Fundamental understanding of the size and surface modification effects on r1, the relaxivity of Prussian blue nanocube@m-SiO2: a novel targeted chemo-photodynamic theranostic agent to treat colon cancer

Panchanan Sahoo, Sudip Kundu, Shubham Roy, S. K. Sharma, Jiten Ghosh, Snehasis Mishra, Abhishek Mukherjee and Chandan Kumar Ghosh

RSC Adv., 2022, 12, 24555
DOI: 10.1039/D2RA03995H

Efficient removal of bisphenol pollutants on imine-based covalent organic frameworks: adsorption behavior and mechanism

Daijun Fu, Qianxin Zhang, Ping Chen, Xiaoshan Zheng, Jun Hao, Peiying Mo, Haijin Liu, Guoguang Liu and Wenying Lv

RSC Adv., 2021, 11, 18308
DOI: 10.1039/D1RA02342J

Prussian blue analogue nanoenzymes mitigate oxidative stress and boost bio-fermentation

Renwu Zhou, Peiyu Wang, Yanru Guo, Xiaofeng Dai, Shaoqing Xiao, Zhi Fang, Robert Speight, Erik W. Thompson, Patrick J. Cullen and Kostya (Ken) Ostrikov

Nanoscale, 2019, 11, 19497
DOI: 10.1039/C9NR04951G

Cu-Chelated polydopamine nanoparticles as a photothermal medium and “immunogenic cell death” inducer for combined tumor therapy

Na Xu, Ao Hu, Ximing Pu, Juan Wang, Xiaoming Liao, Zhongbing Huang and Guangfu Yin

J. Mater. Chem. B, 2022, 10, 3104
DOI: 10.1039/D2TB00025C

Oxidase-mimicking activity of the nitrogen-doped Fe3C@C composites

Hankun Yang, Jingyu Xiao, Lei Su, Ting Feng, Qingye Lv and Xueji Zhang

Chem. Commun., 2017, 53, 3882
DOI: 10.1039/C7CC00610A

A cerium-based metal–organic framework having inherent oxidase-like activity applicable for colorimetric sensing of biothiols and aerobic oxidation of thiols

Rana Dalapati, Balasubramanian Sakthivel, Manoj K. Ghosalya, Amarajothi Dhakshinamoorthy and Shyam Biswas

CrystEngComm, 2017, 19, 5915
DOI: 10.1039/C7CE01053B

Ruptured organosilica nanocapsules immobilized acetylcholinesterase coupled with MnO2 nanozyme for screening inhibitors from Inula macrophylla

Jia Liu, Wei Ha, Eshbakova Komila Alibekovna, Rui Ma and Yan-Ping Shi

Nanoscale, 2023, 15, 17464
DOI: 10.1039/D3NR04025A

Highly selective detection and differentiation of aminophenol isomers based on a bimetallic metal–organic-framework with peroxidase-like activity

Yujie Zhang, Yingjiang Wang, Zhaohui Li, Lingbo Qu and Lanlan Yu

New J. Chem., 2024, 48, 1152
DOI: 10.1039/D3NJ04369J

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)

Jiangjiexing Wu, Xiaoyu Wang, Quan Wang, Zhangping Lou, Sirong Li, Yunyao Zhu, Li Qin and Hui Wei

Chem. Soc. Rev., 2019, 48, 1004
DOI: 10.1039/C8CS00457A

Metal–Organic‐Framework‐Engineered Enzyme‐Mimetic Catalysts

Lang Ma, Fuben Jiang, Xin Fan, Liyun Wang, Chao He, Mi Zhou, Shuang Li, Hongrong Luo, Chong Cheng and Li Qiu

Advanced Materials, 2020, 32
DOI: 10.1002/adma.202003065

Porphyrinic metal-organic framework PCN-224 supported Prussian blue enables selective detection of casein and phytic acid

Zhiqiang Zhou, Xiao Zhang, Wenting Chen, Zhaowei Liang, Zihan Zhang and Liyun Yang

Talanta, 2025, 293, 128121
DOI: 10.1016/j.talanta.2025.128121

Novel Metal Polyphenol Framework for MR Imaging-Guided Photothermal Therapy

Gaozheng Zhao, Huihui Wu, Ruilu Feng, Dongdong Wang, Pengping Xu, Peng Jiang, Kang Yang, Haibao Wang, Zhen Guo and Qianwang Chen

ACS Appl. Mater. Interfaces, 2018, 10, 3295
DOI: 10.1021/acsami.7b16222

Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation

Na Xu, Ao Hu, Ximing Pu, Jiangfeng Li, Xingming Wang, Juan Wang, Zhongbing Huang, Xiaoming Liao and Guangfu Yin

ACS Appl. Mater. Interfaces, 2022, 14, 15894
DOI: 10.1021/acsami.1c24066

Prussian blue: from advanced electrocatalyst to nanozymes defeating natural enzyme

Maria A. Komkova and Arkady A. Karyakin

Microchim Acta, 2022, 189
DOI: 10.1007/s00604-022-05363-w

Anchoring of Prussian blue nanoparticles on polydopamine nanospheres as an efficient peroxidase mimetic for colorimetric sensing

Hongchao Ma, Yingying He, Huan Liu, Lulu Xu, Jiaxuan Li, Mengmeng Huang and Yanhui Wei

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2019, 577, 622
DOI: 10.1016/j.colsurfa.2019.06.035

Recent progress in the design fabrication of metal-organic frameworks-based nanozymes and their applications to sensing and cancer therapy

Xianlong Zhang, Guoliang Li, Di Wu, Xiuling Li, Na Hu, Jian Chen, Guang Chen and Yongning Wu

Biosensors and Bioelectronics, 2019, 137, 178
DOI: 10.1016/j.bios.2019.04.061

Microenvironment engineering of MOFzymes for biomedical applications

Xiaoping Zhao, Rui Gao, Heng Sun, Peng Chen, Haixue Zheng and Lingjie Meng

Coordination Chemistry Reviews, 2025, 533, 216539
DOI: 10.1016/j.ccr.2025.216539

Selenium-functionalized metal-organic frameworks as enzyme mimics

Weiqiang Zhou, Hongfeng Li, Bin Xia, Wenlan Ji, Shaobo Ji, Weina Zhang, Wei Huang, Fengwei Huo and Huaping Xu

Nano Res., 2018, 11, 5761
DOI: 10.1007/s12274-017-1623-2

Xanthine oxidase immobilized cellulose membrane-based colorimetric biosensor for screening and detecting the bioactivity of xanthine oxidase inhibitors

Qi Sun, Wenlong Yu, Mixue Gong, Jingfang Ma, Genyan Liu, Tao Mei and Xiaogang Luo

International Journal of Biological Macromolecules, 2024, 275, 133450
DOI: 10.1016/j.ijbiomac.2024.133450

Development of a Light-Controlled Nanoplatform for Direct Nuclear Delivery of Molecular and Nanoscale Materials

Ya-Xuan Zhu, Hao-Ran Jia, Guang-Yu Pan, Nathan W. Ulrich, Zhan Chen and Fu-Gen Wu

J. Am. Chem. Soc., 2018, 140, 4062
DOI: 10.1021/jacs.7b13672

Electrochemical and sensing properties of Prussian Blue based nanozymes “artificial peroxidase”

Maria A. Komkova, Alexander A. Zarochintsev, Elena E. Karyakina and Arkady A. Karyakin

Journal of Electroanalytical Chemistry, 2020, 872, 114048
DOI: 10.1016/j.jelechem.2020.114048

Potassium cobalt hexacyanoferrate as a peroxidase mimic for electrochemical immunosensing of Lactobacillus rhamnosus GG

Ge Guo, Su-Hui Xu, Yi-Tian Du, Tie-Min Jiang, Jia-Le Song, Zhen-Quan Yang and Ya-Jun Gao

Talanta, 2023, 264, 124746
DOI: 10.1016/j.talanta.2023.124746

EuFe-MOF exhibiting excellent peroxidase-like activity and red fluorescence for colorimetric/fluorescence dual-modal sensor to detect xanthine in aquatic products

Zihan Bian, Pei Liu, Guangze Sun, Huan Liu, Ziting Lin and Aihua Liu

Food Chemistry, 2026, 508, 148293
DOI: 10.1016/j.foodchem.2026.148293

Electrochemical deposition of Prussian blue on Nb2CT MXene modified carbon cloth for the non-enzymatic electrochemical detection of hydrogen peroxide

Ajith Mohan Arjun, Neermunda Shabana, Menon Ankitha and P. Abdul Rasheed

Microchemical Journal, 2023, 185, 108301
DOI: 10.1016/j.microc.2022.108301

Determination of deoxynivalenol (DON) by a label-free electrochemical immunosensor based on Ni Fe PBA nanozymes

Suhui Xu, Tianhao Zhou, Jiamin Wang, Ge Guo, Zhiyan Chen, Huaxiang Li, Zhenquan Yang and Yajun Gao

Food Chemistry, 2025, 463, 141436
DOI: 10.1016/j.foodchem.2024.141436

Nanostructured silver fabric as a free-standing NanoZyme for colorimetric detection of glucose in urine

Md. N. Karim, Samuel R. Anderson, Sanjay Singh, Rajesh Ramanathan and Vipul Bansal

Biosensors and Bioelectronics, 2018, 110, 8
DOI: 10.1016/j.bios.2018.03.025

Metal‐Organic Frameworks: A Potential Platform From Enzyme Immobilization to Mimetic Enzyme

Geling Kuang, Zichen Wang, Muhammad Bilal, Ziyuan Wang, Yuxiao Feng, Yingjie Du and Jiandong Cui

Aggregate, 2025, 6
DOI: 10.1002/agt2.724

Bioinspired Synthesis of Cu2+‐Modified Covalent Triazine Framework: A New Highly Efficient and Promising Peroxidase Mimic

Yuhao Xiong, Yuemei Qin, Linjing Su and Fanggui Ye

Chemistry A European J, 2017, 23, 11037
DOI: 10.1002/chem.201701513

Biomedical Applications of Nanozymes: An Enzymology Perspective

Vasily G. Panferov, Xiaohan Zhang, Ka‐Ying Wong, Jung Heon Lee and Juewen Liu

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202512409

Prussian blue functionalized MIL-101(Cr)-SO3H for Cs+ ion capture for the management of contaminated water

K.J.B. Alloko, L. Cantrel, J. Denis, T. Loiseau, X. Deschanels, J. Causse, A. Moissette, C. Volkringer and A. Grégoire

Microporous and Mesoporous Materials, 2026, 400, 113902
DOI: 10.1016/j.micromeso.2025.113902

Platinum Nanoparticle Encapsulated Metal–Organic Frameworks for Colorimetric Measurement and Facile Removal of Mercury(II)

Huaping Li, Huifang Liu, Jidong Zhang, Yuxiao Cheng, Cuiling Zhang, Xinyu Fei and Yuezhong Xian

ACS Appl. Mater. Interfaces, 2017, 9, 40716
DOI: 10.1021/acsami.7b13695

Acetylcysteine-decorated Prussian blue nanoparticles for strong photothermal sterilization and focal infection treatment

Suya Cai, Jun Qian, Sen Yang, Liangju Kuang and Daoben Hua

Colloids and Surfaces B: Biointerfaces, 2019, 181, 31
DOI: 10.1016/j.colsurfb.2019.05.007

‘Artificial peroxidase’ nanozyme – enzyme based lactate biosensor

Darya V. Vokhmyanina, Ksenia D. Andreeva, Maria A. Komkova, Elena E. Karyakina and Arkady A. Karyakin

Talanta, 2020, 208, 120393
DOI: 10.1016/j.talanta.2019.120393

Recent advances in the construction and analytical applications of metal-organic frameworks-based nanozymes

Siqi Li, Xidong Liu, Hongxiang Chai and Yuming Huang

TrAC Trends in Analytical Chemistry, 2018, 105, 391
DOI: 10.1016/j.trac.2018.06.001

Catalytic nanozymes for central nervous system disease

Ke Chen, Si Sun, Junying Wang and Xiao-Dong Zhang

Coordination Chemistry Reviews, 2021, 432, 213751
DOI: 10.1016/j.ccr.2020.213751

Prussian Blue/Chitosan Micromotors with Intrinsic Enzyme-like Activity for (bio)-Sensing Assays

Roberto María-Hormigos, Águeda Molinero-Fernández, Miguel Ángel López, Beatriz Jurado-Sánchez and Alberto Escarpa

Anal. Chem., 2022, 94, 5575
DOI: 10.1021/acs.analchem.1c05173

Catalytically Synthesized Prussian Blue Nanoparticles Defeating Natural Enzyme Peroxidase

Maria A. Komkova, Elena E. Karyakina and Arkady A. Karyakin

J. Am. Chem. Soc., 2018, 140, 11302
DOI: 10.1021/jacs.8b05223

Rapid in-situ synthesis of metal organic frameworks for biosensors

Juan He, Juan He, Long Tang, Yi Xia, Jiaxin Zhou, Xue Jiang and Xiandeng Hou

TrAC Trends in Analytical Chemistry, 2024, 175, 117709
DOI: 10.1016/j.trac.2024.117709

Protamine-gold nanoclusters as peroxidase mimics and the selective enhancement of their activity by mercury ions for highly sensitive colorimetric assay of Hg(II)

Yan-Qin Huang, Sha Fu, Yong-Sheng Wang, Jin-Hua Xue, Xi-Lin Xiao, Si-Han Chen and Bin Zhou

Anal Bioanal Chem, 2018, 410, 7385
DOI: 10.1007/s00216-018-1344-8

Gold nanoparticle-loaded hollow Prussian Blue nanoparticles with peroxidase-like activity for colorimetric determination of L-lactic acid

Dandan Zhou, Ke Zeng and Minghui Yang

Microchim Acta, 2019, 186
DOI: 10.1007/s00604-018-3214-7

Advances in metal–organic framework-based nanozymes and their applications

Xiang Huang, Songtao Zhang, Yijian Tang, Xinyu Zhang, Yang Bai and Huan Pang

Coordination Chemistry Reviews, 2021, 449, 214216
DOI: 10.1016/j.ccr.2021.214216

New optical method for the determination of β-galactosidase and α-fetoprotein based on oxidase-like activity of fluorescein

Chaoqun Sun, Xia Zhang, Menghuan Tang, Li Liu, Ying Shi, Chunhong Gao, Bing Liao and Huzhi Zheng

Talanta, 2019, 194, 164
DOI: 10.1016/j.talanta.2018.08.075

Three-dimensional MoS2 nanoflowers supported Prussian blue and Au nanoparticles: A peroxidase-mimicking catalyst for the colorimetric detection of hydrogen peroxide and glucose

Lian Ma, Jiao Zhu, Chao Wu, Duo Li, Xuehui Tang, Yue Zhang and Changhua An

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 259, 119886
DOI: 10.1016/j.saa.2021.119886

Recent advances on MOF‐based colorimetric sensors

Solmin Lee, Hyejin Yoo and Jin Yeong Kim

Bulletin Korean Chem Soc, 2025, 46, 918
DOI: 10.1002/bkcs.70066

Elimination of background color interference by immobilizing Prussian blue on carbon cloth: A monolithic peroxidase mimic for on-demand photometric sensing

Xiangheng Niu, Yanfang He, Wenchi Zhang, Xin Li, Fengxian Qiu and Jianming Pan

Sensors and Actuators B: Chemical, 2018, 256, 151
DOI: 10.1016/j.snb.2017.10.072

Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer‐Based Nanocomposites

Amir M. Alsharabasy, Abhay Pandit and Pau Farràs

Advanced Materials, 2021, 33
DOI: 10.1002/adma.202003883

Ion‐Selective Prussian‐Blue‐Modified Celgard Separator for High‐Performance Lithium–Sulfur Battery

Xian Wu, Lishuang Fan, Yue Qiu, Maoxu Wang, Junhan Cheng, Bin Guan, Zhikun Guo, Naiqing Zhang and Kening Sun

ChemSusChem, 2018, 11, 3345
DOI: 10.1002/cssc.201800871

Prussian Blue Nanocubes‐SnO2 Quantum Dots‐Reduced Graphene Oxide Ternary Nanocomposite: An Efficient Non‐noble‐metal Electrocatalyst for Non‐enzymatic Detection of H2O2

Seema Chauhan, Srikant Sahoo, Ashis Kumar Satpati, Chhaya Sharma and Prasanta Kumar Sahoo

Electroanalysis, 2020, 32, 1763
DOI: 10.1002/elan.202000041

Green photoreduction synthesis of dispersible gold nanoparticles and their direct in situ assembling in multidimensional substrates for SERS detection

Zhengyi Chen, Shengyong Lu, Zhi Zhang, Xuemei Huang, Hao Zhao, Jiaxin Wei, Fengling Li, Kunting Yuan, Linjing Su and Yuhao Xiong

Microchim Acta, 2022, 189
DOI: 10.1007/s00604-022-05379-2

Intrinsic Multienzyme-like Activities of the Nanoparticles of Mn and Fe Cyano-Bridged Assemblies

Yunong Zhang, David Kudriashov, Liubov Pershina, Andreas Offenhäusser and Yulia Mourzina

Nanomaterials, 2022, 12, 2095
DOI: 10.3390/nano12122095

Chemiluminescence “Add-and-Measure” Sensing Paper Based on the Prussian Blue/Metal–Organic Framework MIL-101 Nanozyme for Rapid Hydrogen Peroxide Detection

Héctor Martínez-Pérez-Cejuela, Maria Maddalena Calabretta and Elisa Michelini

Anal. Chem., 2024, 96, 16561
DOI: 10.1021/acs.analchem.4c02340

SOD mimics: From the tool box of the chemists to cellular studies

Clotilde Policar, Jean Bouvet, Hélène C. Bertrand and Nicolas Delsuc

Current Opinion in Chemical Biology, 2022, 67, 102109
DOI: 10.1016/j.cbpa.2021.102109

Nanozyme–Cellulose Hydrogel Composites Enabling Cascade Catalysis for the Colorimetric Detection of Glucose

Roberto Baretta, Valeria Gabrielli and Marco Frasconi

ACS Appl. Nano Mater., 2022, 5, 13845
DOI: 10.1021/acsanm.2c01609

Cesium ion-exchange resin using sodium dodecylbenzenesulfonate for binding to Prussian blue

Eunbee Cho, Jeong Jun Lee, Byung-Sik Lee, Kune-Woo Lee, Bongjun Yeom and Taek Seung Lee

Chemosphere, 2020, 244, 125589
DOI: 10.1016/j.chemosphere.2019.125589

Designed inorganic nanomaterials for intrinsic peroxidase mimics: A review

Shunru Jin, Cui Wu, Zunzhong Ye and Yibin Ying

Sensors and Actuators B: Chemical, 2019, 283, 18
DOI: 10.1016/j.snb.2018.10.040

Iron‐Based Nanozymes in Disease Diagnosis and Treatment

Chu Shi, Yan Li and Ning Gu

ChemBioChem, 2020, 21, 2722
DOI: 10.1002/cbic.202000094

A facile one-step synthesis of prussian blue/polyaniline/graphene oxide nanocomposites for electrochemical sensing of hydrogen peroxide

Ziyin Yang, Xiaohui Zheng and Jianbin Zheng

Synthetic Metals, 2016, 221, 153
DOI: 10.1016/j.synthmet.2016.08.020

Oxygen vacancy-rich defective tungsten oxide (WO3−x) modified by Prussian blue for efficient photocatalytic carbon dioxide conversion and tetracycline degradation

Ruolin Cheng, Xiyao Niu, Han Li, Huagen Liang and Panagiotis Tsiakaras

Journal of Colloid and Interface Science, 2025, 683, 807
DOI: 10.1016/j.jcis.2024.12.146

Prussian Blue Nanoparticles as Multienzyme Mimetics and Reactive Oxygen Species Scavengers

Wei Zhang, Sunling Hu, Jun-Jie Yin, Weiwei He, Wei Lu, Ming Ma, Ning Gu and Yu Zhang

J. Am. Chem. Soc., 2016, 138, 5860
DOI: 10.1021/jacs.5b12070

Umbelliferone as a Small Molecular Peroxidase Mimic towards Sensitive Detection of H2O2 and Glucose

Chaoqun Sun, Zili Huang, Li Liu, Menglu Li and Huzhi Zheng

ANAL. SCI., 2018, 34, 933
DOI: 10.2116/analsci.18P023

Metal-organic framework-based nanozymes: From fundamental catalytic mechanisms to rational design of optical sensors for food safety

Kangling Tang, Haoran Shen, Huibin Wang, Yongju Hu, Ailin Tang, Weipeng Liu and Yingju Liu

Microchemical Journal, 2026, 224, 117600
DOI: 10.1016/j.microc.2026.117600

Biomedical Applications of Nanozymes: An Enzymology Perspective

Vasily G. Panferov, Xiaohan Zhang, Ka‐Ying Wong, Jung Heon Lee and Juewen Liu

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202512409

The Preparation of a AuCN/Prussian Blue Nanocube Composite through Galvanic Replacement Enhances Stability for Electrocatalysis.

Baiyu Ren, Lathe A. Jones, Daniel K. Oppedisano, Ahmad Esmaielzadeh Kandjani, Miao Chen, Frank Antolasic, Samuel J. Ippolito and Suresh K. Bhargava

ChemistrySelect, 2017, 2, 5333
DOI: 10.1002/slct.201700908

TiO2-In-MIL-101(Cr) with Visible Light-Induced Peroxidase Activity for Colorimetric Detection of Blood Glucose

Jianwei Lin, Yafeng Zhuang, Jing Chen, Zhizhong Han and Jinghua Chen

ACS Omega, 2022, 7, 45527
DOI: 10.1021/acsomega.2c06176