Bergaptol, a Major Furocoumarin in Citrus: Pharmacological Properties and Toxicity

Pakkapong Phucharoenrak and Dunyaporn Trachootham

Molecules, 2024, 29, 713
DOI: 10.3390/molecules29030713

Bergaptol inhibits glioma cell proliferation and induces apoptosis via STAT3/Bcl-2 pathway

Hao Huang, Junrong Zhang, Jianbing Wu, Chunfu Du, Bo Zheng, Zhangchao Guo, Ligang Chen, Deming Zhang and Luotong Liu

Anti-Cancer Drugs, 2024, 35, 535
DOI: 10.1097/CAD.0000000000001603

UPLC‐MS/MS and chemometrics analyses reveal chemical profile and anti‐inflammatory activity of Bienertia cycloptera Bunge fractions

Nahla S. El‐Gazzar, Eman Shawky, Doaa A. Ghareeb, Fatma A. A. Mahmoud and Dina A. Selim

Phytochemical Analysis, 2025, 36, 603
DOI: 10.1002/pca.3454

Widely Targeted Metabolomics Analysis Reveals Metabolites Important for Antioxidant Properties and Quality Traits in Different Fruit Parts of Aurantii Fructus Immatures

Shuo Zhang, Ze Liu, Xinyu Xu, Ruihua Zhao, Shujiang Zhang and Rong Luo

Molecules, 2024, 29, 1733
DOI: 10.3390/molecules29081733

Mining Anti-Inflammation Molecules From Nippostrongylus brasiliensis-Derived Products Through the Metabolomics Approach

Yuying Chen, Mingming Zhang, Xin Ding, Yougui Yang, Yujia Chen, Qiang Zhang, Yinwen Fan, Yang Dai and Junhong Wang

Front. Cell. Infect. Microbiol., 2021, 11
DOI: 10.3389/fcimb.2021.781132

Recent Developments in Citrus aurantium L.: An Overview of Bioactive Compounds, Extraction Techniques, and Technological Applications

Joaquín Fernández-Cabal, Kevin Alejandro Avilés-Betanzos, Juan Valerio Cauich-Rodríguez, Manuel Octavio Ramírez-Sucre and Ingrid Mayanin Rodríguez-Buenfil

Processes, 2025, 13, 120
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The underappreciated diversity of furanocoumarins in grapefruits revealed by MassQL filtered molecular networking

Shilin Gong, Guoyu Bai, Yujuan Ban, Meixian Liu, Ying Liu, Yuyao Wu, Na Li and Jian-Lin Wu

Food Chemistry: X, 2025, 25, 102233
DOI: 10.1016/j.fochx.2025.102233

Flowers: precious food and medicine resources

Xuqiang Liu, Senye Wang, Lili Cui, Huihui Zhou, Yuhang Liu, Lijun Meng, Sitan Chen, Xuefeng Xi, Yan Zhang and Wenyi Kang

Food Science and Human Wellness, 2023, 12, 1020
DOI: 10.1016/j.fshw.2022.10.022

Bergaptol Alleviates LPS-Induced Neuroinflammation, Neurological Damage and Cognitive Impairment via Regulating the JAK2/STAT3/p65 Pathway

Jianbing Wu, Jie Zhang, Qiangli Xie, Xiaohuan He, Zhangchao Guo, Bo Zheng, Sisong Wang, Qiumei Yang and Chunfu Du

JIR, 2022, Volume 15, 6199
DOI: 10.2147/JIR.S383853

Bioactivity and multi-omics profiling of purslane-derived nanovesicles with therapeutic implications in diabetic wounds

Yang Song, Fengya Wang, Junhao Xia, Qingwen Zhang, Keman He, Lizhi Wang, Mengru Zhu, Jia Liu, Lukuan Liu and Jing Liu

Journal of Advanced Research, 2025
DOI: 10.1016/j.jare.2025.10.042

Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering

Junmao Li, Yun Luo, Lanlan Zhan, Yongzhe Gu, Wugang Zhang, Quan Wen, Yulin Feng and Ting Tan

Journal of Pharmaceutical and Biomedical Analysis, 2022, 211, 114621
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Targeting Reactive Oxygen Species in Atherosclerosis via Chinese Herbal Medicines

Leyi Zhang, Jiaqin Huang, Danli Zhang, Xiaojing Lei, Yan Ma, Yun Cao, Jingling Chang and Cristina Angeloni

Oxidative Medicine and Cellular Longevity, 2022, 2022
DOI: 10.1155/2022/1852330

Online Extraction–DPPH–HPLC–DAD–QTOF-MS System for Efficient Screening and Identification of Antioxidants from Citrus aurantium L. var. amara (Rutaceae): Integrating Sample Preparation and Antioxidants Profiling

Yecheng Xiao, Fuhua Fu, Youhe Wei, Shuyun Shi and Yang Shan

Antioxidants, 2022, 11, 1014
DOI: 10.3390/antiox11051014

Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway

Xiaoyu Quan, Zhiwei Miao, Runxi Han, Rui Deng, Yaqi Cao, Jingshan Tian, Yaping Lu, Guoxiang Wang, Xingjian Yu, Yi Wu and Chen Dai

Journal of Ethnopharmacology, 2025, 345, 119585
DOI: 10.1016/j.jep.2025.119585

Metabolic profiling of the flower of Citrus aurantium L. var. amara Engl. in rats using ultra‐high‐performance liquid chromatography coupled to quadrupole time‐of‐flight tandem mass spectrometry with data mining strategy

Huixian Zhou, Xinxin Huang, Ting Tan and Yun Luo

Rapid Comm Mass Spectrometry, 2023, 37
DOI: 10.1002/rcm.9607

Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms

Chaoying Zhu, Yuan Gao, Haiying Gong and Jiabo Wang

Chin Med, 2026, 21
DOI: 10.1186/s13020-026-01340-0

Scavenging Glyoxal and Methylglyoxal by Synephrine and Neohesperidin from Flowers of Citrus aurantium L. var. amara Engl. in Mice and Humans

Yu Liang, Xinyu Zhao, Yujia Xu, Yonglin Lu and Lishuang Lv

J. Agric. Food Chem., 2024, 72, 8027
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Bergaptol Alleviates Oxidative Stress and Inflammation in Intracerebral Haemorrhage Mice via JAK2/STAT3 and NF‐κB Pathways, Improving Neurological Function

Jianbing Wu, Zhangchao Guo, Xiaohuan He, Liyuan Yang, Jie Zhang, Lijuan Shu and Chunfu Du

Basic Clin Pharma Tox, 2025, 137
DOI: 10.1111/bcpt.70135

Ingredients with anti-inflammatory effect from medicine food homology plants

Qiuxia Lu, Rui Li, Yixi Yang, Yujin Zhang, Qi Zhao and Jian Li

Food Chemistry, 2022, 368, 130610
DOI: 10.1016/j.foodchem.2021.130610

Guang Chen Pi (the pericarp of Citrus reticulata Blanco's cultivars ‘Chachi’) inhibits macrophage-derived foam cell formation

Pu-Lin Liang, Xue-Lian Chen, Ming-Jiong Gong, Ya Xu, Hai-Sheng Tu, Liang Zhang, Bao-sheng Liao, Xiao-Hui Qiu, Jing Zhang, Zhi-Hai Huang and Wen Xu

Journal of Ethnopharmacology, 2022, 293, 115328
DOI: 10.1016/j.jep.2022.115328

Bergaptol Ameliorates Insulin Sensitivity in Gestational Diabetes Mellitus by Inhibiting the Inflammatory Pathway in Streptozotocin-Induced Diabetic Rats

Q Li, J Chen, X Wang, L Zhuang, Z Yu and D Yang

Physiol Res, 2025, 93
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Natural linear coumarin-heterocyclic conjugates: A review of their roles in phytotherapy

Nameer Mazin Zeki and Yasser Fakri Mustafa

Fitoterapia, 2024, 175, 105929
DOI: 10.1016/j.fitote.2024.105929

Systems Pharmacology Strategy for the Investigation of Action Mechanisms of Qin Herb Libanotis Buchtormensis (Fisch.) DC. in Bone Diseases

Rundong Feng, Lifang Wang, Hu Chai, Jie Jiao, Peng Zhang, Xu Zheng, Haijing Liu, Wenjuan Zhang and Suli Wu

EMIDDT, 2024, 24, 142
DOI: 10.2174/1871530323666230720143415

Is the suppression of CD36 a promising way for atherosclerosis therapy?

Shi-Yuan Wen, Xiaoyan Zhi, Hai-Xin Liu, Xiaohui Wang, Yan-Yan Chen and Li Wang

Biochemical Pharmacology, 2024, 219, 115965
DOI: 10.1016/j.bcp.2023.115965

p-Coumaric acid modulates cholesterol efflux and lipid accumulation and inflammation in foam cells

Ha-Rin Moon and Jung-Mi Yun

Nutr Res Pract, 2024, 18, 774
DOI: 10.4162/nrp.2024.18.6.774

Guidelines for the in vitro determination of anti‐inflammatory activity

Xiujing Huang, Yue Li, Maidinai Sabier, Jinping Si, Pan Wang, Yanghui Shen, Xinfeng Zhang and Jingjing Liu

eFood, 2024, 5
DOI: 10.1002/efd2.160

LKB1 Regulates Vascular Macrophage Functions in Atherosclerosis

Xuewen Wang, Ziwei Liang, Hong Xiang, Yanqiu Li, Shuhua Chen and Hongwei Lu

Front. Pharmacol., 2021, 12
DOI: 10.3389/fphar.2021.810224