Ayesha Sarfraz, Rizwan Ashraf, Shaukat Ali, Tugba Taskin-Tok, Zohra Khalid, Sana Ullah, Talha Kahlid, Muhammad Mushtaq, Salah M. El-Bahy and Zeinhom M. El-Bahy

Journal of Molecular Structure, 2022, 1251, 131946
DOI: 10.1016/j.molstruc.2021.131946

Photoinduced Electron Transfer from Xanthates to Acyl Azoliums: Divergent Ketone Synthesis via N‐Heterocyclic Carbene Catalysis

Chang‐Yin Tan, Minseok Kim and Sungwoo Hong

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202306191

Carbene-Catalyzed Esterification for the Synthesis of Inherently Chiral Saddle-Shaped Eight-Membered Lactones

Yao Chen, Xiaoqing Lai, Huan Gong, Hongzhi Zhuang, Yongchang Hu, Yang Xiao, Jianing An, Jianfeng Xu and Xingkuan Chen

Org. Lett., 2025, 27, 12343
DOI: 10.1021/acs.orglett.5c03940

Enones from aldehydes and alkenes by carbene-catalyzed dehydrogenative couplings

Kun Tang, Fen Su, Shijie Pan, Fengfei Lu, Zhongfu Luo, Fengrui Che, Xingxing Wu and Yonggui Robin Chi

Chinese Chemical Letters, 2024, 35, 109495
DOI: 10.1016/j.cclet.2024.109495

Enantioselective Synthesis of C−O Axially Chiral Diaryl Ethers by NHC‐Catalyzed Atroposelective Desymmetrization**

Sayan Shee, Sowmya Shree Ranganathappa, Mahesh S. Gadhave, Romin Gogoi and Akkattu T. Biju

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202311709

N-Heterocyclic Carbene Catalysis for Polycyclic Benzazepines Assembly: Regioselective Intramolecular Tandem Radical Cyclization

Zhiming Feng, Lili Wu, Cong-Ying Zhou and Chengming Wang

Org. Lett., 2024, 26, 9068
DOI: 10.1021/acs.orglett.4c03303

Oxidative Radical NHC Catalysis: Divergent Difunctionalization of Olefins through Intermolecular Hydrogen Atom Transfer

Qing‐Zhu Li, Yan‐Qing Liu, Xin‐Xin Kou, Wen‐Lin Zou, Ting Qi, Peng Xiang, Jin‐Dun Xing, Xiang Zhang and Jun‐Long Li

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202207824

N-Heterocyclic Carbene and Manganese Synergistic Catalysis: A Three-Component Radical Acylmonofluoroalkylation of Alkenes

Feng Liang, Ning Chen, Keguang Cheng and Quande Wang

Org. Lett., 2023, 25, 8168
DOI: 10.1021/acs.orglett.3c03461

Photocatalytic Radical Umpolung for Strain‐Release Difunctionalization of (Aza)bicyclo[1.1.0]butanes

Chang‐Yin Tan, Hyewon Ju, Jinwook Jeong, Jaehun Kim and Sungwoo Hong

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202517231

NHC‐Free Ketone Synthesis via Radical Coupling Mechanisms

Lifeng Wang, Yuxing Cai and Yong Huang

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202500011

Lewis Base‐Catalysed Enantioselective Radical Conjugate Addition for the Synthesis of Enantioenriched Pyrrolidinones

Will C. Hartley, Florian Schiel, Elena Ermini and Paolo Melchiorre

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202204735

Mesoionic carbene-Breslow intermediates as super electron donors: Application to the metal-free arylacylation of alkenes

Wei Liu, Adam Vianna, Zengyu Zhang, Shiqing Huang, Linwei Huang, Mohand Melaimi, Guy Bertrand and Xiaoyu Yan

Chem Catalysis, 2021, 1, 196
DOI: 10.1016/j.checat.2021.03.004

Recent advances in the chemistry and applications of N-heterocyclic carbenes

Peter Bellotti, Maximilian Koy, Matthew N. Hopkinson and Frank Glorius

Nat Rev Chem, 2021, 5, 711
DOI: 10.1038/s41570-021-00321-1

Enantioselective synthesis of inherently chiral pillar[5]arenes via N-heterocyclic carbene catalysis

Mei An, Fei Xie, Zhi-Bin Zhao, Qiu-Shuang Fu, Chuan-Jun Lu, Jia Feng and Ren-Rong Liu

Chinese Chemical Letters, 2026, 112617
DOI: 10.1016/j.cclet.2026.112617

Carbene-Catalyzed Alkylation of Carboxylic Esters via Direct Photoexcitation of Acyl Azolium Intermediates

Shi-Chao Ren, Wen-Xin Lv, Xing Yang, Jia-Lei Yan, Jun Xu, Fang-Xin Wang, Lin Hao, Huifang Chai, Zhichao Jin and Yonggui Robin Chi

ACS Catal., 2021, 11, 2925
DOI: 10.1021/acscatal.1c00165

A Quadruple Catalysis Enabling Intermolecular Branch‐Selective Hydroacylation of Styrenes

Yunosuke Takekawa, Masanari Nakagawa, Kazunori Nagao and Hirohisa Ohmiya

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202301484

Radical Chemistry of Photoexcitable Borates

Yuto Sumida and Hirohisa Ohmiya

J. Synth. Org. Chem. Jpn., 2024, 82, 367
DOI: 10.5059/yukigoseikyokaishi.82.367

Oxidative N-heterocyclic carbene (NHC) catalysis for the rapid access to functionalized pyrrolo-oxazinones

Arghya Ghosh, Shilpa Barik, Soumen Barik, Sayan Shee and Akkattu T. Biju

Tetrahedron, 2021, 94, 132330
DOI: 10.1016/j.tet.2021.132330

Persistent Radicals Derived from N-Heterocyclic Carbenes for Material Applications

Hayoung Song, Ewa Pietrasiak and Eunsung Lee

Acc. Chem. Res., 2022, 55, 2213
DOI: 10.1021/acs.accounts.2c00222

Aroyl Fluorides as Bifunctional Reagents for Dearomatizing Fluoroaroylation of Benzofurans

Xiaoye Yu, Qing-Yuan Meng, Constantin G. Daniliuc and Armido Studer

J. Am. Chem. Soc., 2022, 144, 7072
DOI: 10.1021/jacs.2c01735

N-Heterocyclic Carbene-Catalyzed Synthesis of Pentafluorophenyl Sulfides

Dengpeng Xia, Jinyun Luo, Lin He, Zhihua Cai and Guangfen Du

Chinese Journal of Organic Chemistry, 2024, 44, 622
DOI: 10.6023/cjoc202306014

C(sp3)–H Carboxylation via Carbene/Photoredox Cooperative Catalysis

Cullen R. Schull, Jing Cao, Sophia R. Mitton-Fry, Mara Mrksich and Karl A. Scheidt

ACS Catal., 2025, 15, 1287
DOI: 10.1021/acscatal.4c06791

Aminoacylation of Alkenes by Cooperative NHC and Photoredox Catalysis

Lena Lezius, Jannik Reimler, Nadine Döben, Michael Hamm, Constantin G. Daniliuc and Armido Studer

Synlett, 2024, 35, 445
DOI: 10.1055/a-2145-8697

Enantioselective Relay Coupling of Perfluoroalkyl and Vinylogous Ketyl Radicals

Yuxin Zhao, Yichi Zhang and Yong Huang

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202409566

Cooperative NHC and Photoredox-Catalyzed Radical Azidoacylation of Alkenes to β-Amino Ketones

Jiannan Zhao, Wen-Deng Liu and Congjin Zhang

Org. Lett., 2025, 27, 7620
DOI: 10.1021/acs.orglett.5c02183

Singly and doubly oxidized carbenes and their applications in catalysis

Alexis K. Day, Mehdi Abdellaoui, Michèle Soleilhavoup and Guy Bertrand

Chem Catalysis, 2025, 5, 101159
DOI: 10.1016/j.checat.2024.101159

Stereoselective Fluoroalkylacylation of Alkynes via Cooperative N-Heterocyclic Carbene/Palladium Catalysis

Ying Huang, Xin-Han Wang, Chun-Lin Zhang and Song Ye

Org. Lett., 2024, 26, 3441
DOI: 10.1021/acs.orglett.4c00875

γ-C(sp3)-H acylation of aliphatic amines enabled by cooperative photoredox NHC/Pd catalysis

Xin-Han Wang, Ying Huang, Chun-Lin Zhang and Song Ye

Chinese Chemical Letters, 2026, 37, 111484
DOI: 10.1016/j.cclet.2025.111484

Radical Coupling Initiated by Organophosphine Addition to Ynoates

Jing Cao, Antonia Seitz, José A. Forni, Anastasios Polyzos and David W. Lupton

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202303869

N‐Heterocyclic Carbene/Transition Metal Dual Catalysis

Zhao‐Fei Zhang, Chun‐Lin Zhang and Song Ye

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202402259

Visible-light-induced N-heterocyclic carbene mediated cascade transformation of N-alkenoxypyridinium salts

He Sheng, Qiang Liu, Fei Chen, Zhixiang Wang and Xiangyu Chen

Chinese Chemical Letters, 2022, 33, 4298
DOI: 10.1016/j.cclet.2022.01.028

Photoredox decarboxylative acylation of carboxylic acid by 4-acyl-1,2,3-triazoliums

Zengyu Zhang, Shiqing Huang, Fan Gao, Guangyin Lu and Xiaoyu Yan

Green Synthesis and Catalysis, 2024
DOI: 10.1016/j.gresc.2024.10.004

Acyl Azolium–Photoredox-Enabled Synthesis of β-Keto Sulfides

Michael J. Rourke, Charles T. Wang, Cullen R. Schull and Karl A. Scheidt

ACS Catal., 2023, 13, 7987
DOI: 10.1021/acscatal.3c01558

Ketones from aldehydes via alkyl C(sp3)−H functionalization under photoredox cooperative NHC/palladium catalysis

Hai-Ying Wang, Xin-Han Wang, Bang-An Zhou, Chun-Lin Zhang and Song Ye

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-39707-8

N-Heterocyclic-Carbene-Catalyzed Imine Umpolung for the Cross-Coupling of Quinoxalin-2-ones with Isatins

Shilpa Barik, Anusree A. Kunhiraman, Rohan Chandra Das and Akkattu T. Biju

JACS Au, 2025, 5, 948
DOI: 10.1021/jacsau.4c01166

α‐Acylation of Alkenes by a Single Photocatalyst

Yuan‐Yuan Cheng, Hong‐Yu Hou, Yu Liu, Ji‐Xin Yu, Bin Chen, Chen‐Ho Tung and Li‐Zhu Wu

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202208831

Photochemical reduction of acylimidazolium salts

Michael Jakob, Nick Bechler, Hassan Abdelwahab, Fabian Weber, Janos Wasternack, Leonardo Kleebauer, Jan P Götze and Matthew N Hopkinson

Beilstein J. Org. Chem., 2025, 21, 1973
DOI: 10.3762/bjoc.21.153

Regioselective Radical 1,4-Difunctionalization of 1,3-Cyclohexadiene via NHC Catalysis

Yiwen Yin, Jianquan Feng, Liya Wang, Hao Zhang and Ding Du

Org. Lett., 2025, 27, 13055
DOI: 10.1021/acs.orglett.5c04221

Organocatalytic Three-Component Acyldifluoromethylation of Vinylarenes via N-Heterocyclic Carbene-Catalyzed Radical Relay

Kun She, Feng Liang, Shichao Tian, Hengshan Wang, Gavin Chit Tsui and Quande Wang

Org. Lett., 2022, 24, 4840
DOI: 10.1021/acs.orglett.2c02093

Access to β-Keto Amino Acid Derivatives via Interrupted Polonovski Strategy Involving NHC-Catalyzed Aza Benzoin Reaction

Bhabani Sankar Dehury, Soumen Barik, Ganga Sankar and Akkattu T. Biju

Org. Lett., 2024, 26, 10690
DOI: 10.1021/acs.orglett.4c03505

Atroposelective Synthesis of N–N Axially Chiral Indoles and Pyrroles via NHC-Catalyzed Diastereoselective (3 + 3) Annulation Strategy

Sowmya Shree Ranganathappa, Bhabani Sankar Dehury, Gautam Kumar Singh, Sayan Shee and Akkattu T. Biju

ACS Catal., 2024, 14, 6965
DOI: 10.1021/acscatal.4c00513

Light-Driven N-Heterocyclic Carbene Catalysis Using Alkylborates

Yukiya Sato, Yamato Goto, Kei Nakamura, Yusuke Miyamoto, Yuto Sumida and Hirohisa Ohmiya

ACS Catal., 2021, 11, 12886
DOI: 10.1021/acscatal.1c04153

Asymmetric Synthesis of Benzofuranones with a C3 Quaternary Center via an Addition/Cyclization Cascade Using Noncovalent N-Heterocyclic Carbene Catalysis

Ujjwal Maji, Supriyo Das, Arpita Baidya, Ishita Roy and Joyram Guin

Org. Lett., 2024, 26, 8719
DOI: 10.1021/acs.orglett.4c03014

Oxidative Quenching-Enabled, NHC-Catalyzed Diastereoselective Aminoacylation of (Z/E)-β-Methylstyrenes with Benzoyl Saccharin

Mingrui Li, Xiao Song, Jiuli Xia, Xueyun Lu, Jiaqiong Sun, Yan Li, Guangfan Zheng, Tao Xiong and Qian Zhang

Org. Lett., 2026, 28, 1221
DOI: 10.1021/acs.orglett.5c04959

Bifunctional NHC-Catalyzed Asymmetric Intramolecular Conjugate Addition via Noncovalent Interaction

Ujjwal Maji, Arpita Baidya, Supriyo Das and Joyram Guin

Org. Lett., 2025, 27, 2423
DOI: 10.1021/acs.orglett.5c00315

Catalytic N‐Acylation of Cyclic Amines by Arylglyoxylic Acids via Radical‐Radical Cross‐Coupling

Ajijur Rahaman, Anupam Kumar Singh, Aniket Gupta and Sukalyan Bhadra

Eur J Org Chem, 2021, 2021, 2198
DOI: 10.1002/ejoc.202100381

N‐Heterocyclic Carbene Enabled Functionalization of Inert C(Sp3)−H Bonds via Hydrogen Atom Transfer (HAT) Processes

Fengfei Lu, Fen Su, Shijie Pan, Xiuli Wu, Xingxing Wu and Yonggui Robin Chi

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202401811

Atroposelective Access to 1,3‐Oxazepine‐Containing Bridged Biaryls via Carbene‐Catalyzed Desymmetrization of Imines

Xing Yang, Liwen Wei, Yuelin Wu, Liejin Zhou, Xinglong Zhang and Yonggui Robin Chi

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202211977

Catalyst Control over S(IV)-stereogenicity via Carbene-derived Sulfinyl Azolium Intermediates

Benpeng Li, Junyuan Hu, Minghong Liao, Qin Xiong, Yaqi Zhang, Yonggui Robin Chi, Xinglong Zhang and Xingxing Wu

J. Am. Chem. Soc., 2024, 146, 25350
DOI: 10.1021/jacs.4c10486

Light‐Driven Carbene Catalysis for the Synthesis of Aliphatic and α‐Amino Ketones

Anna V. Bay, Keegan P. Fitzpatrick, Gisela A. González‐Montiel, Abdikani Omar Farah, Paul Ha‐Yeon Cheong and Karl A. Scheidt

Angewandte Chemie, 2021, 133, 18069
DOI: 10.1002/ange.202105354

Organophosphites: An Addition to the Arsenal of Organocatalysts

Nilofar Baral, Soniya Rani, Pinku Saikia and Pradip Maity

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202201238

Synergistic Visible Light Photocatalysis with Organocatalysis

Jia‐Hao Shen, Min Shi and Yin Wei

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202301157

Transition-metal-free tandem cyclization by radical NHC catalysis: Rapid access to indolo[2,1‑a]isoquinolines

Shuoqi Wang and Chengming Wang

Tetrahedron Letters, 2024, 151, 155319
DOI: 10.1016/j.tetlet.2024.155319

Radical NHC Organocatalysis: Enabling Ultra-Remote, Site-Selective Functionalization of Arene C–H Bonds

Xiang Zhang, Rong Zeng, Wan-Cong Liu, Qing-Zhu Li and Jun-Long Li

Synlett, 2025, 36, 1939
DOI: 10.1055/a-2597-0098

γ-Difluoroalkylation: Synthesis of γ-Difluoroalkyl-α,β-Unsaturated Esters via Photoredox NHC-Catalyzed Radical Reaction

Lei Dai, Yuan-Yuan Xu, Zi-Hao Xia and Song Ye

Org. Lett., 2020, 22, 8173
DOI: 10.1021/acs.orglett.0c03208

Iminoacylation of Alkenes via Photoredox N-Heterocyclic Carbene Catalysis

Yi-Xiong Dong, Chun-Lin Zhang, Zhong-Hua Gao and Song Ye

Org. Lett., 2023, 25, 855
DOI: 10.1021/acs.orglett.3c00006

Alkynyl Acylazolium: A Versatile 1,3‐Bielectrophilic 3C‐Synthon in NHC‐Organocatalysis

Jian Gao, Simiao Zhang and Ding Du

The Chemical Record, 2023, 23
DOI: 10.1002/tcr.202300046

Organocatalytic Three-Component 1,2-Cyanoalkylacylation of Alkenes via Radical Relay

Yu Gao, Yusheng Quan, Zhenjiang Li, Luoyu Gao, Zhihao Zhang, Xin Zou, Rui Yan, Yuanyuan Qu and Kai Guo

Org. Lett., 2021, 23, 183
DOI: 10.1021/acs.orglett.0c03907

Remote C(sp3)−H Acylation of Amides and Cascade Cyclization via N‐Heterocyclic Carbene Organocatalysis

Qing‐Zhu Li, Rong Zeng, Yang Fan, Yan‐Qing Liu, Ting Qi, Xiang Zhang and Jun‐Long Li

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202116629

N-heterocyclic carbene- and organic photoredox-catalysed meta-selective acylation of electron-rich arenes

Yamato Goto, Masaki Sano, Yuto Sumida and Hirohisa Ohmiya

Nat. Synth, 2023, 2, 1037
DOI: 10.1038/s44160-023-00378-4

The cascade annulation approach to quinoxalines by radical NHC catalysis

Tinglan Liu and Chengming Wang

Green Synthesis and Catalysis, 2025
DOI: 10.1016/j.gresc.2025.04.011

Critical Assessment of the Reducing Ability of Breslow‐type Derivatives and Implications for Carbene‐Catalyzed Radical Reactions**

Ludivine Delfau, Samantha Nichilo, Florian Molton, Julie Broggi, Eder Tomás‐Mendivil and David Martin

Angew Chem Int Ed, 2021, 60, 26783
DOI: 10.1002/anie.202111988

Catalytic Reductive Homocoupling of Benzyl Chlorides Enabled by Zirconocene and Photoredox Catalysis

Ryota Tajima, Keisuke Tanaka, Kazuhiro Aida, Eisuke Ota and Junichiro Yamaguchi

Precision Chemistry, 2025, 3, 43
DOI: 10.1021/prechem.4c00077

Enantioselective Amination of 3‐Substituted‐2‐benzofuranones via Non‐covalent N‐Heterocyclic Carbene Catalysis

Bhaskar Deb Mondal, Sadhan Gorai, Rounak Nath, Ankan Paul and Joyram Guin

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202303115

Catalytic Activation of Acceptor–Acceptor Bicyclobutanes Enabled by Lewis Base Catalysis

Jin‐Lan Zhou, Xuan Zhan, Heng‐Xian He, Youzhi Xu, Quanxin Peng, Genping Huang and Jian‐Jun Feng

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202507590

Dual visible-light and NHC-catalyzed radical relay trifunctionalization of unactivated alkenes

Jian-Quan Feng, Luning Li, Jingyi Wang, Aoting Ni, Zexuan Wei, Ding Du and Jie Feng

Chem Synth, 2023, 3
DOI: 10.20517/cs.2023.43

Recent advances in transition-metal-free conversion of aldehydes to ketones

Yike Bai, Wenhua Yu, Rong Chen, Guipeng Yu and Baosheng Wei

Green Synthesis and Catalysis, 2025, 6, 239
DOI: 10.1016/j.gresc.2024.04.007

Radical Coupling Initiated by Organophosphine Addition to Ynoates

Jing Cao, Antonia Seitz, José A. Forni, Anastasios Polyzos and David W. Lupton

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202303869

N-Heterocyclic Carbene-Catalyzed 1,4-Alkylacylation of 1,3-Enynes

Yuxing Cai, Jiean Chen and Yong Huang

Org. Lett., 2021, 23, 9251
DOI: 10.1021/acs.orglett.1c03601

Dynamic Kinetic Resolution Approach to C–O Axially Chiral Benzonitriles via N-Heterocyclic Carbene-Catalyzed Atroposelective Imine Umpolung

Sayan Shee, Darshini Ramachandran, Romin Gogoi and Akkattu T. Biju

ACS Catal., 2025, 15, 13157
DOI: 10.1021/acscatal.5c04159

N-Heterocyclic Carbene-Catalyzed Four-Component Reaction: Chemoselective Cradical-Cradical Relay Coupling Involving the Homoenolate Intermediate

Zhen Li, Meirong Huang, Xinhao Zhang, Jiean Chen and Yong Huang

ACS Catal., 2021, 11, 10123
DOI: 10.1021/acscatal.1c02576

N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Carbocycle-Fused Uracils via Formal [4 + 2] Annulation/Lactone Formation/Decarboxylation Cascade

Chen Lin, Simiao Zhang, Jingyi Wang, Lei Chen, Yiwei Zhu and Ding Du

Org. Lett., 2022, 24, 3631
DOI: 10.1021/acs.orglett.2c01165

NHC-catalyzed [3 + 4] annulation between 2-dromoenal and aryl 1,2-diamine: Insights into mechanisms, chemo and stereoselectivities

Zhilin Li, Yan Li, Zhiyi Song and Zhiqiang Zhang

Molecular Catalysis, 2022, 530, 112604
DOI: 10.1016/j.mcat.2022.112604

Enantioselective Transformation of Hydrazones via Remote NHC Catalysis: Activation Across C═N and N–N Bonds

Jiamiao Jin, Ya Lv, Wenli Tang, Kunpeng Teng, Yixian Huang, Jingxin Ding, Tingting Li, Guanjie Wang and Yonggui Robin Chi

ACS Catal., 2024, 14, 18378
DOI: 10.1021/acscatal.4c06029

N-Heterocyclic Carbene-Catalyzed Atroposelective Synthesis of N–N Axially Chiral 3-Amino Quinazolinones

Kuruva Balanna, Soumen Barik, Shilpa Barik, Sayan Shee, Niket Manoj, Rajesh G. Gonnade and Akkattu T. Biju

ACS Catal., 2023, 13, 8752
DOI: 10.1021/acscatal.3c01709

Homologation of Ketones: Direct Transformation of Alkyl Ketones to Aryl Ketones via Photoredox Catalyzed Deacylation-Aroylation Sequence

Tian Wang, Zengyu Zhang, Fan Gao and Xiaoyu Yan

Org. Lett., 2024, 26, 6915
DOI: 10.1021/acs.orglett.4c02576

Radical NHC Catalysis

Kun Liu, Max Schwenzer and Armido Studer

ACS Catal., 2022, 12, 11984
DOI: 10.1021/acscatal.2c03996

Aryl radical-mediated N-heterocyclic carbene catalysis

Yuki Matsuki, Nagisa Ohnishi, Yuki Kakeno, Shunsuke Takemoto, Takuya Ishii, Kazunori Nagao and Hirohisa Ohmiya

Nat Commun, 2021, 12
DOI: 10.1038/s41467-021-24144-2

Regioselective Alkylacylation of 1,3-Dienes by Merging N-Heterocyclic Carbene Catalysis with Photoinduced Palladium Catalysis

Ying Huang, You-Feng Han, Chun-Lin Zhang and Song Ye

Org. Lett., 2025, 27, 415
DOI: 10.1021/acs.orglett.4c04453

Synthesis of Cyclohexanones by a Tandem Photocatalyzed Annulation

Anna V. Bay, Emelia J. Farnam and Karl A. Scheidt

J. Am. Chem. Soc., 2022, 144, 7030
DOI: 10.1021/jacs.1c13105

Enantioselective acyl-trifluoromethylation of olefins by bulky thiazolium carbene catalysis

Sripati Jana, Matthew D. Wodrich and Nicolai Cramer

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-58423-z

Enantioselective Synthesis of 5,6-Dihydroindolizines by N-Heterocyclic Carbene (NHC)-Catalyzed Core-Structure-Inspired Strategy of Azolium–Enolate Cascade

Arghya Ghosh, Sayan Shee, Shilpa Barik, Rajesh G. Gonnade and Akkattu T. Biju

Org. Lett., 2021, 23, 5223
DOI: 10.1021/acs.orglett.1c01761

1,4-Alkylcarbonylation of 1,3-Enynes to Access Tetra-Substituted Allenyl Ketones via an NHC-Catalyzed Radical Relay

Lei Chen, Chen Lin, Simiao Zhang, Xiaojin Zhang, Jianming Zhang, Lianjie Xing, Yage Guo, Jie Feng, Jian Gao and Ding Du

ACS Catal., 2021, 11, 13363
DOI: 10.1021/acscatal.1c03861

Highly enantioselective carbene-catalyzed δ-lactonization via radical relay cross-coupling

Yuhan Liu, Jingyang Zhang, Gongming Yang and Jian Wang

Chinese Chemical Letters, 2025, 36, 109790
DOI: 10.1016/j.cclet.2024.109790

NHC-Catalyzed Reaction of Aldehydes for C(sp2)–O Bond Formation

Yousuke Yamaoka and Hideto Miyabe

Catalysts, 2024, 14, 219
DOI: 10.3390/catal14040219

Synthesis of Functionalized Dihydrocoumarins by NHC-Catalyzed [3 + 3] Annulation of Enals with 2-Substituted Naphthoquinones

Sayan Shee, Soumen Barik, Arghya Ghosh and Akkattu T. Biju

Org. Lett., 2021, 23, 8039
DOI: 10.1021/acs.orglett.1c03059

Photobiocatalytic Reaction: From Single Component to Triple Components

Rui‐Tao Sun, Peng Chen, Sheng‐Zhen Xu, Liang‐Qiu Lu and Wen‐Jing Xiao

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202502489

N-Heterocyclic Carbene (NHC)-Catalyzed Desymmetrization of Biaryldialdehydes to Construct Axially Chiral Aldehydes

Wei Zhao, Jing Liu, Xiangkui He, Hao Jiang, Liangqiu Lu and Wenjing Xiao

Chinese Journal of Organic Chemistry, 2022, 42, 2504
DOI: 10.6023/cjoc202203048

Enantioselective Synthesis of Axially Chiral Diaryl Ethers via NHC Catalyzed Desymmetrization and Following Resolution

Bang‐An Zhou, Xue‐Ning Li, Chun‐Lin Zhang, Zhi‐Xiang Wang and Song Ye

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202314228

Atroposelective Construction of C─B Axial Chirality via N‐Heterocyclic Carbene‐Catalyzed Dynamic Kinetic Resolution

Ying Huang, Xue‐Ning Li, Xin‐Han Wang, Zhi‐Xiang Wang, Song Ye and Chun‐Lin Zhang

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202501991

Phosphonylacylation of Alkenes Enabled by Visible-Light-Induced N-Heterocyclic Carbene Catalysis

Ming-Lei Jin, Yi-Xiong Dong, Zhong-Hua Gao and Song Ye

Org. Lett., 2024, 26, 1711
DOI: 10.1021/acs.orglett.4c00242

Synthetic Advantages of Defluorinative C−F Bond Functionalization

Leidy V. Hooker and Jeffrey S. Bandar

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202308880

Recent progress in carbene-catalyzed fluoroalkylation

Bei Zhang, Xuan Zhang and Jian Wang

Sci. China Chem., 2024, 67, 2448
DOI: 10.1007/s11426-024-1981-1

Breslow-type intermediates as super electron donors in 3-component coupling reactions

John A. Murphy

Chem Catalysis, 2021, 1, 26
DOI: 10.1016/j.checat.2021.04.004

Diastereoselective Aminoacylation of β-Methylstyrenes through Cooperative N-Heterocyclic Carbene and Photoredox Catalysis

Chuyu Xiao, Wen-Deng Liu, Jiyuan Gao and Jiannan Zhao

Org. Lett., 2026, 28, 697
DOI: 10.1021/acs.orglett.5c04822

Exploring Molecular Complexity by N‐Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity

Yonggui Liu, Yanyan Wang, Xingxing Wu and Yonggui Robin Chi

The Chemical Record, 2023, 23
DOI: 10.1002/tcr.202200219

Metal-free 2-isocyanobiaryl-based cyclization reactions: phenanthridine framework synthesis

Fatemeh Doraghi, Ali Amini, Mehdi Ghanbarlou, Bagher Larijani and Mohammad Mahdavi

Mol Divers, 2024, 28, 419
DOI: 10.1007/s11030-023-10743-2

Gauging Radical Stabilization with Carbenes

Kevin Breitwieser, Hilke Bahmann, Robert Weiss and Dominik Munz

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202206390

N-Heterocyclic Carbene-Based Catalysis Enabling Cross-Coupling Reactions

Hirohisa Ohmiya

ACS Catal., 2020, 10, 6862
DOI: 10.1021/acscatal.0c01795

Radical Reactions with N-Heterocyclic Carbene (NHC)-Derived Acyl Azoliums for Access to Multifunctionalized Ketones

Hui Cai, Xiaoqun Yang, Shi-Chao Ren and Yonggui Robin Chi

ACS Catal., 2024, 14, 8270
DOI: 10.1021/acscatal.4c01973

β,γ-trans-selective γ-butyrolactone formation via homoenolate cross-annulation of enals and aldehydes catalyzed by sterically hindered N-heterocyclic carbene

Ryuji Kyan, Yuya Kitagawa, Ryuji Ide, Kohei Sato, Nobuyuki Mase and Tetsuo Narumi

Tetrahedron, 2021, 91, 132191
DOI: 10.1016/j.tet.2021.132191

Theoretical investigation of a [4+2] annulation reaction of an enal with an ynamide under NHC/Au dual catalysis: mechanism and origin of stereoselectivity

Sai-Bo Cao, Pingxin Liang, Gai-Ling Huang and Yang Wang

Molecular Catalysis, 2025, 585, 115363
DOI: 10.1016/j.mcat.2025.115363

Deconstructive Radical–Radical Coupling for Programmable Remote Acylation

Jing Cao, Cullen R. Schull and Karl A. Scheidt

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202507542

Single‐Electron Transfer Reactions Enabled by N‐Heterocyclic Carbene Organocatalysis

Qing‐Zhu Li, Rong Zeng, Bo Han and Jun‐Long Li

Chemistry A European J, 2021, 27, 3238
DOI: 10.1002/chem.202004059

Revisiting the Reaction of IPr with Tritylium: An Alternative Mechanistic Pathway**

Hayoung Song and Eunsung Lee

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202203364

Electroredox N-Heterocyclic Carbene-Catalyzed Enantioselective (3 + 3) Annulation of Enals with 2-Naphthols

Vikas Kale, Sayan Shee, Shiv Dutt, Nidhi Sinha, Akkattu T. Biju and Prabal Banerjee

Org. Lett., 2025, 27, 57
DOI: 10.1021/acs.orglett.4c03879

N-Heterocyclic Carbene Catalysis for Facile Access to Pentasubstituted 4H-Pyran Derivatives

Xiaolin Peng, Yulin Wang, Yixian Huang, Sheng Zhang, Zhichao Jin and Shi-Chao Ren

Synlett, 2024, 35, 1185
DOI: 10.1055/a-2253-4365

Direct Acylation of Unactivated Alkyl Halides with Aldehydes through N‐Heterocyclic Carbene Organocatalysis

Qing‐Zhu Li, Rong Zeng, Peng‐Shuai Xu, Xin‐Hang Jin, Chuan Xie, Qi‐Chun Yang, Xiang Zhang and Jun‐Long Li

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202309572

Metal-Free Generation of γ-Cyanoalkyl Radicals by N-Heterocyclic Carbene Catalysis: Assembly of 6-Cyanoalkyl Phenanthridines

Qianrong Li, Cong-Ying Zhou and Chengming Wang

Org. Lett., 2022, 24, 9243
DOI: 10.1021/acs.orglett.2c03808

C–C Bond Acylation of Oxime Ethers via NHC Catalysis

Hai-Bin Yang and Dan-Hong Wan

Org. Lett., 2021, 23, 1049
DOI: 10.1021/acs.orglett.0c04248

Mesoionic Carbene‐Catalyzed Formyl Alkylation of Aldehydes

Chang Liu, Zengyu Zhang, Liang‐Liang Zhao, Guy Bertrand and Xiaoyu Yan

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202303478

Theoretical study of [3 + 3] annulation reaction of bromoenal with β-tetralone catalysed by N-heterocyclic carbene

Zhiyi Song, Zhiqiang Zhang and Yan Li

Molecular Physics, 2025, 123
DOI: 10.1080/00268976.2024.2358162

α‐Acylation of Alkenes by a Single Photocatalyst

Yuan‐Yuan Cheng, Hong‐Yu Hou, Yu Liu, Ji‐Xin Yu, Bin Chen, Chen‐Ho Tung and Li‐Zhu Wu

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202208831

Radical Acylation of Alkenes by NHC‐Organocatalysis

Qian Tang, Ding Du and Jian Gao

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202300832

Remote site-selective arene C–H functionalization enabled by N-heterocyclic carbene organocatalysis

Qing-Zhu Li, Wen-Lin Zou, Zhao-Yuan Yu, Xin-Xin Kou, Yan-Qing Liu, Xiang Zhang, Yu He and Jun-Long Li

Nat Catal, 2024, 7, 900
DOI: 10.1038/s41929-024-01194-5

What are the Quenching Processes in Photocatalyzed Reductive N‐Heterocyclic Carbene Organocatalysis?

Fan Gao and Xiaoyu Yan

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.70311

Organocatalytic C−H Functionalization of Simple Alkanes

Fen Su, Fengfei Lu, Kun Tang, Xiaokang Lv, Zhongfu Luo, Fengrui Che, Hongyan Long, Xingxing Wu and Yonggui Robin Chi

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202310072

Lewis Base‐Catalysed Enantioselective Radical Conjugate Addition for the Synthesis of Enantioenriched Pyrrolidinones

Will C. Hartley, Florian Schiel, Elena Ermini and Paolo Melchiorre

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202204735

Energy-Transfer-Enabled Radical Acylation Using Free Alkyl Boronic Acids through Photo and NHC Dual Catalysis

Wan-Cong Liu, Xiang Zhang, Lin Chen, Rong Zeng, Yuan-Hang Tian, En-Dian Ma, Ya-Peng Wang, Bin Zhang and Jun-Long Li

ACS Catal., 2024, 14, 3181
DOI: 10.1021/acscatal.3c06027

NHC‐Catalyzed Enantioselective Transformations Involving α‐Bromoenals

Fatemeh Doraghi, Mahmoud Ameli, Shirin Ansariashlaghi, Bagher Larijani and Mohammad Mahdavi

The Chemical Record, 2024, 24
DOI: 10.1002/tcr.202400005

Interrupted N-Heterocyclic Carbene-Catalyzed Radical Coupling Strategy: A Versatile Platform for Alkylation and Arylation of [60]Fullerene

Di Chao, Tong-Xin Liu, Pengling Zhang, Shilu Xia, Panting Yang, Mengjiao Huang, Qingfeng Liu and Guisheng Zhang

Org. Lett., 2024, 26, 1432
DOI: 10.1021/acs.orglett.4c00043

Carbene‐Catalyzed Asymmetric Construction of Atropisomers

Runjiang Song, Yongtao Xie, Zhichao Jin and Yonggui Robin Chi

Angew Chem Int Ed, 2021, 60, 26026
DOI: 10.1002/anie.202108630

Enantioselective Synthesis of δ-Carbolinones via N-Heterocyclic Carbene Catalysis

Simiao Zhang, Chen Lin, Chaolei Liu and Ding Du

J. Org. Chem., 2022, 87, 10441
DOI: 10.1021/acs.joc.2c00952

Synthesis of β-Ketonitriles via N-Heterocyclic-Carbene-Catalyzed Radical Coupling of Aldehydes and Azobis(isobutyronitrile)

Jiao-Mei Wang, Teng Chen, Chang-Sheng Yao and Kai Zhang

Org. Lett., 2023, 25, 3325
DOI: 10.1021/acs.orglett.3c01168

Enantioselective Synthesis of C−O Axially Chiral Diaryl Ethers by NHC‐Catalyzed Atroposelective Desymmetrization**

Sayan Shee, Sowmya Shree Ranganathappa, Mahesh S. Gadhave, Romin Gogoi and Akkattu T. Biju

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202311709

Deconstructive Radical–Radical Coupling for Programmable Remote Acylation

Jing Cao, Cullen R. Schull and Karl A. Scheidt

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202507542

N‐Heterocyclic Carbene‐Catalyzed Diastereoselective Radical Ring Opening of Bicyclobutanes to 1,1,3,3‐Tetrasubstituted Cyclobutanes

Di Yang and Min Chen

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202500286

Dual Catalysis Relay: Coupling of Aldehydes and Alkenes Enabled by Visible-Light and NHC-Catalyzed Cross-Double C–H Functionalizations

Ming-Shang Liu, Lin Min, Bi-Hong Chen and Wei Shu

ACS Catal., 2021, 11, 9715
DOI: 10.1021/acscatal.1c02890

Nucleophilic Acylation–Annulation Cascade of 2-Chlorobenzonitriles Using Aldehydes Triggered by N-Heterocyclic Carbenes

Mahesh S. Gadhave, Soumen Barik, Felix Wessels and Akkattu T. Biju

Org. Lett., 2023, 25, 8314
DOI: 10.1021/acs.orglett.3c03376

Catalytic construction of non-carbon stereocenters by N-heterocyclic carbenes

Xiaoqing Lai, Yao Chen, Hongzhi Zhuang, Huan Gong, Yongchang Hu and Xingkuan Chen

Discov. Chem., 2026, 3
DOI: 10.1007/s44371-026-00606-8

Historical and recent advances in enantioselective NHC-catalyzed radical reactions

Jia Song, Shi-Chao Ren, Yingguo Liu and Yonggui Robin Chi

Chem Catalysis, 2025, 5, 101398
DOI: 10.1016/j.checat.2025.101398

Cooperative NHC and Photoredox Catalysis for the Synthesis of β‐Trifluoromethylated Alkyl Aryl Ketones

Qing‐Yuan Meng, Nadine Döben and Armido Studer

Angew Chem Int Ed, 2020, 59, 19956
DOI: 10.1002/anie.202008040

Cooperative NHC and Photoredox Dual Catalysis for the Construction of Carbonyl Compounds

Vasudevan Dhayalan

ACS Omega, 2026
DOI: 10.1021/acsomega.5c08569

Synthesis of Highly Congested Tertiary Alcohols via the [3,3] Radical Deconstruction of Breslow Intermediates

Roger Machín Rivera, Nikolas R. Burton, Luke D. Call, Marshall A. Tomat and Vincent N. G. Lindsay

Org. Lett., 2022, 24, 4275
DOI: 10.1021/acs.orglett.2c01627

Synthesis of Pyrroloindolines via N-Heterocyclic Carbene Catalyzed Dearomative Amidoacylation of Indole Derivatives

Hanyu Shu, Jia-Nan Mo, Wen-Deng Liu and Jiannan Zhao

Org. Lett., 2023, 25, 8677
DOI: 10.1021/acs.orglett.3c03588

N-Heterocyclic carbene (NHC)-catalyzed cross-coupling of glycosyl bromides and aldehydes for highly stereoselective synthesis of C-acyl glycosides

Fengfei Lu, Pingping Xiong, WMWW Kandegama, Benpeng Li and Xingxing Wu

Chinese Chemical Letters, 2026, 112745
DOI: 10.1016/j.cclet.2026.112745

Enantioselective functionalization at the C4 position of pyridinium salts through NHC catalysis

Hangyeol Choi, Gangadhar Rao Mathi, Seonghyeok Hong and Sungwoo Hong

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-29462-7

Silylacylation of Alkenes through N-Heterocyclic Carbene Catalysis

Huiwei Xu, Wanyao Zheng, Wen-Deng Liu, Yuqiao Zhou, Luqing Lin and Jiannan Zhao

Org. Lett., 2023, 25, 5579
DOI: 10.1021/acs.orglett.3c01840

Photobiocatalytic Reaction: From Single Component to Triple Components

Rui‐Tao Sun, Peng Chen, Sheng‐Zhen Xu, Liang‐Qiu Lu and Wen‐Jing Xiao

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202502489

N-Heterocyclic carbene catalyzed C-acylation reaction for access to linear aminoenones

Jie Lv, Yingling Nong, Kai Chen, Qingyun Wang, Jiamiao Jin, Tingting Li, Zhichao Jin and Yonggui Robin Chi

Chinese Chemical Letters, 2023, 34, 107570
DOI: 10.1016/j.cclet.2022.05.084

Kooperative NHC‐ und Photoredox‐Katalyse zur Synthese β‐trifluormethylierter Alkylarylketone

Qing‐Yuan Meng, Nadine Döben and Armido Studer

Angewandte Chemie, 2020, 132, 20129
DOI: 10.1002/ange.202008040

NHC-Mediated Radical Acylation Catalyzed by Thiamine- and Flavin-Dependent Enzymes

Shunsuke Kato, Shuto Fujisawa, Yuto Adachi, Mitsuhiro Bandai, Yutaro Mori, Seiji Mori, Tomokazu Shirai and Takashi Hayashi

J. Am. Chem. Soc., 2025, 147, 14837
DOI: 10.1021/jacs.5c04484

Cooperative NHC and Photoredox Catalyzed Deaminative Acylation of Primary Amines via Isonitrile Formation

Shengbin Sun, Jia-Nan Mo, Huiwei Xu, Xiang Li and Jiannan Zhao

Org. Lett., 2025, 27, 12166
DOI: 10.1021/acs.orglett.5c03979

Direct γ-C(sp3)–H Acylation of Amide Derivatives via Cooperative NHC and Photoredox Catalysis

Guihua Nie, Jun Sun, Qingqing Guo, Chengjiang Fang, Qianqian Guo, Renfeng Zhang, Mei Chen and Yuguo Zheng

J. Org. Chem., 2026, 91, 594
DOI: 10.1021/acs.joc.5c02667

Carbene‐Catalyzed Intermolecular Dehydrogenative Coupling of Aldehydes with C(sp3)−H Bonds

Fen Su, Juan Zou, Xiaokang Lv, Fengfei Lu, Yijie Long, Kun Tang, Benpeng Li, Huifang Chai, Xingxing Wu and Yonggui Robin Chi

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202303388

NHC-Catalyzed Access to Benzoxazepinones via Aromatization-Driven Rearrangement

Jun Sun, Guan-Xin Hu, Yu-Lei Yuan, Shi-Chun Jiang, Yong-Gui Liu, Deng-Yue Liu, Jing-Song Lv, Ying-Guo Liu and Bing Zeng

Org. Lett., 2025, 27, 13015
DOI: 10.1021/acs.orglett.5c04114

Synthesis of Sterically Hindered α-Hydroxycarbonyls through Radical–Radical Coupling

Kenji Ota, Kazunori Nagao and Hirohisa Ohmiya

Org. Lett., 2021, 23, 4420
DOI: 10.1021/acs.orglett.1c01358

Visible Light-Mediated Monofluoromethylation/Acylation of Olefins by Dual Organo-Catalysis

Jiuli Xia, Yunliang Guo, Zhiguang Lv, Jiaqiong Sun, Guangfan Zheng and Qian Zhang

Molecules, 2024, 29, 790
DOI: 10.3390/molecules29040790

Bio- and Medicinally Compatible α-Amino-Acid Modification via Merging Photoredox and N-Heterocyclic Carbene Catalysis

Ding Du, Kuili Zhang, Rui Ma, Lei Chen, Jian Gao, Tao Lu, Zhihao Shi and Jie Feng

Org. Lett., 2020, 22, 6370
DOI: 10.1021/acs.orglett.0c02202

Novel 1,3-oxazepine-4,7-dione derivatives with antimicrobial anticancer and corrosion inhibition potential

Rania Faraj, Ahmed Jalil Al-Safi, Mohammed Kassim Al-hussainawy and Abbas K. Abbas

Discov. Chem., 2026, 3
DOI: 10.1007/s44371-025-00462-y

N-Heterocyclic carbene-catalyzed remote C(sp3)–H acylation of amides

Huiwei Xu, Jia-Nan Mo, Wen-Deng Liu and Jiannan Zhao

Tetrahedron Letters, 2023, 121, 154483
DOI: 10.1016/j.tetlet.2023.154483

Synthetic Advantages of Defluorinative C−F Bond Functionalization

Leidy V. Hooker and Jeffrey S. Bandar

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202308880

Enantioselective Synthesis of Axially Chiral Diaryl Ethers via NHC Catalyzed Desymmetrization and Following Resolution

Bang‐An Zhou, Xue‐Ning Li, Chun‐Lin Zhang, Zhi‐Xiang Wang and Song Ye

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202314228

Formation of Breslow Intermediates under Aprotic Conditions: A Computational Study

Gou-Tao Huang, Ming-Hsiu Hsieh and Jen-Shiang K. Yu

J. Org. Chem., 2022, 87, 2501
DOI: 10.1021/acs.joc.1c02408

Cooperative Photoredox and N‐Heterocyclic Carbene Catalyzed Fluoroaroylation for the Synthesis of α‐Trifluoromethyl‐Substituted Ketones

Xiaoye Yu, Anirban Maity and Armido Studer

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202310288

Photoredox cooperative N-heterocyclic carbene/palladium-catalysed alkylacylation of alkenes

You-Feng Han, Ying Huang, Hao Liu, Zhong-Hua Gao, Chun-Lin Zhang and Song Ye

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-33444-0

N -Heterocyclic carbene catalytic 1,2-boron migrative acylation accelerated by photocatalysis

Hua Huang, Zhao-Yuan Yu, Lu-Yao Han, Yi-Qi Wu, Lu Jiang, Qing-Zhu Li, Wei Huang, Bo Han and Jun-Long Li

Sci. Adv., 2024, 10
DOI: 10.1126/sciadv.adn8401

Dipole‐bound states and substituent effects of Breslow intermediates in the enolate form

Ming‐Hsiu Hsieh, Gou‐Tao Huang and Jen‐Shiang K. Yu

J Chinese Chemical Soc, 2021, 68, 2060
DOI: 10.1002/jccs.202100310

How To Enhance the Efficiency of Breslow Intermediates for SET Catalysis

Florian F. Mulks, Mohand Melaimi, Xiaoyu Yan, Mu-Hyun Baik and Guy Bertrand

J. Org. Chem., 2023, 88, 2535
DOI: 10.1021/acs.joc.2c02978

Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals

Xiaoqun Yang, Hongling Wang, Zhichao Jin and Yonggui Robin Chi

Green Synthesis and Catalysis, 2021, 2, 295
DOI: 10.1016/j.gresc.2021.05.002

Remote Electronic Tuning for High-performance N-Heterocyclic Carbene Catalysis

Tsubasa Inokuma and Ken-ichi Yamada

J. Synth. Org. Chem. Jpn., 2024, 82, 222
DOI: 10.5059/yukigoseikyokaishi.82.222

Construction of highly congested quaternary carbon centers by NHC catalysis through dearomatization

Lixia Liu, Cong-Ying Zhou and Chengming Wang

Green Synthesis and Catalysis, 2023, 4, 263
DOI: 10.1016/j.gresc.2022.05.010

Combined Photoredox and Carbene Catalysis for the Synthesis of γ‐Aryloxy Ketones

Pengzhi Wang, Keegan P. Fitzpatrick and Karl A. Scheidt

Adv Synth Catal, 2022, 364, 518
DOI: 10.1002/adsc.202101354

Tunable Thiazolium Carbenes for Enantioselective Radical Three-Component Dicarbofunctionalizations

Sripati Jana and Nicolai Cramer

J. Am. Chem. Soc., 2024, 146, 35199
DOI: 10.1021/jacs.4c11947

Efficient Synthesis of Biaryl‐Bridged Seven‐Membered Lactones via N‐Heterocyclic Carbene Catalyzed Dynamic Kinetic Resolution

Huan Gong, Hongzhi Zhuang, Yang Xiao, Yao Chen, Xiaoqing Lai, Zhuofeng Deng, Jianing An, Yiqun Li, Jianfeng Xu and Xingkuan Chen

Chin. J. Chem., 2025, 43, 2318
DOI: 10.1002/cjoc.70120

CF2Br2 as a Source for Difluoroolefination of 1,3-Enynes via N-Heterocyclic Carbene Catalysis

Lei Chen, Jingyi Wang, Chen Lin, Yiwei Zhu and Ding Du

Org. Lett., 2022, 24, 7047
DOI: 10.1021/acs.orglett.2c03007

Carbene‐Catalyzed Intermolecular Dehydrogenative Coupling of Aldehydes with C(sp3)−H Bonds

Fen Su, Juan Zou, Xiaokang Lv, Fengfei Lu, Yijie Long, Kun Tang, Benpeng Li, Huifang Chai, Xingxing Wu and Yonggui Robin Chi

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202303388

Thiamine (Vitamin B1) Promoted Organic Transformations: A Recent Updates

Ranjay Shaw and Prasoon Prakash

Chemistry An Asian Journal, 2024, 19
DOI: 10.1002/asia.202400841

Radical N-heterocyclic carbene catalysis for β-ketocarbonyl synthesis

Takuya Ishii, Kazunori Nagao and Hirohisa Ohmiya

Tetrahedron, 2021, 91, 132212
DOI: 10.1016/j.tet.2021.132212

NHC-mediated photocatalytic para-selective C–H acylation of aryl alcohols: regioselectivity control via remote radical spiro cyclization

Tinglei Zhang, Lala Wang, Xiaolin Peng, Tianhui Liao, Dongmei Chen, Ting Tu, Donghan Liu, Ziye Cheng, Shiqing Huang, Shi-Chao Ren, Xinglong Zhang and Yonggui Robin Chi

Sci. China Chem., 2025, 68, 3611
DOI: 10.1007/s11426-024-2481-5

Improved Protocols for the Synthesis of Precursors of Thiazol-2-ylidene N-Heterocyclic Carbenes

Ludivine Delfau, Jacques Pecaut, Eder Tomás-Mendivil and David Martin

Synlett, 2024, 35, 2097
DOI: 10.1055/a-2284-4798

Divergent Construction of Heterocycles by SOMOphilic Isocyanide Insertion under N-Heterocyclic Carbene Catalysis

Qianrong Li, Cong-Ying Zhou and Chengming Wang

Org. Lett., 2022, 24, 7654
DOI: 10.1021/acs.orglett.2c03148

On the Redox Properties of the Dimers of Thiazol-2-ylidenes That Are Relevant for Radical Catalysis

Ludivine Delfau, Nadhrata Assani, Samantha Nichilo, Jacques Pecaut, Christian Philouze, Julie Broggi, David Martin and Eder Tomás-Mendivil

ACS Org. Inorg. Au, 2023, 3, 136
DOI: 10.1021/acsorginorgau.3c00008

Photoredox N-heterocyclic carbene catalysis via radicals

Zi-Hao Xia, Zhong-Hua Gao and Song Ye

Sci. China Chem., 2026
DOI: 10.1007/s11426-025-3107-4

Alkyl and Aryl Thioester Synthesis via N-Heterocyclic Carbene-Catalyzed α-Thio Aldehyde Rearrangement

Tatsuya Fujiwara, Tsubasa Inokuma and Ken-ichi Yamada

Org. Lett., 2026, 28, 136
DOI: 10.1021/acs.orglett.5c04522

Dual N-Heterocyclic Carbene/Photoredox-Catalyzed Coupling of Acyl Fluorides and Alkyl Silanes

Michael Jakob, Luca Steiner, Marius Göbel, Jan P. Götze and Matthew N. Hopkinson

ACS Catal., 2024, 14, 17642
DOI: 10.1021/acscatal.4c03103

N-Heterocyclic carbene-derived second-period main-group radicals: Synthesis, fundamentals, and applications

Solhye Choe, Chaerin Lim, Sunghoon Kang and Eunsung Lee

Chem, 2025, 11, 102714
DOI: 10.1016/j.chempr.2025.102714

Mechanistic Investigation on an NHC‐Catalyzed [3 + 3] Annulation of 2‐Bromoenals with β‐Oxodithioester: Mechanism, Origins of Stereoselectivity

Sai‐Bo Cao and Yang Wang

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.70143

Investigating the Catalytic Efficiency of Supported NHC‐Ag(I) Complexes in the Borono‐Minisci Reaction

Giada Moroni, Elena Bombonato, Samuele Bonafè, Alessandro Di Michele, Sara Presenti, Sara Guariento, Massimo Marcaccio, Roccaldo Sardella, Paolo Ronchi and Antimo Gioiello

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202301654

N-Heterocyclic Carbene-Catalyzed (3 + 3) Annulation for the Diastereo- and Atroposelective Synthesis of N–N Axially Chiral Quino(xa)linones

Sowmya Shree Ranganathappa, Krishnendhu Karickal Radhakrishnan, Fathima Dinsha Paravakkal and Akkattu T. Biju

ACS Sustainable Chem. Eng., 2026, 14, 5238
DOI: 10.1021/acssuschemeng.6c00722

Carbene‐Catalyzed Activation of Remote Nitrogen Atoms of (Benz)imidazole‐Derived Aldimines for Enantioselective Synthesis of Heterocycles

Xing Yang, Yongtao Xie, Jun Xu, Shichao Ren, Bivas Mondal, Liejin Zhou, Weiyi Tian, Xinglong Zhang, Lin Hao, Zhichao Jin and Yonggui Robin Chi

Angew Chem Int Ed, 2021, 60, 7906
DOI: 10.1002/anie.202016506

Redox-Paired Reductive Heck Reaction and Oxidative Esterification Catalyzed by Mesoionic Carbenes

Benkai Huang, Zengyu Zhang, Jie Jiao, Wei Liu and Xiaoyu Yan

Org. Lett., 2024, 26, 7419
DOI: 10.1021/acs.orglett.4c02762

Acyldifluoromethylation Enabled by NHC-Photoredox Cocatalysis

Bei Zhang and Jian Wang

Org. Lett., 2022, 24, 3721
DOI: 10.1021/acs.orglett.2c01375

Construction of N-Polyheterocycles by N-Heterocyclic Carbene Catalysis via a Regioselective Intramolecular Radical Addition/Cyclization Cascade

Qijing Zhang, Hao Lei, Cong-Ying Zhou and Chengming Wang

Org. Lett., 2022, 24, 4615
DOI: 10.1021/acs.orglett.2c01729

N-Heterocyclic Carbene/Magnesium Cocatalyzed Radical Relay Assembly of Aliphatic Keto Nitriles

Lei Chen, Shiyi Jin, Jian Gao, Tongtong Liu, Yuebo Shao, Jie Feng, Kangyi Wang, Tao Lu and Ding Du

Org. Lett., 2021, 23, 394
DOI: 10.1021/acs.orglett.0c03883

Mechanism and Diastereoselectivity of the Photo‐/NHC Cocatalyzed Fluoroacylation of Benzofurans: A Theoretical View

Zehua Li, Jiying Liu, Jiabin Liu, Panpan Bao, Huixian Jing, Hui Chen and Wenjing Zhang

J of Physical Organic Chem, 2025, 38
DOI: 10.1002/poc.70007

Carbene-Catalyzed Intramolecular Cyclization to Access Inherently Chiral Saddle-Shaped Lactones: Achiral Bases Alternate Product Chirality

Liwen Wei, Yuhang Chen, Qinglong Zhou, Zhikang Wei, Ting Tu, Shichao Ren, Yonggui Robin Chi, Xinglong Zhang and Xing Yang

J. Am. Chem. Soc., 2025, 147, 30747
DOI: 10.1021/jacs.5c05380

NHC‐Catalyzed Radical Cross‐Claisen Condensation for Diverse β‐Keto Ester Synthesis

Xiangyu Zhuang, Hao Li and Hongyu Wang

Chin. J. Chem., 2025, 43, 2997
DOI: 10.1002/cjoc.70214

N-Heterocyclic Carbene-Catalyzed Remote Enantioselective C–C Bond Formation via 1,6-Addition with Formyl Enynes

Xiaolin Peng, Yixian Huang, Wei Wang, Shiguang Li, Ge-fei Hao, Shichao Ren and Yonggui Robin Chi

ACS Catal., 2024, 14, 2127
DOI: 10.1021/acscatal.3c04733

Photocatalytic Radical Umpolung for Strain‐Release Difunctionalization of (Aza)bicyclo[1.1.0]butanes

Chang‐Yin Tan, Hyewon Ju, Jinwook Jeong, Jaehun Kim and Sungwoo Hong

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202517231

Stereoselective Access to Silicon-Stereogenic Silacycles via the Carbene-Catalyzed Desymmetric Benzoin Reaction of Siladials

Hao Liu, Pengyu He, Xuanlong Liao, Yipeng Zhou, Xingkuan Chen, Wenpiao Ou, Zhenhong Wu, Cong Luo, Limin Yang and Jianfeng Xu

ACS Catal., 2022, 12, 9864
DOI: 10.1021/acscatal.2c02805

N‐Heterocyclic Carbene‐Catalyzed Activation of 3‐Membered Rings: Cyclopropanes, Epoxides, Azirines and Aziridines

Xiaoqun Yang, Yi Zhang, Tingting Li and Zhichao Jin

Adv Synth Catal, 2023, 365, 1756
DOI: 10.1002/adsc.202300095

Generation and Radical–Radical Cross-Coupling of Alkenyloxy Radical

Yunquan Man and Bo Xu

Org. Lett., 2024, 26, 2456
DOI: 10.1021/acs.orglett.4c00627

Photoinduced Electron Transfer from Xanthates to Acyl Azoliums: Divergent Ketone Synthesis via N‐Heterocyclic Carbene Catalysis

Chang‐Yin Tan, Minseok Kim and Sungwoo Hong

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202306191

Acetal Radicals: Synthetic Access and Applications

Kyra L. Samony and Daniel K. Kim

ChemCatChem, 2023, 15
DOI: 10.1002/cctc.202301091

Research Progress on N-Heterocyclic Carbene Catalyzed Reactions for Synthesizing Ketones through Radical Mechanism

Dan-Hong Wan and Hai-Bin Yang

Synthesis, 2022, 54, 3307
DOI: 10.1055/a-1822-4690

NHC‐Organocatalyzed Multicomponent Fluorination and Fluoroalkylation for Access to Fluorine‐Containing Compounds

Jie Lv, Ziliang Yuan, Xinyan Yang, Xuning Qiu, Yimeng Yang and Yanrong Ren

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202401473

N-heterocyclic carbene-catalyzed atroposelective synthesis of N-Aryl phthalimides and maleimides via activation of carboxylic acids

Soumen Barik, Sowmya Shree Ranganathappa and Akkattu T. Biju

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-49799-5

Nature-Inspired Radical Pyridoxal-Mediated C–C Bond Formation

Ye Wang, Soumik Das, Kareem Aboulhosn, Sarah E. Champagne, Philipp M. Gemmel, Kevin C. Skinner, Stephen W. Ragsdale, Paul M. Zimmerman and Alison R. H. Narayan

J. Am. Chem. Soc., 2024, 146, 23321
DOI: 10.1021/jacs.4c05997

Mechanisms and Origins of Regio- and Stereoselectivities in NHC-Catalyzed [3 + 3] Annulation of α-Bromoenals and 5-Aminoisoxazoles: A DFT Study

Mingchao Zhang, Zhiqiang Zhang and Yan Li

J. Org. Chem., 2024, 89, 10748
DOI: 10.1021/acs.joc.4c00980

Transition Metal Complexes Supported by N‐Heterocyclic Carbene‐Based Pincer Platforms: Synthesis, Reactivity and Applications

Yidan Wang, Bo Zhang and Shuai Guo

Eur J Inorg Chem, 2021, 2021, 188
DOI: 10.1002/ejic.202000911

Modular Access to Ketones via Cooperative NHC/Pd-Catalyzed C–H Alkylation of Aldehydes with Alkyl Bromides

Ying Huang, You-Feng Han, Chun-Lin Zhang and Song Ye

ACS Catal., 2023, 13, 11033
DOI: 10.1021/acscatal.3c02844

Asymmetric Aminative Dearomatization of 2-Naphthols via Non-covalent N-Heterocyclic Carbene Catalysis

Ujjwal Maji, Bhaskar Deb Mondal and Joyram Guin

Org. Lett., 2023, 25, 2323
DOI: 10.1021/acs.orglett.3c00700

Organic Photoredox-Catalyzed Silyl Radical Generation from Silylboronate

Naho Takemura, Yuto Sumida and Hirohisa Ohmiya

ACS Catal., 2022, 12, 7804
DOI: 10.1021/acscatal.2c01964

An overview on generation and general properties of N-heterocyclic carbenes: Applications of 1,2,4-triazolium carbenes as metal free organocatalysts

Raphael Silva Moratório de Moraes, Maria Tereza Miranda Martins, Gabriel Tavares de Almeida Pinto, Searitha Couto Rodrigues, Patrick Antunes do Nascimento, Camille Cardoso Cruz, Karina D'Oliveira Góes and Anna Claudia Cunha

Arabian Journal of Chemistry, 2024, 17, 105527
DOI: 10.1016/j.arabjc.2023.105527

Visible-Light-Driven Bisfunctionalization of Unactivated Olefins via the Merger of Proton-Coupled Electron Transfer and Carbene Catalysis

Bei Zhang, Jian-Qing Qi, Yuhan Liu, Zhipeng Li and Jian Wang

Org. Lett., 2022, 24, 279
DOI: 10.1021/acs.orglett.1c03941

N-Heterocyclic Carbene/Organic Photoredox-Cocatalyzed Acyl Azolation of Alkenes with Acyl Azoles

Kanata Togishi, Yamato Goto, Sho Murakami and Hirohisa Ohmiya

Org. Lett., 2025, 27, 5760
DOI: 10.1021/acs.orglett.5c01533

N-heterocyclic carbene-catalyzed nucleophilic aromatic substitution reaction of polyfluoroarenes

Lishuai Lu, Dengyu Yin, Xiao-Xuan Li, Yandong Dou, Yanwu Zhu and Shilu Fan

Synthetic Communications, 2024, 54, 1551
DOI: 10.1080/00397911.2024.2395993

Enantioselective carbene-catalyzed tandem reaction for the efficient synthesis of pyrroloindolone and pyrrolidine derivatives with four consecutive stereocenters

Zhiying Li, Yao Chen, Xinyi Xu, Ziyi Xiao, Jiaqing Peng, Jianing An, Jianfeng Xu and Xingkuan Chen

Journal of Catalysis, 2025, 450, 116279
DOI: 10.1016/j.jcat.2025.116279

Mechanistic Investigation on NHC‐Catalyzed Switchable Annulation Reactions: Polarity Controlled Chemoselective Pathways

Linjie Zheng and Yang Wang

Asian J Org Chem, 2026, 15
DOI: 10.1002/ajoc.70347

NHC-Catalyzed Synthesis of α-Sulfonyl Ketones via Radical-Mediated Sulfonyl Methylation of Aldehydes

Chaolei Liu, Zheng Liang, Ayisenbati Jialingbieke, Jian Gao and Ding Du

Org. Lett., 2023, 25, 2657
DOI: 10.1021/acs.orglett.3c00734

N-heterocyclic carbene-catalyzed radical reactions

Kun-Quan Chen, He Sheng, Qiang Liu, Pan-Lin Shao and Xiang-Yu Chen

Sci. China Chem., 2021, 64, 7
DOI: 10.1007/s11426-020-9851-8

Visible-light-driven radical NHC Organocatalysis for Phosphonylacylation of Styrenes

Wei Li, Xingxing Wu and Benpeng Li

Tetrahedron Letters, 2026, 179, 156011
DOI: 10.1016/j.tetlet.2026.156011

Radikalische C─H‐Aroylierung von Allenen mittels kooperativer Photoredox‐ und N‐heterozyklischer Carben‐Katalyse

Shyam Kumar Banjare, Lena Lezius and Armido Studer

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202511689

Stereoselective Radical Acylfluoroalkylation of Bicyclobutanes via N‐Heterocyclic Carbene Catalysis

Chuyu Xiao, Jing‐Ran Shan, Wen‐Deng Liu, Xingyuan Gao, Jingwei Dai, Zuwei Wang, Wentao Wang, K. N. Houk and Jiannan Zhao

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202416781

Catalytic Activation of Acceptor–Acceptor Bicyclobutanes Enabled by Lewis Base Catalysis

Jin‐Lan Zhou, Xuan Zhan, Heng‐Xian He, Youzhi Xu, Quanxin Peng, Genping Huang and Jian‐Jun Feng

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202507590

Mesoionic Carbene‐Catalyzed Formyl Alkylation of Aldehydes

Chang Liu, Zengyu Zhang, Liang‐Liang Zhao, Guy Bertrand and Xiaoyu Yan

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202303478

Harnessing the potential of acyl triazoles in bifunctional cobalt-catalyzed radical cross-coupling reactions

Chang-Yin Tan and Sungwoo Hong

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-51376-9

Carbene‐Catalyzed Activation of Remote Nitrogen Atoms of (Benz)imidazole‐Derived Aldimines for Enantioselective Synthesis of Heterocycles

Xing Yang, Yongtao Xie, Jun Xu, Shichao Ren, Bivas Mondal, Liejin Zhou, Weiyi Tian, Xinglong Zhang, Lin Hao, Zhichao Jin and Yonggui Robin Chi

Angewandte Chemie, 2021, 133, 7985
DOI: 10.1002/ange.202016506

Organocatalytic activation of cyclopropanes in asymmetric synthesis

Efraím Reyes, Uxue Uria, Liher Prieto, Luisa Carrillo and Jose L. Vicario

Tetrahedron Chem, 2023, 7, 100041
DOI: 10.1016/j.tchem.2023.100041

Diastereoselective congested β-amido ketone synthesis via NHC-catalyzed radical-radical coupling

Yukiya Sato, Yusuke Miyamoto, Takanori Matsui, Yuto Sumida and Hirohisa Ohmiya

Chem Catalysis, 2023, 3, 100736
DOI: 10.1016/j.checat.2023.100736

Oxidative Radical NHC Catalysis: Divergent Difunctionalization of Olefins through Intermolecular Hydrogen Atom Transfer

Qing‐Zhu Li, Yan‐Qing Liu, Xin‐Xin Kou, Wen‐Lin Zou, Ting Qi, Peng Xiang, Jin‐Dun Xing, Xiang Zhang and Jun‐Long Li

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202207824

Cooperative N-heterocyclic carbenes and photocatalysis for the three-component alkylacylation of alkenes: divergent ketone synthesis

Kui Tian, Fengrui Xiang, Jin-Long Huang, Yao-Wen Song, Minyan Wang, Chun-Jiang Wang and Xiu-Qin Dong

Sci. China Chem., 2025, 68, 5776
DOI: 10.1007/s11426-025-2680-2

Asymmetric synthesis of atropisomers enabled by N-heterocyclic carbene catalysis

Jie Feng and Ding Du

Tetrahedron, 2021, 100, 132456
DOI: 10.1016/j.tet.2021.132456

Remote C(sp3)−H Acylation of Amides and Cascade Cyclization via N‐Heterocyclic Carbene Organocatalysis

Qing‐Zhu Li, Rong Zeng, Yang Fan, Yan‐Qing Liu, Ting Qi, Xiang Zhang and Jun‐Long Li

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202116629

Norrish type II reactions of acyl azolium salts

Andreas Mavroskoufis, Arielle Rieck and Matthew N. Hopkinson

Tetrahedron, 2021, 100, 132497
DOI: 10.1016/j.tet.2021.132497

Dual NHC/Organophotoredox-Catalyzed Radical Phosphinoylacylation of Alkenes with Acyl Fluorides and H-Phosphine Oxides

Rongzao Yang, Jiabin Liao, Hui Xi, Miao-Miao Li and Wei Ding

J. Org. Chem., 2025, 90, 8767
DOI: 10.1021/acs.joc.5c00988

Construction of alkenyl-isoquinolinones through NHC-catalyzed remote C(sp3)–H acylation and cascade cyclization of benzamides and enals

Rong Zeng, Chuan Xie, Jin-Dun Xing, Hai-Yu Dai, Mei-Hao He, Peng-Shuai Xu, Qi-Chun Yang, Bo Han and Jun-Long Li

Tetrahedron, 2023, 132, 133239
DOI: 10.1016/j.tet.2022.133239

Atroposelective Access to 1,3‐Oxazepine‐Containing Bridged Biaryls via Carbene‐Catalyzed Desymmetrization of Imines

Xing Yang, Liwen Wei, Yuelin Wu, Liejin Zhou, Xinglong Zhang and Yonggui Robin Chi

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202211977

Alkene Diversification through a Molecular Recasting Strategy Enabled by N -Heterocyclic Carbene and Photoredox Dual Catalysis

Qing-Zhu Li, Mei-Hao He, Peng-Tao Wang, Dong-Yang Xiang, Long-Hai Hong, Rong Zeng and Jun-Long Li

Research, 2025, 8
DOI: 10.34133/research.1010

Synthesis, crystal structures, DFT calculations, and catalytic application in hydrosilylation of acetophenone derivatives with triethylsilane of novel rhoduim-N-heterocyclic carbene (NHCs) complex

Sabri Hassen, Mohamed Oussama Zouaghi, Ichraf Slimani, Youssef Arfaoui, Namık Özdemir, Ismail Özdemir, Nevin Gürbüz, Lamjed Mansour, Rafik Gatri and Naceur Hamdi

Journal of Molecular Structure, 2022, 1265, 133397
DOI: 10.1016/j.molstruc.2022.133397

N-Heterocyclic-Carbene-Catalyzed C–H Acylation via Radical Relay

Yunquan Man, Shiwen Liu, Bo Xu and Xiaojun Zeng

Org. Lett., 2022, 24, 944
DOI: 10.1021/acs.orglett.1c04317

Distal difunctionalization of aldehydes via the triplet state of Breslow intermediates

Hongling Wang, Xingxing Wu and Yonggui Robin Chi

Chem Catalysis, 2022, 2, 3275
DOI: 10.1016/j.checat.2022.11.002

Organocatalytic C−H Functionalization of Simple Alkanes

Fen Su, Fengfei Lu, Kun Tang, Xiaokang Lv, Zhongfu Luo, Fengrui Che, Hongyan Long, Xingxing Wu and Yonggui Robin Chi

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202310072

Dark and Light Reactions of Carbenes─Merging Carbene Transfer Reactions with N-Heterocyclic Carbene Catalysis for the Synthesis of Hydroxamic Acid Esters

Bao-Gui Cai, Qian Li, Claire Empel, Lei Li, Rene M. Koenigs and Jun Xuan

ACS Catal., 2022, 12, 11129
DOI: 10.1021/acscatal.2c02875

Recent advances in N-heterocyclic carbene-catalyzed radical reactions

Lei Dai and Song Ye

Chinese Chemical Letters, 2021, 32, 660
DOI: 10.1016/j.cclet.2020.08.027

Critical Assessment of the Reducing Ability of Breslow‐type Derivatives and Implications for Carbene‐Catalyzed Radical Reactions**

Ludivine Delfau, Samantha Nichilo, Florian Molton, Julie Broggi, Eder Tomás‐Mendivil and David Martin

Angewandte Chemie, 2021, 133, 26987
DOI: 10.1002/ange.202111988

Thiazolium Salts: From Thiamine to Cutting‐Edge Organocatalysts

Ilan Garcin, Ludovic Maillard, Jean‐Marc Campagne and Renata Marcia de Figueiredo

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.70087

Cooperative Photoredox and N‐Heterocyclic Carbene Catalyzed Fluoroaroylation for the Synthesis of α‐Trifluoromethyl‐Substituted Ketones

Xiaoye Yu, Anirban Maity and Armido Studer

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202310288

Catalytic, Metal-Free Amide Synthesis from Aldehydes and Imines Enabled by a Dual-Catalyzed Umpolung Strategy under Redox-Neutral Conditions

Ming-Shang Liu and Wei Shu

ACS Catal., 2020, 10, 12960
DOI: 10.1021/acscatal.0c04070

Atroposelective Synthesis of Axially Chiral 4-Aryl α-Carbolines via N-Heterocyclic Carbene Catalysis

Rui Ma, Xiaoxue Wang, Qiaoyu Zhang, Lei Chen, Jian Gao, Jie Feng, Donghui Wei and Ding Du

Org. Lett., 2021, 23, 4267
DOI: 10.1021/acs.orglett.1c01221

NHC‐Catalyzed Radical Tandem Cyclization/Coupling Reaction for the Synthesis of 2‐Pyrrolidinone Derivatives

Nengneng Zhou, Lei Wang, Fangli Zhao, Xiang Gao, Xiaowei Zhao and Man Zhang

Asian J Org Chem, 2023, 12
DOI: 10.1002/ajoc.202300334

Enantioselective Synthesis of Highly Substituted Fluoroalkylated Benzopyranones and 3-Coumaranones via N-Heterocyclic Carbene-Catalyzed Intramolecular Annulations

Izabela Barańska, Katarzyna Rafińska and Zbigniew Rafiński

J. Org. Chem., 2023, 88, 14339
DOI: 10.1021/acs.joc.3c01099

Atroposelective Synthesis of Axially Chiral Diaryl Ethers by N-Heterocyclic-Carbene-Catalyzed Sequentially Desymmetric/Kinetic Resolution Process

Libo Li, Wenqing Ti, Tianshu Miao, Jiao Ma, Aijun Lin, Qian Chu and Shang Gao

J. Org. Chem., 2024, 89, 4067
DOI: 10.1021/acs.joc.3c02912

Synthesis of γ-Oxo-phosphonates via N-Heterocyclic Carbene-Catalyzed Acylphosphorylation of Alkenes

Jia-Nan Mo, Shengbin Sun, Huiwei Xu, Hanyu Shu and Jiannan Zhao

Org. Lett., 2024, 26, 2197
DOI: 10.1021/acs.orglett.4c00234

N-Heterocyclic carbene-catalyzed enantioselective synthesis of planar-chiral cyclophanes via dynamic kinetic resolution

Jiayan Li, Ziyang Dong, Yang Chen, Zhanhui Yang, Xinen Yan, Meng Wang, Chenyang Li and Changgui Zhao

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-46376-8

Combined Photoredox and Carbene Catalysis for the Synthesis of α-Amino Ketones from Carboxylic Acids

Xiaochen Wang, Binbing Zhu, Yuxiu Liu and Qingmin Wang

ACS Catal., 2022, 12, 2522
DOI: 10.1021/acscatal.1c05815

Direct Synthesis of Dialkyl Ketones from Aliphatic Aldehydes through Radical N-Heterocyclic Carbene Catalysis

Yuki Kakeno, Mayu Kusakabe, Kazunori Nagao and Hirohisa Ohmiya

ACS Catal., 2020, 10, 8524
DOI: 10.1021/acscatal.0c02849

The triplet state of deprotonated mesoionic carbene Breslow intermediates is thermally accessible: Distal difunctionalization of aldehydes

Zengyu Zhang, Shiqing Huang, Chen-Yuan Li, Liang-Liang Zhao, Wei Liu, Mohand Melaimi, Guy Bertrand and Xiaoyu Yan

Chem Catalysis, 2022, 2, 3517
DOI: 10.1016/j.checat.2022.09.047

Unnatural Thiamine Radical Enzymes for Photobiocatalytic Asymmetric Alkylation of Benzaldehydes and α-Ketoacids

Xin Liu, Sheng Xu, Heyu Chen and Yang Yang

ACS Catal., 2024, 14, 9144
DOI: 10.1021/acscatal.4c02752

Direct Acylation of Unactivated Alkyl Halides with Aldehydes through N‐Heterocyclic Carbene Organocatalysis

Qing‐Zhu Li, Rong Zeng, Peng‐Shuai Xu, Xin‐Hang Jin, Chuan Xie, Qi‐Chun Yang, Xiang Zhang and Jun‐Long Li

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202309572

Photochemical Decarboxylative C(sp3)–X Coupling Facilitated by Weak Interaction of N-Heterocyclic Carbene

Kun-Quan Chen, Zhi-Xiang Wang and Xiang-Yu Chen

Org. Lett., 2020, 22, 8059
DOI: 10.1021/acs.orglett.0c03006

A Benzannulation Strategy for Rapid Access to Quinazoline-2,4-diones via Oxidative N-Heterocyclic Carbene Catalysis

Arghya Ghosh, Sayan Shee and Akkattu T. Biju

Org. Lett., 2022, 24, 2772
DOI: 10.1021/acs.orglett.2c00954

Use of Aliphatic Carboxylic Acid Derivatives for NHC/Photoredox-Catalyzed meta-Selective Acylation of Electron-Rich Arenes

Yamato Goto, Sho Murakami, Yuto Sumida and Hirohisa Ohmiya

Synthesis, 2024, 56, 3327
DOI: 10.1055/a-2281-2975

Radical Relay Trichloromethylacylation of Alkenes through N-Heterocyclic Carbene Catalysis

Mayu Kusakabe, Kazunori Nagao and Hirohisa Ohmiya

Org. Lett., 2021, 23, 7242
DOI: 10.1021/acs.orglett.1c02639

N‐Heterocyclic Carbenes (NHCs)‐Catalyzed Coupling Reactions of Aldehydes and Organic Halides

Fan Gao, Zengyu Zhang and Xiaoyu Yan

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202301331

NHC-Catalyzed Three-Component Hydroalkylation Reactions of [60]Fullerene: An Umpolung Approach to Diverse Monoalkylated Hydrofullerenes

Tong-Xin Liu, Xue Zhu, Shilu Xia, Xin Wang, Pengling Zhang and Guisheng Zhang

Org. Lett., 2022, 24, 3691
DOI: 10.1021/acs.orglett.2c01301

Cross‐Coupling Reaction of Alkyl Halides with Aldehydes through NHC Catalysis

Zhuo‐Zhuo Zhang, Rong Zeng, Yan‐Qing Liu and Jun‐Long Li

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202400063

1,2-Aminoalkylacylation of styrenes by cooperative NHC/photoredox dual catalysis

Lili Wu and Chengming Wang

Synthetic Communications, 2025, 55, 618
DOI: 10.1080/00397911.2025.2486106

The Chemistry of Vanadium bis‐Phenolate NHC Complexes in Three Oxidation States

Florian R. Neururer, Daniel Leitner, Shenyu Liu, Klaus Wurst, Holger Kopacka, Michael Seidl and Stephan Hohloch

Eur J Inorg Chem, 2023, 26
DOI: 10.1002/ejic.202300180

Stereoselective Radical Acylfluoroalkylation of Bicyclobutanes via N‐Heterocyclic Carbene Catalysis

Chuyu Xiao, Jing‐Ran Shan, Wen‐Deng Liu, Xingyuan Gao, Jingwei Dai, Zuwei Wang, Wentao Wang, K. N. Houk and Jiannan Zhao

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202416781

N-Heterocyclic Carbene-Photocatalyzed Tricomponent Regioselective 1,2-Diacylation of Alkenes Illuminates the Mechanistic Details of the Electron Donor–Acceptor Complex-Mediated Radical Relay Processes

Shengfei Jin, Xianwei Sui, Graham C. Haug, Viet D. Nguyen, Hang T. Dang, Hadi D. Arman and Oleg V. Larionov

ACS Catal., 2022, 12, 285
DOI: 10.1021/acscatal.1c04594

Asymmetric Intermolecular Conjugate Addition of 3-Substituted 2-Benzofuranones to Maleimides via Noncovalent NHC Catalysis

Bhaskar Deb Mondal, Sadhan Gorai and Joyram Guin

Synlett, 2024, 35, 2453
DOI: 10.1055/a-2403-2383

Redox-Neutral Generation of Iminyl Radicals by N-Heterocyclic Carbene Catalysis: Rapid Access to Phenanthridines from Vinyl Azides

Lixia Liu, Qijing Zhang and Chengming Wang

Org. Lett., 2022, 24, 5913
DOI: 10.1021/acs.orglett.2c02118

N‐Heterocyclic carbene‐catalyzed Atroposelective Annulation for Access to Pyrrolo[3,4‐b]pyridines Derivatives with C−N Axial Chirality

Yanting Li, Xiao‐Yong Duan, Yamei Wei, Jiahan Li, Xiaojie Ren and Jing Qi

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202200383

Light-Driven N-Heterocyclic Carbene-Catalyzed Multi-Component Reaction for the Synthesis of β-Amino Ketones

Chengcheng Shi, Nan Zhong, Lin Guo, Jiawen Yin, Chao Yang and Wujiong Xia

Org. Lett., 2024, 26, 8848
DOI: 10.1021/acs.orglett.4c03288

Atroposelective Construction of C─B Axial Chirality via N‐Heterocyclic Carbene‐Catalyzed Dynamic Kinetic Resolution

Ying Huang, Xue‐Ning Li, Xin‐Han Wang, Zhi‐Xiang Wang, Song Ye and Chun‐Lin Zhang

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202501991

Recent Advances in NHC‐Catalyzed Chemoselective Activation of Carbonyl Compounds

Yixian Huang, Xiaolin Peng and Tingting Li

Chemistry An Asian Journal, 2024, 19
DOI: 10.1002/asia.202400097

NHC Catalyzed β-Carbon functionalization of carboxylic esters towards formation of δ-Lactams: A mechanistic study

Yan Li, Zhiyi Song and Zhiqiang Zhang

Molecular Catalysis, 2022, 524, 112311
DOI: 10.1016/j.mcat.2022.112311

Carbene‐Catalyzed Asymmetric Construction of Atropisomers

Runjiang Song, Yongtao Xie, Zhichao Jin and Yonggui Robin Chi

Angewandte Chemie, 2021, 133, 26230
DOI: 10.1002/ange.202108630

Assembly of versatile fluorine-containing structures via N-heterocyclic carbene organocatalysis

Bei Zhang and Jian Wang

Sci. China Chem., 2022, 65, 1691
DOI: 10.1007/s11426-022-1291-2

Enantioselective Relay Coupling of Perfluoroalkyl and Vinylogous Ketyl Radicals

Yuxin Zhao, Yichi Zhang and Yong Huang

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202409566