Rabbit umbilical cord mesenchymal stem cells: A new option for tissue engineering

Kai‐De Li, Yi Wang, Quan Sun, Mei‐Sheng Li, Jin‐Long Chen and Lei Liu

The Journal of Gene Medicine, 2021, 23
DOI: 10.1002/jgm.3282

Turning Nature’s own processes into design strategies for living bone implant biomanufacturing: a decade of Developmental Engineering

Ioannis Papantoniou, Gabriella Nilsson Hall, Niki Loverdou, Raphaelle Lesage, Tim Herpelinck, Luis Mendes and Liesbet Geris

Advanced Drug Delivery Reviews, 2021, 169, 22
DOI: 10.1016/j.addr.2020.11.012

Bioinspired Development of an In Vitro Engineered Fracture Callus for the Treatment of Critical Long Bone Defects

Johanna Bolander, Carlos Mota, Huey Wen Ooi, Hannah Agten, Matthew B. Baker, Lorenzo Moroni and Frank P. Luyten

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202104159

Decorin-supplemented collagen hydrogels for the co-delivery of bone morphogenetic protein-2 and microvascular fragments to a composite bone-muscle injury model with impaired vascularization

Marissa A. Ruehle, Mon-Tzu Alice Li, Albert Cheng, Laxminarayanan Krishnan, Nick J. Willett and Robert E. Guldberg

Acta Biomaterialia, 2019, 93, 210
DOI: 10.1016/j.actbio.2019.01.045

Engineered 3D mesenchymal stem cell aggregates with multifunctional prowess for bone regeneration: Current status and future prospects

Linxue Zhang, Xiaojing Yuan, Rui Song, Zuoying Yuan, Yuming Zhao and Yunfan Zhang

Journal of Advanced Research, 2026, 79, 409
DOI: 10.1016/j.jare.2025.04.008

Bone Morphogenetic Protein‐2 Promotes Human Mesenchymal Stem Cell Survival and Resultant Bone Formation When Entrapped in Photocrosslinked Alginate Hydrogels

Steve S. Ho, Nina L. Vollmer, Motasem I. Refaat, Oju Jeon, Eben Alsberg, Mark A. Lee and J. Kent Leach

Adv Healthcare Materials, 2016, 5, 2501
DOI: 10.1002/adhm.201600461

Effects of BMP‐2 dose and delivery of microvascular fragments on healing of bone defects with concomitant volumetric muscle loss

Marissa A. Ruehle, Laxminarayanan Krishnan, Casey E. Vantucci, Yuyan Wang, Hazel Y. Stevens, Krishnendu Roy, Robert E. Guldberg and Nick J. Willett

Journal Orthopaedic Research, 2019, 37, 553
DOI: 10.1002/jor.24225

Temperature-sensitive, 1- bromoheptafluorooctane-containing hydrogels in repairing bone defect in rabbits

Qiangjun Kang, Guohui Liu, Changan Liu, Weina Ren and Yuqing Wang

Arabian Journal of Chemistry, 2023, 16, 105202
DOI: 10.1016/j.arabjc.2023.105202

A platform for Bioengineering Tissue Membranes from cell spheroids

Quang Bach Le, Hariharan Ezhilarasu, Weng Wan Chan, Alok Tanala Patra, Priya Murugan, Shashaank Abhinav Venkatesh, Yean Kai Tay, Shin Ru Lim, Ahmad Amirul Abdul Rahim, Jia Sheng Zach Lee, Xuezhi Bi and Deepak Choudhury

Materials Today Bio, 2025, 31, 101526
DOI: 10.1016/j.mtbio.2025.101526

Aggregate mesenchymal stem cell delivery ameliorates the regenerative niche for muscle repair

Marissa A. Ruehle, Hazel Y. Stevens, Aaron M. Beedle, Robert E. Guldberg and Jarrod A. Call

J Tissue Eng Regen Med, 2018, 12, 1867
DOI: 10.1002/term.2707

Recent advances toward understanding the role of transplanted stem cells in tissue-engineered regeneration of musculoskeletal tissues

Dallas E. Altamirano, Kathleen Noller, Eszter Mihaly and Warren L. Grayson

F1000Res, 2020, 9, 118
DOI: 10.12688/f1000research.21333.1

Polymeric Hydrogels as Mesenchymal Stem Cell Secretome Delivery System in Biomedical Applications

Mia Arifka, Gofarana Wilar, Khaled M. Elamin and Nasrul Wathoni

Polymers, 2022, 14, 1218
DOI: 10.3390/polym14061218

Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling

Katherine H. Griffin, Shierly W. Fok and J. Kent Leach

npj Regen Med, 2022, 7
DOI: 10.1038/s41536-022-00266-z

Core-shell oxygen-releasing fibers for annulus fibrosus repair in the intervertebral disc of rats

Yi Zheng, Borui Xue, Bin Wei, Bing Xia, Shengyou Li, Xue Gao, Yiming Hao, Yitao Wei, Lingli Guo, Haining Wu, Yujie Yang, Xueli Gao, Beibei Yu, Yongfeng Zhang, Shijie Yang, Zhuojing Luo, Teng Ma and Jinghui Huang

Materials Today Bio, 2023, 18, 100535
DOI: 10.1016/j.mtbio.2022.100535

Injectable Glucose‐Releasing Microgels Enhance the Survival and Therapeutic Potential of Transplanted MSCs Under Ischemic Conditions

Chieh‐Cheng Huang, Chun‐Kai Chang, Pei‐Ching Yang, Han Chiu, Shih‐Heng Chen and Li‐Wen Hsu

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202401724

Hypoxic Preconditioning of Mesenchymal Stem Cells with Subsequent Spheroid Formation Accelerates Repair of Segmental Bone Defects

Steve S. Ho, Ben P. Hung, Nasser Heyrani, Mark A. Lee and J. Kent Leach

Stem Cells, 2018, 36, 1393
DOI: 10.1002/stem.2853

Engineered Cell‐Secreted Extracellular Matrix Modulates Cell Spheroid Mechanosensing and Amplifies Their Response to Inductive Cues for the Formation of Mineralized Tissues

Tomas Gonzalez‐Fernandez, Alejandro J. Tenorio, Augustine M. Saiz Jr and J. Kent Leach

Adv Healthcare Materials, 2022, 11
DOI: 10.1002/adhm.202102337

Cell spheroids containing bioactive molecule-immobilized porous particles with a leaf-stacked structure

Min Ji Kim, Yeoung Jo Jeoung, Ho Yong Kim, So Young Kim, Jeong Yun Kim, Jae Won Park, June-Ho Byun, Jin Ho Lee and Se Heang Oh

Chemical Engineering Journal, 2022, 429, 132590
DOI: 10.1016/j.cej.2021.132590

Conditioning of myoblast secretome using mesenchymal stem/stromal cell spheroids improves bone repair

Augustine M. Saiz, Marissa A. Gionet-Gonzales, Mark A. Lee and J. Kent Leach

Bone, 2019, 125, 151
DOI: 10.1016/j.bone.2019.05.018

Xenogeneic mesenchymal stem cell transplantation for mandibular defect regeneration

Boon Ching Tee and Zongyang Sun

Xenotransplantation, 2020, 27
DOI: 10.1111/xen.12625

Cell Migration and Bone Formation from Mesenchymal Stem Cell Spheroids in Alginate Hydrogels Are Regulated by Adhesive Ligand Density

Steve S. Ho, Andrew T. Keown, Bennett Addison and J. Kent Leach

Biomacromolecules, 2017, 18, 4331
DOI: 10.1021/acs.biomac.7b01366

Mesenchymal stromal cells for bone trauma, defects, and disease: Considerations for manufacturing, clinical translation, and effective treatments

Annie C. Bowles-Welch, Angela C. Jimenez, Hazel Y. Stevens, David A. Frey Rubio, Linda E. Kippner, Carolyn Yeago and Krishnendu Roy

Bone Reports, 2023, 18, 101656
DOI: 10.1016/j.bonr.2023.101656