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Cascade bio-hydroxylation and dehalogenation for one-pot enantioselective synthesis of optically active β-halohydrins from halohydrocarbons

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The taming of oxygen: biocatalytic oxyfunctionalisations

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P450BM3(CYP102A1): connecting the dots

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Bacterial CYP153A monooxygenases for the synthesis of omega-hydroxylated fatty acids

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Biocatalytic synthesis of non-vicinal aliphatic diols

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Expanding the toolbox of organic chemists: directed evolution of P450 monooxygenases as catalysts in regio- and stereoselective oxidative hydroxylation

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A Single Active Site Mutation Inverts Stereoselectivity of 16‐Hydroxylation of Testosterone Catalyzed by Engineered Cytochrome P450 BM3

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ChemBioChem, 2012, 13, 520
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Simulation-Guided Design of Cytochrome P450 for Chemo- and Regioselective Macrocyclic Oxidation

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Selective allylic hydroxylation of acyclic terpenoids by CYP154E1 from Thermobifida fusca YX

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Advances in enzymatic oxyfunctionalization of aliphatic compounds

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Direct Oxidation of Cycloalkanes to Cycloalkanones with Oxygen in Water

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Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity

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Paenibacillus lautus isolated from the Sphenophorus levis gut causes structural and physicochemical changes on polystyrene surface

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Tuning P450 Enzymes as Oxidation Catalysts

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Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin

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Stereo- and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexene

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Kristalle in Minutenschnelle: Sofortige Mikrokristallisation verschiedenster Varianten der CYP102A1‐(P450BM3)‐Hämdomäne

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Expanding an Efficient, Electrically Driven and CNT‐Tagged P450 System into the Third Dimension: A Nanowired CNT‐Containing and Enzyme‐Stabilising 3 D Sol–Gel Electrode

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An Enzyme Cascade Synthesis of Vanillin

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Tuning the Regio‐ and Stereoselectivity of CH Activation in n‐Octanes by Cytochrome P450 BM‐3 with Fluorine Substituents: Evidence for Interactions Between a CF Bond and Aromatic π Systems

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Synthesis of nitrogen-doped hierarchical porous carbon for supercapacitors

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Materials Letters, 2015, 157, 30
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Improving the affinity and activity of CYP101D2 for hydrophobic substrates

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Efficient hydroxylation of cycloalkanes by co-addition of decoy molecules to variants of the cytochrome P450 CYP102A1

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Ligand vacancy channels in pillared inorganic-organic hybrids for electrocatalytic organic oxidation with enzyme-like activities

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Aldehyde and Ketone Synthesis by P450‐Catalyzed Oxidative Deamination of Alkyl Azides

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ChemCatChem, 2016, 8, 2609
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A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants

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Cytochrome P450: taming a wild type enzyme

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Achieving Regio‐ and Enantioselectivity of P450‐Catalyzed Oxidative CH Activation of Small Functionalized Molecules by Structure‐Guided Directed Evolution

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Selective Catalytic Oxidation of CH Bonds with Molecular Oxygen

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Enhancing the Efficiency and Regioselectivity of P450 Oxidation Catalysts by Unnatural Amino Acid Mutagenesis

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ChemBioChem, 2014, 15, 1001
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Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations

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Carving the Active Site of CYP153A7 Monooxygenase for Improving Terminal Hydroxylation of Medium‐Chain Fatty Acids

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Synthesis of chiral 2‐alkanols from n‐alkanes by a P. putida whole‐cell biocatalyst

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Stabilization of the Reductase Domain in the Catalytically Self‐Sufficient Cytochrome P450BM3 by Consensus‐Guided Mutagenesis

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ChemBioChem, 2018, 19, 622
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Cytochrome P450 Catalyzed Oxidative Hydroxylation of Achiral Organic Compounds with Simultaneous Creation of Two Chirality Centers in a Single CH Activation Step

Gheorghe‐Doru Roiban, Rubén Agudo and Manfred T. Reetz

Angew Chem Int Ed, 2014, 53, 8659
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Self-sufficient Cytochrome P450s and their potential applications in biotechnology

Bekir Engin Eser, Yan Zhang, Li Zong and Zheng Guo

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P450-Catalyzed Intramolecular sp3 C–H Amination with Arylsulfonyl Azide Substrates

Ritesh Singh, Melanie Bordeaux and Rudi Fasan

ACS Catal., 2014, 4, 546
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Computation-Aided Engineering of Cytochrome P450 for the Production of Pravastatin

Mark A. Ashworth, Elvira Bombino, René M. de Jong, Hein J. Wijma, Dick B. Janssen, Kirsty J. McLean and Andrew W. Munro

ACS Catal., 2022, 12, 15028
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Direktoxidation von Cycloalkanen zu Cycloalkanonen mit Sauerstoff in Wasser

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Angewandte Chemie, 2013, 125, 2415
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P450-driven plastic-degrading synthetic bacteria

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Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development

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Crystals in Minutes: Instant On‐Site Microcrystallisation of Various Flavours of the CYP102A1 (P450BM3) Haem Domain

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Highly Selective Hydroxylation of Benzene to Phenol by Wild‐type Cytochrome P450BM3 Assisted by Decoy Molecules

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Multi‐Functional Oxidase Activity of CYP102A1 (P450BM3) in the Oxidation of Quinolines and Tetrahydroquinolines

Yushu Li and Luet L. Wong

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A Single Active-Site Mutation of P450BM-3 Dramatically Enhances Substrate Binding and Rate of Product Formation

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Biochemistry, 2011, 50, 8333
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Choose Your Own Adventure: A Comprehensive Database of Reactions Catalyzed by Cytochrome P450 BM3 Variants

Douglas J. Fansher, Jonathan N. Besna, Ali Fendri and Joelle N. Pelletier

ACS Catal., 2024, 14, 5560
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Laboratory evolution of stereoselective enzymes as a means to expand the toolbox of organic chemists

Manfred T. Reetz

Tetrahedron, 2012, 68, 7530
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Discovery of Potent Parthenolide-Based Antileukemic Agents Enabled by Late-Stage P450-Mediated C—H Functionalization

Joshua N. Kolev, Kristen M. O’Dwyer, Craig T. Jordan and Rudi Fasan

ACS Chem. Biol., 2014, 9, 164
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Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1

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