A catalytic DNA circuit-programmed and enzyme-powered autonomous DNA machine for nucleic acid detection

Shuang Liu, Chen Xin, Xiaoxiao Yu, Zhenbo Ding and Shufeng Liu

Analyst, 2019, 144, 5923
DOI: 10.1039/C9AN01568J

Engineering high-robustness DNA molecular circuits by utilizing nucleases

Shengnan Fu, Na Li, Junjie Li, Yingnan Deng, Lida Xu, Changyuan Yu and Xin Su

Nanoscale, 2020, 12, 6964
DOI: 10.1039/C9NR09979D

Cytosine-5 methylation-directed construction of a Au nanoparticle-based nanosensor for simultaneous detection of multiple DNA methyltransferases at the single-molecule level

Li-Juan Wang, Xiao Han, Jian-Ge Qiu, BingHua Jiang and Chun-Yang Zhang

Chem. Sci., 2020, 11, 9675
DOI: 10.1039/D0SC03240A

Immuno-DNA binding directed template-free DNA extension and enzyme catalysis for sensitive electrochemical DNA methyltransferase activity assay and inhibitor screening

Ying Zhang, Lijie Hao, Zhen Zhao, Xiaoyan Yang, Li Wang and Shufeng Liu

Analyst, 2020, 145, 3064
DOI: 10.1039/D0AN00008F

Activation of palindromes on a degradable modular grafting probe enables ultrasensitive detection of microRNAs

Jianguo Xu, Zhi Li, Yumei Li, Yusheng Lu and Jie Wang

Chem. Commun., 2021, 57, 5941
DOI: 10.1039/D1CC01150B

A controlled T7 transcription-driven symmetric amplification cascade machinery for single-molecule detection of multiple repair glycosylases

Li-juan Wang, Le Liang, Bing-jie Liu, BingHua Jiang and Chun-yang Zhang

Chem. Sci., 2021, 12, 5544
DOI: 10.1039/D1SC00189B

Proximity-induced exponential amplification reaction triggered by proteins and small molecules

Yu-Peng Zhang, Hong-Peng Wang, Ruo-Lan Dong, Si-Yao Li, Zhi-Gang Wang, Shu-Lin Liu and Dai-Wen Pang

Chem. Commun., 2021, 57, 4714
DOI: 10.1039/D1CC00583A

A versatile single-molecule counting-based platform by generation of fluorescent silver nanoclusters for sensitive detection of multiple nucleic acids

Manshu Peng, Zhuyin Fang, Na Na and Jin Ouyang

Nanoscale, 2019, 11, 16606
DOI: 10.1039/C9NR04608A

A non-enzymatic, isothermal amplification sensor for quantifying the relative abundance of Akkermansia muciniphila

Bing Liu, Chen Shi, Fan Wang, Fangling Xu, Jie Chao, Jiapeng Zhu, Dongliang Yang and Xiangyuan Ouyang

Chem. Commun., 2024, 60, 9089
DOI: 10.1039/D4CC03087G

Trifunctional integrated DNA-based universal sensing platform for detection of diverse biomolecules in one-pot isothermal exponential amplification mode

Yun-Xi Cui, Xue-Nan Feng, Xiao-Yu Li, Yu-Peng Zhang, An-Na Tang and De-Ming Kong

Chem. Commun., 2019, 55, 7603
DOI: 10.1039/C9CC03758F

Plasmonic Au nanocube enhanced SERS biosensor based on heated electrode and strand displacement amplification for highly sensitive detection of Dam methyltransferase activity

Hao-Cheng Hu, Shao-Hua Wu, Lei-Xin Jin and Jian-Jun Sun

Biosensors and Bioelectronics, 2022, 210, 114283
DOI: 10.1016/j.bios.2022.114283

Fluorogenic RNA Aptamer‐Based Amplification and Transcription Strategy for Label‐free Sensing of Methyltransferase Activity in Complex Matrixes

Yu Gu, Cunxia Fan, Hongbin Yang, Huiping Sun, Xiaobao Wang, Xingchen Qiu, Bo Chen, Chang‐Ming Li and Chunxian Guo

Advanced Biology, 2024, 8
DOI: 10.1002/adbi.202300668

Construction of an APE1-Mediated Cascade Signal Amplification Platform for Homogeneously Sensitive and Rapid Measurement of DNA Methyltransferase in Escherichia coli Cells

Yun Han, Chen Wang, Xiaoran Zou, Yan Zhang, Qinfeng Xu and Chun-yang Zhang

Anal. Chem., 2022, 94, 5980
DOI: 10.1021/acs.analchem.2c00439

Droplet digital molecular beacon-LAMP assay via pico-injection for ultrasensitive detection of pathogens

Zhiyuan Ma, Mengshao Ma, Xiaobao Cao, Yuyang Jiang and Dan Gao

Microchim Acta, 2024, 191
DOI: 10.1007/s00604-024-06509-8

Three-input logic gate based on DNA strand displacement reaction

M. A. Jingjing

Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-42383-9

Modular DNA-Incorporated Aggregation-Induced Emission Probe for Sensitive Detection and Imaging of DNA Methyltransferase

Jun Wu, Qinyu Hu, Qing Chen, Jun Dai, Xia Wu, Shixuan Wang, Xiaoding Lou and Fan Xia

ACS Appl. Bio Mater., 2020, 3, 9002
DOI: 10.1021/acsabm.0c01249

Pressure-Based Biosensor Integrated with a Flexible Pressure Sensor and an Electrochromic Device for Visual Detection

Zhenzhong Yu, Guoneng Cai, Xiaolong Liu and Dianping Tang

Anal. Chem., 2021, 93, 2916
DOI: 10.1021/acs.analchem.0c04501

Nonamplification Multiplexed Assay of Endonucleases and DNA Methyltransferases by Colocalized Particle Counting

Guangyu Tao, Xiao Xu, Rong Sheng Li, Feng Liu and Na Li

ACS Sens., 2021, 6, 1321
DOI: 10.1021/acssensors.0c02665

Cascade Strand Displacement and Bipedal Walking Based DNA Logic System for miRNA Diagnostics

Peng Miao and Yuguo Tang

ACS Cent. Sci., 2021, 7, 1036
DOI: 10.1021/acscentsci.1c00277

Catalytic hairpin assembly-assisted CRISPR/Cas12a mediated photoelectrochemical biosensor for sensitive detection of miRNA-122

Xuefeng Wang, Fengyi Wang, Jianrong Wang, Yunqing Liu, Chaomin Gao, Shenguang Ge and Jinghua Yu

Sensors and Actuators B: Chemical, 2022, 370, 132480
DOI: 10.1016/j.snb.2022.132480

Three-way junction-promoted recycling amplification for sensitive DNA detection using highly bright DNA-silver nanocluster as label-free output

Fumiao Shen, He Qian, Yuliang Cheng, Yunfei Xie, Hang Yu, Weirong Yao, Renjun Pei, Yahui Guo and Hung-Wing Li

Talanta, 2020, 206, 120216
DOI: 10.1016/j.talanta.2019.120216

Molecular Logic Gate Based on DNA Strand Displacement Reaction

Jingjing Ma

Journal of Nanoelectronics and Optoelectronics, 2021, 16, 974
DOI: 10.1166/jno.2021.3037

A sensing strategy combining T7 promoter-contained DNA probe with CRISPR/Cas13a for detection of bacteria and human methyltransferase

Yang Yu, Hongwei Zeng, Qiaomin Wu, Xue Jiang, Changyuan Duan, Jinyan Long, Mengqi Chen and Xiaolan Yang

Analytica Chimica Acta, 2022, 1227, 340266
DOI: 10.1016/j.aca.2022.340266

Modular Assembly of a Concatenated DNA Circuit for In Vivo Amplified Aptasensing

Qiong Wu, Lei Yang, Lingling Xie, Jinhua Shang, Shizhen He, Jing Liu and Fuan Wang

Small, 2022, 18
DOI: 10.1002/smll.202200983

Graphene oxide assisted light-up aptamer selection against Thioflavin T for label-free detection of microRNA

Md Mamunul Islam, Victoria Michele Ghielmetti and Peter B. Allen

Sci Rep, 2021, 11
DOI: 10.1038/s41598-021-83640-z

First passage time study of DNA strand displacement

D.W. Bo Broadwater, Alexander W. Cook and Harold D. Kim

Biophysical Journal, 2021, 120, 2400
DOI: 10.1016/j.bpj.2021.01.043

A photocathode based on BiOI-Bi/CNTs for microRNA detection coupling with target recycling strand displacement amplification

Jing Xiao, Keqin Deng, Zhang Liu, Chunxiang Li, Jinglun Wang, Qingfeng Yi, Haowen Huang and Hu Zhou

Sensors and Actuators B: Chemical, 2021, 348, 130691
DOI: 10.1016/j.snb.2021.130691

Terminal deoxynucleotidyl transferase induced activators to unlock the trans-cleavage of CRISPR/Cpf 1 (TdT-IU- CRISPR/Cpf 1): An ultrasensitive biosensor for Dam MTase activity detection

Xiaolong Chen, Gaihua Cao, Xianfeng Wang, Zhong Ji, Faliang Xu, Danqun Huo, Xiaogang Luo and Changjun Hou

Biosensors and Bioelectronics, 2020, 163, 112271
DOI: 10.1016/j.bios.2020.112271

Development of the DNA-based biosensors for high performance in detection of molecular biomarkers: More rapid, sensitive, and universal

Qiong Wang, Jing Wang, Yan Huang, Yichen Du, Yi Zhang, Yunxi Cui and De-ming Kong

Biosensors and Bioelectronics, 2022, 197, 113739
DOI: 10.1016/j.bios.2021.113739

A cascade strand displacement amplification strategy for highly sensitive and label-free detection of DNA methyltransferase activity

Wanling Cui, Guodong Hu, Feng Song, Rui Wang, Zanxia Cao, Junye Zhang, Tiejun Wang, Fanlu Meng, Congcong Shen, Shicai Xu and Jihua Wang

Microchemical Journal, 2021, 160, 105775
DOI: 10.1016/j.microc.2020.105775

Harnessing Demethylase-Regulated Catalytic DNA Circuit for In-Situ Investigation of the Regulatory Connection with MicroRNA

Guangqin Liu, Yifei Wang, Yuqiu He, Mengdi Yu, Xiaoqing Liu and Fuan Wang

Anal. Chem., 2024, 96, 20304
DOI: 10.1021/acs.analchem.4c05225

Terminal deoxynucleotidyl transferase-activated nicking enzyme amplification reaction for specific and sensitive detection of DNA methyltransferase and polynucleotide kinase

Yi-Chen Du, Si-Yuan Wang, Xiao-Yu Li, Ya-Xin Wang, An-Na Tang and De-Ming Kong

Biosensors and Bioelectronics, 2019, 145, 111700
DOI: 10.1016/j.bios.2019.111700

Generation of a high-affinity DNA aptamer for on-site screening of toxic aristolochic acid I in herbal medicines and botanical products

Jiwei Li, Meiqi Chen, Sisi Ke, Jiangwei Tian, Haixiang Yu, Xiufeng Liu and Bo-Yang Yu

Analytica Chimica Acta, 2023, 1264, 341302
DOI: 10.1016/j.aca.2023.341302

A Short- and Long-Range Fluorescence Resonance Energy Transfer-Cofunctionalized Fluorescence Quenching Collapsar Probe Regulates Amplified and Accelerated Detection of Salmonella

Xinlei Zhang, Jianguo Xu, Chao Yan, Li Yao, Huijie Shang and Wei Chen

J. Agric. Food Chem., 2021, 69, 14294
DOI: 10.1021/acs.jafc.1c05780

Methylation-powered engineering of a dual-color light-up RNA nanosensor for label-free and ultrasensitive sensing of multiple DNA methyltransferases

Li-juan Wang, Hao Liu, Xiao-Fang Li, Yingying Meng, Jian-Ge Qiu and Chun-yang Zhang

Sensors and Actuators B: Chemical, 2022, 371, 132524
DOI: 10.1016/j.snb.2022.132524

No-nonspecific recognition-based amplification strategy for endonuclease activity screening with dual-color DNA nano-clew

Zhao-Peng Chen, Hao-Min Zhang, Peng Yang, Ruo Yuan, Yan Li and Wen-Bin Liang

Biosensors and Bioelectronics, 2021, 190, 113446
DOI: 10.1016/j.bios.2021.113446

Cyclometalated Iridium(III) Complex-Sensitized NiO-Based-Cathodic Photoelectrochemical Platform for DNA Methyltransferase Assay

Yueyuan Cai, Yingtao Zhang, Huan Wang, Xiaojia Lin, Kunpeng Yu, Chunxiang Li and Guifen Jie

ACS Appl. Bio Mater., 2021, 4, 6103
DOI: 10.1021/acsabm.1c00445

Functional chimera aptamer and molecular beacon based fluorescent detection of Staphylococcus aureus with strand displacement-target recycling amplification

Rongfeng Cai, Fan Yin, Zhongwen Zhang, Yaping Tian and Nandi Zhou

Analytica Chimica Acta, 2019, 1075, 128
DOI: 10.1016/j.aca.2019.05.014

Highly sensitive detection of the tetracycline resistance gene tetA in water supply systems with an autocatalytic deoxyribonucleic acid–based cascade circuit

RuJie Wang, Yu Zhou, WeiYing Li, HuaJie Liu, Qing Lu and WenHai Chu

Journal of Hazardous Materials, 2025, 492, 138226
DOI: 10.1016/j.jhazmat.2025.138226

Ultrasensitive colorimetric sensing of DNA methyltransferase activity based on signal amplification by modulating cascade reaction

Chao Wang, Lin Jiang, Yong Zhao, Lu Cheng, Lu Zhou, Aihua Liu and Lijun Xu

Sensors and Actuators B: Chemical, 2025, 429, 137298
DOI: 10.1016/j.snb.2025.137298

A fluorescent biosensor based on exponential amplification reaction-initiated CRISPR/Cas12a (EIC) strategy for ultrasensitive DNA methyltransferase detection

Human Sun, Shiying Zhou, Yin Liu, Peng Lu, Na Qi, Guixue Wang, Mei Yang, Danqun Huo and Changjun Hou

Analytica Chimica Acta, 2023, 1239, 340732
DOI: 10.1016/j.aca.2022.340732

Aptamer-based flares hybridized with single-stranded DNA-conjugated MoS2 nanosheets for ratiometric fluorescence sensing and imaging of potassium ions and adenosine triphosphate in human fluids and living cells

Wei-Bin Tseng, Man-Jyun Wu, Chi-Yu Lu, A. Santhana Krishna Kumar and Wei-Lung Tseng

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 309, 123781
DOI: 10.1016/j.saa.2023.123781

Specific Response Assembly of 3D Space-Confined DNA Nanoaggregates for Rapid and Sensitive Detection of DNA Methyltransferase

Jia-Hao Tang, Wei Liu, Mao-Hua Gao, Xian-Ming Guo, Yan-Mei Lei and Ying Zhuo

Anal. Chem., 2024, 96, 20665
DOI: 10.1021/acs.analchem.4c05563

Palindromic Fragment-Mediated Single-Chain Amplification: An Innovative Mode for Photoelectrochemical Bioassay

Ruijin Zeng, Lijia Zhang, Zhongbin Luo and Dianping Tang

Anal. Chem., 2019, 91, 7835
DOI: 10.1021/acs.analchem.9b01557

An Isothermal Autocatalytic Hybridization Reaction Circuit for Sensitive Detection of DNA Methyltransferase and Inhibitors Assay

Fengzhe Li, Yingying Chen, Jinhua Shang, Qing Wang, Shizhen He, Xiwen Xing and Fuan Wang

Anal. Chem., 2022, 94, 4495
DOI: 10.1021/acs.analchem.2c00037

Recent advance in nucleic acid amplification-integrated methods for DNA methyltransferase assay

Wen-jing Liu, Xinyi Zhang, Fei Ma and Chun-yang Zhang

TrAC Trends in Analytical Chemistry, 2023, 160, 116998
DOI: 10.1016/j.trac.2023.116998

Recent advances of fluorescent biosensors based on cyclic signal amplification technology in biomedical detection

Hongke Qu, Chunmei Fan, Mingjian Chen, Xiangyan Zhang, Qijia Yan, Yumin Wang, Shanshan Zhang, Zhaojian Gong, Lei Shi, Xiayu Li, Qianjin Liao, Bo Xiang, Ming Zhou, Can Guo, Guiyuan Li, Zhaoyang Zeng, Xu Wu and Wei Xiong

J Nanobiotechnol, 2021, 19
DOI: 10.1186/s12951-021-01149-z

Programmable High‐Speed and Hyper‐Efficiency DNA Signal Magnifier

Xiao‐Long Zhang, Yang Yin, Shu‐Min Du, Ling‐Qi Kong, Zhe‐Han Yang, Yuan‐Yuan Chang, Ya‐Qin Chai and Ruo Yuan

Advanced Science, 2022, 9
DOI: 10.1002/advs.202104084

Ultrasensitive DNA methyltransferase activity sensing and inhibitor evaluation with highly photostable upconversion nanoparticle transducer

Mingmin Wu, Mengtian Zhang, Zhiwei Fan, Xinyue Qin, Xiaoxia Zhu, Haiwei Ji, Yuling Qin, Qi Wang and Li Wu

Microchim Acta, 2021, 188
DOI: 10.1007/s00604-021-04831-z

Aggregation‐Induced Synergism by Hydrophobic‐Driven Self‐Assembly of Amphiphilic Oligonucleotides

Peng Yang, Xin Peng, Ze‐zhou Yang, Ya‐qin Chai, Ruo Yuan and Wen‐bin Liang

Chemistry A European J, 2020, 26, 8767
DOI: 10.1002/chem.202000099

Sensitivity-Improved SERS Detection of Methyltransferase Assisted by Plasmonically Engineered Nanoholes Array and Hybridization Chain Reaction

Xiaojun Luo, Tuli Kang, Jingtian Zhu, Ping Wu and Chenxin Cai

ACS Sens., 2020, 5, 3639
DOI: 10.1021/acssensors.0c02016

Isothermal nucleic acid amplification and its uses in modern diagnostic technologies

Pulkit Srivastava and Dinesh Prasad

3 Biotech, 2023, 13
DOI: 10.1007/s13205-023-03628-6

An integrated fluorescence biosensor for microRNA detection based on exponential amplification reaction-triggered three-dimensional bipedal DNA walkers

Liu Yang, Jie Fang, Junjie Li, Xinying Ou, Li Zhang, Yufeng Wang, Zhi Weng and Guoming Xie

Analytica Chimica Acta, 2021, 1143, 157
DOI: 10.1016/j.aca.2020.11.043

Enhanced fluorescent detection of nucleic acid based on hairpin DNA-assisted toehold-mediated strand displacement reaction

Yaojia Liu, Yantian Shi, Kexin Ding, Jing Liu, Haiyan Wang and Hong Zhou

Sensors and Actuators B: Chemical, 2023, 385, 133655
DOI: 10.1016/j.snb.2023.133655

Fluorescence biosensor for DNA methyltransferase activity and related inhibitor detection based on methylation-sensitive cleavage primer triggered hyperbranched rolling circle amplification

Liping Chen, Ying Zhang, Qian Xia, Fang Luo, Longhua Guo, Bin Qiu and Zhenyu Lin

Analytica Chimica Acta, 2020, 1122, 1
DOI: 10.1016/j.aca.2020.04.061

A novel methyl-dependent DNA endonuclease GlaI coupling with double cascaded strand displacement amplification and CRISPR/Cas12a for ultra-sensitive detection of DNA methylation

Shiying Zhou, Human Sun, Danqun Huo, Xianfeng Wang, Na Qi, Lan Peng, Mei Yang, Peng Lu and Changjun Hou

Analytica Chimica Acta, 2022, 1212, 339914
DOI: 10.1016/j.aca.2022.339914

Crystal Violet-Sensitized Direct Z-Scheme Heterojunction Coupled with a G-Wire Superstructure for Photoelectrochemical Sensing of Uracil-DNA Glycosylase

Xing Yue Zhang, Lei Han, Ling Dan Yu, Xiao Hu Wang, Yu Ling, Nian Bing Li and Hong Qun Luo

ACS Appl. Mater. Interfaces, 2021, 13, 15881
DOI: 10.1021/acsami.1c01525