Lies A. L. Fliervoet, Heyang Zhang, Emma van Groesen, Kyra Fortuin, Naut J. C. B. Duin, Katrien Remaut, Raymond M. Schiffelers, Wim E. Hennink and Tina Vermonden

Nanoscale, 2020, 12, 10347
DOI: 10.1039/D0NR03147J

Enhanced user-control of small molecule drug release from a poly(ethylene glycol) hydrogel via azobenzene/cyclodextrin complex tethers

Eric M. Nehls, Adrianne M. Rosales and Kristi S. Anseth

J. Mater. Chem. B, 2016, 4, 1035
DOI: 10.1039/C5TB02004B

Sustained release of drug-loaded nanoparticles from injectable hydrogels enables long-term control of macrophage phenotype

Shreya S. Soni, Arielle M. D'Elia, Abdulrahman Alsasa, Sylvia Cho, Tina Tylek, Erin M. O'Brien, Ricardo Whitaker, Kara L. Spiller and Christopher B. Rodell

Biomater. Sci., 2022, 10, 6951
DOI: 10.1039/D2BM01113A

Development of a bioactive hyaluronic acid hydrogel functionalised with antimicrobial peptides for the treatment of chronic wounds

Noémie Petit, Ana Gomes, Yu-yin Joanne Chang, Jessica Da Silva, Ermelindo C. Leal, Eugénia Carvalho, Paula Gomes and Shane Browne

Biomater. Sci., 2025, 13, 3561
DOI: 10.1039/D5BM00567A

Polymers and hydrogels for local nucleic acid delivery

Lies A. L. Fliervoet, Johan F. J. Engbersen, Raymond M. Schiffelers, Wim E. Hennink and Tina Vermonden

J. Mater. Chem. B, 2018, 6, 5651
DOI: 10.1039/C8TB01795F

Phosphatidylcholine in the tear film of the eye: Enhanced topical delivery of fluorometholone to the eye

Gholamreza Jafari, Heidar Raissi, Ali Saberinasab and Samaneh Pasban

Inorganic Chemistry Communications, 2023, 150, 110506
DOI: 10.1016/j.inoche.2023.110506

Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels

Adrianne M. Rosales, Christopher B. Rodell, Minna H. Chen, Matthew G. Morrow, Kristi S. Anseth and Jason A. Burdick

Bioconjugate Chem., 2018, 29, 905
DOI: 10.1021/acs.bioconjchem.7b00802

Preparation and characterization of an injectable dexamethasone-cyclodextrin complexes-loaded gellan gum hydrogel for cartilage tissue engineering

Joo Hee Choi, Ain Park, Wonchan Lee, Jina Youn, Min A. Rim, Wooyoup Kim, Namyeong Kim, Jeong Eun Song and Gilson Khang

Journal of Controlled Release, 2020, 327, 747
DOI: 10.1016/j.jconrel.2020.08.049

The Role of Polymeric Biomaterials in the Treatment of Articular Osteoarthritis

Carmen Velasco-Salgado, Gloria María Pontes-Quero, Luis García-Fernández, María Rosa Aguilar, Kyra de Wit, Blanca Vázquez-Lasa, Luis Rojo and Cristina Abradelo

Pharmaceutics, 2022, 14, 1644
DOI: 10.3390/pharmaceutics14081644

Investigating the Association Mechanism between Rafoxanide and Povidone

Fan Meng, Zhifeng Jing, Rui Ferreira, Pengyu Ren and Feng Zhang

Langmuir, 2018, 34, 13971
DOI: 10.1021/acs.langmuir.8b03174

Supramolecular Guest–Host Interactions for the Preparation of Biomedical Materials

Christopher B. Rodell, Joshua E. Mealy and Jason A. Burdick

Bioconjugate Chem., 2015, 26, 2279
DOI: 10.1021/acs.bioconjchem.5b00483

Gamma‐Cyclodextrin‐Recognition‐Responsive Characteristics of Poly(N‐isopropylacrylamide)‐Based Hydrogels with Benzo‐12‐crown‐4 Units as Signal Receptors

Yun‐Yan Wei, Zhuang Liu, Xiao‐Jie Ju, Kun Shi, Rui Xie, Wei Wang, Zhengdong Cheng and Liang‐Yin Chu

Macro Chemistry & Physics, 2017, 218
DOI: 10.1002/macp.201600386

Polysaccharide-based injectable hydrogels for targeted drug delivery: advances and challenges

Xizhi Liao, Jiawei Lu, Jiaxing Yao, Jianping Li, Jin Chen, Jiating Liu and Yi Chen

International Journal of Pharmaceutics, 2026, 690, 126536
DOI: 10.1016/j.ijpharm.2025.126536

Hyaluronic Acid Derivatives for Translational Medicines

Hyemin Kim, Myeonghwan Shin, Seulgi Han, Woosung Kwon and Sei Kwang Hahn

Biomacromolecules, 2019, 20, 2889
DOI: 10.1021/acs.biomac.9b00564

Bioengineered Hyaluronan Hydrogels for the Delivery of Molecular and Cellular Therapies

Joana Silva and Helena S. Azevedo

Advanced Therapeutics, 2024, 7
DOI: 10.1002/adtp.202300182

On the Role of Fertilizer Concentration in Bicontinuous Structures Stabilized by Nanoparticles for the Controlled Delivery of Urea

Fabio Pizzetti, Alessandro Zanino, Stefano Di Rago, Francesco Morandi, Alessandro Marcon, Matteo Testini, Valeria Vanoli, Franca Castiglione, Maurizio Masi and Filippo Rossi

Part & Part Syst Charact, 2025, 42
DOI: 10.1002/ppsc.202500144

Recent advances of injectable hydrogels for drug delivery and tissue engineering applications

Yining Sun, Ding Nan, Haiqiang Jin and Xiaozhong Qu

Polymer Testing, 2020, 81, 106283
DOI: 10.1016/j.polymertesting.2019.106283

Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer

Xianli Hu, Bo Hou, Zhiai Xu, Madiha Saeed, Fang Sun, Zhenmei Gao, Yi Lai, Tong Zhu, Fan Zhang, Wen Zhang and Haijun Yu

Advanced Science, 2020, 7
DOI: 10.1002/advs.201903332

Characteristics of Collagen-Rich Extracellular Matrix Hydrogels and Their Functionalization with Poly(ethylene glycol) Derivatives for Enhanced Biomedical Applications: A Review

Magdalena Rangel-Argote, Jesús A. Claudio-Rizo, José L. Mata-Mata and Birzabith Mendoza-Novelo

ACS Appl. Bio Mater., 2018, 1, 1215
DOI: 10.1021/acsabm.8b00282

Mechano-Triggered Release of Biomolecules from Supramolecular Hyaluronic Acid Hydrogels

Michael A. Maier, Fábio dos Santos Adrego, Shannon A. Jung, Anja M. Boos and Andrij Pich

ACS Appl. Polym. Mater., 2024, 6, 13841
DOI: 10.1021/acsapm.4c02778

Schiff-base based hydrogels as degradable platforms for hydrophobic drug delivery

Esmat Jalalvandi, Lyall R. Hanton and Stephen C. Moratti

European Polymer Journal, 2017, 90, 13
DOI: 10.1016/j.eurpolymj.2017.03.003

Polymer scaffolds as drug delivery systems

Italo Rodrigo Calori, Gustavo Braga, Priscila da Costa Carvalho de Jesus, Hong Bi and Antonio Claudio Tedesco

European Polymer Journal, 2020, 129, 109621
DOI: 10.1016/j.eurpolymj.2020.109621

Injectable liquid polymers extend the delivery of corticosteroids for the treatment of osteoarthritis

Edgardo Rivera-Delgado, Ashley Djuhadi, Chaitanya Danda, Jonathan Kenyon, João Maia, Arnold I. Caplan and Horst A. von Recum

Journal of Controlled Release, 2018, 284, 112
DOI: 10.1016/j.jconrel.2018.05.037

Nanoparticles targeting tumor-associated macrophages: A novel anti-tumor therapy

Siyuan Chen, Furong Qin, Manni Wang, Yuquan Wei, Zhiyong Qian and Xiawei Wei

Nano Res., 2022, 15, 2177
DOI: 10.1007/s12274-021-3781-5

Injectable and protease-degradable hydrogel for siRNA sequestration and triggered delivery to the heart

Leo L. Wang, Jennifer J. Chung, Elizabeth C. Li, Selen Uman, Pavan Atluri and Jason A. Burdick

Journal of Controlled Release, 2018, 285, 152
DOI: 10.1016/j.jconrel.2018.07.004

Modular and Photoreversible Polymer–Nanoparticle Hydrogels via Host–Guest Interactions

Stéphane Bernhard, Lauritz Ritter, Marco Müller, Wenqing Guo, Elia A. Guzzi, Giovanni Bovone and Mark W. Tibbitt

Small, 2024, 20
DOI: 10.1002/smll.202401870

Applications of Macrocyclic Host Molecules in Immune Modulation and Therapeutic Delivery

Shreya S. Soni, Abdulrahman Alsasa and Christopher B. Rodell

Front. Chem., 2021, 9
DOI: 10.3389/fchem.2021.658548

Stimuli-Responsive Hydrogels for Local Post-Surgical Drug Delivery

Esfandyar Askari, Amir Seyfoori, Meitham Amereh, Sadaf Samimi Gharaie, Hanieh Sadat Ghazali, Zahra Sadat Ghazali, Bardia Khunjush and Mohsen Akbari

Gels, 2020, 6, 14
DOI: 10.3390/gels6020014

Tissue engineered drug delivery vehicles: Methods to monitor and regulate the release behavior

Carmen J. Gil, Lan Li, Boeun Hwang, Melissa Cadena, Andrea S. Theus, Tyler A. Finamore, Holly Bauser-Heaton, Morteza Mahmoudi, Ryan K. Roeder and Vahid Serpooshan

Journal of Controlled Release, 2022, 349, 143
DOI: 10.1016/j.jconrel.2022.04.044

Chemical and biological engineering strategies to make and modify next-generation hydrogel biomaterials

Ryan Gharios, Ryan M. Francis and Cole A. DeForest

Matter, 2023, 6, 4195
DOI: 10.1016/j.matt.2023.10.012

Designing Hydrogels for Immunomodulation in Cancer Therapy and Regenerative Medicine

Zhen Zhang, Chaoliang He and Xuesi Chen

Advanced Materials, 2024, 36
DOI: 10.1002/adma.202308894

Sensitivity Enhancement of a Micro Ring Resonator-Based Photonic Sensor by Using a Gelatin Methacryloyl Functional Coating for the Detection of Metoprolol

Anastasia Tsianaka, Christian Schweikert, Alexander Southan, Niklas Hoppe, Markus Greul, Mathias Kaschel, Wolfgang Vogel, Manfred Berroth, Georg Rademacher and Günter E. M. Tovar

ACS Appl. Opt. Mater., 2025, 3, 1556
DOI: 10.1021/acsaom.5c00149

Local and Sustained Baricitinib Delivery to the Skin through Injectable Hydrogels Containing Reversible Thioimidate Adducts

Leo L. Wang, Spencer Tuohy, Karen L. Xu, Arben Nace, Ruifeng Yang, Ying Zheng, Jason A. Burdick and George Cotsarelis

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202303256

Programmable biomaterials for dynamic and responsive drug delivery

Anna Stejskalová, Mehrdad T Kiani and Benjamin D Almquist

Exp Biol Med (Maywood), 2016, 241, 1127
DOI: 10.1177/1535370216649445

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Christopher B. Rodell, Sean P. Arlauckas, Michael F. Cuccarese, Christopher S. Garris, Ran Li, Maaz S. Ahmed, Rainer H. Kohler, Mikael J. Pittet and Ralph Weissleder

Nat Biomed Eng, 2018, 2, 578
DOI: 10.1038/s41551-018-0236-8

Injectable host-guest gel nanovaccine for cancer immunotherapy against melanoma

Kaige Xu, Yuxiang Wen, Xingying Zhang, Yuqing Liu, Ding Qiu, Baohua Li, Lixin Zheng, Yuzhang Wu, Malcolm Xing and Jian Li

Materials Today Advances, 2022, 15, 100236
DOI: 10.1016/j.mtadv.2022.100236

Injectable Supramolecular Hydrogel/Microgel Composites for Therapeutic Delivery

Minna H. Chen, Jennifer J. Chung, Joshua E. Mealy, Samir Zaman, Elizabeth C. Li, Maria F. Arisi, Pavan Atluri and Jason A. Burdick

Macromolecular Bioscience, 2019, 19
DOI: 10.1002/mabi.201800248

(Macro)molecular self-assembly for hydrogel drug delivery

Matthew J. Webber and E. Thomas Pashuck

Advanced Drug Delivery Reviews, 2021, 172, 275
DOI: 10.1016/j.addr.2021.01.006

Self-Illuminating In Situ Hydrogel with Immune-Adjuvant Amplify Cerenkov Radiation-Induced Photodynamic Therapy

Xinmiao Zhang, Jingru Guo, Ziwei Zhou, Kai Feng, Huihui Liu, Yiling Ruan, Ruifang Chen, Zixuan Liu, Tao Zhang, Lijun Tang and Xiaolian Sun

Chemical & Biomedical Imaging, 2024, 2, 275
DOI: 10.1021/cbmi.3c00098

Structurally Dynamic Hydrogels for Biomedical Applications: Pursuing a Fine Balance between Macroscopic Stability and Microscopic Dynamics

Kunyu Zhang, Qian Feng, Zhiwei Fang, Luo Gu and Liming Bian

Chem. Rev., 2021, 121, 11149
DOI: 10.1021/acs.chemrev.1c00071

Macrocyclic Supramolecular Assemblies Based on Hyaluronic Acid and Their Biological Applications

Zhixue Liu, Wenjing Lin and Yu Liu

Acc. Chem. Res., 2022, 55, 3417
DOI: 10.1021/acs.accounts.2c00462

Leveraging Affinity Interactions to Prolong Drug Delivery of Protein Therapeutics

Alan B. Dogan, Katherine E. Dabkowski and Horst A. von Recum

Pharmaceutics, 2022, 14, 1088
DOI: 10.3390/pharmaceutics14051088

Sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischaemic injury

Leo L. Wang, Ying Liu, Jennifer J. Chung, Tao Wang, Ann C. Gaffey, Minmin Lu, Christina A. Cavanaugh, Su Zhou, Rahul Kanade, Pavan Atluri, Edward E. Morrisey and Jason A. Burdick

Nat Biomed Eng, 2017, 1, 983
DOI: 10.1038/s41551-017-0157-y

Polypeptide-based self-healing hydrogels: Design and biomedical applications

Lili Cai, Sa Liu, Jianwei Guo and Yong-Guang Jia

Acta Biomaterialia, 2020, 113, 84
DOI: 10.1016/j.actbio.2020.07.001

Hyaluronic acid-based supramolecular hydrogels for biomedical applications

Marko Mihajlovic, Liline Fermin, Keita Ito, Cornelus F van Nostrum and Tina Vermonden

Multifunct. Mater., 2021, 4, 032001
DOI: 10.1088/2399-7532/ac1c8a

Characterization of Hydrogel Drug Delivery System Stability Using Column-Switching Multimodal Liquid Chromatography–Mass Spectrometry

Brady W. Drennan, Phat Dinh, Kevin A. Schug, Kelly Zhang and Samuel H. Yang

Anal. Chem., 2025, 97, 21827
DOI: 10.1021/acs.analchem.5c01897

Self‐Healing Supramolecular Hydrogels for Tissue Engineering Applications

Laura Saunders and Peter X. Ma

Macromolecular Bioscience, 2019, 19
DOI: 10.1002/mabi.201800313

Engineered Hydrogels for Local and Sustained Delivery of RNA‐Interference Therapies

Leo L. Wang and Jason A. Burdick

Adv Healthcare Materials, 2017, 6
DOI: 10.1002/adhm.201601041

Near-Infrared Light Triggered Release of Molecules from Supramolecular Hydrogel-Nanorod Composites

Christopher B Highley, Miju Kim, Daeyeon Lee and Jason A Burdick

Nanomedicine (Lond.), 2016, 11, 1579
DOI: 10.2217/nnm-2016-0070

Recent advances in hyaluronic acid hydrogels for biomedical applications

Christopher B Highley, Glenn D Prestwich and Jason A Burdick

Current Opinion in Biotechnology, 2016, 40, 35
DOI: 10.1016/j.copbio.2016.02.008

On the Race for More Stretchable and Tough Hydrogels

Santiago Grijalvo, Ramon Eritja and David Díaz Díaz

Gels, 2019, 5, 24
DOI: 10.3390/gels5020024

A novel amorphous solid dispersion based on drug–polymer complexation

Fan Meng, Rui Ferreira, Yongchao Su and Feng Zhang

Drug Deliv. and Transl. Res., 2021, 11, 2072
DOI: 10.1007/s13346-020-00869-3

Supramolecular Hydrogels: Design Strategies and Contemporary Biomedical Applications

Jasmin Omar, Daniel Ponsford, Cécile A. Dreiss, Tung‐Chun Lee and Xian Jun Loh

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200081

Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

Sepehr Talebian, Mehdi Mehrali, Nayere Taebnia, Cristian Pablo Pennisi, Firoz Babu Kadumudi, Javad Foroughi, Masoud Hasany, Mehdi Nikkhah, Mohsen Akbari, Gorka Orive and Alireza Dolatshahi‐Pirouz

Advanced Science, 2019, 6
DOI: 10.1002/advs.201801664

Cytokine Therapy Combined with Nanomaterials Participates in Cancer Immunotherapy

Heping Lian, Shuang Ma, Duoyi Zhao, Wei Zhao, Yan Cui, Yingqi Hua and Zhiyu Zhang

Pharmaceutics, 2022, 14, 2606
DOI: 10.3390/pharmaceutics14122606

3D printing of hydrogels: Rational design strategies and emerging biomedical applications

Jinhua Li, Chengtie Wu, Paul K. Chu and Michael Gelinsky

Materials Science and Engineering: R: Reports, 2020, 140, 100543
DOI: 10.1016/j.mser.2020.100543

The potential of hyaluronic acid in immunoprotection and immunomodulation: Chemistry, processing and function

Fernanda Zamboni, Silvia Vieira, Rui L. Reis, J. Miguel Oliveira and Maurice N. Collins

Progress in Materials Science, 2018, 97, 97
DOI: 10.1016/j.pmatsci.2018.04.003

Supramolecular Host–Guest Hydrogels for Corneal Regeneration

Amy C. Madl and David Myung

Gels, 2021, 7, 163
DOI: 10.3390/gels7040163

Multiple release of fertilizers and pesticides from biodegradable bicontinuous structures

Fabio Pizzetti, Valeria Vanoli, Roberta Magaletti, Liebert Parreiras Nogueira, Simone Gelosa, Håvard Jostein Haugen, Franca Castiglione, Ehsan Nazarzadeh Zare, Pooyan Makvandi and Filippo Rossi

Journal of Industrial and Engineering Chemistry, 2025, 150, 347
DOI: 10.1016/j.jiec.2025.02.053

Injectable hyaluronic acid–cyclodextrin-based hydrogels for localized and sustained release of anticancer drugs

Dinh Trung Nguyen, Le Hang Dang, Hai Khoa Le, Lien Tuyet Ngan, Ngoc Quyen Tran, Ki Dong Park and Phuong Le Thi

Macromol. Res., 2024, 32, 777
DOI: 10.1007/s13233-024-00262-w

Combination Therapy of Killing Diseases by Injectable Hydrogels: From Concept to Medical Applications

Fatemeh Poustchi, Hamed Amani, Zainab Ahmadian, Seyyed Vahid Niknezhad, Soraya Mehrabi, Hélder A. Santos and Mohammad‐Ali Shahbazi

Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202001571

Dual cross-linked hydrogels as promising materials for drug delivery

Carsten Damm and Achim Goepferich

International Journal of Pharmaceutics, 2025, 683, 125929
DOI: 10.1016/j.ijpharm.2025.125929

Cell receptor screening for human papillomavirus invasion by using a polyoxometalate-peptide assembly as a probe

Peng-Fan Gao, Yu-Xue Liu, Lening Zhang, Simin Zhang, Hong-Wei Li, Yuqing Wu and Lixin Wu

Journal of Colloid and Interface Science, 2018, 514, 407
DOI: 10.1016/j.jcis.2017.12.055

Tunable biohybrid hydrogels from coacervation of hyaluronic acid and PEO‐based block copolymers

Mathijs F. J. Mabesoone, Jeffrey D. Gopez, Ilka E. Paulus and Daniel Klinger

Journal of Polymer Science, 2020, 58, 1276
DOI: 10.1002/pol.20200081

In situ forming injectable hydrogels for drug delivery and wound repair

Robert Dimatteo, Nicole J. Darling and Tatiana Segura

Advanced Drug Delivery Reviews, 2018, 127, 167
DOI: 10.1016/j.addr.2018.03.007

Injectable Granular Hydrogels with Multifunctional Properties for Biomedical Applications

Joshua E. Mealy, Jennifer J. Chung, Heon‐Ho Jeong, David Issadore, Daeyeon Lee, Pavan Atluri and Jason A. Burdick

Advanced Materials, 2018, 30
DOI: 10.1002/adma.201705912

Cyclodextrin-polyhydrazine degradable gels for hydrophobic drug delivery

Esmat Jalalvandi, Jaydee Cabral, Lyall R. Hanton and Stephen C. Moratti

Materials Science and Engineering: C, 2016, 69, 144
DOI: 10.1016/j.msec.2016.06.058

Injectable Granular Hydrogels Enable Avidity-Controlled Biotherapeutic Delivery

Arielle M. D’Elia, Olivia L. Jones, Gabriela Canziani, Biplab Sarkar, Irwin Chaiken and Christopher B. Rodell

ACS Biomater. Sci. Eng., 2024, 10, 1577
DOI: 10.1021/acsbiomaterials.3c01906

Development of a multifunctional, injectable biomaterial using hyaluronan as a bioactive nanocarrier

Louis S. Paone, Ying Jin, Julien Bouyer, Itzhak Fischer and Peter A. Galie

Biomaterials, 2026, 324, 123505
DOI: 10.1016/j.biomaterials.2025.123505

Glycosaminoglycan‐Based Biohybrid Hydrogels: A Sweet and Smart Choice for Multifunctional Biomaterials

Uwe Freudenberg, Yingkai Liang, Kristi L. Kiick and Carsten Werner

Advanced Materials, 2016, 28, 8861
DOI: 10.1002/adma.201601908

A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart

Maaz S. Ahmed, Christopher B. Rodell, Maarten Hulsmans, Rainer H. Kohler, Aaron D. Aguirre, Matthias Nahrendorf and Ralph Weissleder

Bioconjugate Chem., 2019, 30, 733
DOI: 10.1021/acs.bioconjchem.8b00882

Shear-Thinning Hydrogel for Delayed Delivery of a Small Molecule Metalloproteinase Inhibitor Attenuates Myocardial Infarction Remodeling

Joshua E. Mealy, William M. Torres, Lisa A. Freeburg, Shayne C. Barlow, Alison A. Whalen, Chima V. Maduka, Tarek M. Shazly, Jason A. Burdick and Francis G. Spinale

JACC: Basic to Translational Science, 2025, 10, 458
DOI: 10.1016/j.jacbts.2024.11.009

Supramolecular engineering of hydrogels for drug delivery

Stéphane Bernhard and Mark W. Tibbitt

Advanced Drug Delivery Reviews, 2021, 171, 240
DOI: 10.1016/j.addr.2021.02.002

Shear-thinning and self-healing hydrogels as injectable therapeutics and for 3D-printing

Claudia Loebel, Christopher B Rodell, Minna H Chen and Jason A Burdick

Nat Protoc, 2017, 12, 1521
DOI: 10.1038/nprot.2017.053

Injectable network biomaterials via molecular or colloidal self-assembly

Jugal Kishore Sahoo, Michael A. VandenBerg and Matthew J. Webber

Advanced Drug Delivery Reviews, 2018, 127, 185
DOI: 10.1016/j.addr.2017.11.005

Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions

Peilin Lu, Dongxue Ruan, Meiqi Huang, Mi Tian, Kangshun Zhu, Ziqi Gan and Zecong Xiao

Sig Transduct Target Ther, 2024, 9
DOI: 10.1038/s41392-024-01852-x

A suturable biohydrogel with mechanical matched property based on coating chitosan and polyethylene glycol shell for tissue patching

Yimei Yang, Tian Hu, Hongyan Zhang, Bu-Ning Liu, Jinwen Liu, Wei-Xiong Li, Kui Song and Gang-Biao Jiang

International Journal of Biological Macromolecules, 2023, 224, 523
DOI: 10.1016/j.ijbiomac.2022.10.141

Assembling a supramolecular 3D network with tuneable mechanical properties using adamantylated cross-linking agents and β-cyclodextrin-modified hyaluronan

Marek Jurtík, Barbora Gřešková, Zdeňka Prucková, Michal Rouchal, Lenka Dastychová, Lenka Vítková, Kristýna Valášková, Eva Achbergerová and Robert Vícha

Carbohydrate Polymers, 2023, 313, 120872
DOI: 10.1016/j.carbpol.2023.120872

Recent Advances in Host‐Guest Supramolecular Hydrogels for Biomedical Applications

Suxi Wang, Pin Jin Ong, Songlin Liu, Warintorn Thitsartarn, Maureen Janet Beng Hoon Tan, Ady Suwardi, Qiang Zhu and Xian Jun Loh

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200608

Hyaluronic acid as a versatile building block for the development of biofunctional hydrogels: In vitro models and preclinical innovations

Noémie Petit, Yu-yin Joanne Chang, Franz Acker Lobianco, Tom Hodgkinson and Shane Browne

Materials Today Bio, 2025, 31, 101596
DOI: 10.1016/j.mtbio.2025.101596

Local Affinity Release

Vianney Delplace, Jaclyn Obermeyer and Molly S. Shoichet

ACS Nano, 2016, 10, 6433
DOI: 10.1021/acsnano.6b04308

Diatoms embedded, self-assembled carriers for dual delivery of chemotherapeutics in cancer cell lines

Anayet Kabir, Nauman Nazeer, Rabin Bissessur and Marya Ahmed

International Journal of Pharmaceutics, 2020, 573, 118887
DOI: 10.1016/j.ijpharm.2019.118887

Fabricating ternary hydrogels of P(AM-co-DMAEMA)/PVA/ β -CD based on multiple physical crosslinkage

Jia-Min Li, Chuan-Shan Hu, Jian-Ming Shao, Hui-Juan Li, Peng-Yun Li, Xi-Chuan Li and Wei-Dong He

Polymer, 2017, 119, 152
DOI: 10.1016/j.polymer.2017.05.031

Development of Biocompatible HA Hydrogels Embedded with a New Synthetic Peptide Promoting Cellular Migration for Advanced Wound Care Management

Sun Young Wang, Hyosuk Kim, Gijung Kwak, Hong Yeol Yoon, Sung Duk Jo, Ji Eun Lee, Daeho Cho, Ick Chan Kwon and Sun Hwa Kim

Advanced Science, 2018, 5
DOI: 10.1002/advs.201800852

Injectable immunogel based on polymerized phenylboronic acid and mannan for cancer immunotherapy

Seonil Kim, Junseok Lee, Sooseok Im and Won Jong Kim

Journal of Controlled Release, 2022, 345, 138
DOI: 10.1016/j.jconrel.2022.03.009

Prospective and challenges of locally applied repurposed pharmaceuticals for periodontal tissue regeneration

Mohammad El-Nablaway, Fatema Rashed, Ehab S. Taher, Ahmed Abdeen, Noha Taymour, Magdalen M. Soliman, Hany K. Shalaby, Liana Fericean, Bănățean-Dunea Ioan, Mohamed El-Sherbiny, Elturabi Ebrahim, Afaf Abdelkader, Mohamed Abdo, Cucui-Cozma Alexandru and Gamal A. Atia

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1400472

Cyclodextrins as versatile building blocks for regenerative medicine

Carmen Alvarez-Lorenzo, Carlos A. García-González and Angel Concheiro

Journal of Controlled Release, 2017, 268, 269
DOI: 10.1016/j.jconrel.2017.10.038

Hypoxia-modulatory nanomaterials to relieve tumor hypoxic microenvironment and enhance immunotherapy: Where do we stand?

Cong-Shan Yuan, Zhen-Wei Deng, Di Qin, Yu-Zhi Mu, Xi-Guang Chen and Ya Liu

Acta Biomaterialia, 2021, 125, 1
DOI: 10.1016/j.actbio.2021.02.030

A supramolecular host-guest interaction-mediated injectable hydrogel system with enhanced stability and sustained protein release

Seung Yong Lee, Seong Ik Jeon, Sung Bo Sim, Youngro Byun and Cheol-Hee Ahn

Acta Biomaterialia, 2021, 131, 286
DOI: 10.1016/j.actbio.2021.07.004

In situ forming gelatin: Cyclodextrin hydrogels prepared by “click chemistry” to improve the sustained release of hydrophobic drugs

Phuong Le Thi, Thi Yen Nhi Tran, Hung Cuong Luu, Dieu Linh Tran, Thai Thanh Hoang Thi and Dai Hai Nguyen

Journal of Bioactive and Compatible Polymers, 2022, 37, 252
DOI: 10.1177/08839115221098058

Recent Updates on Supramolecular‐Based Drug Delivery – Macrocycles and Supramolecular Gels

Viswanathan S. Saji

The Chemical Record, 2022, 22
DOI: 10.1002/tcr.202200053

Recent Advances in Host–Guest Self‐Assembled Cyclodextrin Carriers: Implications for Responsive Drug Delivery and Biomedical Engineering

Jitendra Wankar, Niranjan G. Kotla, Sonia Gera, Swetha Rasala, Abhay Pandit and Yury A. Rochev

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.201909049

Injectable hyaluronic acid hydrogels encapsulating drug nanocrystals for long‐term treatment of inflammatory arthritis

Yongsheng Gao, Douglas Vogus, Zongmin Zhao, Wei He, Vinu Krishnan, Jayoung Kim, Yujie Shi, Apoorva Sarode, Anvay Ukidve and Samir Mitragotri

Bioengineering & Transla Med, 2022, 7
DOI: 10.1002/btm2.10245

Chitosan-based self-healing hydrogel dressing for wound healing

Xingyu Zhang, Yongping Liang, Shengfei Huang and Baolin Guo

Advances in Colloid and Interface Science, 2024, 332, 103267
DOI: 10.1016/j.cis.2024.103267

Smart Injectable Hydrogels for Cancer Immunotherapy

Yu Chao, Qian Chen and Zhuang Liu

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.201902785

Engineered Axonal Tracts as “Living Electrodes” for Synaptic‐Based Modulation of Neural Circuitry

Mijail D. Serruya, James P. Harris, Dayo O. Adewole, Laura A. Struzyna, Justin C. Burrell, Ashley Nemes, Dmitriy Petrov, Reuben H. Kraft, H. Isaac Chen, John A. Wolf and D. Kacy Cullen

Adv Funct Materials, 2018, 28
DOI: 10.1002/adfm.201701183

Nanomaterials as Smart Immunomodulator Delivery System for Enhanced Cancer Therapy

Congshan Yuan, Ya Liu, Ting Wang, Mengjie Sun and Xiguang Chen

ACS Biomater. Sci. Eng., 2020, 6, 4774
DOI: 10.1021/acsbiomaterials.0c00804

Advances in β‐Cyclodextrin‐Driven Self‐Healing Materials: Molecular Design and Multifunctional Applications

Masoumeh Mohamadhoseini and Zahra Mohamadnia

Advanced Materials, 2025, 37
DOI: 10.1002/adma.202507227

Advances of curcumin-loaded hydrogels for multimodal cancer therapeutics

Kexin Tang, Huifang Yang, Yilin Wang, Aonan Liu, Shuoyu Chen, Jiwei Ren, Yuhan Duan and Jing Guo

Discov Onc, 2026
DOI: 10.1007/s12672-026-04908-2

Dynamic and Cell-Infiltratable Hydrogels as Injectable Carrier of Therapeutic Cells and Drugs for Treating Challenging Bone Defects

Qian Feng, Jiankun Xu, Kunyu Zhang, Hao Yao, Nianye Zheng, Lizhen Zheng, Jiali Wang, Kongchang Wei, Xiufeng Xiao, Ling Qin and Liming Bian

ACS Cent. Sci., 2019, 5, 440
DOI: 10.1021/acscentsci.8b00764

Cyclodextrin-containing hydrogels as an intraocular lens for sustained drug release

Xiao Li, Yang Zhao, Kaijie Wang, Lei Wang, Xiaohui Yang, Siquan Zhu and Jonghoon Choi

PLoS ONE, 2017, 12, e0189778
DOI: 10.1371/journal.pone.0189778

Advanced hydrogels based on natural macromolecules: chemical routes to achieve mechanical versatility

C. Mortier, D.C.S. Costa, M.B. Oliveira, H.J. Haugen, S.P. Lyngstadaas, J.J. Blaker and J.F. Mano

Materials Today Chemistry, 2022, 26, 101222
DOI: 10.1016/j.mtchem.2022.101222

Injectable, Guest–Host Assembled Polyethylenimine Hydrogel for siRNA Delivery

Leo L. Wang, Janna N. Sloand, Ann C. Gaffey, Chantel M. Venkataraman, Zhichun Wang, Alen Trubelja, Daniel A. Hammer, Pavan Atluri and Jason A. Burdick

Biomacromolecules, 2017, 18, 77
DOI: 10.1021/acs.biomac.6b01378

Influence of hyaluronic acid modification on CD44 binding towards the design of hydrogel biomaterials

Mi Y. Kwon, Chao Wang, Jonathan H. Galarraga, Ellen Puré, Lin Han and Jason A. Burdick

Biomaterials, 2019, 222, 119451
DOI: 10.1016/j.biomaterials.2019.119451