The Protein Disulfide Isomerase Family: from proteostasis to pathogenesis

Motonori Matsusaki, Shingo Kanemura, Misaki Kinoshita, Young-Ho Lee, Kenji Inaba and Masaki Okumura

Biochimica et Biophysica Acta (BBA) - General Subjects, 2020, 1864, 129338
DOI: 10.1016/j.bbagen.2019.04.003

Procyanidine resists the fibril formation of human islet amyloid polypeptide

Jufei Xu, Ting Zheng, Xiangyi Huang, Yanan Wang, Guowei Yin and Weihong Du

International Journal of Biological Macromolecules, 2021, 183, 1067
DOI: 10.1016/j.ijbiomac.2021.05.030

Amyloid Protein Cross-Seeding Provides a New Perspective on Multiple Diseases In Vivo

Wan-Yi Ge, Xudong Deng, Wen-Pu Shi, Wen-Juan Lin, Liang-Liang Chen, Huan Liang, Xue-Ting Wang, Tuo-Di Zhang, Feng-Zhu Zhao, Wei-Hong Guo and Da-Chuan Yin

Biomacromolecules, 2023, 24, 1
DOI: 10.1021/acs.biomac.2c01233

Tunable inhibition of β-amyloid peptides by fast green molecules*

Tiantian Yang, Tianxiang Yu, Wenhui Zhao and Dongdong Lin

Chinese Phys. B, 2021, 30, 088701
DOI: 10.1088/1674-1056/ac0690

Three Weaknesses for Three Perturbations: Comparing Protein Unfolding Under Shear, Force, and Thermal Stresses

Olivier Languin-Cattoën, Simone Melchionna, Philippe Derreumaux, Guillaume Stirnemann and Fabio Sterpone

J. Phys. Chem. B, 2018, 122, 11922
DOI: 10.1021/acs.jpcb.8b08711

Zinc boosts EGCG's hIAPP amyloid Inhibition both in solution and membrane

Young-Ho Lee, Yuxi Lin, Sarah J. Cox, Misaki Kinoshita, Bikash R. Sahoo, Magdalena Ivanova and Ayyalusamy Ramamoorthy

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2019, 1867, 529
DOI: 10.1016/j.bbapap.2018.11.006

Bean Extract-Based Gargle for Efficient Diagnosis of Active COVID-19 Infection Using Rapid Antigen Tests

Joseph Kwon, Euna Ko, Se-Young Cho, Young-Ho Lee, Sangmi Jun, Kyuhong Lee, Eunha Hwang, Bipin Vaidya, Jeong-Hwan Hwang, Joo-Hee Hwang, Namsu Kim, Mi-Kyung Song, Hye-Yeon Kim, Dai Ito, Yuxi Lin, Eunae Jo, Kyeong Eun Yang, Hee-Chung Chung, Soyoung Cha, Dong Im Kim, Yoon-Sun Yi, Sung-Ho Yun, Sun Cheol Park, Sangmin Lee, Jong-Soon Choi, Dal Sik Kim, Duwoon Kim and Frederick S. B. Kibenge

Microbiol Spectr, 2022, 10
DOI: 10.1128/spectrum.01614-21

Dynamics and Structures of Amyloid Aggregates under Fluid Flows

Antonio Iorio, Simone Melchionna, Philippe Derreumaux and Fabio Sterpone

J. Phys. Chem. Lett., 2024, 15, 1943
DOI: 10.1021/acs.jpclett.3c03084

Biophysical elucidation of neural network and chemical regeneration of neural tissue

Takahiro Muraoka, Tomohide Saio and Masaki Okumura

BIOPHYSICS, 2022, 19, n/a
DOI: 10.2142/biophysico.bppb-v19.0024

Proteins Do Not Replicate, They Precipitate: Phase Transition and Loss of Function Toxicity in Amyloid Pathologies

Kariem Ezzat, Andrea Sturchio and Alberto J. Espay

Biology, 2022, 11, 535
DOI: 10.3390/biology11040535

Multiscale Aggregation of the Amyloid Aβ16–22 Peptide: From Disordered Coagulation and Lateral Branching to Amorphous Prefibrils

Mara Chiricotto, Simone Melchionna, Philippe Derreumaux and Fabio Sterpone

J. Phys. Chem. Lett., 2019, 10, 1594
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The residues 4 to 6 at the N-terminus in particular modulate fibril propagation of β<sub>2</sub>-microglobulin

Haibin Dang, Zhixian Chen, Wang Chen, Xudong Luo, Pan Liu, Liqiang Wang, Jie Chen, Xuhai Tang, Zhengzhi Wang and Yi Liang

ABBS, 2022, 54, 1
DOI: 10.3724/abbs.2021017

Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses

Abhishek Cukkemane, Nina Becker, Tatsiana Kupreichyk, Henrike Heise, Dieter Willbold and Oliver H. Weiergräber

Journal of Structural Biology: X, 2025, 11, 100128
DOI: 10.1016/j.yjsbx.2025.100128

Structures of the intrinsically disordered Aβ, tau and α-synuclein proteins in aqueous solution from computer simulations

Phuong H. Nguyen and Philippe Derreumaux

Biophysical Chemistry, 2020, 264, 106421
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Can Prions Carry Biological Information?

Kariem Ezzat and Alberto J. Espay

ACS Omega, 2025
DOI: 10.1021/acsomega.5c05830

Ca2+-driven PDIA6 biomolecular condensation ensures proinsulin folding

Young-Ho Lee, Tomohide Saio, Mai Watabe, Motonori Matsusaki, Shingo Kanemura, Yuxi Lin, Taro Mannen, Tsubura Kuramochi, Yuka Kamada, Katsuya Iuchi, Michiko Tajiri, Kotono Suzuki, Yan Li, Yunseok Heo, Kotone Ishii, Kenta Arai, Kazunori Ban, Mayuko Hashimoto, Shuichiro Oshita, Satoshi Ninagawa, Yoshikazu Hattori, Hiroyuki Kumeta, Airu Takeuchi, Shinji Kajimoto, Hiroya Abe, Eiichiro Mori, Takahiro Muraoka, Takakazu Nakabayashi, Satoko Akashi, Tsukasa Okiyoneda, Michele Vendruscolo, Kenji Inaba and Masaki Okumura

Nat Cell Biol, 2025, 27, 1952
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Interactions with tau’s microtubule-binding repeats modulate amyloid-β aggregation and toxicity

Mingeun Kim, Yuxi Lin, Eunju Nam, Dong Min Kang, Sungsu Lim, Yun Kyung Kim, Young-Ho Lee and Mi Hee Lim

Nat Chem Biol, 2025, 21, 1709
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Flavones in pomelo peel resist fibril formation of human islet amyloid polypeptide

Cuiyun Gao, Zhiruo Wan, Yan Liu, Yuting Meng, Xu Chen, Xiaohan Tang, Lingyu Hang and Hailong Yuan

Chinese Herbal Medicines, 2025, 17, 166
DOI: 10.1016/j.chmed.2024.02.002

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis

Phuong H. Nguyen, Ayyalusamy Ramamoorthy, Bikash R. Sahoo, Jie Zheng, Peter Faller, John E. Straub, Laura Dominguez, Joan-Emma Shea, Nikolay V. Dokholyan, Alfonso De Simone, Buyong Ma, Ruth Nussinov, Saeed Najafi, Son Tung Ngo, Antoine Loquet, Mara Chiricotto, Pritam Ganguly, James McCarty, Mai Suan Li, Carol Hall, Yiming Wang, Yifat Miller, Simone Melchionna, Birgit Habenstein, Stepan Timr, Jiaxing Chen, Brianna Hnath, Birgit Strodel, Rakez Kayed, Sylvain Lesné, Guanghong Wei, Fabio Sterpone, Andrew J. Doig and Philippe Derreumaux

Chem. Rev., 2021, 121, 2545
DOI: 10.1021/acs.chemrev.0c01122