P. Rogelio Escamilla, Yanming Shen, Quanjuan Zhang, Derek S. Hernandez, Cecil J. Howard, Xuhong Qian, Daria Y. Filonov, Alexander V. Kinev, Jason B. Shear, Eric V. Anslyn and Youjun Yang

Chem. Sci., 2020, 11, 1394
DOI: 10.1039/C9SC04304G

Au-Ag alloy/porous-SiO2 core/shell nanoparticle-based surface-enhanced Raman scattering nanoprobe for ratiometric imaging analysis of nitric oxide in living cells

Lulu Li, Yanmei Si, Binsheng He and Jishan Li

Talanta, 2019, 205, 120116
DOI: 10.1016/j.talanta.2019.120116

A new interpretation of the mechanism of a fluorescent probe for detecting nitric oxide: invalidity of excited-state intramolecular proton transfer mechanism

Xiaofei Tan, Yue Zhao, Yuxin Zhang, Yi Wang and Peng Zhang

Struct Chem, 2025, 36, 2261
DOI: 10.1007/s11224-025-02516-4

Ex Tenebris Lux: Illuminating Reactive Oxygen and Nitrogen Species with Small Molecule Probes

Maidileyvis C. Cabello, Gen Chen, Michael J. Melville, Rokia Osman, G. Dinesh Kumar, Dylan W. Domaille and Alexander R. Lippert

Chem. Rev., 2024, 124, 9225
DOI: 10.1021/acs.chemrev.3c00892

One Stone, Three Birds: pH Triggered Transformation of Aminopyronine and Iminopyronine Based Lysosome Targeting Viscosity Probe for Cancer Visualization

Yan Song, Hongxing Zhang, Xia Wang, Xin Geng, Yuanqiang Sun, Jing Liu and Zhaohui Li

Anal. Chem., 2021, 93, 1786
DOI: 10.1021/acs.analchem.0c04644

Near infrared fluorescent probes for detecting and imaging active small molecules

Caiping Ding and Tianbing Ren

Coordination Chemistry Reviews, 2023, 482, 215080
DOI: 10.1016/j.ccr.2023.215080

A near‐infrared fluorescent probe based on boric acid hydrolysis for hydrogen peroxide detection and imaging in HeLa cells

Tao Wang, Xiaojun Yang, Jinxia Men, Jinpei Zhou and Huibin Zhang

Luminescence, 2020, 35, 208
DOI: 10.1002/bio.3715

Type I Rhodamine-Sensitized Iridium(III) Complex Photosensitizers Activate Pyroptosis for Hypoxic Photodynamic Immunotherapy

Dongliang Shi, Xianming Zhang, Siye Wu, Luyao Wei, Kai Li and Keith Man-Chung Wong

Inorg. Chem., 2025, 64, 20229
DOI: 10.1021/acs.inorgchem.5c03280

A rhodamine-deoxylactam based fluorescent probe for fast and selective detection of nitric oxide in living cells

Wen-Li Jiang, Yongfei Li, Hong-Wen Liu, Dong-Ye Zhou, Juan Ou-Yang, Lanhua Yi and Chun-Yan Li

Talanta, 2019, 197, 436
DOI: 10.1016/j.talanta.2019.01.061

The optical properties of 9-amino-9H-xanthene derivatives in different pH and their application for biomarkers in lysosome and mitochondria

Xiao Guo, Xue-Rui Wei, Ru Sun, Yu-Jie Xu, Yuan Chen and Jian-Feng Ge

Sensors and Actuators B: Chemical, 2019, 296, 126621
DOI: 10.1016/j.snb.2019.05.098

Development of a Facile Lysosome-Targeting Nitric Oxide Fluorescent Probe Based on a Novel Reaction Mechanism

Wenxiang Wang, Tian Yang, Qinyong Zhang, Kang Lu, Zhonghui Zheng, Cuiqing Tian, Jie Ping, Baiwen Qi and Song Wu

Anal. Chem., 2023, 95, 6279
DOI: 10.1021/acs.analchem.2c04896

Ratiometric two-photon fluorescent probe for detection of hypochlorite in living cells

Qiuyan Li, Zixuan Zhan, Kexin Zhang, Hongjie Song and Yi Lv

Talanta, 2020, 217, 121099
DOI: 10.1016/j.talanta.2020.121099

A novel N-nitrosation-based ratiometric fluorescent probe for highly selective imaging endogenous nitric oxide in living cells and zebrafish

Peilian Liu, Bowen Li, Jian Zheng, Qiqi Liang, Cailing Wu, Liping Huang, Peisheng Zhang, Yongmei Jia and Sheng Wang

Sensors and Actuators B: Chemical, 2021, 329, 129147
DOI: 10.1016/j.snb.2020.129147

Hemicyanine-based turn-off fluorescent probe for monitoring of nitric oxide in living cells

Yong Zhang, Chengli Jia, Yuesong Wang, Haoli Yu and Min Ji

Dyes and Pigments, 2022, 197, 109871
DOI: 10.1016/j.dyepig.2021.109871

Fluorescent pH Indicators for Neutral to Near-Alkaline Conditions Based on 9-Iminopyronin Derivatives

Peter Horváth, Peter Šebej, David Kovář, Jiří Damborský, Zbyněk Prokop and Petr Klán

ACS Omega, 2019, 4, 5479
DOI: 10.1021/acsomega.9b00362

Xanthene dyes for cancer imaging and treatment: A material odyssey

Osman Karaman, Gizem Atakan Alkan, Caglayan Kizilenis, Cevahir Ceren Akgul and Gorkem Gunbas

Coordination Chemistry Reviews, 2023, 475, 214841
DOI: 10.1016/j.ccr.2022.214841

An Activatable Probe with Aggregation‐Induced Emission for Detecting and Imaging Herbal Medicine Induced Liver Injury with Optoacoustic Imaging and NIR‐II Fluorescence Imaging

Lihe Sun, Juan Ouyang, Yunqing Ma, Zhuo Zeng, Cheng Zeng, Fang Zeng and Shuizhu Wu

Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202100867

Bimodal Visualization of Endogenous Nitric Oxide in Lysosomes with a Two-Photon Iridium(III) Phosphorescent Probe

Weijun Wu, Ruilin Guan, Xinxing Liao, Xu Yan, Thomas W. Rees, Liangnian Ji and Hui Chao

Anal. Chem., 2019, 91, 10266
DOI: 10.1021/acs.analchem.9b02415

Far-red to near-infrared fluorescent probes based on silicon-substituted xanthene dyes for sensing and imaging

Mei Zhao, Yu-Shuang Guo, Wei-Na Xu, Yan-Fang Zhao, Han-Yi Xie, Hui-Juan Li, Xiang-Feng Chen, Ru-Song Zhao and Dian-Shun Guo

TrAC Trends in Analytical Chemistry, 2020, 122, 115704
DOI: 10.1016/j.trac.2019.115704

A copper(II) phthalocyanine-based metallo-covalent organic framework decorated with silver nanoparticle for sensitively detecting nitric oxide released from cancer cells

Minghua Wang, Lei Zhu, Shuai Zhang, Yafei Lou, Shuangrun Zhao, Quan Tan, Linghao He and Miao Du

Sensors and Actuators B: Chemical, 2021, 338, 129826
DOI: 10.1016/j.snb.2021.129826

Meso-substituented pyronine: colorful emission and versatile platform for the rational design of fluorescent probes

Deming He, Lishen Zhang and Yuanqiang Sun

Coordination Chemistry Reviews, 2022, 461, 214507
DOI: 10.1016/j.ccr.2022.214507

A Smart Fluorescent Probe for NO Detection and Application in Myocardial Fibrosis Imaging

Tongliang Zhou, Junda Wang, Jiamin Xu, Cangxin Zheng, Yan Niu, Chao Wang, Fengrong Xu, Lan Yuan, Xin Zhao, Lei Liang and Ping Xu

Anal. Chem., 2020, 92, 5064
DOI: 10.1021/acs.analchem.9b05435

Inflammation-responsive near-infrared fluorescence probe for real-time imaging of NO and its antiarthritis evaluation of protopine

Peipei Wang, Hailin Zhang, Renpu Cao, Min Deng, Zibo Zhai, Yufeng Luo, Dan Cheng, Longwei He and Songjiao Li

Sensors and Actuators B: Chemical, 2025, 445, 138556
DOI: 10.1016/j.snb.2025.138556

Simultaneous Detection of Intracellular Nitric Oxide and Peroxynitrite by a Surface-Enhanced Raman Scattering Nanosensor with Dual Reactivity

Hua-Ying Chen, Essy Kouadio Fodjo, Lei Jiang, Shuai Chang, Jia-Bin Li, De-Sheng Zhan, Hai-Xin Gu and Da-Wei Li

ACS Sens., 2019, 4, 3234
DOI: 10.1021/acssensors.9b01740

Selective visualization of nitric oxide in living cells and tissue slices using a mitochondria-targetable fluorescent probe

Changquan Tang, Mingxue Wang, Changfeng Wu and Qingdong Zheng

Dyes and Pigments, 2023, 217, 111443
DOI: 10.1016/j.dyepig.2023.111443

Triarylboron-based fluorescent probe with activatable photosensitivity for lysosomal NO imaging

Bo Zhao, Yu Pu, Caiqiong Zhu, Jian He, Sijie Yan, Hongyu Chen and Jun Liu

Journal of Molecular Structure, 2024, 1313, 138689
DOI: 10.1016/j.molstruc.2024.138689

Far-red to NIR emitting xanthene-based fluorophores

Zeba Khan and Nagaiyan Sekar

Dyes and Pigments, 2023, 208, 110735
DOI: 10.1016/j.dyepig.2022.110735

Recent progress and outlooks in rhodamine-based fluorescent probes for detection and imaging of reactive oxygen, nitrogen, and sulfur species

Ping Yang, A-Ling Tang, Shuai Tan, Guang-Ye Wang, Hou-Yun Huang, Wei Niu, Shi-Tao Liu, Mei-Hong Ge, Lin-Lin Yang, Feng Gao, Xiang Zhou, Li-Wei Liu and Song Yang

Talanta, 2024, 274, 126004
DOI: 10.1016/j.talanta.2024.126004

Lysosome-targeting BODIPY-derived Hantzsch ester for nitric oxide detection and imaging in live cells

Fang Tang, Chang Gao, Jin-Yu Liu, Zhong-Lin Lu, Lan He and Ai-Xiang Ding

Sensors and Actuators B: Chemical, 2021, 339, 129880
DOI: 10.1016/j.snb.2021.129880

A novel ratiometric fluorescent probe with high selectivity for lysosomal nitric oxide imaging

Zhiling Xu, Songtao Liu, Liren Xu, Zichun Li, Xiaoli Zhang, Hao Kang, Yifan Liu, Jin Yu, Jing Jing, Guangle Niu and Xiaoling Zhang

Analytica Chimica Acta, 2024, 1297, 342303
DOI: 10.1016/j.aca.2024.342303

An ESIPT based fluorescence probe for ratiometric monitoring of nitric oxide

Liyan Chen, Di Wu and Juyoung Yoon

Sensors and Actuators B: Chemical, 2018, 259, 347
DOI: 10.1016/j.snb.2017.12.073

A near-infrared fluorescence probe with a large Stokes shift for detecting carbon monoxide in living cells and mice

Yang Liu, Wen-Xin Wang, Yang Tian, Min Tan, Yan Du, Jia Jie and Chun-Yan Li

Dyes and Pigments, 2020, 180, 108517
DOI: 10.1016/j.dyepig.2020.108517

A near-infrared fluorescent probe for detecting hydrogen sulfide and its applications in monitoring food freshness and bioimaging

Zhengkuan Tan, Xiaoyu Zhang, Siqi Kuang, Yuling Zeng, Haichang Ding, Congbin Fan, Gang Liu and Shouzhi Pu

Microchemical Journal, 2025, 209, 112843
DOI: 10.1016/j.microc.2025.112843

Visualizing Nitric oxide in mitochondria and lysosomes of living cells with N-Nitrosation of BODIPY-based fluorescent probes

Zhiliang Yu, Junliang Zhou, Xiaochun Dong, Weili Zhao and Zhongjian Chen

Analytica Chimica Acta, 2019, 1067, 88
DOI: 10.1016/j.aca.2019.03.048

An N-nitrosation reaction-based fluorescent probe for detecting nitric oxide in living cells and inflammatory zebrafish

Qinghai Tang, Peijuan Li, Zile Zhou, Qiujun Lu, Biao Gu, Siping Tang and Youyu Zhang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 270, 120728
DOI: 10.1016/j.saa.2021.120728

Nitric Oxide Signaling and Sensing in Age-Related Diseases

Olga Mazuryk, Ilona Gurgul, Maria Oszajca, Justyna Polaczek, Konrad Kieca, Ewelina Bieszczad-Żak, Tobiasz Martyka and Grażyna Stochel

Antioxidants, 2024, 13, 1213
DOI: 10.3390/antiox13101213

Near-Infrared Fluorescence Probes for Monitoring and Diagnosing Nephron-Urological Diseases

Jing Wang, Zhijia Sheng, Jingru Guo, Hai-Yan Wang, Xiaolian Sun and Yi Liu

Coordination Chemistry Reviews, 2023, 486, 215137
DOI: 10.1016/j.ccr.2023.215137

Optical probes for redox imaging: A comparative review of fluorescent, bioluminescent, and chemiluminescent strategies for in vivo sensing of ROS, RNS, and RSS

Yuhan Wang, Xiaoyu Li, Zhangdong Wang, Peng Wang, Zhen Chen and Jing Yang

Coordination Chemistry Reviews, 2026, 555, 217628
DOI: 10.1016/j.ccr.2026.217628

Nitric Oxide Sensing through 1,2,3,4-Oxatriazole Formation from Acylhydrazide: A Kinetic Study

Abu Saleh Musha Islam, Rahul Bhowmick, Bidhan Chandra Garain, Atul Katarkar and Mahammad Ali

J. Org. Chem., 2018, 83, 13287
DOI: 10.1021/acs.joc.8b02110

Reaction-based small-molecule fluorescent probes for endoplasmic reticulum- and mitochondria-targeted biosensing and bioimaging

Abdul Hadi Mehmood, Faiz Ullah, Baoli Dong and Hong Liu

Sci. China Mater., 2024, 67, 3491
DOI: 10.1007/s40843-024-3097-4

High selective NIR-II fluorescent probe for sensing phosgene in plants

Shuairu Wang, Dongsheng Lian, Chuyang Sun, Minghao Xu, Mingming Zhu, Chenxu Yan and Zhiqian Guo

Chinese Chemical Letters, 2025, 111744
DOI: 10.1016/j.cclet.2025.111744

Efficient Two-Photon Fluorescent Probe for Imaging of Nitric Oxide during Endoplasmic Reticulum Stress

Song-Jiao Li, Dong-Ye Zhou, Yongfei Li, Hong-Wen Liu, Ping Wu, Juan Ou-Yang, Wen-Li Jiang and Chun-Yan Li

ACS Sens., 2018, 3, 2311
DOI: 10.1021/acssensors.8b00567

Luminescent probes for detecting and bioimaging of nitric oxide and carbon monoxide

Guihai Gan, Tengfei Ma, Guoying Zhang, Kewu He and Jinming Hu

TrAC Trends in Analytical Chemistry, 2023, 168, 117340
DOI: 10.1016/j.trac.2023.117340

Engineered dispersed-structural fluorescent nanoprobes enable fast and long-lasting tracking of Nitric oxide in vivo

Yue Wu, Zhiyuan Zheng, Feng Ni, Ayse Basak Kayitmazer, Ayyaz Ahmad, Naveed Ramzan, Wei-Hong Zhu, Tao Xie, Zhiqian Guo and Yisheng Xu

Chemical Engineering Journal, 2025, 504, 158748
DOI: 10.1016/j.cej.2024.158748

Golgi-Targeted Fluorescent Probe for Imaging NO in Alzheimer’s Disease

Zixu He, Diankai Liu, Ya Liu, Xiaohua Li, Wen Shi and Huimin Ma

Anal. Chem., 2022, 94, 10256
DOI: 10.1021/acs.analchem.2c01885

Small molecule fluorescent probes for the detection of reactive nitrogen species in biological systems

Yongqing Zhou, Xiaofeng Yang, Jing zhang, Shuai Xu, Juan Li, Wenshou Wang and Mei Yan

Coordination Chemistry Reviews, 2023, 493, 215258
DOI: 10.1016/j.ccr.2023.215258

Overexpression of RAPGEF3 enhances the therapeutic effect of dezocine in treatment of neuropathic pain

Xue Liu, Li Song, Xiaojun Ma, Yong Liu, Hui Huang, Yongsheng Xu and Wei Yan

Genet. Mol. Biol., 2021, 44
DOI: 10.1590/1678-4685-gmb-2020-0463

Facilitation of molecular motion to develop turn-on photoacoustic bioprobe for detecting nitric oxide in encephalitis

Ji Qi, Leyan Feng, Xiaoyan Zhang, Haoke Zhang, Liwen Huang, Yutong Zhou, Zheng Zhao, Xingchen Duan, Fei Xu, Ryan T. K. Kwok, Jacky W. Y. Lam, Dan Ding, Xue Xue and Ben Zhong Tang

Nat Commun, 2021, 12
DOI: 10.1038/s41467-021-21208-1

Seeing the unseen: NIR probes for reactive nitrogen species biosensing and bioimaging

Meihui Liu, Yiyang Zhou, Ting Luo, Xiaozheng Cao, Duoyang Fan, Shuai Huang, Jie Dong, Fei Chen and Wenbin Zeng

Talanta, 2025, 285, 127334
DOI: 10.1016/j.talanta.2024.127334