Allium tuberosum-derived nanovesicles with anti-inflammatory properties prevent DSS-induced colitis and modify the gut microbiome

Minkyoung Kang, Minji Kang, Juyeon Lee, Jiseon Yoo, Sujeong Lee and Sangnam Oh

Food Funct., 2024, 15, 7641
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Global trends in surgically based treatment of anal fistula in Crohn’s disease: a bibliometric and visualization analysis

Xingtao Jin, Ye Han, Min Yang, Qianqian Ye, Qingming Wang, De Zheng and Zubing Mei

International Journal of Surgery, 2025, 111, 2578
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Wild Rice-derived exosome-like nanoparticles relieve insulin resistance in HepG2 cells

Haifeng Zhang, Feng Wang, Meng Yuan, Yun Wang, Min Wang, Jiamin Su, Huiling Zhang, Maoyuan Yin, Haiwen Zhang and Chunmei Li

Journal of Functional Foods, 2026, 139, 107189
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Plant-Derived Nanocarriers for Drug Delivery: A Unified Framework Integrating Extracellular Vesicles, Engineered Phytocarriers, Hybrid Platforms, and Bioinspired Systems

Adina-Elena Segneanu, George Dan Mogoşanu, Cornelia Bejenaru, Roxana Kostici and Ludovic Everard Bejenaru

Plants, 2026, 15, 908
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Milk-derived extracellular vesicles: nature’s nanocarriers for drug delivery and therapeutics

Chen Kong, Long-bin Huang, Mei-feng Yang, Ning-ning Yue, Yuan Zhang, Cheng-mei Tian, Yuan-hui Wang, Dao-ru Wei, Rui-yue Shi, Yu-jie Liang, Jun Yao, Li-sheng Wang and De-feng Li

Front. Pharmacol., 2025, 16
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Plant-derived exosomes as next-generation biomaterials: emerging therapeutic platforms for cancer and gut disorders

Rabab Fatima, Sumel Ashique, Joy Das, Sumira Malik, Jutishna Bora, Smita Lata, Anas Islam, Bedanta Bhattacharjee, Soundararajan Sowmiya, Sarvesh Rustagi, Sabina Yasmin, Kumar Venkatesan and Md Yousuf Ansari

Microchemical Journal, 2026, 225, 117973
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Rational design of extracellular vesicles for targeted drug delivery across physiological barriers

Helna M. Baby, Hengli Zhang, Andrew Selvadoss, Tanvi V. Pathrikar and Ambika G. Bajpayee

Nano Today, 2026, 66, 102920
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Plant-derived extracellular vesicles as tools and targets for inflammatory diseases

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J Nanobiotechnol, 2026
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Plant-Derived Extracellular Vesicles as a Novel Frontier in Cancer Therapeutics

Lishan Cui, Giordano Perini, Valentina Palmieri, Marco De Spirito and Massimiliano Papi

Nanomaterials, 2024, 14, 1331
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Human plasma-derived exosomal gel: a biomimetic cargo for the transdermal delivery of methotrexate

Rabia Gul, Wajeeha Khalid, Muhammad Sarfraz, Yousef A. Bin Jardan, Muhammad Ikram, Hamid Bashir, Nadeem Ahmad, Laraib Khan, Bazla Siddiqui, Imran Nazir, Yueshui Jiang and Muhammad Imran Amirzada

Journal of Drug Targeting, 2026, 34, 408
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Current progress of plant-derived exosome-like nanovesicles on the regulation of osteoporosis and osteoarthritis

Xianting Xia, Jinguo Zhu, Xuexin Xu, Weiming Wang, Rui Zhao, Kai Wu, Haoqiang Huang, Yinhua Qian, Zhiwen Luo, Feng Xu, Zhijian Peng and Qing Wang

Annals of Medicine, 2025, 57
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Neuroprotective Effects of Salvia Miltiorrhiza -Derived Extracellular Nanovesicles in Traumatic Brain Injury

Bei-bei Chen, Yao Wang, Ya-nan Li, Cong-cong Han, Jin-xiu Guo, Jun-jun Meng, Wen-xue Sun, Wei-hua Kong, Lei Feng, Rong Rong and Pei Jiang

Journal of Neurotrauma, 2026, 43, 295
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Isolation of plant-derived exosome-like nanovesicles (PDENs) from Aloe vera and their effect on RAW 264.7 and 1BR3 cells as a potential anti-inflammatory and anti-photoaging agent

Anggraini Barlian, Yulia Rahmah, Youngkwan Cho, Salsabila Fitriani, Nafira Fatikha Aulia, Iriawati Iriawati, Noviana Vanawati and Safira Meidina Nursatya

Future Science OA, 2026, 12
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Brucea javanica derived exosome-like nanovesicles deliver miRNAs for cancer therapy

Ge Yan, Qiyao Xiao, Jingyu Zhao, Haoran Chen, Yang Xu, Minhong Tan and Lihua Peng

Journal of Controlled Release, 2024, 367, 425
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Exploring the bioactivity of MicroRNAs Originated from Plant-derived Exosome-like Nanoparticles (PELNs): current perspectives

Kingsley Miyanda Tembo, Xiaohui Wang, Mansoor Bolideei, Qianrui Liu, Farouk Baboni, Mohammad Javad Mehran, Fei Sun and Cong-Yi Wang

J Nanobiotechnol, 2025, 23
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The Use of Plant-Derived Extracellular Vesicles in Regenerative Medicine Applied to Cutaneous Wound Healing

Victoria Pulido-Escribano, Marta Camacho-Cardenosa, Gabriel Dorado, José Manuel Quesada-Gómez, Alfonso Calañas-Continente, María Ángeles Gálvez-Moreno and Antonio Casado-Díaz

Pharmaceutics, 2025, 17, 1531
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The potential of plant-derived vesicles in treating periodontitis and associated systemic diseases: current advances and future directions

Zongshuai Liu, Yonglin Guo, Yifei Deng, Juhua Shao, Xin Huang and Zhengguo Cao

J Nanobiotechnol, 2025, 23
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Tea-derived extracellular vesicles-mediated PDRN delivery activates cAMP-HIF-1α to restore intestinal homeostasis in inflammatory bowel disease

Tingting Cao, Runrun Wan, Xueru Li, Xin Hu, Chengbiao Hu, Yan Liang, Meng Deng, Xiangdong Wang, Zhang Yuan and Chenghu Hu

Materials Today Bio, 2025, 35, 102408
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Plant-derived vesicle-like nanoparticles: A new tool for inflammatory bowel disease and colitis-associated cancer treatment

Xuechun Fang, Junjie Feng, Xingcheng Zhu, Dan Feng and Lei Zheng

Molecular Therapy, 2024, 32, 890
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Plant-derived vesicles: isolation strategies and therapeutic applications

Jiazhong Li, Zhiyi Wang, Feiran Wang, Xiuwei Du and Xiaogang Pang

Front. Plant Sci., 2026, 16
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Edible exosome-like nanoparticles from portulaca oleracea L mitigate DSS-induced colitis via facilitating double-positive CD4+CD8+T cells expansion

Min-zheng Zhu, Hao-ming Xu, Yu-jie Liang, Jing Xu, Ning-ning Yue, Yuan Zhang, Cheng-mei Tian, Jun Yao, Li-sheng Wang, Yu-qiang Nie and De-feng Li

J Nanobiotechnol, 2023, 21
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Plant-derived nanovesicles and therapeutic application

Dokyung Jung, Na-Eun Kim, Sua Kim, Ju-Hyun Bae, Il-Young Jung, Kyung-Won Doh, Byungheon Lee, Do-Kyun Kim, Young-Eun Cho and Moon-Chang Baek

Pharmacology & Therapeutics, 2025, 269, 108832
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Overview of pharmacodynamical research of traditional Chinese medicine on hyperuricemic nephropathy: from the perspective of dual-regulatory effect on the intestines and kidneys

Ting Wang, Li Li, Li Liu, Ruirong Tan, Qinxuan Wu, Xin Zhu, Hua Hua, Ying Dai, Huan Li, Jiuzhou Mao, Junning Zhao and Zhujun Yin

Front. Pharmacol., 2025, 16
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Synthesis and characterization of zinc oxide nanoparticles with Cedrus deodara (Deodar)

Silvi Gautam, Divya Venugopal and Shabaaz Begum

Vegetos, 2024, 38, 1951
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Endoplasmic reticulum stress and exosomes secretion in the pathogenesis of inflammatory bowel disease: a concise summary of research findings

Ashiq Shibili P, Antara Banerjee, Soham Chakraborty, Suresh Babu Kondaveeti, Andrea Porzionato, Silvia Barbon and Surajit Pathak

Front. Pharmacol., 2025, 16
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Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease

Jinling Li, Ting Luo, Dou Wang, Yao Zhao, Yuanxiang Jin, Guiling Yang and Xin Zhang

Journal of Advanced Research, 2025, 68, 63
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MicroRNAs Dependent G‐ELNs Based Intervention Improves Glucose and Fatty Acid Metabolism While Protecting Pancreatic β‐Cells in Type 2 Diabetic Mice

Geetika Bajaj, Diksha Choudhary, Vishal Singh, Nitesh Priyadarshi, Priyanka Garg, Shrikant Subhash Mantri, Vikas Rishi and Nitin Kumar Singhal

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Therapeutic potential of extracellular vesicles in inflammatory diseases

Xiaojian Huang, Shen Zhang and Zhenzhen Wang

Extracellular Vesicle, 2025, 5, 100058
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Multifunctional cosmetic potential of extracellular vesicle‑like nanoparticles derived from the stem of Cannabis sativa in treating pigmentation disorders

Hyeon Lee, Yun Kim, Seo Lee, Su Park, Jae-Min Yuk, Jae Jeong, Young Ryu and Woo Kim

Mol Med Rep, 2025, 31, 1
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Extracellular Vesicles: Novel Potential Therapeutic Agents in Inflammatory Bowel Diseases

Irene Mignini, Giulia Piccirilli, Fabrizio Termite, Mattia Paratore, Giorgio Esposto, Lucrezia Laterza, Franco Scaldaferri, Maria Elena Ainora, Antonio Gasbarrini and Maria Assunta Zocco

Cells, 2023, 13, 90
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Cutting-edge insights into the mechanistic understanding of plant-derived exosome-like nanoparticles: Implications for intestinal homeostasis

Xiyuan Liu, Lihua Mei, Jiaxin Wang, Xuelian Liu, Ying Yang, Zhenlong Wu and Yun Ji

Food Research International, 2025, 208, 116186
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Plant-derived exosome-like nanovesicles: mechanisms and molecular understanding in neurological disorders with potential therapeutic applications

Sevim Isik, Sedra Alhelwani, Aya Sahsahi, Hilal Balcilar and Bercem Yeman-Kiyak

Drug Deliv. and Transl. Res., 2025, 15, 4452
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“One stone three birds”: Andrographis paniculata-derived exosome-like nanoparticles mitigate dextran sulfate sodium-induced colitis

Minzheng Zhu, Shimin Wang, Ningning Yue, Hailan Zhao, Yuan Zhang, Chengmei Tian, Chen Kong, Zhiliang Mai, Longbin Huang, Qianjun Luo, Daoru Wei, Ruiyue Shi, Yuqiang Nie, Yujie Liang, Jun Yao, Lisheng Wang, Jing Sun and Defeng Li

Chinese Medical Journal, 2026, 139, 891
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Sargassum fusiforme-derived Exosome-like Nanoparticles Suppress TLR4/MyD88/NF-κB Pathway to Alleviate Colitis via Modulating Gut Microbiota

Hong Chang, Xinru Wang, Donglin Sui, Yi Liu, Xiaodong Xia and Ningbo Qin

Plant Foods Hum Nutr, 2026, 81
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Advancing functional foods: a systematic analysis of plant-derived exosome-like nanoparticles and their health-promoting properties

Ke Che, Cong Wang and Hao Chen

Front. Nutr., 2025, 12
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RECENT ADVANCES IN PHYTOCHEMICAL-BASED NANOPARTICLES FOR COLON-SPECIFIC DRUG DELIVERY

AVIKUMAR BAWANKAR and LAXMIKANT ZAWAR

Cellulose Chem. Technol., 2025, 59, 1045
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“Revolutionizing Cancer Treatment: The Role of Starch‐Based Nanoparticles in Targeted Therapy”

Devesh U. Kapoor, Geeta Patel and Bhupendra G. Prajapati

Starch Stärke, 2025, 77
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Plant-derived extracellular vesicles: composition, function and clinical potential

Defa Huang, Jie Chen, Minghong Zhao, Haibin Shen, Qing Jin, Dewang Xiao, Zongbo Peng, Tao Chen, Yilei Zhang, Dingyu Rao and Meijin Liu

J Transl Med, 2025, 23
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Unveiling the Potential of Plant-derived Exosomes: A Comprehensive Review

Srishty Jaiswal, Mitali Sethi, Rafquat Rana, Shourya Tripathi, Arun Kumar Trivedi and Manish K. Chourasia

AAPS PharmSciTech, 2026, 27
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Plant-derived exosome-like nanoparticles for microRNA delivery in cancer treatment

Chun Yi, Linzhu Lu, Zhaosheng Li, Qianqian Guo, Longyun Ou, Ruoyu Wang and Xuefei Tian

Drug Deliv. and Transl. Res., 2025, 15, 84
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Nanovesicles from Rosa canina: A Treasure Trove of Antioxidant Potential for Oxidative Stress, Inflammation, and Gut Microbiota Modulation

Gaia Cusumano, Agnese Bertoldi, Eleonora Calzoni, Husam B. R. Alabed, Laura Dorina Dinu, Emanuel Vamanu, Florentina Matei, Gokhan Zengin and Carla Emiliani

Pharmaceuticals, 2025, 18, 1672
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Recent Advances in the Utilization of Dietary-Derived Exosome-like Nanoparticles in Inflammatory Bowel Diseases

Zhu Lin, Yanhan Cui, Jing Wang, Yonghui Yu and Chen Tan

Foods, 2026, 15, 463
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Implementing a food first strategy can transform preventive healthcare

Zhaoshuo Yu, Lijing Ke, Ting Lu, Li Li, Huaiyu Gu and Pingfan Rao

npj Sci Food, 2024, 8
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