16892
DOI: 10.1021/jacs.4c05480

Dual Nickel/Photoredox-Catalyzed Asymmetric Carbosulfonylation of Alkenes

Xiaoyong Du, Iván Cheng-Sánchez and Cristina Nevado

J. Am. Chem. Soc., 2023, 145, 12532
DOI: 10.1021/jacs.3c00744

Formal β‐C−H Arylation of Aldehydes and Ketones by Cooperative Nickel and Photoredox Catalysis

Kun Liu and Armido Studer

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202206533

Streamlined Alkylation via Nickel-Hydride-Catalyzed Hydrocarbonation of Alkenes

Zhikun Zhang, Srikrishna Bera, Chao Fan and Xile Hu

J. Am. Chem. Soc., 2022, 144, 7015
DOI: 10.1021/jacs.1c13482

Coordination-Assisted Ni-Catalyzed Regio- and Enantioselective 1,2-Borylalkylation of Unactivated Alkenes

Yuqin Zhu, Zhetai Feng, Wenyi Li, Jiaxin Wang, Guodong Ju and Chao Wang

Org. Lett., 2024, 26, 10622
DOI: 10.1021/acs.orglett.4c03791

Photocatalytic Germylation via Direct Hydrogen Atom Transfer

Wenshan Wang, Yan Liu, Gonghong Qiu, Igor B. Krylov, Alexander O. Terent’ev, Shuxia Cao, Kai Sun, Xiaolan Chen, Lingbo Qu and Bing Yu

Chin. J. Chem., 2025, 43, 1664
DOI: 10.1002/cjoc.70038

Recent advances in regioselective intermolecular three-component dialkylation of alkenes

Fu Ye, Peng Ren, Fan Luo, Xianzhou Zheng, Fangrui Zhong and Weiming Yuan

Sci. China Chem., 2026
DOI: 10.1007/s11426-025-3194-0

Ag(I)/Lewis Acid Cooperatively Promoted Three-Component Coupling for Carbo-Heterofunctionalization of Alkenes

Yigao Tao, Rong Hu, Xiaoming Jie and Weiping Su

ACS Catal., 2022, 12, 12670
DOI: 10.1021/acscatal.2c04099

Ketone Synthesis via Irradiation-Induced Generation of a Persistent Ketyl Radical from Acyl Azolium Salts

Shihao Li, Chenglong Zheng, Sheng Wang, Xiao-Xuan Li, Qi Zhang, Shilu Fan and Yi-Si Feng

Org. Lett., 2023, 25, 6522
DOI: 10.1021/acs.orglett.3c02300

Visible‐Light Mediated Nickel‐Catalyzed Asymmetric Difunctionalizations of Alkenes

Han‐Tong Zhao, Jia‐Ni Lin and Wei Shu

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202402712

Catalytic Asymmetric Synthesis of Chiral Allenylic Fluorides Enabled by Multiple Radical Sorting

Yingying Li, Xian Gong, Ye Yuan, Yuyang Bai, Huan Li and Lingling Chu

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202518286

Regioreversed Carbosulfenylation of Fluoroalkenes via Nickel‐Mediated Radical Sorting

Chuan Zhu, Qian Liu, Nannan Wang, Rui Ma, Kai Chen, Patrick J. Walsh, Kai Guo and Chao Feng

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202509664

Ni-Catalyzed Reductive Dibenzylation of Trifluoromethylalkenes for CF3-Containing All-Carbon Quaternary Center Construction

Kai Chen, Qian Liu, Jinyan Wan, Chuan Zhu and Chao Feng

Org. Lett., 2023, 25, 5995
DOI: 10.1021/acs.orglett.3c02102

Cu-Catalyzed Asymmetric Three-Component Radical Acylarylation of Vinylarenes with Aldehydes and Aryl Boronic Acids

Zhiheng Li, Shang Wang, Si-Cong Chen, Xiangwen Zhu, Zhengzhen Lian and Dong Xing

J. Am. Chem. Soc., 2024, 146, 32235
DOI: 10.1021/jacs.4c08957

Access to Axially Chiral Vinyl Sulfilimines via Copper‐Catalyzed Enantioselective Radical Relay Trifluoromethyl‐Sulfilimination of Terminal Alkynes

Wei Wang, Qi Yang, Yunfei Yao, Lan Hu, Mingwei Jiang, Juan Tan, Guangfan Zheng, Jichao Xiao and Xingwei Li

Angewandte Chemie, 2026, 138
DOI: 10.1002/ange.202523530

Visible-Light-Promoted Intermolecular β-Acyl Difunctionalization of Alkenes via Oxidative Radical-Polar Crossover

Hao-Cong Li, Ke-Yuan Zhao, Yan Tan, Hao-Sen Wang, Wen-Shan Wang, Xiao-Lan Chen and Bing Yu

Org. Lett., 2023, 25, 8067
DOI: 10.1021/acs.orglett.3c03121

Dicarbofunctionalization of Vinylarenes with Pyridine and Aldehydes via Photocatalytic Hydrogen Atom Transfer

Junhua Xu, Yiting Zhou and Bin Liu

J. Org. Chem., 2024, 89, 15877
DOI: 10.1021/acs.joc.4c02016

Photochemistry‐Enabled Nitrogen‐Assisted Organostibines as an Efficient Alkyl Radical Precursor: Mechanistic Insights and Synthetic Applications

Niu Tang, Xinyu Li, Chenghan Li, Liyuan Le, Yifeng Ou, Shuangfeng Yin and Renhua Qiu

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202514967

Copper-catalyzed synthesis of γ-amino acids with indole units via radical dicarbofunctionalization of 2-azadienes

Shengzu Duan, Ya Du, Lening Zhang, Shuntao Huang, Sina Liu, Xiang Yang, Hongbin Zhang, Patrick J. Walsh and Xiaodong Yang

Sci. China Chem., 2026
DOI: 10.1007/s11426-025-3157-x

Nickel/photoredox dual catalyzed arylalkylation of nonactivated alkenes

Yuxi Gao, Lijuan Gao, Endiao Zhu, Yunhong Yang, Mi Jie, Jiaqian Zhang, Zhiqiang Pan and Chengfeng Xia

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-43748-4

Selective Three-Component Reductive Alkylalkenylation of Unbiased Alkenes via Carbonyl-Directed Nickel Catalysis

Fang Wang, Shiwei Pan, Shengqing Zhu and Lingling Chu

ACS Catal., 2022, 12, 9779
DOI: 10.1021/acscatal.2c02163

Visible-light-driven three-component reductive 1,2-diarylation of alkenes

Tao Wang, Weijie Yu, Jinping Lan, Hongyu Wang, Zhou Jiang, Yang Li and Junkai Fu

Chem Catalysis, 2023, 3, 100619
DOI: 10.1016/j.checat.2023.100619

Regioselective Alkylpolyfluoroarylation of Styrenes by Copper-Catalyzed C(sp3)–H and C(sp2)–H Double Activation

Chenggong Zheng, Fangpei Yan, Yaomei Liu, Rui Chen, Kaiting Zheng, Hua Xiao, Xiao-Xuan Li, Yi-Si Feng and Shilu Fan

Org. Lett., 2022, 24, 5462
DOI: 10.1021/acs.orglett.2c02197

Recent Progress on the Difunctionalization Reaction of 1,3-Enynes

Lianglong Sun and Kai Sun

Chinese Journal of Organic Chemistry, 2025, 45, 3655
DOI: 10.6023/cjoc202502004

Double alkyl–alkyl bond construction across alkenes enabled by nickel electron-shuttle catalysis

Changqing Rao, Tianze Zhang, Hongchi Liu and Hanmin Huang

Nat Catal, 2023, 6, 847
DOI: 10.1038/s41929-023-01015-1

Copper-Catalyzed Difluoroalkylative Benzylation of Alkenes

Shulei Ge, Xiaonuo Shi and Jie Li

Org. Lett., 2025, 27, 7445
DOI: 10.1021/acs.orglett.5c02355

Selective Ni-catalyzed cross-electrophile coupling of alkynes, fluoroalkyl halides, and vinyl halides

Yubei Dai, Fang Wang, Shengqing Zhu and Lingling Chu

Chinese Chemical Letters, 2022, 33, 4074
DOI: 10.1016/j.cclet.2021.12.050

Three‐Component Reaction of Pentafluorosulfanyl Chloride, Alkenes and Diazo Compounds and Synthesis of Pentafluorosulfanylfurans

Jia‐Yi Shou and Feng‐Ling Qing

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202208860

Ligand-Modulated Nickel/Photoredox-Catalyzed exo-Arylalkylation of Alkynes

Lijuan Gao, Jiaqian Zhang, Na Zhang, Mi Jie, Zhiqiang Pan and Chengfeng Xia

Org. Lett., 2025, 27, 3170
DOI: 10.1021/acs.orglett.5c00449

Base-Promoted One-Pot Four-Component Domino Strategy Involving Aldehydes and Ketones to Access Multifunctionalized Dihydropyridinones

Hao Lu, Xinyu Li, Zhiqing Wang, Peng Du, Shuang-Feng Yin, Nobuaki Kambe and Renhua Qiu

J. Org. Chem., 2024, 89, 15574
DOI: 10.1021/acs.joc.4c01636

Controllable Radical Reactions of 1,3-Dienes with Light

Shiwei Lü and Jin Xie

ACS Catal., 2025, 15, 7749
DOI: 10.1021/acscatal.5c01867

Induced-Fit Chiral N-Heterocyclic Carbene Ligands for Asymmetric Catalysis

Zi-Chao Wang and Shi-Liang Shi

Acc. Chem. Res., 2025, 58, 2157
DOI: 10.1021/acs.accounts.5c00304

Copper‐Catalyzed Enantioselective C(sp3)−SCF3 Coupling of Carbon‐Centered Benzyl Radicals with (Me4N)SCF3

Wei Zhang, Yu Tian, Xiao‐Dong Liu, Cheng Luan, Ji‐Ren Liu, Qiang‐Shuai Gu, Zhong‐Liang Li and Xin‐Yuan Liu

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202319850

Oxoammonium Salt-Mediated Regioselective Vicinal Dioxidation of Alkenes: Relying on Transient and Persistent Nitroxides

Yang Zheng, Qing-Yun Yang, Lu-Yan Wu, Xin-Yue Zhu, Ming-Jing Ge, Hao Yang, Shi-Yu Liu and Fei Chen

Org. Lett., 2021, 23, 8533
DOI: 10.1021/acs.orglett.1c03196

Oxidative lactonization of C(sp3)-H bond in methyl aromatic alcohols enabled by proton-coupled electron transfer

Shanyi Chen, Qihong Lai, Chao Liu, Hui Liu, Mingqiang Huang and Shunyou Cai

Sci. China Chem., 2022, 65, 1526
DOI: 10.1007/s11426-022-1283-7

Methylalkylation of Unactivated Alkenes by Photoredox/Nickel Catalytic HAT and Radical Selectivity Control

Hui Zhang, Ying-Jie Wang, Hao-Wen Jiang and Peng-Fei Xu

Org. Lett., 2026, 28, 2254
DOI: 10.1021/acs.orglett.5c05168

B-Alkyl-borabicyclo[3.3.1]nonane Reagents Promote Closed-Shell Nickel-Catalyzed Alkylarylation Toward Encoded Cyclooctene Monomers

Anne K. Ravn, Aimee L. Bangerter, Ethan M. Wagner, Shijia Li, Camille Z. Rubel, Steven R. Wisniewski, Peng Liu, Will. R. Gutekunst and Keary M. Engle

ACS Cent. Sci., 2026, 12, 324
DOI: 10.1021/acscentsci.5c02173

Late‐Stage Modification of Oligopeptides by Nickel‐Catalyzed Stereoselective Radical Addition to Dehydroalanine

Xiaoxu Qi, Subramanian Jambu, Yining Ji, Kevin M. Belyk, Nihar R. Panigrahi, Paramjit S. Arora, Neil A. Strotman and Tianning Diao

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202213315

Nickel‐Catalyzed Regiodivergent Acylzincation of Styrenes with Organozincs and CO†

Chenglong Wang, Ning Liu, Xianqing Wu, Jingping Qu and Yifeng Chen

Chin. J. Chem., 2024, 42, 599
DOI: 10.1002/cjoc.202300590

Intermolecular Photocatalytic Chemo‐, Stereo‐ and Regioselective Thiol–Yne–Ene Coupling Reaction

Julia V. Burykina, Andrey D. Kobelev, Nikita S. Shlapakov, Alexander Yu. Kostyukovich, Artem N. Fakhrutdinov, Burkhard König and Valentine P. Ananikov

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202116888

Iron-Catalyzed Alkylative Aminosulfonylation of Alkenes and Alkynes via Radical-Anion Relay

Xiaoya Hou, Bangkui Yu and Hanmin Huang

Org. Lett., 2025, 27, 5343
DOI: 10.1021/acs.orglett.5c01171

Three-Component Alkyl-Diborylmethylation of Alkenes Enabled by Dual Photoredox/Copper Catalysis

Qinqi He, Jiahao Zhang, Die Deng, Ying Fan, Qiang Wang, Ye Hua, Su Jing and Jiefeng Hu

Org. Lett., 2026, 28, 746
DOI: 10.1021/acs.orglett.5c04923

Nickel-Catalyzed 8-Aminoquinoline Directed Reductive Dialkylcyclization/Homodialkylation of Unactivated Alkenes

Lingyi Lu, Jing Sui, Shanshan Huang, Biao Xiong, Xiaobao Zeng, Xiaodong Qiu and Yanan Zhang

Org. Lett., 2023, 25, 7800
DOI: 10.1021/acs.orglett.3c02955

Reversible Radical Addition Guides Selective Photocatalytic Intermolecular Thiol‐Yne‐Ene Molecular Assembly

Nikita S. Shlapakov, Andrey D. Kobelev, Julia V. Burykina, Alexander Yu. Kostyukovich, Burkhard König and Valentine P. Ananikov

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202314208

Nickel-Mediated Radical Capture: Evidence for a Concerted Inner-Sphere Mechanism

Ethan H. Spielvogel, Jonathan Yuan, Norah M. Hoffmann and Tianning Diao

J. Am. Chem. Soc., 2025, 147, 19632
DOI: 10.1021/jacs.5c01554

Reverse Regioselective Dicarbofunctionalization via Anti‐Michael‐Type Addition

Hirotsugu Suzuki, Ryota Moro and Takanori Matsuda

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202505391

Nickel/Photoredox-Catalyzed Three-Component Dialkylation of Alkenes for the Synthesis of β-Amino Acid Derivatives

Fu Ye, Peiwen Liu, Yiqian Yang, Wei Gao and Weiming Yuan

Synlett, 2025, 36, 1917
DOI: 10.1055/a-2577-4281

Copper-Catalyzed Highly Efficient and Asymmetric Allylic C–H Oxidation of 3-Aryl-Substituted Terminal Alkenes

Yibo Zhou, Pinhong Chen and Guosheng Liu

J. Am. Chem. Soc., 2025, 147, 22873
DOI: 10.1021/jacs.5c05382

Asymmetric Alkylative Difunctionalization of Carbon–Carbon Double Bonds by Aliphatic C─H Bond Activation

Zilong Yan, Shang Wang, Xinyu Mao and Dong Xing

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202401380

Noncovalent interaction–driven regio- and enantioselective hydroalkynylation of unactivated alkenes to access remote chiral nitriles

Fanling Meng, Xian He, Rui He, Guodong Ju, Genping Huang and Chao Wang

Sci. Adv., 2025, 11
DOI: 10.1126/sciadv.ady4028

Ligand-Controlled Regioreversed 1,2-Aryl-Aminoalkylation of Alkenes Enabled by Photoredox/Nickel Catalysis

Fu Ye, Songlin Zheng, Yixin Luo, Xiaotian Qi and Weiming Yuan

ACS Catal., 2024, 14, 8505
DOI: 10.1021/acscatal.4c01312

Copper-Catalyzed Enantioselective Three-Component Fluoroalkylalkynylation of Unactivated Alkenes

Mengxia Liao, Cuihuan Geng, Zhengze Wu, Chunxiang Pan, Chenwei Wang, Guanghui Meng, Xiaoyan Zuo, Ying Zhu, Xiaotian Qi, Guozhu Zhang and Rui Guo

ACS Catal., 2025, 15, 1693
DOI: 10.1021/acscatal.4c06641

Enantioselective Synthesis of Chiral γ‐Amino Acid Esters via Photoredox/Nickel‐Catalyzed Aryl‐Aminoalkylation of Alkenes

Fu Ye, Youzhi Xu, Songlin Zheng, Genping Huang and Weiming Yuan

Chin. J. Chem., 2025, 43, 1862
DOI: 10.1002/cjoc.70060

Iron-catalyzed fluoroalkylative alkylsulfonylation of alkenes via radical-anion relay

Xiaoya Hou, Hongchi Liu and Hanmin Huang

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-45867-y

Nickel/Photoredox-Catalyzed Asymmetric Three-Component Cross-Coupling To Access Enantioenriched 1,1-Diaryl(heteroaryl)alkanes

Xueying Gao, Tingzhi Lin, Yan-En Wang, Fei Xing, Yanfeng Qiu, Dan Xiong and Jianyou Mao

Org. Lett., 2024, 26, 8792
DOI: 10.1021/acs.orglett.4c03151

Recent Advances in Nickel Catalyzed Asymmetric Acylation Reactions

Yanyan Zhang, Zhuzhu Zhang, Shengqing Zhu and Lingling Chu

Chinese Journal of Organic Chemistry, 2023, 43, 1023
DOI: 10.6023/cjoc202211032

Metal‐Free and Visible Light‐Induced Difunctionalizations of α‐CF3 Styrenes with Aryl Diazonium Salts and Hetero Nucleophiles

Lu Zhang, Shuai Liu, Mingming Ma, Yuncheng Shen, Pin Gao, Li‐Na Guo and Xin‐Hua Duan

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202300846

Photoinduced Nickel-Catalyzed Homolytic C(sp3)–N Bond Activation of Isonitriles for Selective Carbo- and Hydro-Cyanation of Alkynes

Jian Qin, Yingying Li, Yuntong Hu, Zhonghou Huang, Weihang Miao and Lingling Chu

J. Am. Chem. Soc., 2024, 146, 27583
DOI: 10.1021/jacs.4c08631

Ni‐Catalyzed Linearizable Cyclization/Coupling with Detachable Silicon‐Oxygen Linker: Access to 1,2‐Oxasilolanes, 3‐Hydroxysilanes and 4‐Arylalkanols

Margaret G. Lakomy, Majji Shankar, Ava C. Del Rio and Ramesh Giri

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202404679

Regioreversed Carbosulfenylation of Fluoroalkenes via Nickel‐Mediated Radical Sorting

Chuan Zhu, Qian Liu, Nannan Wang, Rui Ma, Kai Chen, Patrick J. Walsh, Kai Guo and Chao Feng

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202509664

Ruthenium‐Catalyzed Remote Difunctionalization of Nonactivated Alkenes for Double meta‐C(sp2)−H/C‐6(sp3)−H Functionalization

Shan Chen, Binbin Yuan, Yulei Wang and Lutz Ackermann

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202301168

Modular Assembly of E-Selective Trisubstituted Alkenylborons via Nickel-Catalyzed Reductive Dicarbofunctionalization of Ethynylboron

Yifan Ping and Jianbo Wang

ACS Catal., 2024, 14, 18204
DOI: 10.1021/acscatal.4c05549

Three-Component Visible-Light-Induced Palladium-Catalyzed 1,2-Alkyl Carbamoylation/Cyanation of Alkenes

Xiangqing Jia, Ziyan Zhang and Vladimir Gevorgyan

ACS Catal., 2021, 11, 13217
DOI: 10.1021/acscatal.1c04183

Ni-Catalyzed Enantioselective Intramolecular Mizoroki–Heck Reaction for the Synthesis of Phenanthridinone Derivatives

Diana Rachii, Dana J. Caldwell, Yui Kosukegawa, Mary Sexton, Paul R. Rablen and William P. Malachowski

J. Org. Chem., 2023, 88, 8203
DOI: 10.1021/acs.joc.3c00202

A Highly Regioselective Three‐Component Radical Coupling of Alkenes with Carboxylic Acids and Their Derivatives

Bo Ling, Haonan Bai, Siwei Hu, Zhehan Liang, Hongliang Chen, Xianli Yang, Weipeng Li, Chengjian Zhu and Jin Xie

Chin. J. Chem., 2026
DOI: 10.1002/cjoc.70498

Photoredox/Ni-Catalytic Synthesis of cis-Vinyl Iodides from Acetylene

Kangkui Li, Yue Huang, Xianyang Long, Dong Zhu, Yang Chen and Shifa Zhu

J. Am. Chem. Soc., 2025, 147, 37157
DOI: 10.1021/jacs.5c08849

Recent Advances in Theoretical Studies on Cu-Mediated Bond Formation Mechanisms Involving Radicals

Ji-Ren Liu, Guo-Xiong Xu, Li-Gao Liu, Shuo-Qing Zhang and Xin Hong

ACS Catal., 2024, 14, 2429
DOI: 10.1021/acscatal.3c06042

Transition metal-catalyzed asymmetric three-component dicarbofunctionalization of unactivated alkenes

Jian Han, Rui He and Chao Wang

Chem Catalysis, 2023, 3, 100690
DOI: 10.1016/j.checat.2023.100690

Ligand-enabled Ni-catalysed dicarbofunctionalisation of alkenes with diverse native functional groups

Dao-Ming Wang, Hui-Mei Shan, Li-Qin She, Yu-Qing He, Yichen Wu, Yong Tang, Li-Ping Xu and Peng Wang

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-54170-9

Palladium-catalyzed asymmetric migratory diarylation of unactivated directing-group-free internal alkenes

Linlin Fan, Yang Xi, Honglei Gu, Wenyi Huang, Wei-Hong Zhu, Jingping Qu and Yifeng Chen

Nat Commun, 2026, 17
DOI: 10.1038/s41467-025-68006-7

Enantio- and Regioselective Ni-Catalyzed Radical Relay 1,4-Arylalkylation of 1,3-Enynes to Access Chiral Tetrasubstituted Allenes

Jinze Du, Anyao Liu, Wen Zhang, Shan Luo, Hequan Yao and Yuli He

ACS Catal., 2024, 14, 13940
DOI: 10.1021/acscatal.4c04371

Harnessing Bromo/Acyloxy Transposition (BrAcT) and Excited-State Copper Catalysis for Styrene Difunctionalization

Upasana Mukherjee, Jagrut A. Shah, Djamaladdin G. Musaev and Ming-Yu Ngai

J. Am. Chem. Soc., 2024, 146, 21271
DOI: 10.1021/jacs.4c08984

Visible-light-induced photocatalyst- and metal-free radical phosphinoyloximation of alkenes with tert-butyl nitrite as bifunctional reagent

Huaixiang Yang, Miao-Miao Li, Aijun Zhang, Jiefei Guo, Yongqi Yu and Wei Ding

Chinese Chemical Letters, 2025, 36, 110425
DOI: 10.1016/j.cclet.2024.110425

Cu(I)-catalysed chemo-, regio-, and stereoselective radical 1,2-carboalkynylation with two different terminal alkynes

Jun-Qian Bian, Li Qin, Li-Wen Fan, Jiajia Fu, Yong-Feng Cheng, Yu-Feng Zhang, Qiao Song, Peng-Fei Wang, Zhong-Liang Li, Qiang-Shuai Gu, Peng Yu, Jun-Bin Tang and Xin-Yuan Liu

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-60012-z

Rapid Synthesis of β-Chiral Sulfones by Ni-Organophotocatalyzed Enantioselective Sulfonylalkenylation of Alkenes

Ming-Shang Liu and Wei Shu

JACS Au, 2023, 3, 1321
DOI: 10.1021/jacsau.3c00069

Nickel/Photoredox Dual-Catalyzed, Regioselective 1,2-Carboacylation of Alkenes via Synergistic Alkyl and Benzoyl Radical Coupling

Xian-Chen He, Jie Gao, Li Yang, Kai Chen and Hua Yang

Org. Lett., 2025, 27, 4933
DOI: 10.1021/acs.orglett.5c01230

Nickel-Catalyzed Radical Mechanisms: Informing Cross-Coupling for Synthesizing Non-Canonical Biomolecules

Gregory A. Dawson, Ethan H. Spielvogel and Tianning Diao

Acc. Chem. Res., 2023, 56, 3640
DOI: 10.1021/acs.accounts.3c00588

Synthesis of Hexafluoroisopropyl Aryl Ethers via Dual Photoredox/Nickel-Catalyzed C–O Coupling

Xu He, Yu-Yang Zhang, Jia-Yi Shou, Lingling Chu and Feng-Ling Qing

Org. Lett., 2024, 26, 6782
DOI: 10.1021/acs.orglett.4c02553

Intermolecular Photocatalytic Chemo‐, Stereo‐ and Regioselective Thiol–Yne–Ene Coupling Reaction

Julia V. Burykina, Andrey D. Kobelev, Nikita S. Shlapakov, Alexander Yu. Kostyukovich, Artem N. Fakhrutdinov, Burkhard König and Valentine P. Ananikov

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202116888

Advances in Nickel-Metallaphotoredox Catalysis in Organic Synthesis: A New Approach to Targeted Reaction Design

Susmita Podder

COC, 2026, 30, 303
DOI: 10.2174/0113852728378634250618190946

Ruthenium-Catalyzed Remote Trifunctionalization of Non-Activated Alkenes via Cyano Migration and meta-C(sp2)–H Functionalization

Jun-Lei Zhang, Xin-Lan Zhao, You-Zhi Liao, Yi Zhao and Fei Pan

Org. Lett., 2025, 27, 1106
DOI: 10.1021/acs.orglett.4c04445

Modular and Practical 1,2‐Aryl(Alkenyl) Heteroatom Functionalization of Alkenes through Iron/Photoredox Dual Catalysis**

Weigang Zhang, Tao Liu, Hwee Ting Ang, Penghao Luo, Zhexuan Lei, Xiaohua Luo, Ming Joo Koh and Jie Wu

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202310978

α‐Acylation of Alkenes by a Single Photocatalyst

Yuan‐Yuan Cheng, Hong‐Yu Hou, Yu Liu, Ji‐Xin Yu, Bin Chen, Chen‐Ho Tung and Li‐Zhu Wu

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202208831

Photoinduced Single‐Electron Reduction of Alkenes.

Xiang Li, Yong‐Liang Tu and Xiang‐Yu Chen

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202301060

Catalytic reductive annulation reactions of alkenes using dihaloalkanes

Sayan Roy, Divya Garg and Christopher Uyeda

Tetrahedron Letters, 2025, 168, 155705
DOI: 10.1016/j.tetlet.2025.155705

Cascade Hydrothiolation and Hydroamidation of Alkynes to Regioselectively Afford 1,2‐Disubstituted Alkane Derivatives under Photocatalysis

Rui Fu, Mengyu Xu, Yujing Wang and Xiaoguang Bao

Chin. J. Chem., 2026, 44, 462
DOI: 10.1002/cjoc.70380

Three-Component Carbosulfonylation of Alkenes via Single-Atom Nickel Photocatalysis

Han Wang, Mengting Wu, Qian Yang, Wentao Wang, Yurong Tang and Yunfei Cai

Org. Lett., 2026, 28, 4331
DOI: 10.1021/acs.orglett.6c00998

Triple cross-electrophile coupling enabled by palladium/norbornene cooperative catalysis

Jinxiang Ye, Lifang Qi, Shuang Deng, Dandan Wang, Hengjiang Cong, Xiaotian Qi, Qianghui Zhou and Hong-Gang Cheng

Sci. Adv., 2025, 11
DOI: 10.1126/sciadv.adu4573

Photocatalytic Late-Stage C–H Functionalization

Peter Bellotti, Huan-Ming Huang, Teresa Faber and Frank Glorius

Chem. Rev., 2023, 123, 4237
DOI: 10.1021/acs.chemrev.2c00478

Radical Carbonyl Umpolung Arylation via Dual Nickel Catalysis

Huan-Ming Huang, Peter Bellotti, Johannes E. Erchinger, Tiffany O. Paulisch and Frank Glorius

J. Am. Chem. Soc., 2022, 144, 1899
DOI: 10.1021/jacs.1c12199

Enantioselective Directed Nickel-Catalyzed Three-Component Reductive Arylalkylation of Alkenes via the Carbometalation/Radical Cross-Coupling Sequence

Zhan Dong, Changyu Xu, Jianchao Chang, Sitian Zhou, Peipei Sun, Yuqiang Li and Liang-An Chen

ACS Catal., 2024, 14, 4395
DOI: 10.1021/acscatal.4c00477

Ligand-controlled stereodivergent alkenylation of alkynes to access functionalized trans- and cis-1,3-dienes

Tianyu Long, Chen Zhu, Ling Li, Liang Shao, Shengqing Zhu, Magnus Rueping and Lingling Chu

Nat Commun, 2023, 14
DOI: 10.1038/s41467-022-35688-2

Nickel‐Catalyzed Regioselective Intermolecular Dialkylation of Alkenylarenes: Generation of Two Vicinal C(sp3)−C(sp3) Bonds Across Alkenes**

Daniel M. Lux, Vivek Aryal, Doleshwar Niroula and Ramesh Giri

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202305522

Divergent Carbocyanation and Hydrocyanation of Alkynes Enabled by Photoinduced Nickel-Catalyzed Homolytic Bond Cleavage of C(sp3)–N Bond in Isonitriles

Zhuzhu Zhang, Jian Qin, Shengqing Zhu and Lingling Chu

Synlett, 2025, 36, 1461
DOI: 10.1055/a-2572-0925

Nickel‐Catalyzed Enantioselective Reductive Alkyl‐Carbamoylation of Internal Alkenes

Xianqing Wu, Aneta Turlik, Baixue Luan, Feng He, Jingping Qu, K. N. Houk and Yifeng Chen

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202207536

Three‐Component Reaction of Pentafluorosulfanyl Chloride, Alkenes and Diazo Compounds and Synthesis of Pentafluorosulfanylfurans

Jia‐Yi Shou and Feng‐Ling Qing

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202208860

Hemilabile and Redox‐Active Quinone Ligands Unlock sp3‐Rich Couplings in Nickel‐Catalyzed Olefin Carbosulfenylation

Zi‐Qi Li, Turki M. Alturaifi, Yilin Cao, Matthew V. Joannou, Peng Liu and Keary M. Engle

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202411870

The review of sodium and potassium-ion battery advances in density functional theory: Progresses, challenges and prospects

Mei Yang, Shuling Chen, Yunqi Jia and Liuzhang Ouyang

Materials Science and Engineering: R: Reports, 2026, 167, 101097
DOI: 10.1016/j.mser.2025.101097

Catalytic Arylalkylation of Alkenyl Amines at Remote Sites via Directed Nickel Catalysis

Jian Han, Yinheng Tang, Jie Huang, Chun Luo, Lanlan Zhang, Wenyi Li and Chao Wang

Chin. J. Chem., 2023, 41, 631
DOI: 10.1002/cjoc.202200647

Reductive Radical-Polar Crossover Enabled Carboxylative Alkylation of Aryl Thianthrenium Salts with CO2 and Styrenes

Weiguan Qi, Shiyu Gu and Lan-Gui Xie

Org. Lett., 2024, 26, 728
DOI: 10.1021/acs.orglett.3c04183

Evaluation of Elementary Steps in Csp2–Csp3 Cross-Electrophile Coupling Reactions Mediated by a Common Ni Complex

Hunter F. Starbuck, Long P. Dinh, Dipannita Kalyani and Christo S. Sevov

J. Am. Chem. Soc., 2025, 147, 48107
DOI: 10.1021/jacs.5c15344

Mechanistic Insights into the Light-Driven Difunctionalization of Alkenes with a Sulfonyl-Based Reagent: A Catalyst-Free Approach

Rakesh Maiti, Aritra Nath, Ana B. R. Guimarães, Sergey Bagnich, Anna Köhler, Feliu Maseras and Shoubhik Das

J. Am. Chem. Soc., 2025, 147, 38021
DOI: 10.1021/jacs.5c08562

Recent Progress on Nickel‐Catalyzed Reductive Dicarbofunctionalization of Alkenes†

Yucheng Liu, Fu‐Yu Li, Muneer‐ul‐Shafi Bhat, Lan Tian, Hao‐Ran Zhang, Huan Meng, Han‐Tong Zhao, Yu‐Long Li and Wei Shu

Chin. J. Chem., 2025, 43, 3637
DOI: 10.1002/cjoc.70231

Photoredox 1,2-Alkylarylation of Alkenes with 1-(Allyloxy)-2-iodobenzenes and Cyano(hetero)aromatics Involving XAT-Enabled Annulation

Qing-Lin Liang, Liang Zeng, Ming Hu, Peiyuan Wang and Jin-Heng Li

J. Org. Chem., 2026, 91, 4259
DOI: 10.1021/acs.joc.5c03117

Direct Accessing γ-Pyridyl Tertiary Alcohols through Metal-Free Three-Component Reactions

Yiduo Zhang and Bin Liu

Synlett, 2025, 36, 1064
DOI: 10.1055/a-2500-7964

Nickel‐Catalyzed Asymmetric Reductive 1,4‐ and 1,5‐Dicarbofunctionalization†

Yutong Xiang, Chang Zhang and Chuan Wang

Chin. J. Chem., 2025, 43, 1271
DOI: 10.1002/cjoc.202500074

Synthesis of Axially Chiral Vinyl Halides via Cu(I)-Catalyzed Enantioselective Radical 1,2-Halofunctionalization of Terminal Alkynes

Jun-Bin Tang, Jun-Qian Bian, Zhihan Zhang, Yong-Feng Cheng, Li Qin, Qiang-Shuai Gu, Peiyuan Yu, Zhong-Liang Li and Xin-Yuan Liu

ACS Catal., 2025, 15, 502
DOI: 10.1021/acscatal.4c06672

Nickel-catalysed enantioselective alkene dicarbofunctionalization enabled by photochemical aliphatic C–H bond activation

Xia Hu, Iván Cheng-Sánchez, Wangqing Kong, Gary A. Molander and Cristina Nevado

Nat Catal, 2024, 7, 655
DOI: 10.1038/s41929-024-01153-0

Ni-catalyzed reductive alkylgermylation of activated alkenes: Modular access to polyfunctionalized alkyl germanes

Yi-Wei Qiao, Bing-Qi Zhou and Yuan Huang

Chem Catalysis, 2023, 3, 100819
DOI: 10.1016/j.checat.2023.100819

Preparation of low-cost biochar from discarded tea waste for aqueous phase removal of hexavalent chromium [Cr(VI)]: kinetics, isotherm, and recyclability analysis

Deepa Kannaujiya, Devesh Vishwakarma and Shikha

Water Practice & Technology, 2024, 19, 2850
DOI: 10.2166/wpt.2024.172