Bidirectional noninnocence of hinge-like deprotonated bis-lawsone on selective ruthenium platform: a function of varying ancillary ligands

Yogita Arya, Sudip Kumar Bera, José Luis Priego, Reyes Jiménez-Aparicio and Goutam Kumar Lahiri

Dalton Trans., 2022, 51, 10441
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meso-Tetra-(4-pyridyl)porphyrin/palladium(ii) complexes as anticancer agents

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Dalton Trans., 2021, 50, 16254
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Recent trends in the design and delivery strategies of ruthenium complexes for breast cancer therapy

Utpal Das, Uttara Basu and Priyankar Paira

Dalton Trans., 2024, 53, 15113
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Ru(ii)/diclofenac-based complexes: DNA, BSA interaction and their anticancer evaluation against lung and breast tumor cells

Katia M. Oliveira, João Honorato, Guilherme R. Gonçalves, Marcia R. Cominetti, Alzir A. Batista and Rodrigo S. Correa

Dalton Trans., 2020, 49, 12643
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Non-mutagenic Ru(ii)–phosphine-based complexes induce mitochondria-mediated apoptosis in breast cancer cells: from 2D to 3D investigations

Marcos V. Palmeira-Mello, Tamara Teixeira, Analu R. Costa, Aline Maria Machado, Rone A. De Grandis, Leticia P. de Oliveira, Carlos A. F. Moraes, João H. de Araujo-Neto, Victor M. Deflon, Adriano D. Andricopulo, Javier Ellena, Heloisa S. Selistre-de-Araújo, Fillipe V. Rocha and Alzir A. Batista

Inorg. Chem. Front., 2025, 12, 4812
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High cytotoxic and apoptotic effects of platinum(ii) complexes bearing the 4-acridinol ligand

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New J. Chem., 2020, 44, 19885
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Naphthoyl benzhydrazine–decorated binuclear arene Ru(ii) complexes as anticancer agents targeting human breast cancer cells

Arunachalam Abirami, Umapathy Devan, Rengan Ramesh, Arockiam Antony Joseph Velanganni and Jan Grzegorz Małecki

Dalton Trans., 2023, 52, 16376
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Exploring the potential of ruthenium(ii)–phosphine–mercapto complexes as new anticancer agents

Marcos V. Palmeira-Mello, Analu R. Costa, Leticia P. de Oliveira, Olivier Blacque, Gilles Gasser and Alzir A. Batista

Dalton Trans., 2024, 53, 10947
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Ruthenium(II)-mercapto complexes induce cell damage via apoptosis pathway on ovarian cancer cells

Marcos V. Palmeira-Mello, Tamara Teixeira, Matheus Reis Santos de Melo, Heloiza Diniz Nicolella, Jocely L. Dutra, Marcia R. Cominetti, Fillipe Vieira Rocha, Denise Crispim Tavares and Alzir A. Batista

Journal of Inorganic Biochemistry, 2025, 265, 112819
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Copper(I)/Triphenylphosphine Complexes Containing Naphthoquinone Ligands as Potential Anticancer Agents

Celisnolia M. Leite, João H. Araujo-Neto, Adriana P. M. Guedes, Analu R. Costa, Felipe C. Demidoff, Chaquip D. Netto, Eduardo E. Castellano, Otaciro R. Nascimento and Alzir A. Batista

Inorganics, 2023, 11, 367
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Disruption of the Microtubule Network and Inhibition of VEGFR2 Phosphorylation by Cytotoxic N,O-Coordinated Pt(II) and Ru(II) Complexes of Trimethoxy Aniline-Based Schiff Bases

Sourav Acharya, Moumita Maji, Manas Pratim Chakraborty, Indira Bhattacharya, Rahul Das, Arnab Gupta and Arindam Mukherjee

Inorg. Chem., 2021, 60, 3418
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Advances in the Design of Photoactivatable Metallodrugs: Excited State Metallomics

Huayun Shi, Rafael C. Marchi and Peter J. Sadler

Angewandte Chemie, 2025, 137
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Exploring DNA-interaction and molecular structure of ruthenium/1,2-bis-(diphenylphosphino)ethane)-based complex

Victor Cardoso Campideli, Jerica Margely Montilla-Suárez, Tiago Almeida Silva, Dalila Chaves Sicupira, Katia Mara Oliveira and Rodrigo Souza Correa

Eur. J. Chem., 2023, 14, 193
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Lawsone-Derived Heterocycles: Synthetic Strategies, Structure–Activity Relationships, and Therapeutic Applications

J. P. Sonawane, V. S. Patil, V. K. Suryawanshi, S. S. Nandre, P. M. Raotale and S. R. Patil

Russ J Bioorg Chem, 2026, 52
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Coordination of the natural ligand lapachol to iron(II): synthesis, theoretical study and antiproliferative activity

Tamires D. de Oliveira, Natália A. Cabeza, Gelson T. S. T. da Silva, Ana L. T. G. Ruiz, Anderson R. L. Caires, Rafael G. da Silveira, Daniela C. M. Rodrigues, Antônio R. Fiorucci and Ademir dos Anjos

Transit Met Chem, 2021, 46, 111
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Ruthenium complexes show promise when submitted to toxicological safety tests using alternative methodologies

Thallita Monteiro Teixeira, Isabela Gasparini Arraes, Davi Carvalho Abreu, Katia M. Oliveira, Rodrigo S. Correa, Alzir A. Batista, Thomas Braunbeck and Elisaângela de Paula Silveira Lacerda

European Journal of Medicinal Chemistry, 2021, 216, 113262
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Novel Ru(II)-bipyridine/phenanthroline-lapachol complexes as potential anti-cancer agents

Rone Aparecido De Grandis, Analu Rocha Costa, Carlos André Ferreira Moraes, Natália Zaneti Sampaio, Igor Henrique Cerqueira, Wellington Garcia Marques, Adriana Pereira Mundin Guedes, João Honorato de Araujo-Neto, Fernando Rogério Pavan, Felipe Cerqueira Demidoff, Chaquip Daher Netto, Alzir Azevedo Batista and Flávia Aparecida Resende

Journal of Inorganic Biochemistry, 2022, 237, 112005
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Unlocking the potential of 1,4-naphthoquinones: A comprehensive review of their anticancer properties

Eduardo Angulo-Elizari, Andreina Henriquez-Figuereo, Cristina Morán-Serradilla, Daniel Plano and Carmen Sanmartín

European Journal of Medicinal Chemistry, 2024, 268, 116249
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Exploring the Potential of Metallodrugs as Chemotherapeutics for Triple Negative Breast Cancer

Nazia Nayeem and Maria Contel

Chemistry A European J, 2021, 27, 8891
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A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells

Rone A. De Grandis, Katia M. Oliveira, Adriana P. M. Guedes, Patrick W. S. dos Santos, Alexandre F. Aissa, Alzir A. Batista and Fernando R. Pavan

Front. Oncol., 2021, 11
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Metal(triphenylphosphine)-atovaquone Complexes: Synthesis, Antimalarial Activity, and Suppression of Heme Detoxification

Luana Daniel, Arquímedes Karam, Chris Hebert J. Franco, Camila Conde, Adrielle Sacramento de Morais, Joel Mosnier, Isabelle Fonta, Wilmer Villarreal, Bruno Pradines, Diogo Rodrigo M. Moreira and Maribel Navarro

Inorg. Chem., 2024, 63, 17087
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Selective Ru(II)/benzoate complexes against triple-negative breast tumor cells and their interactions with DNA and BSA

Tamara Teixeira, Gabriel H. Ribeiro, Guilherme R. Gonçalves, João Honorato, Katia M. Oliveira and Rodrigo S. Correa

Inorganica Chimica Acta, 2024, 568, 122078
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Ru(II)-Based Acetylacetonate Complexes Induce Apoptosis Selectively in Cancer Cells

Sayak Gupta, Jessica M. Vandevord, Lauren M. Loftus, Nicholas Toupin, Malik H. Al-Afyouni, Thomas N. Rohrabaugh, Claudia Turro and Jeremy J. Kodanko

Inorg. Chem., 2021, 60, 18964
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Biological Investigations of Ru(II) Complexes with Diverse β‐Diketone Ligands

Raphael T. Ryan, Dmytro Havrylyuk, Kimberly C. Stevens, L. Henry Moore, Sean Parkin, Jessica S. Blackburn, David K. Heidary, John P. Selegue and Edith C. Glazer

Eur J Inorg Chem, 2021, 2021, 3611
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Synthesis, characterization, crystal structures, and toxicity studies of nitro-lawsone, its oxime derivative, and Cu(II) complexes

Manisha Gaikwad, Sunita Salunke-Gawali, Vivek Mokashi, Sukanta Mondal, Ray J. Butcher and Bharathi Prakash

Journal of Molecular Structure, 2025, 1337, 142195
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Direct C–H aminocarbonylation of quinone derivatives with isocyanides under transition-metal free conditions

Yingjie Zhang, Yuxuan Zhao, Jiankang Ou, Zeguo Fang, Qian Zhang and Dong Li

Tetrahedron, 2025, 184, 134779
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Synthesis, characterization of europium(III) and terbium(III) complexes containing lawsone ligand and their interaction with DNA, HSA, and topoisomerases

Josias S. Rocha, George B.S. Pereira, Marcos V. Palmeira-Mello, Willyan F. Oliveira, Jocely L. Dutra, Tamara Teixeira, Nádija N.P. da Silva, Gabriela P. Oliveira, Paulo C. Gomes-Junior, Anna C.S.J. Passaes, João H. Araujo-Neto, Alzir A. Batista, Javier Ellena, José D.L. Dutra, Renan L. Farias and Fillipe V. Rocha

Journal of Molecular Structure, 2025, 1333, 141790
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MiR-874-3p represses the migration and invasion yet promotes the apoptosis and cisplatin sensitivity via being sponged by long intergenic non-coding RNA 00922 (LINC00922) and targeting Glycerophosphodiester Phosphodiesterase Domain Containing 5 (GDPD5) in gastric cancer cells

Xiaoyu Zhang, Xudong Dai, Xin Zhao, Jian Wang, Jin Dou, Haiwen Zhuang, Ning Chen and Haijian Zhao

Bioengineered, 2022, 13, 7082
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Novel glycosylation zinc(II)–cryptolepine complexes perturb mitophagy pathways and trigger cancer cell apoptosis and autophagy in SK-OV-3/DDP cells

Zhen Zhou, Ling-Qi Du, Xiao-Mei Huang, Li-Gang Zhu, Qiao-Chang Wei, Qi-Pin Qin and Hedong Bian

European Journal of Medicinal Chemistry, 2022, 243, 114743
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Impact of ligand esterification on the cytotoxicity against breast cancer cells of ruthenium(II)/dppb pyridinedicarboxylate complexes

Mariana Santoro de Camargo, Rone Aparecido De Grandis, Ayrton Corrêa Galo, Flávia Aparecida Resende, Pedro Henrique Salgado Marcon, Javier Ellena, João Honorato de Araujo-Neto and Alzir Azevedo Batista

Journal of Inorganic Biochemistry, 2025, 272, 113008
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Cytotoxic Ruthenium(II)‐Diphosphine Complexes Affect the Mitochondrial Respiration of Lung Cancer Cells

Marcos V. Palmeira‐Mello, Pierre Mesdom, Pierre Burckel, Samia Hidalgo, Olivier Blacque, Gilles Gasser and Alzir A. Batista

ChemBioChem, 2025, 26
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Experimental and Theoretical DFT Study of Cu(I)/N,N-Disubstituted-N′-acylthioureato Anticancer Complexes: Actin Cytoskeleton and Induction of Death by Apoptosis in Triple-Negative Breast Tumor Cells

Celisnolia M. Leite, João Honorato, Ana Carolina B. M. Martin, Rafael G. Silveira, Felippe M. Colombari, Jéssica C. Amaral, Analu R. Costa, Márcia R. Cominetti, Ana M. Plutín, Debora de Aguiar, Boniek G. Vaz and Alzir A. Batista

Inorg. Chem., 2022, 61, 664
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Scavenging capacity and cytotoxicity of new Ru(II)-diphosphine/α-amino acid complexes

Vivianne S. Velozo-Sa, Regina M.M. Oliveira, Celisnolia M. Leite, Marcia R. Cominetti, Isabely M.M. Barbosa, Fabrício L.S. Silva, Natália Martins Feitosa, Mario S. Schultz and Alzir A. Batista

Polyhedron, 2021, 201, 115169
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State of the art in organometallic ruthenium metallodrugs for breast cancer treatment: Advances and innovations

Elena Domínguez-Jurado, Agustín Lara-Sánchez, Iván Bravo, Alberto Ocaña and Carlos Alonso-Moreno

Coordination Chemistry Reviews, 2025, 523, 216252
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Mn(II), Co(II), and Cu(II) complexes of the iodo derivative of “Heena”: synthesis, characterization, X-crystal structures, and anticancer activity

Sunita Salunke-Gawali, Manisha Gaikwad, Vivek Mokashi, Dipali N. Lande, Shridhar P. Gejji, Harsha Ashtekar and Ray J. Butcher

Inorganica Chimica Acta, 2025, 588, 122837
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New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway

Angelica E. Graminha, Cecília Popolin, João Honorato de Araujo-Neto, Rodrigo S. Correa, Kátia M. de Oliveira, Luani R. Godoy, Legna Colina Vegas, Javier Ellena, Alzir A. Batista and Marcia R. Cominetti

European Journal of Medicinal Chemistry, 2022, 243, 114772
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Advances in the Design of Photoactivatable Metallodrugs: Excited State Metallomics

Huayun Shi, Rafael C. Marchi and Peter J. Sadler

Angew Chem Int Ed, 2025, 64
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Transition metal complexes incorporating lawsone: a review

Freeda Selva Sheela Selvaraj, Michael Samuel, Arunsunai Kumar Karuppiah and Natarajan Raman

Journal of Coordination Chemistry, 2022, 75, 2509
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Anti-tumour signalling pathways and molecular targets of 1,4-naphthoquinone-based natural dyes

Ismail Sami Mahmoud, Hesham Hyari, Ezaldeen Esawi and Walhan Alshaer

Natural Product Research, 2025, 1
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