A NIR-driven green affording-oxygen microrobot for targeted photodynamic therapy of tumors

Lishan Zhang, Xiaoting Zhang, Hui Ran, Ze Chen, Yicheng Ye, Jiamiao Jiang, Ziwei Hu, Miral Azechi, Fei Peng, Hao Tian, Zhili Xu and Yingfeng Tu

Nanoscale, 2024, 16, 635
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Anti-cancer activity of zinc-tetraphenylporphyrin photosensitizer/dextran-graft-polyacrylamide copolymer/Au(Ag) nanoparticle nanohybrids

Oleg Yeshchenko, Nataliya Kutsevol, Pavlo Virych, Pavlo Khort, Petro Virych, Vasyl Chumachenko and Vasyl Cekhun

RSC Adv., 2024, 14, 5045
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Intelligent catalase-coated MnO2 nanoparticles with programmed oxygen supply and glutathione depletion for enhanced photodynamic therapy

Weijuan Jia, Aoxue Zhang, Haiwei Hou, Yazhong Bu, Di Liu, Ching-Husan Tung and Baoji Du

J. Mater. Chem. B, 2026, 14, 311
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Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy

Yuanyuan Ding, Qingqing Pan, Wenxia Gao, Yuji Pu, Kui Luo and Bin He

Biomater. Sci., 2023, 11, 1182
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Oxygen self-supplying porphyrinic MOFs to alleviate tumor hypoxia for starvation-amplified photodynamic therapy

Shajun Zhu, Jian An, Jia Pu, Xufeng Liang, Shiyue Zhang, Jingjing Ma, Jianxia Zhang, Yujia Meng, Yiqiao Bai, Wenqiang Yu, Yunhan Gao, Yong Yao, Tingting Chen and Yang Wang

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Singlet oxygen storage and controlled release for improving photodynamic therapy against hypoxic tumor

Long Yao, Shaoqi Xie, Yuqing Liu, Liu Mengqi, Jiachen Xia and Bing Lu

Chem. Commun., 2024, 60, 14012
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Multifunctional protein-based self-assembled nanoplatform: overcoming hypoxic tumor microenvironment for enhanced imaging-guided photodynamic therapy

Min Li, Ziyi Cheng, Heng Liu, Kun Dou, Huan Xiao, Linlu Zhao and Fabiao Yu

Biomater. Sci., 2023, 11, 6881
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Triple-Enzyme Mimetic Flexible-Interlaced Ferromagnetic Porous-Organic-Polymer for Self-Adaptive Antibacterial Cascade Therapy via Microenvironment-Reprogramming and Photosensitizer-Aggregation-Suppression

Dandan Xu, Sue Cao, Weiwei Bian, Xiaoming Shi, Dong Zhang, Baolong Zhou, Kun Li, Yan Jiang, Yijun Liu, Yuyu Wang, Junjie Li and Xinkai Han

ACS Appl. Polym. Mater., 2025, 7, 9617
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Glucose‐Modified Porphyrins With Superior Photostability for Enhanced Photodynamic Therapy

Wen‐Yuan Zhang, Bing‐Jie Hou, Wen‐Le Zhang, Bo Wang, Zi‐Han Yang, Neng‐Zhi Jin and Jia‐Cheng Liu

Applied Organom Chemis, 2025, 39
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Adaptive Optimization of Vascular-Targeted Photodynamic Therapy Efficiency Based on Hyperspectral-Photoacoustic Dual-Modality Imaging Feedback

Rongrui Zhang, Jingrui Zhao, Shasha Wang, Jing Lv, Junduo Liu, Jing Liu, Yawen Wang, Lei Fu, Weihui Zeng, Qiangzhou Rong and Cuiping Yao

BME Front, 2026, 7
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Photoacid Generators for Biomedical Applications

Tianzhen Sun, Lin Kang, Hongyou Zhao, Yuxia Zhao and Ying Gu

Advanced Science, 2024, 11
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A paradigm shift from penetration: Material-based solutions for multidimensional spatiotemporal, hypoxic, and optical challenges in cutaneous photodynamic therapy

Xun Feng, Hua Fan, Lubin Zhou, Zhilong Zhao, Mu Yang, Xinxing Sun and Yang Chen

Materials Today Bio, 2026, 37, 102872
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For and against tumor microenvironment: Nanoparticle-based strategies for active cancer therapy

Soroush Karimi, Roksana Bakhshali, Soheil Bolandi, Zahra Zahed, Seyedeh Sahar Mojtaba Zadeh, Masoumeh Kaveh Zenjanab and Rana Jahanban Esfahlan

Materials Today Bio, 2025, 31, 101626
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Photodynamic Therapy and Tumor Microenvironment-Targeting Strategies: A Novel Synergy at the Frontier of Cancer Treatment

Stefani Torna, Vasiliki Gkretsi and Andreas Stylianou

IJMS, 2025, 26, 8588
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Cyanine Nanoassemblies for synergistic cancer therapy: From aggregate-state modulation to Phototheranostic integration

Di Zhang, Shuheng Qin, Hai Xu, Hui Bian, Yuan-Yuan Zhao, Xiao Cheng, Jinrong Zheng, Xiaojun Peng and Juyoung Yoon

Coordination Chemistry Reviews, 2026, 559, 217783
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Activatable chemiluminescence enabled external-light-free photodynamic therapy: From mechanisms, structural designs to theranostics

Yan-Qin He and Jian-Hong Tang

Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 2025, 65, 100724
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Emerging Applications of Chlorella sp. and Spirulina (Arthrospira) sp.

Ana P. Abreu, Rodrigo Martins and João Nunes

Bioengineering, 2023, 10, 955
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Synthesis of asymmetric cationic zinc porphyrin photosensitizer containing thiophene group for photodynamic therapy in vitro and theoretical calculation of DFT

Wen-Yuan Zhang, Gui-Chen Li, Bo Wang, Yan Fan, Xue-Qin Sun, Yi-Xin Yang, Chun-Yan Zhang, Xiao-Xia Feng, Wei-Bing Xu and Jia-Cheng Liu

Journal of Molecular Structure, 2024, 1302, 137497
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Design and clinical advances of smart photoresponsive systems in cancer theranostics

Along Han, Mengqi Liu, Shanshan Li, Ziyang Gong, Lili Tian, Xintao Li, Bolong Xu and Huiyu Liu

Coordination Chemistry Reviews, 2026, 552, 217548
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Advances in Multifunctional Chemotherapeutic Prodrugs for Near‐infrared Fluorescence Imaging‐guided Therapy

Jiayu Zeng, Minhui Liu, Songjiao Li, Dan Cheng, Longwei He and Lin Yuan

ChemBioChem, 2023, 24
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Light‐Driven Green‐Fabricated Artificial Intelligence‐Enabled Micro/Nanorobots for Multimodal Phototherapeutic Management of Bladder Cancer

Chi‐Hung Hsiao, Yung‐Wei Lin, Chia‐Hung Liu, Hieu Trung Nguyen and Andrew E.‐Y. Chuang

Adv Healthcare Materials, 2024, 13
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One‐pot synthesis of POM‐CaO2@ZIF‐8 nanoparticles with self‐supply of H2O2 for electrically enhanced chemodynamic therapy

Tiedong Sun, Zhengya Yue, Yan Song, Jiatong Ni, Wenxin Wang, Junge Zhao, Jialun Li, Yuan Sun and Bin Li

Applied Organom Chemis, 2022, 36
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Correction of Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) for Tissue Optical Properties in Photofrin-Mediated Photodynamic Therapy

Weibing Yang, Madelyn Johnson, Baozhu Lu, Dennis Sourvanos, Hongjing Sun, Andreea Dimofte, Vikas Vikas, Theresa M. Busch, Robert H. Hadfield, Brian C. Wilson and Timothy C. Zhu

Antioxidants, 2024, 13, 1458
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Bidirectional pH-responsive O2@perfluorocarbon@cyanine dyes for cascade photothermal therapy and oxygen-releasing enhanced photodynamic tumor treatment

Miao Li, Zichuang Ye, Yining Wang, Hao Kong, Jinlong Zhou, Jianfang Cao, Honglei Zhan, Qian Li and Xiaojun Peng

Chemical Engineering Journal, 2025, 518, 164690
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Magnetothermal-regulated dual-atom nanozyme amplifying cascade ROS generation and NK cell–mediated immunotherapy in metastatic breast cancer

Di Zhang, Shuheng Qin, Lingzi Feng, Juyoung Yoon, Zhongying Jiang and Yong Hu

Chinese Chemical Letters, 2026, 112584
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Synergistic photodynamic and photothermal therapy with biomaterials for accelerated wound healing

Yijia Yuan, Ruliang Pan, Chunyu Su, Li He, Rui Liang, Taotao Bai, Limin Liu, Baoguo Li and Yuli Li

Materials & Design, 2026, 264, 115781
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“Green” gas-generation strategy to combine cancer phototherapy for remarkably enhanced efficacy

Jiahui Wu, Gege Zhang, Mi Zou, Qiong Huang, Yanling Zhang, Yajie Sui, Shuang Wu, Jianming Yang, Qiaojun Fang and Pingping Liang

Nano TransMed, 2025, 4, 100090
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Copper-coordinated nanoassemblies based on photosensitizer-chemo prodrugs and checkpoint inhibitors for enhanced apoptosis-cuproptosis and immunotherapy

Wenlong Liang, Chao Han, Danlu Zhang, Chunlei Liu, Minghao Zhu, Feijie Xu, Cheng Fang, Shuo Zhang, Chunzhao Liu and Yongxin Li

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Targeting the breast tumor microenvironment by plant-derived products and their nanoformulations

Hongpeng Zhang and Yanshu Li

Journal of Drug Delivery Science and Technology, 2024, 93, 105432
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Engineered photoresponsive biohybrids for tumor therapy

Xiaocheng Wang, Yazhi Sun and Daniel Wangpraseurt

Smart Medicine, 2023, 2
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Qian Wang, Yuping Suo, Rui Shi and Yulan Wang

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Biomedical engineered nanomaterials to alleviate tumor hypoxia for enhanced photodynamic therapy

Chunmei Lai, Bangyue Luo, Jiangwen Shen and Jingwei Shao

Pharmacological Research, 2022, 186, 106551
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Orthogonal Optimization, Characterization, and In Vitro Anticancer Activity Evaluation of a Hydrogen Peroxide-Responsive and Oxygen-Reserving Nanoemulsion for Hypoxic Tumor Photodynamic Therapy

Liang Hong, Jianman Wang, Yi Zhou, Guofu Shang, Tao Guo, Hailong Tang, Jiangmin Li, Yali Luo, Xiangyu Zeng, Zhu Zeng and Zuquan Hu

Cancers, 2023, 15, 1576
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Smart Nanoparticles for Chemo-Based Combinational Therapy

Binita Shrestha, Lijun Wang, Eric M. Brey, Gabriela Romero Uribe and Liang Tang

Pharmaceutics, 2021, 13, 853
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Synergistic Cancer treatment strategies using platinum-porphyrin conjugates

Md Ashif Ali, Kang Ho Chu, Du Yeol Ryu and Woo-Dong Jang

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Boronophenylalanine‐Functionalized Platinum Nanozymes Sensitizing Neutron Capture Therapy

Xiangxia Li, Guiyuan Chen, Bing Hong, Changqing Guo, Huanjun Zhu, Qilong Zhu, Yuanyu Liu, Zilong Li, Lingling Li, Chao Gao, Peng Lu, Dong Qian, Lizhen Liang, Yujie Xiong and Yuanzeng Min

Adv Funct Materials, 2025, 35
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Alleviating the hypoxic tumor microenvironment with MnO2-coated CeO2 nanoplatform for magnetic resonance imaging guided radiotherapy

Fen Pi, Xuanru Deng, Qian Xue, Lan Zheng, Hongxing Liu, Fang Yang and Tianfeng Chen

J Nanobiotechnol, 2023, 21
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Protein-Confined Rotor Strategy for Quantum Yield Enhancement in Supramolecular Photosensitizers toward Sentinel Lymph Node-Targeted Photodynamic Immunoactivation

Shuheng Qin, Xiao Cheng, Ziqi Zhou, Xinran Zhang, Jiayang Chen, Peipei Xu, Ting Wu and Yong Hu

ACS Nano, 2025, 19, 24985
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Recent Strategies to Address Hypoxic Tumor Environments in Photodynamic Therapy

Yuyin Du, Jianhua Han, Feiyang Jin and Yongzhong Du

Pharmaceutics, 2022, 14, 1763
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Advances in Cancer Treatment Through Nanotheranostics and Emerging Therapies

Victor Akpe and Ian E. Cock

JNT, 2025, 6, 29
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Tumor homing-penetrating and nanoenzyme-augmented 2D phototheranostics against hypoxic solid tumors

Chunhui Wu, Yingxue Zhang, Xiaodan Wei, Ningxi Li, Honglin Huang, Zhengxin Xie, Hanxi Zhang, Geng Yang, Mengyue Li, Tingting Li, Hong Yang, Shun Li, Xiang Qin and Yiyao Liu

Acta Biomaterialia, 2022, 150, 391
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Cupric-ion-promoted fabrication of oxygen-replenishing nanotherapeutics for synergistic chemo and photodynamic therapy against tumor hypoxia

Lin He, Feijie Xu, Yongxin Li, Honglin Jin and Pui-Chi Lo

Acta Biomaterialia, 2023, 162, 57
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A BODIPY-modified polymeric micelle for sustaining enhanced photodynamic therapy

Yun-Chang Zhang, Lan She, Zi-Yue Xu, Ze-Kun Wang, Zhiqiang Ma, Feng Yang and Zhan-Ting Li

Chinese Chemical Letters, 2022, 33, 3277
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Photosensitizer‐Mesoporous Silica Nanoparticles Combination for Enhanced Photodynamic Therapy†

Ruth Prieto‐Montero, Teresa Arbeloa and Virginia Martínez‐Martínez

Photochem & Photobiology, 2023, 99, 882
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