Fluorescence, ultrasonic and photoacoustic imaging for analysis and diagnosis of diseases

Binbin Chu, Zhiming Chen, Haoliang Shi, Xiaofeng Wu, Houyu Wang, Fenglin Dong and Yao He

Chem. Commun., 2023, 59, 2399
DOI: 10.1039/D2CC06654H

An overview of utilising photo-tunable thiophene scaffolds as luminogens for chemical and biological sensing: progress and prospects

Aakash Venkatesan, Anila Rose Cherian and Aatika Nizam

Analyst, 2025, 150, 5124
DOI: 10.1039/D5AN01012H

Conjugated polymers for biomedical applications

Hongrui Lin, Haotian Bai, Zhiwen Yang, Qi Shen, Mingyu Li, Yiming Huang, Fengting Lv and Shu Wang

Chem. Commun., 2022, 58, 7232
DOI: 10.1039/D2CC02177C

Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications

Chonglu Li, Yida Pang, Yuling Xu, Mengjiao Lu, Le Tu, Qian Li, Amit Sharma, Zhenzhong Guo, Xiangyang Li and Yao Sun

Chem. Soc. Rev., 2023, 52, 4392
DOI: 10.1039/D3CS00227F

The location of metastatic lymph nodes and the evaluation of lymphadenectomy by near-infrared photoacoustic imaging with iridium complex nanoparticles

Qi Yang, Yajun Yu, Chaojie Tang, Yucong Gao, Wu Wang, Zhiguo Zhou, Shiping Yang and Hong Yang

Biomater. Sci., 2023, 11, 2543
DOI: 10.1039/D2BM02044K

Squaraine dyes for biophotonics: sensing, imaging and theranostics

Sivaramapanicker Sreejith, Chodoparambil Sanjay, Balaraman Vedhanarayanan and Ayyappanpillai Ajayaghosh

Chem. Soc. Rev., 2026
DOI: 10.1039/D5CS01375E

Rational design of a selective and sensitive “turn-on” fluorescent probe for monitoring and imaging hydrogen peroxide in living cells

Jing Lu, Liang Ji and Yanyan Yu

RSC Adv., 2021, 11, 35093
DOI: 10.1039/D1RA06620J

Recent advances in self‐immobilizing fluorescent probes for in vivo imaging

Yong Zhang, Xuemei Lv, Yafu Wang, Xueqian Chen, Jinchao Zhang and Dongdong Su

Smart Molecules, 2024, 2
DOI: 10.1002/smo.20240031

Bacterial outer membrane vesicles as cationic dye carriers for optoacoustics-guided phototherapy of cancer

Nian Liu, Vipul Gujrati, Juan Pablo Fuenzalida Werner, Kanuj Mishra, Pia Anzenhofer, Andre C. Stiel, Gabriele Mettenleiter, Annette Feuchtinger, Axel Walch and Vasilis Ntziachristos

Cancer Nano, 2023, 14
DOI: 10.1186/s12645-023-00191-w

Recent development in dual function fluorescence probes for HOCl and interaction with different bioactive molecules

Wajeeha Zareen, Nadeem Ahmed, Shahid Raza, Muhammad Ali Khan and Zahid Shafiq

Talanta, 2024, 277, 126374
DOI: 10.1016/j.talanta.2024.126374

Multifunctional nanotheranostics for near infrared optical imaging-guided treatment of brain tumors

Li Zhang, Yue Liu, Haiyan Huang, Hui Xie, Baozhu Zhang, Wujiong Xia and Bing Guo

Advanced Drug Delivery Reviews, 2022, 190, 114536
DOI: 10.1016/j.addr.2022.114536

Targeted delivery of organic small-molecule photothermal materials with engineered extracellular vesicles for imaging-guided tumor photothermal therapy

Yafang Dong, Peng Xia, Xiaolong Xu, Jing Shen, Youbin Ding, Yuke Jiang, Huifang Wang, Xin Xie, Xiaodong Zhang, Weihua Li, Zhijie Li, Jigang Wang and Shan-Chao Zhao

J Nanobiotechnol, 2023, 21
DOI: 10.1186/s12951-023-02133-5

Tailoring a Near‐Infrared Macrocyclization Scaffold Allows the Control of In Situ Self‐Assembly for Photoacoustic/PET Bimodal Imaging

Yuqi Wang, He Bai, Yinxing Miao, Jianhui Weng, Zheng Huang, Jiayu Fu, Yan Zhang, Jianguo Lin and Deju Ye

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202200369

Multifunctional Upconversion Nanoparticles Transforming Photoacoustic Imaging: A Review

Yuqian Zhang, Zerui Li, Ziqing Du, Jianming Pan and Yanan Huang

Nanomaterials, 2025, 15, 1074
DOI: 10.3390/nano15141074

Photoacoustic Imaging Probes for Theranostic Applications

Cailing He, Jiayuan Zhu, Huayue Zhang, Ruirui Qiao and Run Zhang

Biosensors, 2022, 12, 947
DOI: 10.3390/bios12110947

Tailoring a Near‐Infrared Macrocyclization Scaffold Allows the Control of In Situ Self‐Assembly for Photoacoustic/PET Bimodal Imaging

Yuqi Wang, He Bai, Yinxing Miao, Jianhui Weng, Zheng Huang, Jiayu Fu, Yan Zhang, Jianguo Lin and Deju Ye

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202200369

Mechanism of Amplified Photoacoustic Effect for Silica-Coated Spherical Gold Nanoparticles

Chen Xie, Peiyuan Kang, Jonghae Youn, Blake A. Wilson, Tingting Zhang, Lokesh Basavarajappa, Qingxiao Wang, Moon Kim, Lei Li, Kenneth Hoyt, Jaona Harifidy Randrianalisoa and Zhenpeng Qin

Nano Lett., 2025, 25, 1133
DOI: 10.1021/acs.nanolett.4c05558

Organic Dyes for Light-Based Biomedical Imaging and Therapy

Panangattukara Prabhakaran Praveen Kumar

Colorants, 2026, 5, 10
DOI: 10.3390/colorants5020010

Bispalladium(II) Complexes of di‐p‐Pyrirubyrin Derivatives as Promising Near‐Infrared Photoacoustic Dyes

Karolina Hurej, Weronika Oszczęda, Ewelina Opas, Szymon J. Zelewski, Miłosz Pawlicki, Michał J. Białek, Łukasz Orzeł and Lechosław Latos‐Grażyński

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202303394

Synthesis and luminescence properties of the phenothiazine-functionalized β-diketonate difluoroboron complexes

Hong Li, Yuling Zhao, Di Zhang, Hailin Ma, Minghu Han, Yongchun Guo and Tianzhi Yu

Inorganica Chimica Acta, 2022, 543, 121158
DOI: 10.1016/j.ica.2022.121158

Electronic Characterization of Vis–NIR Absorbing Noninnocent Ruthenium Oxyquinolate–merocyanine Complexes and their Photoacoustic Emission in Aqueous Micellar Solution†

Peter Catsoulis, Shengwei Wang, Chandra Yelleswarapu and Jonathan Rochford

Photochem & Photobiology, 2023, 99, 547
DOI: 10.1111/php.13715

Near-Infrared Fluorescent Nanoparticles from Reactive Polymers for Bioimaging

Wenxuan Wang, Ji Yeon Lee, Jihyo Kil, Taewan Kim, Doh C. Lee, Raisa Kharbash, Yoonsung Nam and Sheng Li

ACS Appl. Polym. Mater., 2025, 7, 10177
DOI: 10.1021/acsapm.5c01953

Small organic molecules-based NIR agents in cancer diagnostics: New frontiers in imaging and therapy

Amal Adnan Ashour, Mohammed Fareed Felemban, Faris J. Tayeb, Abeer Alubaidi and Alaa Shafie

Dyes and Pigments, 2025, 236, 112648
DOI: 10.1016/j.dyepig.2025.112648

A multimodal fluorescent probe for portable colorimetric detection of pH and it’s application in mitochondrial bioimaging

Weifang Luo, Shuan Zhang, Jing Ye, Bohong Jiang, Qinghua Meng, Guanghui Zhang, Jiayi Li and Yuping Tang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 267, 120554
DOI: 10.1016/j.saa.2021.120554

A Comprehensive Review on Photoacoustic-Based Devices for Biomedical Applications

Rita Clarisse Silva Barbosa and Paulo M. Mendes

Sensors, 2022, 22, 9541
DOI: 10.3390/s22239541

Deep and precise lighting-up/combat diseases through sonodynamic agents integrating molecular imaging and therapy modalities

Huocheng Yang, Le Tu, Jie Li, Suya Bai, Zongxing Hu, Peng Yin, Huiyu Lin, Qi Yu, Hongda Zhu and Yao Sun

Coordination Chemistry Reviews, 2022, 453, 214333
DOI: 10.1016/j.ccr.2021.214333

Photostable Red-Emitting Fluorescent Rhein-Magnesium(Ⅱ) Coordination Polymer Nanodot-Based Nanostructures With a Large Stokes Shift for Imaging Mitochondria in Cancer Cell

Qin Jiang, Ke Du, Yuhang Jiang, Yuhan Liu, Chen Han, Zhihui Yin, Ying Wang and Xiaoyan Gao

Front. Oncol., 2021, 11
DOI: 10.3389/fonc.2021.758268

Bridging light and sound: A spironaphtopyran-rhodamine dyad with high-contrast photoswitching between fluorescence and photoacoustic signal

Nikita Kaydanov, Magdalena Olesińska-Mönch, Morgane Leite, Robert Prevedel and Claire Deo

Photoacoustics, 2026, 48, 100809
DOI: 10.1016/j.pacs.2026.100809

BODIPY‐Based Small‐Molecule Photoacoustic Probes for Biomedical Imaging

Kaixuan Song, Hu Gao, Xiaoqing Wang and Zhipeng Liu

ChemPhotoChem, 2025, 9
DOI: 10.1002/cptc.202400335

Recent advances in aggregation-induced emission luminogens in photoacoustic imaging

Pei Li, Xuewen He, Yang Li, Jacky Wing Yip Lam, Ryan Tsz Kin Kwok, Cun Chuan Wang, Li Gang Xia and Ben Zhong Tang

Eur J Nucl Med Mol Imaging, 2022, 49, 2560
DOI: 10.1007/s00259-022-05726-8

Theranostic Polymeric Nanoparticles for Cancer

Donald A. Fernandes

BioNanoSci., 2023, 13, 1609
DOI: 10.1007/s12668-023-01151-9

Engineering organic, inorganic, carbon, and hybrid materials for skin cancer theragnostic: a focus on melanoma and non-melanoma

Pachaiyappan Murugan, Vijayapoopathi Singaravel, Chitrarasu Manikandan, Loganathan Praburaman, Meivelu Moovendhan, Kirubakaran Dharmalingam and Shi-Yong Liu

Microchim Acta, 2026, 193
DOI: 10.1007/s00604-026-07989-6

Near‐Infrared Emission‐Cyanine 5.5 and Doxorubicin Loaded Magnetite Nanoparticles for Dual In Vivo Magnetic Resonance and Biodistribution Imaging

Ke Son Phan, Bich Thuy Doan, Thi Thu Huong Le, Thi Thu Trang Mai, Thi Dieu Thuy Ung, Thuc Quang Bui, Sarah Boumati and Phuong Thu Ha

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202303580

手持式多光谱光声成像探头用于无标记脂质检测及成像性能优化研究（特邀）

于川淼 Yu Chuanmiao, 乔尚 Qiao Shang, 刘良检 Liu Liangjian, 刘成波 Liu Chengbo, 张云尧 Zhang Yunyao and 任亚光 Ren Yaguang

Laser Optoelectron. Prog., 2025, 62, 1817020
DOI: 10.3788/LOP251235

Contrast Agents for Photoacoustic Imaging: A Review Focusing on the Wavelength Range

Seongyi Han, Dakyeon Lee, Sungjee Kim, Hyung-Hoi Kim, Sanghwa Jeong and Jeesu Kim

Biosensors, 2022, 12, 594
DOI: 10.3390/bios12080594

Photoacoustic microscopy for real-time monitoring of near-infrared optical absorbers inside biological tissue

Takeshi Hirasawa, Kazuyoshi Tachi, Tomohiro Ishikawa, Manami Miyashita, Keiichi Ito and Miya Ishihara

J. Biomed. Opt., 2024, 29
DOI: 10.1117/1.JBO.29.S1.S11527

Finely tunable NIR‐II organic scaffolds for fluorescence/photoacoustic duplex imaging–guided noninvasive photothermal therapy of glioblastoma

Yufei Song, Xingyu Tong, Yujie Han and Qi‐Wei Zhang

Aggregate, 2025, 6
DOI: 10.1002/agt2.680

RNA-Seq Explores the Mechanism of Oxygen-Boosted Sonodynamic Therapy Based on All-in-One Nanobubbles to Enhance Ferroptosis for the Treatment of HCC

Yichi Chen, Haitao Shang, Chunyue Wang, Jiaqi Zeng, Shentao Zhang, Bolin Wu and Wen Cheng

IJN, 2022, Volume 17, 105
DOI: 10.2147/IJN.S343361

Golgi-Targeting Fluorescent Probe for Monitoring CO-Releasing Molecule-3 In Vitro and In Vivo

Songjiao Li, Ke Yang, Jiayu Zeng, Yiteng Ding, Dan Cheng and Longwei He

ACS Omega, 2022, 7, 9929
DOI: 10.1021/acsomega.2c00422

NIR-II Fluorescent Molecular Bottlebrush Prepared by Ring-Opening Polymerization for Programmed Cell Death Ligand-1 Checkpoint Imaging

Chao Wang, Pengfei Sun, Quli Fan and Wei Huang

ACS Appl. Polym. Mater., 2021, 3, 5950
DOI: 10.1021/acsapm.1c01216

Multimodal Contrast Agents for Optoacoustic Brain Imaging in Small Animals

Xue-feng Shi, Bin Ji, Yanyan Kong, Yihui Guan and Ruiqing Ni

Front. Bioeng. Biotechnol., 2021, 9
DOI: 10.3389/fbioe.2021.746815

Recent advancements in molecular photoacoustic tomography

Eric Hall, Chengyun Tang and Lei Li

J. Phys. Photonics, 2025, 7, 032003
DOI: 10.1088/2515-7647/adf167

Molecular imaging-guided diagnosis and treatment integration for brain diseases

Donghu Yu, Menghao Liu, Qihang Ding, Youxian Wu, Tianqing Wang, Litong Song, Xiaoyu Li, Kun Qian, Zhen Cheng, Meijia Gu and Zhiqiang Li

Biomaterials, 2025, 316, 123021
DOI: 10.1016/j.biomaterials.2024.123021

A near-infrared photoacoustic probe for specific detection of fluoride ion in vivo

Na Xu, Han Gao, Sisi Wang, Lizhi Gai, Jiangwei Tian, Xinxin Shao and Hua Lu

Dyes and Pigments, 2022, 205, 110536
DOI: 10.1016/j.dyepig.2022.110536

Nanotheranostics: A Cutting-edge Technology for Cancer Management

Shwetapadma Dash, Shasank Sekhar Swain, Auromira Khuntia, Sneha Dutta and Sanjeeb Kumar Sahoo

CPB, 2025, 26, 1099
DOI: 10.2174/0113892010285567240222072959

Cervical cancer imaging with organic small molecule NIR fluorophores: Design strategies and biomedical applications

Pachaiyappan Murugan, Fang Yang, Loganathan Praburaman, Vijayapoopathi Singaravel, Meivelu Moovendhan, Chitrarasu Manikandan and Shi-Yong Liu

Chinese Journal of Structural Chemistry, 2026, 45, 100813
DOI: 10.1016/j.cjsc.2025.100813

Enhanced long-lasting luminescence nanorods for ultrasensitive detection of SARS-CoV-2 N protein

Yi Wei, Menglin Song, Lihua Li, Yingjin Ma, Xinyue Lao, Yuan Liu, Guogang Li and Jianhua Hao

Sci. China Mater., 2025, 68, 253
DOI: 10.1007/s40843-024-3148-9

Recent Progress in Small‐Molecule Fluorescence and Photoacoustic Dual‐Modal Probes for the In‐Vivo Detection of Bioactive Molecules

Yongqing Zhou, Wen Zhang, Xin Wang, Ping Li and Bo Tang

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200155

A caspase-3-activatable bimodal probe for photoacoustic and magnetic resonance imaging of tumor apoptosis in vivo

He Bai, Yuqi Wang, Yuxuan Hu and Deju Ye

Biosensors and Bioelectronics, 2022, 216, 114648
DOI: 10.1016/j.bios.2022.114648

Bispalladium(II) Complexes of di‐p‐Pyrirubyrin Derivatives as Promising Near‐Infrared Photoacoustic Dyes

Karolina Hurej, Weronika Oszczęda, Ewelina Opas, Szymon J. Zelewski, Miłosz Pawlicki, Michał J. Białek, Łukasz Orzeł and Lechosław Latos‐Grażyński

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202303394

Intraperitoneal administration for sustained photoacoustic contrast agent imaging

Hailey I. Kilian, Chenshuo Ma, Huijuan Zhang, Maomao Chen, Anoop Nilam, Breandan Quinn, Yuqi Tang, Jun Xia, Junjie Yao and Jonathan F. Lovell

Photoacoustics, 2022, 28, 100406
DOI: 10.1016/j.pacs.2022.100406

Anion-Mediated Synthesis of Diethynyl-Substituted Doubly N-Confused Dioxohexaphyrin Dyes That Exhibit Enhanced Photoacoustic Signals in the NIR-II Region

Hiroto Kai, Yuma Nakamura, Kotaro Kai, Sandipa Bhandari, Yusuke Notsuka, Shigeki Mori, Tatsuki Abe, Daisuke Kawaguchi, Yoshihisa Yamaoka, Hiroyuki Furuta and Masatoshi Ishida

Org. Lett., 2025, 27, 7218
DOI: 10.1021/acs.orglett.5c02171

Exogenous Contrast Agents in Photoacoustic Imaging: An In Vivo Review for Tumor Imaging

Afifa Farooq, Shafiya Sabah, Salam Dhou, Nour Alsawaftah and Ghaleb Husseini

Nanomaterials, 2022, 12, 393
DOI: 10.3390/nano12030393

Stimuli-Responsive Polymer-Based Nanosystems for Cancer Theranostics

Dengshuai Wei, Yong Sun, Hu Zhu and Qinrui Fu

ACS Nano, 2023, 17, 23223
DOI: 10.1021/acsnano.3c06019

A Renal‐Clearable Activatable Molecular Probe for Fluoro‐Photacoustic and Radioactive Imaging of Cancer Biomarkers

Shenhua Li, Qing Li, Wan Chen, Zhuorun Song, Yi An, Peixin Chen, Yan Wu, Guanglin Wang, Yayi He and Qingqing Miao

Small, 2022, 18
DOI: 10.1002/smll.202201334

Deep learning aided quantitative analysis of anti-tuberculosis fixed-dose combinatorial formulation by terahertz spectroscopy

Jie Liang, Xingxing Lu, Tianying Chang and Hong-Liang Cui

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 269, 120746
DOI: 10.1016/j.saa.2021.120746