A to Z of polymorphs related by proton transfer

Amy Woods-Ryan, Cheryl L. Doherty and Aurora J. Cruz-Cabeza

CrystEngComm, 2023, 25, 2845
DOI: 10.1039/D3CE00216K

Crystal Structure Prediction of Drug Molecules in the Cloud: A Collaborative Blind Challenge Study

Caitlin C. Bannan, Grigory Ovanesyan, Thomas A. Darden, Alan P. Graves, Colin M. Edge, Luca Russo, Royston C. B. Copley, Eric Manas, A. Geoffrey Skillman, Anthony Nicholls and Hari S. Muddana

Crystal Growth & Design, 2025, 25, 1299
DOI: 10.1021/acs.cgd.4c00572

Aspects of Isostructurality and Polymorphism in a Diverse Group of Monosubstituted Acetanilides

L. Susanne Coles née Huth, Terry L. Threlfall and David S. Hughes

Crystal Growth & Design, 2024, 24, 2552
DOI: 10.1021/acs.cgd.4c00027

Combining Structural Rugosity and Crystal Packing Comparison: A Route to More Polymorphs?

Riccardo Montis, Michael B. Hursthouse, John Kendrick, Jason Howe and Richard J. Whitby

Crystal Growth & Design, 2022, 22, 559
DOI: 10.1021/acs.cgd.1c01132

The cocrystal advantage: overcoming polymorph patent barriers in generic drug development

Raju G. Sharma, Smitkumar D. Vankar and Mayank G. Sharma

Mol Divers, 2025
DOI: 10.1007/s11030-025-11375-4

Real-time polymorphic form assessment of pharmaceuticals at tabletting pressures using micro-scale quantities

Deepak Kakde, Banaz Fetah, Suse S. Bebiano, Martin R. Ward, Cheryl L. Doherty, Daniel Markl and Iain D.H. Oswald

International Journal of Pharmaceutics, 2025, 678, 125707
DOI: 10.1016/j.ijpharm.2025.125707

Enabling Data-Driven Solubility Modeling at GSK: Enhancing Purge Predictions for Mutagenic Impurities

Luigi Da Vià, Matthias Depoortere, Robert D. Willacy, Alastair J. Roberts, Pandian Sokkar, Mathieu Fossépré, Andrew Ruba and Magdalena A. Zwierzyna

Org. Process Res. Dev., 2024, 28, 4215
DOI: 10.1021/acs.oprd.4c00384

Understanding Crystal Structures to Guide Form Selection of Active Pharmaceutical Ingredients: A Case Study of AZD9567

Okky Dwichandra Putra, Jenny Ottosson, Sten O. Nilsson Lill and Anna Pettersen

Crystal Growth & Design, 2022, 22, 535
DOI: 10.1021/acs.cgd.1c01124

A survey of solid form landscape: Trends in occurrence and distribution of various solid forms and challenges in solid form selection

Z. Jane Li, Yue Lu, Ruiping Wang, Xiaomei Dong, Pengyuan Chen, Jie Duan, Meiting Shi, Liyu Wang and Yuan Liu

Journal of Pharmaceutical Sciences, 2025, 114, 586
DOI: 10.1016/j.xphs.2024.10.045

An integrated approach combining experimental, informatics and energetic methods for solid form derisking of PF-06282999

Ghazala Sadiq, Shubham Sharma, Joanna S. Stevens, Pablo Martinez-Bulit, Lily M. Hunnisett, Christopher Cameron, Brian Samas, Emma Hawking, Nicholas Francia, Jeff Lengyel, Elna Pidcock, Sadia Rahman, Matthew Nisbet, Kevin Back, Cheryl Doherty, Patricia Basford, Timothy G. Cooper, Garry O'Connor and Rajni M. Bhardwaj

Journal of Pharmaceutical Sciences, 2025, 114, 371
DOI: 10.1016/j.xphs.2024.10.013

Computational Insights Into New Portulaca oleracea Alkaloids as Potential SARS‐CoV‐2 PLpro Inhibitors

Mohammad G. Al‐Thiabat and Maram B. Alhawarri

Chemistry & Biodiversity, 2026, 23
DOI: 10.1002/cbdv.202502908

Computational Profiling of Monoterpenoid Phytochemicals: Insights for Medicinal Chemistry and Drug Design Strategies

André Nogueira Cardeal dos Santos, Paulo Elesson Guimarães de Oliveira, José Ednésio da Cruz Freire, Sara Araújo dos Santos, José Eduardo Ribeiro Honório Júnior, Claudia Roberta de Andrade, Bruno Lopes de Sousa, Wildson Max Barbosa da Silva, Ariclécio Cunha de Oliveira, Vânia Marilande Ceccatto, José Henrique Leal Cardoso, Adélia Justina Aguiar Aquino and Andrelina Noronha Coelho de Sousa

IJMS, 2025, 26, 7671
DOI: 10.3390/ijms26167671